Dnajb2 (DnaJ heat shock protein family (Hsp40) member B2)

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Gene: Dnajb2 (DnaJ heat shock protein family (Hsp40) member B2) Chinchilla lanigera

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Symbol:

Dnajb2

Name:

DnaJ heat shock protein family (Hsp40) member B2

RGD ID:

8914046

Description:

ENCODES a protein that exhibits ATPase activator activity (ortholog); Hsp70 protein binding (ortholog); polyubiquitin modification-dependent protein binding (ortholog); INVOLVED IN chaperone-mediated protein folding (ortholog); ERAD pathway (ortholog); negative regulation of cell growth (ortholog); ASSOCIATED WITH alacrima, achalasia, and impaired intellectual development syndrome (ortholog); autosomal recessive distal hereditary motor neuronopathy 2 (ortholog); autosomal recessive distal hereditary motor neuronopathy 5 (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); endoplasmic reticulum membrane (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

DnaJ (Hsp40) homolog, subfamily B, member 2; dnaJ homolog subfamily B member 2

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

ChiLan1.0 - Chinchilla ChiLan1.0 Assembly

Position:

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955453	14,148,070 - 14,154,670 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955453	14,147,286 - 14,154,396 (-)	NCBI	ChiLan1.0	ChiLan1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

alacrima, achalasia, and impaired intellectual development syndrome (ISO)

autosomal recessive distal hereditary motor neuronopathy 2 (ISO)

autosomal recessive distal hereditary motor neuronopathy 5 (ISO)

cerebrotendinous xanthomatosis (ISO)

Charcot-Marie-Tooth disease (ISO)

Charcot-Marie-Tooth disease axonal type 2T (ISO)

Charcot-Marie-Tooth disease type 2 (ISO)

Charcot-Marie-Tooth disease X-linked dominant 1 (ISO)

genetic disease (ISO)

myofibrillar myopathy 1 (ISO)

Neurodevelopmental Disorders (ISO)

paroxysmal nonkinesigenic dyskinesia 1 (ISO)

polydactyly (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

chaperone-mediated protein folding (ISO)

ERAD pathway (ISO)

negative regulation of cell growth (ISO)

negative regulation of cell population proliferation (ISO)

negative regulation of inclusion body assembly (ISO)

negative regulation of protein deubiquitination (ISO)

positive regulation of ATP-dependent activity (ISO)

positive regulation of proteasomal ubiquitin-dependent protein catabolic process (ISO)

positive regulation of protein ubiquitination (ISO)

proteasome-mediated ubiquitin-dependent protein catabolic process (ISO)

protein refolding (ISO)

regulation of chaperone-mediated protein folding (ISO)

regulation of protein localization (ISO)

regulation of protein ubiquitination (ISO)

Cellular Component

cytoplasm (ISO)

cytosol (ISO)

endoplasmic reticulum membrane (ISO)

inclusion body (ISO)

nuclear membrane (ISO)

nucleus (ISO)

perinuclear region of cytoplasm (ISO)

proteasome complex (ISO)

Molecular Function

ATPase activator activity (ISO)

Hsp70 protein binding (ISO)

polyubiquitin modification-dependent protein binding (ISO)

proteasome binding (ISO)

protein binding (ISO)

protein serine/threonine kinase binding (ISO)

protein-folding chaperone binding (ISO)

ubiquitin binding (ISO)

ubiquitin protein ligase binding (ISO)

ubiquitin-modified protein reader activity (ISO)

unfolded protein binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Transitive Annotation Pipeline	Automated assignment of GO, PW and RDO ISO annotations across species
2.	OMIM Disease Annotation Pipeline	OMIM Disease Annotation Pipeline

Additional References at PubMed

PMID:30032202

Genomics

Comparative Map Data

Dnajb2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955453	14,148,070 - 14,154,670 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955453	14,147,286 - 14,154,396 (-)	NCBI	ChiLan1.0	ChiLan1.0

DNAJB2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	2	219,279,366 - 219,286,895 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	2	219,279,342 - 219,286,898 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	2	220,144,088 - 220,151,617 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	2	219,852,284 - 219,859,866 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	2	219,969,602 - 219,977,127	NCBI
Celera	2	213,913,742 - 213,921,325 (+)	NCBI		Celera
Cytogenetic Map	2	q35	NCBI
HuRef	2	211,997,126 - 212,004,708 (+)	NCBI		HuRef
CHM1_1	2	220,149,887 - 220,157,470 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	2	219,764,122 - 219,771,651 (+)	NCBI		T2T-CHM13v2.0

Dnajb2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	1	75,213,039 - 75,222,336 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	1	75,213,050 - 75,222,336 (+)	Ensembl		GRCm39 Ensembl
GRCm38	1	75,236,395 - 75,245,692 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	1	75,236,406 - 75,245,692 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	1	75,232,998 - 75,242,267 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	1	75,119,635 - 75,128,838 (+)	NCBI		MGSCv36	mm8
Celera	1	75,727,318 - 75,736,588 (+)	NCBI		Celera
Cytogenetic Map	1	C4	NCBI
cM Map	1	38.64	NCBI

Dnajb2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	9	84,179,702 - 84,187,942 (+)	NCBI		GRCr8
mRatBN7.2	9	76,731,060 - 76,739,278 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	9	76,731,065 - 76,739,277 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	9	85,175,912 - 85,184,076 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	9	90,304,803 - 90,312,970 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	9	88,691,018 - 88,699,186 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	9	82,436,453 - 82,444,669 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	9	82,436,458 - 82,444,668 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	9	82,205,714 - 82,213,930 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	9	74,517,647 - 74,525,857 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	9	74,301,465 - 74,309,675 (+)	NCBI		Celera
Cytogenetic Map	9	q33	NCBI

DNAJB2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	13	121,909,722 - 121,917,299 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	2B	121,924,702 - 121,932,264 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	2B	106,536,846 - 106,544,430 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	2B	225,127,967 - 225,135,556 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	2B	225,127,967 - 225,135,556 (+)	Ensembl	panpan1.1		panPan2

DNAJB2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	37	25,826,496 - 25,834,011 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	37	25,827,713 - 25,833,144 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	37	26,652,500 - 26,659,869 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	37	25,841,856 - 25,849,227 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	37	25,841,844 - 25,849,222 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	37	25,746,217 - 25,753,596 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	37	25,681,582 - 25,688,947 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	37	25,702,255 - 25,709,637 (+)	NCBI		UU_Cfam_GSD_1.0

Dnajb2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405303	175,347,122 - 175,354,398 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936569	1,689,507 - 1,698,954 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936569	1,689,926 - 1,697,179 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

DNAJB2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	15	121,319,982 - 121,335,991 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	15	121,319,897 - 121,335,927 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	15	134,355,341 - 134,363,197 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

DNAJB2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	10	105,185,987 - 105,193,749 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	10	105,186,608 - 105,194,574 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666040	94,203,755 - 94,211,383 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Dnajb2
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624823	5,730,386 - 5,738,459 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624823	5,730,553 - 5,737,668 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_005395542	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_005395545	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_013519969	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_013519970	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AGCD01044858	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	GBCE01074212	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSCLAT00000021418 ⟹ ENSCLAP00000021217

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0 Ensembl	NW_004955453	14,148,070 - 14,154,670 (-)	Ensembl

Ensembl Acc Id:

ENSCLAT00000021419 ⟹ ENSCLAP00000021218

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0 Ensembl	NW_004955453	14,148,153 - 14,154,015 (-)	Ensembl

Ensembl Acc Id:

ENSCLAT00000021420 ⟹ ENSCLAP00000021219

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0 Ensembl	NW_004955453	14,149,159 - 14,154,670 (-)	Ensembl

RefSeq Acc Id:

XM_005395542 ⟹ XP_005395599

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0	NW_004955453	14,147,286 - 14,154,396 (-)	NCBI

Sequence:

show sequence

CGCGTCCTACGCAGCAGTCGCGAGCCAGGGCTGCGGTGCCAGACGGTTCCCGGCGGGGGGCAGG
GGCGGGACTCCTGGCGGAGGAGCCCCGAGGAGGCCTGCTTGACGACTGCCATGGCATCCTACTA
CGAGATTCTAGACGTGCCGCCGAGTGCGTCTGCTGATGACATCAAGAAGGCGTATCGACGAAAG
GCTCTGCAGTGGCACCCAGACAAGAACCCTGATAACAAAGAGTTTGCTGAGAGGAAATTTAAGG
AGGTGGCAGAGGCTTATGAAGTGCTGTCTGACAAGCATAAGCGGGAGATCTACGACCGCTACGG
CCGAGAAGGGCTGACTGGGGCAGGAACCGGCCCCTGTCGGGCAGAAGCTGGTGGTGGTGGTGGG
CCTGGTTTCACCTTCAGCTTCCGCAGCCCTGAGGAAGTCTTCCGGGAGTTCTTTGGCAGTGGAG
ACCCTTTTGCAGAGCTCTTTGATGACTTGGGCCCCTTCTCGGAGCTTCAGAACCGGGGTTCCCG
ACACTCTGGCCCCTTCTTTACCTTCTCCTCCTCCTTTCCTGGGCACTCTGATTTCTCCTCCTCG
TCTTTCTCCTTCAGTCCCGGGGCTGGTGCTTTCCGCTCTGTTTCGACGTCCACCACTTTTGTCC
AGGGACACCGCATCACGACACGCAGAATCATGGAGAATGGGCAGGAGCGAGTGGAAGTGGAGGA
GGACGGGCAGCTGAAGTCAGTTTCAATCAACGGTGTCCCAGATGACCTGGCACTGGGCTTGGAG
CTGAGCCGTCGTGAGCAGCAACAGTCAGTCACCTCCAGGTCGGGAGGTGCACAGATTCGGCAGA
CCCCTGCCCCACGCCCCTCTGACAGCGACCTCTCTGAGGAGGATGAAGACCTGCAGCTTGCCAT
GGCCTACAGCCTGTCAGAGATGGAAGCAGCTGGGCAGAAGCCGGCAGCCTGCCCCAGCTGCAGG
ACTAGGCAGAGATGTGTTCTGAGCTGGATGTCCAGGATGCAGAGTCGCTTCACAGTTCCAACAG
GACAGCACCCTTACCCATGTAATGGGAGGGGACACTCCATTCCTCCCTCACCCATGCTTGAGTG
TAGAGCTGGGGCCTGGGCAGTGGGTGGGGGGCATCAGTAGTCTTAGCCTGTGTACTCTTCCCTG
GGTGTTTGCTGCTGTCTCATGAGGACTACAAGTCCCATAATGCAATGCACCCAGCCAAATTTCT
GATAGGTTACACCCAGGAGAATTGGTGCCTGGTTATGGAGCTGTGTTTCTTGGGATTTGTAGTT
CCAGCCCTGGCCCACCAGTCACTTGCTGTGAATGGGGAGATCTTGTCTTTTGCTTTGTCCCTGG
TGCGGTGGCAAGGATGTGGATGAAGGGGGAATGACCTGAGCCTGGGTTCCCCTGATGCTTCTTG
CTAGCTCCAGGGTTGGAGTGGGCAGGTCAAGACCTTGCAGCATCTGGGAGAAGTCCTCTTCTTC
TGGGCCAGCAGGCAGAGTAGGCAGGGTGTGGCCCTAGAAGGCTGATGGATGTGGGCTGGCACAG
CTTGGAAGGGAAAGCCACCCTTACAGAGGCATGTGGTTGGCACTGGTGTGTGCTGGGAACACGG
GGCATGCTGCTGCTTGAATGGCTTTCTTTGGCCTCTGACCCTGCTGCCTATTCTTTCTTTCCAA
CATCACAGGCAGCTGCCTCTCCTCCTCCCTACCTGGGGAGCCTAAAGCCTGGGAGGGGACTGGT
GGAGGAGGGTGCTGCTAGCCCCTGTAACACTGTGAGTCCCACAGACCTACCAGAGCCAGCCGGG
CTGGGCTCAGACCAAGAGGGAAACTGGAATTCAATAAAACTGAGTTGTGAGAGCTCA

hide sequence

RefSeq Acc Id:

XM_005395545 ⟹ XP_005395602

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0	NW_004955453	14,148,070 - 14,154,396 (-)	NCBI

Sequence:

show sequence

CGCGTCCTACGCAGCAGTCGCGAGCCAGGGCTGCGGTGCCAGACGGTTCCCGGCGGGGGGCAGG
GGCGGGACTCCTGGCGGAGGAGCCCCGAGGAGGCCTGCTTGACGACTGCCATGGCATCCTACTA
CGAGATTCTAGACGTGCCGCCGAGTGCGTCTGCTGATGACATCAAGAAGGCGTATCGACGAAAG
GCTCTGCAGTGGCACCCAGACAAGAACCCTGATAACAAAGAGTTTGCTGAGAGGAAATTTAAGG
AGGTGGCAGAGGCTTATGAAGTGCTGTCTGACAAGCATAAGCGGGAGATCTACGACCGCTACGG
CCGAGAAGGGCTGACTGGGGCAGGAACCGGCCCCTGTCGGGCAGAAGCTGGTGGTGGTGGTGGG
CCTGGTTTCACCTTCAGCTTCCGCAGCCCTGAGGAAGTCTTCCGGGAGTTCTTTGGCAGTGGAG
ACCCTTTTGCAGAGCTCTTTGATGACTTGGGCCCCTTCTCGGAGCTTCAGAACCGGGGTTCCCG
ACACTCTGGCCCCTTCTTTACCTTCTCCTCCTCCTTTCCTGGGCACTCTGATTTCTCCTCCTCG
TCTTTCTCCTTCAGTCCCGGGGCTGGTGCTTTCCGCTCTGTTTCGACGTCCACCACTTTTGTCC
AGGGACACCGCATCACGACACGCAGAATCATGGAGAATGGGCAGGAGCGAGTGGAAGTGGAGGA
GGACGGGCAGCTGAAGTCAGTTTCAATCAACGGTGTCCCAGATGACCTGGCACTGGGCTTGGAG
CTGAGCCGTCGTGAGCAGCAACAGTCAGTCACCTCCAGGTCGGGAGGTGCACAGATTCGGCAGA
CCCCTGCCCCACGCCCCTCTGACAGCGACCTCTCTGAGGAGGATGAAGACCTGCAGCTTGCCAT
GGCCTACAGCCTGTCAGAGATGGAAGCAGCTGGGCAGAAGCCGGCAGATGTGTTCTGAGCTGGA
TGTCCAGGATGCAGAGTCGCTTCACAGTTCCAACAGGACAGCACCCTTACCCATGTAATGGGAG
GGGACACTCCATT

hide sequence

RefSeq Acc Id:

XM_013519969 ⟹ XP_013375423

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0	NW_004955453	14,147,286 - 14,154,396 (-)	NCBI

Sequence:

show sequence

CGCGTCCTACGCAGCAGTCGCGAGCCAGGGCTGCGGTGCCAGACGGTTCCCGGCGGGGGGCAGG
GGCGGGACTCCTGGCGGAGGAGCCCCGAGGAGGCCTGCTTGACGACTGCCATGGCATCCTACTA
CGAGATTCTAGACGTGCCGCCGAGTGCGTCTGCTGATGACATCAAGAAGGCGTATCGACGAAAG
GCTCTGCAGTGGCACCCAGACAAGAACCCTGATAACAAAGAGTTTGCTGAGAGGAAATTTAAGG
AGGTGGCAGAGGCTTATGAAGTGCTGTCTGACAAGCATAAGCGGGAGATCTACGACCGCTACGG
CCGAGAAGGGCTGACTGGGGCAGGAACCGGCCCCTGTCGGGCAGAAGCTGGTGGTGGTGGTGGG
CCTGGTTTCACCTTCAGCTTCCGCAGCCCTGAGGAAGTCTTCCGGGAGTTCTTTGGCAGTGGAG
ACCCTTTTGCAGAGCTCTTTGATGACTTGGGCCCCTTCTCGGAGCTTCAGAACCGGGGTTCCCG
ACACTCTGGCCCCTTCTTTACCTTCTCCTCCTCCTTTCCTGGGCACTCTGATTTCTCCTCCTCG
TCTTTCTCCTTCAGTCCCGGGGCTGGTGCTTTCCGCTCTGTTTCGACGTCCACCACTTTTGTCC
AGGGACACCGCATCACGACACGCAGAATCATGGAGAATGGGCAGGAGCGAGTGGAAGTGGAGGA
GGACGGGCAGCTGAAGTCAGTTTCAATCAACGGTGTCCCAGATGACCTGGCACTGGGCTTGGAG
CTGAGCCGTCGTGAGCAGCAACAGTCAGTCACCTCCAGGTCGGGAGGTGCACAGATTCGGCAGA
CCCCTGCCCCACGCCCCTCTGACAGCGACCTCTCTGAGGAGGATGAAGACCTGCAGCTTGCCAT
GGCCTACAGCCTGTCAGAGATGGAAGCAGCTGGGCAGAAGCCGGCAGCCTGCCCCAGCTGCAGG
ACTAGGCAGAGATGTGTTCTGAGCTGGATGTCCAGGATGCAGAGTCGCTTCACAGTTCCAACAG
GACAGCACCCTTACCCATGCAGCTGCCTCTCCTCCTCCCTACCTGGGGAGCCTAAAGCCTGGGA
GGGGACTGGTGGAGGAGGGTGCTGCTAGCCCCTGTAACACTGTGAGTCCCACAGACCTACCAGA
GCCAGCCGGGCTGGGCTCAGACCAAGAGGGAAACTGGAATTCAATAAAACTGAGTTGTGAGAGC
TCA

hide sequence

RefSeq Acc Id:

XM_013519970 ⟹ XP_013375424

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0	NW_004955453	14,147,286 - 14,154,396 (-)	NCBI

Sequence:

show sequence

CGCGTCCTACGCAGCAGTCGCGAGCCAGGGCTGCGGTGCCAGACGGTTCCCGGCGGGGGGCAGG
GGCGGGACTCCTGGCGGAGGAGCCCCGAGGAGGCCTGCTTGACGACTGCCATGGCATCCTACTA
CGAGATTCTAGACGTGCCGCCGAGTGCGTCTGCTGATGACATCAAGAAGGCGTATCGACGAAAG
GCTCTGCAGTGGCACCCAGACAAGAACCCTGATAACAAAGAGTTTGCTGAGAGGAAATTTAAGG
AGGTGGCAGAGGCTTATGAAGTGCTGTCTGACAAGCATAAGCGGGAGATCTACGACCGCTACGG
CCGAGAAGGGCTGACTGGGGCAGGAACCGGCCCCTGTCGGGCAGAAGCTGGTGGTGGTGGTGGG
CCTGGTTTCACCTTCAGCTTCCGCAGCCCTGAGGAAGTCTTCCGGGAGTTCTTTGGCAGTGGAG
ACCCTTTTGCAGAGCTCTTTGATTTCTCCTCCTCGTCTTTCTCCTTCAGTCCCGGGGCTGGTGC
TTTCCGCTCTGTTTCGACGTCCACCACTTTTGTCCAGGGACACCGCATCACGACACGCAGAATC
ATGGAGAATGGGCAGGAGCGAGTGGAAGTGGAGGAGGACGGGCAGCTGAAGTCAGTTTCAATCA
ACGGTGTCCCAGATGACCTGGCACTGGGCTTGGAGCTGAGCCGTCGTGAGCAGCAACAGTCAGT
CACCTCCAGGTCGGGAGGTGCACAGATTCGGCAGACCCCTGCCCCACGCCCCTCTGACAGCGAC
CTCTCTGAGGAGGATGAAGACCTGCAGCTTGCCATGGCCTACAGCCTGTCAGAGATGGAAGCAG
CTGGGCAGAAGCCGGCAGCCTGCCCCAGCTGCAGGACTAGGCAGAGATGTGTTCTGAGCTGGAT
GTCCAGGATGCAGAGTCGCTTCACAGTTCCAACAGGACAGCACCCTTACCCATGTAATGGGAGG
GGACACTCCATTCCTCCCTCACCCATGCTTGAGTGTAGAGCTGGGGCCTGGGCAGTGGGTGGGG
GGCATCAGTAGTCTTAGCCTGTGTACTCTTCCCTGGGTGTTTGCTGCTGTCTCATGAGGACTAC
AAGTCCCATAATGCAATGCACCCAGCCAAATTTCTGATAGGTTACACCCAGGAGAATTGGTGCC
TGGTTATGGAGCTGTGTTTCTTGGGATTTGTAGTTCCAGCCCTGGCCCACCAGTCACTTGCTGT
GAATGGGGAGATCTTGTCTTTTGCTTTGTCCCTGGTGCGGTGGCAAGGATGTGGATGAAGGGGG
AATGACCTGAGCCTGGGTTCCCCTGATGCTTCTTGCTAGCTCCAGGGTTGGAGTGGGCAGGTCA
AGACCTTGCAGCATCTGGGAGAAGTCCTCTTCTTCTGGGCCAGCAGGCAGAGTAGGCAGGGTGT
GGCCCTAGAAGGCTGATGGATGTGGGCTGGCACAGCTTGGAAGGGAAAGCCACCCTTACAGAGG
CATGTGGTTGGCACTGGTGTGTGCTGGGAACACGGGGCATGCTGCTGCTTGAATGGCTTTCTTT
GGCCTCTGACCCTGCTGCCTATTCTTTCTTTCCAACATCACAGGCAGCTGCCTCTCCTCCTCCC
TACCTGGGGAGCCTAAAGCCTGGGAGGGGACTGGTGGAGGAGGGTGCTGCTAGCCCCTGTAACA
CTGTGAGTCCCACAGACCTACCAGAGCCAGCCGGGCTGGGCTCAGACCAAGAGGGAAACTGGAA
TTCAATAAAACTGAGTTGTGAGAGCTCA

hide sequence

Protein Sequences


Protein RefSeqs	XP_005395599	(Get FASTA)	NCBI Sequence Viewer
	XP_005395602	(Get FASTA)	NCBI Sequence Viewer
	XP_013375423	(Get FASTA)	NCBI Sequence Viewer
	XP_013375424	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCLAP00000021217
	ENSCLAP00000021217.1
	ENSCLAP00000021218.1
	ENSCLAP00000021219.1

RefSeq Acc Id:

XP_005395599 ⟸ XM_005395542

- Peptide Label:

isoform X1

- Sequence:

show sequence

MASYYEILDVPPSASADDIKKAYRRKALQWHPDKNPDNKEFAERKFKEVAEAYEVLSDKHKREI
YDRYGREGLTGAGTGPCRAEAGGGGGPGFTFSFRSPEEVFREFFGSGDPFAELFDDLGPFSELQ
NRGSRHSGPFFTFSSSFPGHSDFSSSSFSFSPGAGAFRSVSTSTTFVQGHRITTRRIMENGQER
VEVEEDGQLKSVSINGVPDDLALGLELSRREQQQSVTSRSGGAQIRQTPAPRPSDSDLSEEDED
LQLAMAYSLSEMEAAGQKPAACPSCRTRQRCVLSWMSRMQSRFTVPTGQHPYPCNGRGHSIPPS
PMLECRAGAWAVGGGHQ

hide sequence

RefSeq Acc Id:	XP_005395602 ⟸ XM_005395545
- Peptide Label:	isoform X4
- UniProtKB:	A0A8C2W0H9 (UniProtKB/TrEMBL), A0A8C2VVD1 (UniProtKB/TrEMBL)
- Sequence:	show sequence MASYYEILDVPPSASADDIKKAYRRKALQWHPDKNPDNKEFAERKFKEVAEAYEVLSDKHKREI YDRYGREGLTGAGTGPCRAEAGGGGGPGFTFSFRSPEEVFREFFGSGDPFAELFDDLGPFSELQ NRGSRHSGPFFTFSSSFPGHSDFSSSSFSFSPGAGAFRSVSTSTTFVQGHRITTRRIMENGQER VEVEEDGQLKSVSINGVPDDLALGLELSRREQQQSVTSRSGGAQIRQTPAPRPSDSDLSEEDED LQLAMAYSLSEMEAAGQKPADVF hide sequence

RefSeq Acc Id:

XP_013375424 ⟸ XM_013519970

- Peptide Label:

isoform X3

- Sequence:

show sequence

MASYYEILDVPPSASADDIKKAYRRKALQWHPDKNPDNKEFAERKFKEVAEAYEVLSDKHKREI
YDRYGREGLTGAGTGPCRAEAGGGGGPGFTFSFRSPEEVFREFFGSGDPFAELFDFSSSSFSFS
PGAGAFRSVSTSTTFVQGHRITTRRIMENGQERVEVEEDGQLKSVSINGVPDDLALGLELSRRE
QQQSVTSRSGGAQIRQTPAPRPSDSDLSEEDEDLQLAMAYSLSEMEAAGQKPAACPSCRTRQRC
VLSWMSRMQSRFTVPTGQHPYPCNGRGHSIPPSPMLECRAGAWAVGGGHQ

hide sequence

RefSeq Acc Id:	XP_013375423 ⟸ XM_013519969
- Peptide Label:	isoform X2
- UniProtKB:	A0A8C2VVC7 (UniProtKB/TrEMBL)
- Sequence:	show sequence MASYYEILDVPPSASADDIKKAYRRKALQWHPDKNPDNKEFAERKFKEVAEAYEVLSDKHKREI YDRYGREGLTGAGTGPCRAEAGGGGGPGFTFSFRSPEEVFREFFGSGDPFAELFDDLGPFSELQ NRGSRHSGPFFTFSSSFPGHSDFSSSSFSFSPGAGAFRSVSTSTTFVQGHRITTRRIMENGQER VEVEEDGQLKSVSINGVPDDLALGLELSRREQQQSVTSRSGGAQIRQTPAPRPSDSDLSEEDED LQLAMAYSLSEMEAAGQKPAACPSCRTRQRCVLSWMSRMQSRFTVPTGQHPYPCSCLSSSLPGE PKAWEGTGGGGCC hide sequence

Ensembl Acc Id:

ENSCLAP00000021218 ⟸ ENSCLAT00000021419

Ensembl Acc Id:

ENSCLAP00000021217 ⟸ ENSCLAT00000021418

Ensembl Acc Id:

ENSCLAP00000021219 ⟸ ENSCLAT00000021420

Protein Domains

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCLAG00000014535	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCLAT00000021418	ENTREZGENE
	ENSCLAT00000021418.1	UniProtKB/TrEMBL
	ENSCLAT00000021419.1	UniProtKB/TrEMBL
	ENSCLAT00000021420.1	UniProtKB/TrEMBL
Gene3D-CATH	1.10.287.110	UniProtKB/TrEMBL
	6.10.140.100	UniProtKB/TrEMBL
InterPro	DnaJ_domain	UniProtKB/TrEMBL
	DnaJ_domain_CS	UniProtKB/TrEMBL
	DNJB2	UniProtKB/TrEMBL
	J_dom_sf	UniProtKB/TrEMBL
	UIM_dom	UniProtKB/TrEMBL
NCBI Gene	Dnajb2	ENTREZGENE
PANTHER	DNAJ HOMOLOG SUBFAMILY B MEMBER 2	UniProtKB/TrEMBL
	PTHR45168	UniProtKB/TrEMBL
Pfam	DnaJ	UniProtKB/TrEMBL
PRINTS	JDOMAIN	UniProtKB/TrEMBL
PROSITE	DNAJ_1	UniProtKB/TrEMBL
	DNAJ_2	UniProtKB/TrEMBL
	UIM	UniProtKB/TrEMBL
SMART	DnaJ	UniProtKB/TrEMBL
	UIM	UniProtKB/TrEMBL
Superfamily-SCOP	SSF46565	UniProtKB/TrEMBL
UniProt	A0A8C2VVC7	ENTREZGENE, UniProtKB/TrEMBL
	A0A8C2VVD1	ENTREZGENE, UniProtKB/TrEMBL
	A0A8C2W0H9	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2016-08-16	Dnajb2	DnaJ heat shock protein family (Hsp40) member B2		DnaJ (Hsp40) homolog, subfamily B, member 2	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - OMIM

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - OMIM