Dnajb2 (DnaJ heat shock protein family (Hsp40) member B2) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: Dnajb2 (DnaJ heat shock protein family (Hsp40) member B2) Rattus norvegicus
Analyze
Symbol: Dnajb2
Name: DnaJ heat shock protein family (Hsp40) member B2
RGD ID: 1591035
Description: Predicted to enable several functions, including Hsp70 protein binding activity; enzyme binding activity; and modification-dependent protein binding activity. Predicted to be involved in several processes, including proteasomal protein catabolic process; protein folding; and regulation of protein metabolic process. Predicted to be located in several cellular components, including endoplasmic reticulum membrane; nuclear membrane; and perinuclear region of cytoplasm. Predicted to be part of proteasome complex. Predicted to be active in cytosol. Human ortholog(s) of this gene implicated in autosomal recessive distal hereditary motor neuronopathy 5. Orthologous to human DNAJB2 (DnaJ heat shock protein family (Hsp40) member B2); PARTICIPATES IN Endoplasmic Reticulum-associated degradation pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3-chloropropane-1,2-diol; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: DnaJ (Hsp40) homolog, subfamily B, member 2; dnaJ homolog subfamily B member 2; hypothetical protein LOC689593; LOC689593; similar to DnaJ (Hsp40) homolog, subfamily B, member 10 isoform 2
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8984,179,702 - 84,187,942 (+)NCBIGRCr8
mRatBN7.2976,731,060 - 76,739,278 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl976,731,065 - 76,739,277 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx985,175,912 - 85,184,076 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0990,304,803 - 90,312,970 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0988,691,018 - 88,699,186 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0982,436,453 - 82,444,669 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl982,436,458 - 82,444,668 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0982,205,714 - 82,213,930 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4974,517,647 - 74,525,857 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera974,301,465 - 74,309,675 (+)NCBICelera
Cytogenetic Map9q33NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
3. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:7957263   PMID:9553041   PMID:12477932   PMID:12754272   PMID:15936278   PMID:16604191   PMID:20889486   PMID:21231916   PMID:21625540   PMID:22219199   PMID:22871113   PMID:24023695  
PMID:28031292  


Genomics

Comparative Map Data
Dnajb2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8984,179,702 - 84,187,942 (+)NCBIGRCr8
mRatBN7.2976,731,060 - 76,739,278 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl976,731,065 - 76,739,277 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx985,175,912 - 85,184,076 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0990,304,803 - 90,312,970 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0988,691,018 - 88,699,186 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0982,436,453 - 82,444,669 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl982,436,458 - 82,444,668 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0982,205,714 - 82,213,930 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4974,517,647 - 74,525,857 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera974,301,465 - 74,309,675 (+)NCBICelera
Cytogenetic Map9q33NCBI
DNAJB2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382219,279,366 - 219,286,895 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2219,279,342 - 219,286,898 (+)EnsemblGRCh38hg38GRCh38
GRCh372220,144,088 - 220,151,617 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362219,852,284 - 219,859,866 (+)NCBINCBI36Build 36hg18NCBI36
Build 342219,969,602 - 219,977,127NCBI
Celera2213,913,742 - 213,921,325 (+)NCBICelera
Cytogenetic Map2q35NCBI
HuRef2211,997,126 - 212,004,708 (+)NCBIHuRef
CHM1_12220,149,887 - 220,157,470 (+)NCBICHM1_1
T2T-CHM13v2.02219,764,122 - 219,771,651 (+)NCBIT2T-CHM13v2.0
Dnajb2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39175,213,039 - 75,222,336 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl175,213,050 - 75,222,336 (+)EnsemblGRCm39 Ensembl
GRCm38175,236,395 - 75,245,692 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl175,236,406 - 75,245,692 (+)EnsemblGRCm38mm10GRCm38
MGSCv37175,232,998 - 75,242,267 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36175,119,635 - 75,128,838 (+)NCBIMGSCv36mm8
Celera175,727,318 - 75,736,588 (+)NCBICelera
Cytogenetic Map1C4NCBI
cM Map138.64NCBI
Dnajb2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545314,148,070 - 14,154,670 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495545314,147,286 - 14,154,396 (-)NCBIChiLan1.0ChiLan1.0
DNAJB2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v213121,909,722 - 121,917,299 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12B121,924,702 - 121,932,264 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02B106,536,846 - 106,544,430 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12B225,127,967 - 225,135,556 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B225,127,967 - 225,135,556 (+)Ensemblpanpan1.1panPan2
DNAJB2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13725,826,496 - 25,834,011 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3725,827,713 - 25,833,144 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3726,652,500 - 26,659,869 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03725,841,856 - 25,849,227 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3725,841,844 - 25,849,222 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13725,746,217 - 25,753,596 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03725,681,582 - 25,688,947 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03725,702,255 - 25,709,637 (+)NCBIUU_Cfam_GSD_1.0
Dnajb2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303175,347,122 - 175,354,398 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365691,689,507 - 1,698,954 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365691,689,926 - 1,697,179 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DNAJB2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl15121,319,982 - 121,335,991 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.115121,319,897 - 121,335,927 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.215134,355,341 - 134,363,197 (+)NCBISscrofa10.2Sscrofa10.2susScr3
DNAJB2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.110105,185,987 - 105,193,749 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl10105,186,608 - 105,194,574 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604094,203,755 - 94,211,383 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Dnajb2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248235,730,386 - 5,738,459 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248235,730,553 - 5,737,668 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Dnajb2
27 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:384
Count of miRNA genes:213
Interacting mature miRNAs:258
Transcripts:ENSRNOT00000026467
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
7411571Bw138Body weight QTL 13814.30.001body mass (VT:0001259)body weight gain (CMO:0000420)93253550577535505Rat
11353957Bmd92Bone mineral density QTL 920.01tibia mineral mass (VT:1000283)volumetric bone mineral density (CMO:0001553)94611419991114199Rat
61385Edpm9Estrogen-dependent pituitary mass QTL 93.430.05pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)963869687108869687Rat
70218Cm28Cardiac mass QTL 288.30.0001heart mass (VT:0007028)heart wet weight (CMO:0000069)92526804479271759Rat
724544Uae9Urinary albumin excretion QTL 94.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)925268044114175309Rat
1578760Cm53Cardiac mass QTL 533.30.0001heart mass (VT:0007028)heart wet weight (CMO:0000069)956771635101771635Rat
1581580Uae34Urinary albumin excretion QTL 34urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)96207227596470995Rat
1581517Bp284Blood pressure QTL 284arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)97665062976771824Rat
12879506Pur33Proteinuria QTL 33urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)94464992189649921Rat
1354626Bvd1Brain ventricular dilatation QTL 13.730.001brain ventricle morphology trait (VT:0000822)hydrocephalus severity score (CMO:0001881)975712843111552878Rat
731164Uae25Urinary albumin excretion QTL 253.50.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)925661188100929786Rat
10058949Gmadr5Adrenal mass QTL 520.014adrenal gland mass (VT:0010420)both adrenal glands wet weight to body weight ratio (CMO:0002411)94279151387976209Rat
1578757Pur6Proteinuria QTL 63.30.005urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)96207227596470995Rat
631656Bp108Blood pressure QTL 1085.970.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)94859825193598251Rat
2303170Bp332Blood pressure QTL 3323.730.027arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)95584784177026453Rat
8662828Vetf6Vascular elastic tissue fragility QTL 63.9artery integrity trait (VT:0010639)patent ductus arteriosus score (CMO:0002566)93696235992058970Rat
61352Bp34Blood pressure QTL 345arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)94249534379271511Rat
724515Uae16Urinary albumin excretion QTL 168urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)958163035100929646Rat
731171Glom6Glomerulus QTL 62.80.0003kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)964573531109573531Rat
1598834Memor11Memory QTL 112.5exploratory behavior trait (VT:0010471)average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)93696235977814038Rat
70186Niddm26Non-insulin dependent diabetes mellitus QTL 263.87blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)92207116986369743Rat
7207814Bmd91Bone mineral density QTL 913.5femur size trait (VT:1000369)femoral neck cross-sectional area (CMO:0001697)92375414483851531Rat
6903941Pur31Proteinuria QTL 310.036urine total protein amount (VT:0000032)urine protein excretion rate (CMO:0000759)94019418885194188Rat
2303180Bp333Blood pressure QTL 3330.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)95662771378595166Rat
2290450Scl57Serum cholesterol level QTL 574.15blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)93696235995410867Rat
11353949Bp393Blood pressure QTL 393arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)94019418885194188Rat
11353951Bp394Blood pressure QTL 394arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)94464992189649921Rat
10054125Srcrt7Stress Responsive Cort QTL 73.330.0011blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)9187073594Rat
1300134Bp185Blood pressure QTL 1853.73arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)961381434104821652Rat
7411656Foco26Food consumption QTL 269.80.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)93253550577535505Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001109541 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001399115 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001399116 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001399117 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001399118 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006245279 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006245280 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006245281 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017596644 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039084218 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063267754 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063267755 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063267756 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063267757 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063267758 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063267759 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063267761 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063267762 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide BC166710 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH474004 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000009 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000026467   ⟹   ENSRNOP00000026467
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl976,731,065 - 76,739,277 (+)Ensembl
Rnor_6.0 Ensembl982,436,458 - 82,444,668 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000081958   ⟹   ENSRNOP00000074369
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl976,731,097 - 76,739,273 (+)Ensembl
Rnor_6.0 Ensembl982,436,516 - 82,444,668 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000095829   ⟹   ENSRNOP00000085337
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl976,731,426 - 76,739,259 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000098165   ⟹   ENSRNOP00000076642
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl976,731,065 - 76,739,277 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000102574   ⟹   ENSRNOP00000092193
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl976,731,534 - 76,739,277 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000111890   ⟹   ENSRNOP00000086434
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl976,731,276 - 76,739,099 (+)Ensembl
RefSeq Acc Id: NM_001109541   ⟹   NP_001103011
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8984,179,768 - 84,187,942 (+)NCBI
mRatBN7.2976,731,103 - 76,739,278 (+)NCBI
Rnor_6.0982,436,458 - 82,444,668 (+)NCBI
Rnor_5.0982,205,714 - 82,213,930 (+)NCBI
RGSC_v3.4974,517,647 - 74,525,857 (+)RGD
Celera974,301,465 - 74,309,675 (+)RGD
Sequence:
RefSeq Acc Id: NM_001399115   ⟹   NP_001386044
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8984,179,768 - 84,187,942 (+)NCBI
mRatBN7.2976,731,103 - 76,739,278 (+)NCBI
RefSeq Acc Id: NM_001399116   ⟹   NP_001386045
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8984,179,768 - 84,187,942 (+)NCBI
mRatBN7.2976,731,103 - 76,739,278 (+)NCBI
RefSeq Acc Id: NM_001399117   ⟹   NP_001386046
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8984,179,768 - 84,187,942 (+)NCBI
mRatBN7.2976,731,103 - 76,739,278 (+)NCBI
RefSeq Acc Id: NM_001399118   ⟹   NP_001386047
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8984,179,768 - 84,187,942 (+)NCBI
mRatBN7.2976,731,103 - 76,739,278 (+)NCBI
RefSeq Acc Id: XM_006245279   ⟹   XP_006245341
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8984,179,729 - 84,187,942 (+)NCBI
mRatBN7.2976,731,067 - 76,739,278 (+)NCBI
Rnor_6.0982,436,454 - 82,444,669 (+)NCBI
Rnor_5.0982,205,714 - 82,213,930 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006245280   ⟹   XP_006245342
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8984,179,702 - 84,187,942 (+)NCBI
mRatBN7.2976,731,060 - 76,739,278 (+)NCBI
Rnor_6.0982,436,453 - 82,444,669 (+)NCBI
Rnor_5.0982,205,714 - 82,213,930 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006245281   ⟹   XP_006245343
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8984,179,713 - 84,187,942 (+)NCBI
mRatBN7.2976,731,078 - 76,739,278 (+)NCBI
Rnor_6.0982,436,453 - 82,444,669 (+)NCBI
Rnor_5.0982,205,714 - 82,213,930 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039084218   ⟹   XP_038940146
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8984,179,725 - 84,187,942 (+)NCBI
mRatBN7.2976,731,060 - 76,739,278 (+)NCBI
RefSeq Acc Id: XM_063267754   ⟹   XP_063123824
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8984,179,773 - 84,187,942 (+)NCBI
RefSeq Acc Id: XM_063267755   ⟹   XP_063123825
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8984,179,765 - 84,187,942 (+)NCBI
RefSeq Acc Id: XM_063267756   ⟹   XP_063123826
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8984,179,724 - 84,187,942 (+)NCBI
RefSeq Acc Id: XM_063267757   ⟹   XP_063123827
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8984,179,773 - 84,187,942 (+)NCBI
RefSeq Acc Id: XM_063267758   ⟹   XP_063123828
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8984,179,769 - 84,187,942 (+)NCBI
RefSeq Acc Id: XM_063267759   ⟹   XP_063123829
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8984,179,735 - 84,187,942 (+)NCBI
RefSeq Acc Id: XM_063267761   ⟹   XP_063123831
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8984,179,776 - 84,187,942 (+)NCBI
RefSeq Acc Id: XM_063267762   ⟹   XP_063123832
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8984,179,772 - 84,187,942 (+)NCBI
RefSeq Acc Id: NP_001103011   ⟸   NM_001109541
- Peptide Label: isoform 3
- UniProtKB: D4ABC2 (UniProtKB/TrEMBL),   A6JW05 (UniProtKB/TrEMBL),   A6JW06 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006245342   ⟸   XM_006245280
- Peptide Label: isoform X2
- UniProtKB: A0A8I6A3U5 (UniProtKB/TrEMBL),   A6JW06 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006245343   ⟸   XM_006245281
- Peptide Label: isoform X3
- UniProtKB: A6JW06 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006245341   ⟸   XM_006245279
- Peptide Label: isoform X1
- UniProtKB: A0A8I6A5U2 (UniProtKB/TrEMBL),   A6JW06 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000026467   ⟸   ENSRNOT00000026467
Ensembl Acc Id: ENSRNOP00000074369   ⟸   ENSRNOT00000081958
RefSeq Acc Id: XP_038940146   ⟸   XM_039084218
- Peptide Label: isoform X4
- UniProtKB: A0A8I5ZJ88 (UniProtKB/TrEMBL),   A6JW06 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000076642   ⟸   ENSRNOT00000098165
Ensembl Acc Id: ENSRNOP00000085337   ⟸   ENSRNOT00000095829
Ensembl Acc Id: ENSRNOP00000086434   ⟸   ENSRNOT00000111890
Ensembl Acc Id: ENSRNOP00000092193   ⟸   ENSRNOT00000102574
RefSeq Acc Id: NP_001386045   ⟸   NM_001399116
- Peptide Label: isoform 1
- UniProtKB: A0A8I6A5U2 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001386047   ⟸   NM_001399118
- Peptide Label: isoform 2
- UniProtKB: B2RYA8 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001386044   ⟸   NM_001399115
- Peptide Label: isoform 1
- UniProtKB: A0A8I6A5U2 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001386046   ⟸   NM_001399117
- Peptide Label: isoform 2
- UniProtKB: B2RYA8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063123826   ⟸   XM_063267756
- Peptide Label: isoform X2
- UniProtKB: A0A8I6A3U5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063123829   ⟸   XM_063267759
- Peptide Label: isoform X6
- UniProtKB: B2RYA8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063123825   ⟸   XM_063267755
- Peptide Label: isoform X2
- UniProtKB: A0A8I6A3U5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063123828   ⟸   XM_063267758
- Peptide Label: isoform X5
RefSeq Acc Id: XP_063123832   ⟸   XM_063267762
- Peptide Label: isoform X7
- UniProtKB: A6JW05 (UniProtKB/TrEMBL),   D4ABC2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063123824   ⟸   XM_063267754
- Peptide Label: isoform X1
- UniProtKB: A0A8I6A5U2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063123827   ⟸   XM_063267757
- Peptide Label: isoform X2
- UniProtKB: A0A8I6A3U5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063123831   ⟸   XM_063267761
- Peptide Label: isoform X6
- UniProtKB: B2RYA8 (UniProtKB/TrEMBL)
Protein Domains
J

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-B2RYA8-F1-model_v2 AlphaFold B2RYA8 1-277 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13696776
Promoter ID:EPDNEW_R7300
Type:initiation region
Name:Dnajb2_1
Description:DnaJ heat shock protein family member B2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0982,436,499 - 82,436,559EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1591035 AgrOrtholog
BioCyc Gene G2FUF-27086 BioCyc
Ensembl Genes ENSRNOG00000019506 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000026467.5 UniProtKB/TrEMBL
  ENSRNOT00000081958.2 UniProtKB/TrEMBL
  ENSRNOT00000095829.1 UniProtKB/TrEMBL
  ENSRNOT00000098165.1 UniProtKB/TrEMBL
  ENSRNOT00000102574.1 UniProtKB/TrEMBL
  ENSRNOT00000111890.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.287.110 UniProtKB/TrEMBL
  6.10.140.100 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7930287 IMAGE-MGC_LOAD
InterPro DnaJ_dom_sf UniProtKB/TrEMBL
  DnaJ_domain_CS UniProtKB/TrEMBL
  DnaJ_N UniProtKB/TrEMBL
  DNJB2 UniProtKB/TrEMBL
  Ubiquitin-int_motif UniProtKB/TrEMBL
KEGG Report rno:689593 UniProtKB/TrEMBL
MGC_CLONE MGC:188408 IMAGE-MGC_LOAD
NCBI Gene 689593 ENTREZGENE
PANTHER DNAJ HOMOLOG SUBFAMILY B MEMBER 2 UniProtKB/TrEMBL
  PTHR45168 UniProtKB/TrEMBL
Pfam DnaJ UniProtKB/TrEMBL
PhenoGen Dnajb2 PhenoGen
PRINTS JDOMAIN UniProtKB/TrEMBL
PROSITE DNAJ_1 UniProtKB/TrEMBL
  DNAJ_2 UniProtKB/TrEMBL
  UIM UniProtKB/TrEMBL
RatGTEx ENSRNOG00000019506 RatGTEx
SMART DnaJ UniProtKB/TrEMBL
  UIM UniProtKB/TrEMBL
Superfamily-SCOP DnaJ_N UniProtKB/TrEMBL
UniProt A0A8I5ZJ88 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6A3U5 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6A5U2 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6GJK4_RAT UniProtKB/TrEMBL
  A6JW05 ENTREZGENE, UniProtKB/TrEMBL
  A6JW06 ENTREZGENE, UniProtKB/TrEMBL
  B2RYA8 ENTREZGENE, UniProtKB/TrEMBL
  D4ABC2 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-11-25 Dnajb2  DnaJ heat shock protein family (Hsp40) member B2  Dnajb2  DnaJ (Hsp40) homolog, subfamily B, member 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2010-04-23 Dnajb2  DnaJ (Hsp40) homolog, subfamily B, member 2  LOC689593  similar to DnaJ (Hsp40) homolog, subfamily B, member 10 isoform 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-01-09 LOC689593  similar to DnaJ (Hsp40) homolog, subfamily B, member 10 isoform 2  LOC681650  similar to DnaJ homolog subfamily B member 10 (mDJ8)  Data merged from RGD:1592885 1643240 APPROVED
2006-11-20 LOC689593  similar to DnaJ (Hsp40) homolog, subfamily B, member 10 isoform 2      Symbol and Name status set to provisional 70820 PROVISIONAL
2006-11-20 LOC681650  similar to DnaJ homolog subfamily B member 10 (mDJ8)      Symbol and Name status set to provisional 70820 PROVISIONAL