Rab28 (RAB28, member RAS oncogene family) - Rat Genome Database

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Gene: Rab28 (RAB28, member RAS oncogene family) Rattus norvegicus
Analyze
Symbol: Rab28
Name: RAB28, member RAS oncogene family
RGD ID: 620891
Description: Enables GTP binding activity. Predicted to be involved in intracellular protein transport. Located in ciliary basal body and ciliary rootlet. Human ortholog(s) of this gene implicated in cone-rod dystrophy 18. Orthologous to human RAB28 (RAB28, member RAS oncogene family); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3H-1,2-dithiole-3-thione; 4,4'-sulfonyldiphenol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: rab-26; ras-related protein Rab-28
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81473,458,386 - 73,535,367 (+)NCBIGRCr8
mRatBN7.21469,245,846 - 69,322,968 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1469,245,854 - 69,322,967 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1473,699,920 - 73,776,814 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01474,936,296 - 75,013,195 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01471,394,651 - 71,471,545 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01473,888,968 - 73,963,209 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1473,889,213 - 73,963,202 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01473,894,339 - 73,970,535 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41474,401,541 - 74,481,472 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11474,403,931 - 74,483,862 (+)NCBI
Celera1468,177,742 - 68,254,714 (+)NCBICelera
Cytogenetic Map14q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function
GDP binding  (ISO,ISS)
GTP binding  (IDA,IEA,ISO,ISS)
GTPase activity  (IBA,IEA,TAS)
protein binding  (ISO)

References

References - curated
# Reference Title Reference Citation
1. Alternative mRNA splicing of the novel GTPase Rab28 generates isoforms with different C-termini. Brauers A, etal., Eur J Biochem 1996 May 1;237(3):833-40.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
4. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
5. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
6. GOA pipeline RGD automated data pipeline
7. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
9. Mutations in RAB28, encoding a farnesylated small GTPase, are associated with autosomal-recessive cone-rod dystrophy. Roosing S, etal., Am J Hum Genet. 2013 Jul 11;93(1):110-7. doi: 10.1016/j.ajhg.2013.05.005. Epub 2013 Jun 6.
10. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
Additional References at PubMed
PMID:19026641   PMID:20937701   PMID:23457503   PMID:23716698  


Genomics

Comparative Map Data
Rab28
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81473,458,386 - 73,535,367 (+)NCBIGRCr8
mRatBN7.21469,245,846 - 69,322,968 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1469,245,854 - 69,322,967 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1473,699,920 - 73,776,814 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01474,936,296 - 75,013,195 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01471,394,651 - 71,471,545 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01473,888,968 - 73,963,209 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1473,889,213 - 73,963,202 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01473,894,339 - 73,970,535 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41474,401,541 - 74,481,472 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11474,403,931 - 74,483,862 (+)NCBI
Celera1468,177,742 - 68,254,714 (+)NCBICelera
Cytogenetic Map14q21NCBI
RAB28
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38413,367,724 - 13,484,340 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl413,361,354 - 13,484,365 (-)EnsemblGRCh38hg38GRCh38
GRCh37413,369,348 - 13,485,964 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36412,978,480 - 13,095,054 (-)NCBINCBI36Build 36hg18NCBI36
Build 34413,046,439 - 13,162,043NCBI
Celera413,835,557 - 13,952,196 (-)NCBICelera
Cytogenetic Map4p15.33NCBI
HuRef412,707,191 - 12,823,838 (-)NCBIHuRef
CHM1_1413,367,911 - 13,484,587 (-)NCBICHM1_1
T2T-CHM13v2.0413,347,405 - 13,464,023 (-)NCBIT2T-CHM13v2.0
Rab28
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39541,782,316 - 41,865,535 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl541,782,319 - 41,865,500 (-)EnsemblGRCm39 Ensembl
GRCm38541,624,973 - 41,708,193 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl541,624,976 - 41,708,157 (-)EnsemblGRCm38mm10GRCm38
MGSCv37542,016,215 - 42,099,394 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36541,913,224 - 41,996,403 (-)NCBIMGSCv36mm8
Celera539,079,605 - 39,165,754 (-)NCBICelera
Cytogenetic Map5B3NCBI
cM Map522.58NCBI
Rab28
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495548010,258,028 - 10,374,021 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495548010,220,811 - 10,374,021 (+)NCBIChiLan1.0ChiLan1.0
RAB28
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2313,632,294 - 13,740,915 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1413,830,843 - 13,939,470 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v047,793,007 - 7,901,614 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1413,093,806 - 13,202,569 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl413,093,806 - 13,202,569 (-)Ensemblpanpan1.1panPan2
RAB28
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1366,601,543 - 66,738,055 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl297,185,678 - 7,187,043 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha369,125,221 - 69,262,331 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0367,205,886 - 67,343,296 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl367,205,883 - 67,318,491 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1366,583,562 - 66,720,524 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0366,776,564 - 66,913,849 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0367,146,395 - 67,283,217 (+)NCBIUU_Cfam_GSD_1.0
Rab28
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440528560,364,371 - 60,438,633 (+)NCBIHiC_Itri_2
SpeTri2.0NW_00493647714,066,063 - 14,140,310 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RAB28
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl88,774,790 - 9,125,240 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.188,870,795 - 9,125,253 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.288,643,826 - 8,662,471 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Sscrofa10.288,509,557 - 8,525,399 (+)NCBISscrofa10.2Sscrofa10.2susScr3
RAB28
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12736,699,000 - 36,849,208 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2736,698,770 - 36,818,979 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604783,447,966 - 83,567,824 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Rab28
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475518,117,400 - 18,212,545 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475518,117,612 - 18,211,715 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Rab28
249 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:84
Count of miRNA genes:72
Interacting mature miRNAs:78
Transcripts:ENSRNOT00000041310
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
631839Niddm37Non-insulin dependent diabetes mellitus QTL 373.37blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)141103062295876975Rat
70187Pancm5Pancreatic morphology QTL 516.7pancreas mass (VT:0010144)pancreas weight to body weight ratio (CMO:0000630)143032009280829842Rat
2313048Bss84Bone structure and strength QTL 843.10.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)143766971982669719Rat
2313084Bss83Bone structure and strength QTL 832.90.0001tibia size trait (VT:0100001)tibia midshaft endosteal cross-sectional area (CMO:0001716)143766971982669719Rat
2313089Bss81Bone structure and strength QTL 813.40.0001body length (VT:0001256)body length, nose to rump (CMO:0000079)143766971982669719Rat
2313100Bss82Bone structure and strength QTL 8230.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)143766971982669719Rat
738037Hcas6Hepatocarcinoma susceptibility QTL 62.93liver integrity trait (VT:0010547)liver nonremodeling tumorous lesion volume to total liver volume ratio (CMO:0001464)143905723783368335Rat
70214Niddm28Non-insulin dependent diabetes mellitus QTL 284.06blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)143999825175582726Rat
631523Pia13Pristane induced arthritis QTL 133.3joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)144079346098037301Rat
1300136Rf22Renal function QTL 223.9renal blood flow trait (VT:2000006)absolute change in renal vascular resistance (CMO:0001900)144226252995023211Rat
1549834Scl45Serum cholesterol level QTL 455.8blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)145002321195023211Rat
2300197Scl59Serum cholesterol level QTL 59blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)1455147478100147478Rat
9590294Uminl4Urine mineral level QTL 45.660.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)1455624247100624247Rat
9589034Epfw11Epididymal fat weight QTL 1160.001epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)1455624247100624247Rat
2317879Alcrsp27Alcohol response QTL 273.30.63response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)1456631369101631369Rat
634328Hc5Hypercalciuria QTL 52.3urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)1458184885103184885Rat
70153Bp59Blood pressure QTL 593.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)146875779683368335Rat

Markers in Region
BE105600  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_5.01473,969,442 - 73,969,643NCBIRnor5.0
RGSC_v3.41474,479,694 - 74,479,910UniSTSRGSC3.4
Celera1468,253,176 - 68,253,392UniSTS
Cytogenetic Map14q21UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 43 57 41 19 41 8 11 74 35 41 11 8
Low
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_053978 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008770195 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008770196 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008770197 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008770198 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017599054 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063272805 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063272806 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005492874 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005492875 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005492877 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005492878 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide BC072512 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473963 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000014 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X78606 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000041310   ⟹   ENSRNOP00000050260
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1469,245,902 - 69,322,966 (+)Ensembl
Rnor_6.0 Ensembl1473,889,213 - 73,963,202 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000081033   ⟹   ENSRNOP00000071725
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1469,245,863 - 69,322,967 (+)Ensembl
Rnor_6.0 Ensembl1473,889,337 - 73,963,202 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000098628   ⟹   ENSRNOP00000089058
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1469,245,868 - 69,315,075 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000117951   ⟹   ENSRNOP00000080796
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1469,245,854 - 69,322,967 (+)Ensembl
RefSeq Acc Id: NM_053978   ⟹   NP_446430
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81473,458,428 - 73,535,367 (+)NCBI
mRatBN7.21469,246,026 - 69,322,967 (+)NCBI
Rnor_6.01473,889,337 - 73,963,208 (+)NCBI
Rnor_5.01473,894,339 - 73,970,535 (+)NCBI
RGSC_v3.41474,401,541 - 74,481,472 (+)RGD
Celera1468,177,742 - 68,254,714 (+)RGD
Sequence:
RefSeq Acc Id: XM_008770195   ⟹   XP_008768417
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81473,458,386 - 73,534,622 (+)NCBI
mRatBN7.21469,245,846 - 69,322,968 (+)NCBI
Rnor_6.01473,888,968 - 73,963,209 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008770196   ⟹   XP_008768418
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81473,458,386 - 73,535,367 (+)NCBI
mRatBN7.21469,245,846 - 69,322,968 (+)NCBI
Rnor_6.01473,888,968 - 73,963,209 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008770197   ⟹   XP_008768419
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81473,459,050 - 73,535,367 (+)NCBI
mRatBN7.21469,246,607 - 69,322,968 (+)NCBI
Rnor_6.01473,889,620 - 73,963,209 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008770198   ⟹   XP_008768420
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81473,458,386 - 73,535,367 (+)NCBI
mRatBN7.21469,245,846 - 69,322,968 (+)NCBI
Rnor_6.01473,888,968 - 73,963,209 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017599054   ⟹   XP_017454543
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81473,458,386 - 73,535,367 (+)NCBI
mRatBN7.21469,245,846 - 69,322,968 (+)NCBI
Rnor_6.01473,888,968 - 73,963,209 (+)NCBI
Sequence:
RefSeq Acc Id: XM_063272805   ⟹   XP_063128875
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81473,459,011 - 73,534,622 (+)NCBI
RefSeq Acc Id: XM_063272806   ⟹   XP_063128876
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81473,459,050 - 73,535,367 (+)NCBI
RefSeq Acc Id: XR_005492874
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81473,458,386 - 73,535,367 (+)NCBI
mRatBN7.21469,245,849 - 69,322,968 (+)NCBI
RefSeq Acc Id: XR_005492875
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81473,458,386 - 73,535,367 (+)NCBI
mRatBN7.21469,245,849 - 69,322,968 (+)NCBI
RefSeq Acc Id: XR_005492877
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81473,458,386 - 73,535,367 (+)NCBI
mRatBN7.21469,245,849 - 69,322,968 (+)NCBI
RefSeq Acc Id: XR_005492878
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81473,458,386 - 73,535,367 (+)NCBI
mRatBN7.21469,245,849 - 69,322,968 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: NP_446430   ⟸   NM_053978
- UniProtKB: P51158 (UniProtKB/Swiss-Prot),   A6IJR3 (UniProtKB/TrEMBL),   A6IJR0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008768417   ⟸   XM_008770195
- Peptide Label: isoform X1
- UniProtKB: Q6IN03 (UniProtKB/TrEMBL),   A6IJR0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008768418   ⟸   XM_008770196
- Peptide Label: isoform X1
- UniProtKB: Q6IN03 (UniProtKB/TrEMBL),   A6IJR0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008768420   ⟸   XM_008770198
- Peptide Label: isoform X4
- UniProtKB: A0A8I5ZQN9 (UniProtKB/TrEMBL),   A6IJQ9 (UniProtKB/TrEMBL),   A6IJR0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008768419   ⟸   XM_008770197
- Peptide Label: isoform X2
- UniProtKB: A0A8I6GGV5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017454543   ⟸   XM_017599054
- Peptide Label: isoform X5
- UniProtKB: A6IJR1 (UniProtKB/TrEMBL),   A6IJR0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000050260   ⟸   ENSRNOT00000041310
RefSeq Acc Id: ENSRNOP00000071725   ⟸   ENSRNOT00000081033
RefSeq Acc Id: ENSRNOP00000089058   ⟸   ENSRNOT00000098628
RefSeq Acc Id: ENSRNOP00000080796   ⟸   ENSRNOT00000117951
RefSeq Acc Id: XP_063128875   ⟸   XM_063272805
- Peptide Label: isoform X3
- UniProtKB: A0A8I6GGV5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063128876   ⟸   XM_063272806
- Peptide Label: isoform X6
- UniProtKB: A6IJR0 (UniProtKB/TrEMBL)

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P51158-F1-model_v2 AlphaFold P51158 1-221 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13699368
Promoter ID:EPDNEW_R9886
Type:initiation region
Name:Rab28_1
Description:RAB28, member RAS oncogene family
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01473,889,157 - 73,889,217EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:620891 AgrOrtholog
BioCyc Gene G2FUF-15467 BioCyc
Ensembl Genes ENSRNOG00000017074 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSRNOG00055015372 UniProtKB/Swiss-Prot
  ENSRNOG00060024433 UniProtKB/Swiss-Prot
  ENSRNOG00065005501 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000041310.5 UniProtKB/TrEMBL
  ENSRNOT00000081033 ENTREZGENE
  ENSRNOT00000081033.2 UniProtKB/Swiss-Prot
  ENSRNOT00000098628.1 UniProtKB/TrEMBL
  ENSRNOT00000117951.1 UniProtKB/TrEMBL
  ENSRNOT00055026244 UniProtKB/Swiss-Prot
  ENSRNOT00060042339 UniProtKB/Swiss-Prot
  ENSRNOT00065008135 UniProtKB/Swiss-Prot
Gene3D-CATH 3.40.50.300 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7104824 IMAGE-MGC_LOAD
InterPro P-loop_NTPase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Small_GTP-bd_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Small_GTPase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:117049 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGC_CLONE MGC:91546 IMAGE-MGC_LOAD
NCBI Gene 117049 ENTREZGENE
PANTHER DRAB5-RELATED UniProtKB/TrEMBL
  PTHR47978 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR47978:SF55 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RAS-RELATED PROTEIN RAB-28 UniProtKB/TrEMBL
Pfam Ras UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Roc UniProtKB/TrEMBL
PhenoGen Rab28 PhenoGen
PRINTS RASTRNSFRMNG UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE RAB UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RAS UniProtKB/TrEMBL
RatGTEx ENSRNOG00000017074 RatGTEx
  ENSRNOG00055015372 RatGTEx
  ENSRNOG00060024433 RatGTEx
  ENSRNOG00065005501 RatGTEx
SMART RAB UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RAN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RAS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RHO UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF52540 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8I5ZQN9 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6GGV5 ENTREZGENE, UniProtKB/TrEMBL
  A6IJQ9 ENTREZGENE, UniProtKB/TrEMBL
  A6IJR0 ENTREZGENE, UniProtKB/TrEMBL
  A6IJR1 ENTREZGENE, UniProtKB/TrEMBL
  A6IJR3 ENTREZGENE, UniProtKB/TrEMBL
  A6IJR5_RAT UniProtKB/TrEMBL
  A6IJR6_RAT UniProtKB/TrEMBL
  P51158 ENTREZGENE
  Q6IN03 ENTREZGENE, UniProtKB/TrEMBL
  RAB28_RAT UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2004-02-26 Rab28  RAB28, member RAS oncogene family      Symbol and Name status set to approved 625702 APPROVED
2002-08-07 Rab28  RAB28, member RAS oncogene family      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_transcript has two splicing forms which differ only by a 95-bp insertion within the coding region 633759