Sgpp2 (sphingosine-1-phosphate phosphatase 2) - Rat Genome Database

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Advanced Search (OLGA)
Gene: Sgpp2 (sphingosine-1-phosphate phosphatase 2) Rattus norvegicus
Analyze
Symbol: Sgpp2
Name: sphingosine-1-phosphate phosphatase 2
RGD ID: 1565739
Description: Predicted to enable sphingosine-1-phosphate phosphatase activity. Predicted to be involved in phospholipid dephosphorylation; regulation of type B pancreatic cell proliferation; and sphingosine metabolic process. Predicted to be located in endoplasmic reticulum. Predicted to be active in endoplasmic reticulum membrane. Orthologous to human SGPP2 (sphingosine-1-phosphate phosphatase 2); PARTICIPATES IN Fabry disease pathway; Gaucher's disease pathway; Krabbe disease pathway; INTERACTS WITH 6-propyl-2-thiouracil; amphetamine; bisphenol A.
Type: protein-coding
RefSeq Status: INFERRED
Previously known as: LOC301543; RGD1565739; similar to Sphingosine-1-phosphate phosphotase 2; sphingosine-1-phosphate phosphotase 2
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8987,211,155 - 87,331,787 (+)NCBIGRCr8
mRatBN7.2979,762,658 - 79,884,665 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl979,763,284 - 79,880,457 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx988,193,174 - 88,310,242 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0993,306,052 - 93,422,660 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0991,704,622 - 91,821,684 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0984,203,094 - 84,321,269 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl984,203,072 - 84,319,874 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0983,961,688 - 84,075,946 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4977,679,320 - 77,799,178 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera977,274,290 - 77,388,812 (+)NCBICelera
Cytogenetic Map9q33NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
17beta-estradiol  (ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
4,4'-sulfonyldiphenol  (ISO)
6-propyl-2-thiouracil  (EXP,ISO)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
amphetamine  (EXP)
aristolochic acid A  (ISO)
benzo[a]pyrene  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
butan-1-ol  (ISO)
cadmium dichloride  (ISO)
cadmium sulfate  (ISO)
carbon nanotube  (ISO)
CGP 52608  (ISO)
chlorpyrifos  (ISO)
cisplatin  (ISO)
DDE  (ISO)
decabromodiphenyl ether  (ISO)
dextran sulfate  (EXP)
Dibutyl phosphate  (ISO)
dibutyl phthalate  (ISO)
diiodine  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
entinostat  (ISO)
formaldehyde  (ISO)
fulvestrant  (ISO)
genistein  (EXP,ISO)
hesperidin  (EXP)
inulin  (ISO)
isobutanol  (ISO)
lead diacetate  (ISO)
lipopolysaccharide  (ISO)
malathion  (ISO)
mercury dibromide  (ISO)
methyl methanesulfonate  (ISO)
mono(2-ethylhexyl) phthalate  (ISO)
N-methyl-4-phenylpyridinium  (ISO)
niclosamide  (ISO)
ozone  (ISO)
p-chloromercuribenzoic acid  (ISO)
panobinostat  (ISO)
paraquat  (EXP)
pentanal  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
propanal  (ISO)
resveratrol  (ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
SB 431542  (ISO)
silicon dioxide  (ISO)
sodium arsenite  (ISO)
sulforaphane  (ISO)
sunitinib  (ISO)
thiram  (ISO)
titanium dioxide  (ISO)
tributylstannane  (ISO)
trichostatin A  (ISO)
triclosan  (ISO)
valproic acid  (ISO)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
3. SMPDB Annotation Import Pipeline Pipeline to import SMPDB annotations from SMPDB into RGD
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12411432   PMID:27059959  


Genomics

Comparative Map Data
Sgpp2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8987,211,155 - 87,331,787 (+)NCBIGRCr8
mRatBN7.2979,762,658 - 79,884,665 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl979,763,284 - 79,880,457 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx988,193,174 - 88,310,242 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0993,306,052 - 93,422,660 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0991,704,622 - 91,821,684 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0984,203,094 - 84,321,269 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl984,203,072 - 84,319,874 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0983,961,688 - 84,075,946 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4977,679,320 - 77,799,178 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera977,274,290 - 77,388,812 (+)NCBICelera
Cytogenetic Map9q33NCBI
SGPP2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382222,423,988 - 222,562,621 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2222,424,543 - 222,562,621 (+)EnsemblGRCh38hg38GRCh38
GRCh372223,288,707 - 223,427,340 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362222,997,566 - 223,131,861 (+)NCBINCBI36Build 36hg18NCBI36
Build 342223,114,826 - 223,249,122NCBI
Celera2217,107,484 - 217,191,808 (+)NCBICelera
Cytogenetic Map2q36.1NCBI
HuRef2215,143,345 - 215,277,358 (+)NCBIHuRef
CHM1_12223,295,733 - 223,430,117 (+)NCBICHM1_1
T2T-CHM13v2.02222,909,191 - 223,047,956 (+)NCBIT2T-CHM13v2.0
Sgpp2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39178,286,186 - 78,396,926 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl178,286,982 - 78,396,926 (+)EnsemblGRCm39 Ensembl
GRCm38178,309,549 - 78,420,289 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl178,310,345 - 78,420,289 (+)EnsemblGRCm38mm10GRCm38
MGSCv37178,306,921 - 78,416,861 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36178,193,492 - 78,303,436 (+)NCBIMGSCv36mm8
Celera178,786,483 - 78,890,682 (+)NCBICelera
Cytogenetic Map1C4NCBI
cM Map140.23NCBI
Sgpp2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545311,242,647 - 11,359,569 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495545311,244,077 - 11,361,990 (-)NCBIChiLan1.0ChiLan1.0
SGPP2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v213125,041,949 - 125,177,133 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12B125,056,920 - 125,192,100 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02B109,668,923 - 109,803,950 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12B228,300,677 - 228,385,137 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B228,300,673 - 228,381,565 (+)Ensemblpanpan1.1panPan2
SGPP2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13728,536,815 - 28,639,380 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3729,372,695 - 29,474,494 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03728,560,624 - 28,662,588 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3728,560,568 - 28,661,255 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13728,472,739 - 28,574,349 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03728,404,302 - 28,505,973 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03728,422,422 - 28,524,202 (+)NCBIUU_Cfam_GSD_1.0
Sgpp2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303178,063,326 - 178,174,545 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365694,406,253 - 4,518,655 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365694,405,804 - 4,518,637 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SGPP2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl15124,318,955 - 124,462,851 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.115124,316,309 - 124,462,855 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.215137,863,888 - 137,960,378 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SGPP2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.110108,339,433 - 108,480,411 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604090,897,357 - 91,035,535 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Sgpp2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248232,638,257 - 2,756,448 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248232,635,128 - 2,756,566 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Sgpp2
819 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:23
Count of miRNA genes:20
Interacting mature miRNAs:22
Transcripts:ENSRNOT00000018882
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
11353957Bmd92Bone mineral density QTL 920.01tibia mineral mass (VT:1000283)volumetric bone mineral density (CMO:0001553)94611419991114199Rat
724547Cm21Cardiac mass QTL 212.7heart mass (VT:0007028)calculated heart weight (CMO:0000073)979271511102910209Rat
61385Edpm9Estrogen-dependent pituitary mass QTL 93.430.05pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)963869687108869687Rat
724544Uae9Urinary albumin excretion QTL 94.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)925268044114175309Rat
1578760Cm53Cardiac mass QTL 533.30.0001heart mass (VT:0007028)heart wet weight (CMO:0000069)956771635101771635Rat
1581580Uae34Urinary albumin excretion QTL 34urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)96207227596470995Rat
12879506Pur33Proteinuria QTL 33urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)94464992189649921Rat
1354626Bvd1Brain ventricular dilatation QTL 13.730.001brain ventricle morphology trait (VT:0000822)hydrocephalus severity score (CMO:0001881)975712843111552878Rat
7794784Mcs31Mammary carcinoma susceptibility QTL 312.98mammary gland integrity trait (VT:0010552)mammary tumor incidence/prevalence measurement (CMO:0000946)977813894111552878Rat
731164Uae25Urinary albumin excretion QTL 253.50.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)925661188100929786Rat
10058949Gmadr5Adrenal mass QTL 520.014adrenal gland mass (VT:0010420)both adrenal glands wet weight to body weight ratio (CMO:0002411)94279151387976209Rat
1578757Pur6Proteinuria QTL 63.30.005urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)96207227596470995Rat
631656Bp108Blood pressure QTL 1085.970.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)94859825193598251Rat
8662828Vetf6Vascular elastic tissue fragility QTL 63.9artery integrity trait (VT:0010639)patent ductus arteriosus score (CMO:0002566)93696235992058970Rat
724515Uae16Urinary albumin excretion QTL 168urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)958163035100929646Rat
731171Glom6Glomerulus QTL 62.80.0003kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)964573531109573531Rat
2303178Bp334Blood pressure QTL 3343.70.01arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)97927151191616855Rat
70186Niddm26Non-insulin dependent diabetes mellitus QTL 263.87blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)92207116986369743Rat
7207814Bmd91Bone mineral density QTL 913.5femur size trait (VT:1000369)femoral neck cross-sectional area (CMO:0001697)92375414483851531Rat
6903941Pur31Proteinuria QTL 310.036urine total protein amount (VT:0000032)urine protein excretion rate (CMO:0000759)94019418885194188Rat
2290450Scl57Serum cholesterol level QTL 574.15blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)93696235995410867Rat
11353949Bp393Blood pressure QTL 393arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)94019418885194188Rat
11353951Bp394Blood pressure QTL 394arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)94464992189649921Rat
10054125Srcrt7Stress Responsive Cort QTL 73.330.0011blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)9187073594Rat
1300134Bp185Blood pressure QTL 1853.73arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)961381434104821652Rat
4889852Pur26Proteinuria QTL 26150.001urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)977813894101597663Rat

Markers in Region
D9Got91  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2979,842,579 - 79,842,704 (+)MAPPERmRatBN7.2
Rnor_6.0984,281,399 - 84,281,523NCBIRnor6.0
Rnor_5.0984,040,284 - 84,040,408UniSTSRnor5.0
RGSC_v3.4977,758,668 - 77,758,793RGDRGSC3.4
RGSC_v3.4977,758,669 - 77,758,793UniSTSRGSC3.4
RGSC_v3.1977,942,088 - 77,942,212RGD
Celera977,353,135 - 77,353,266UniSTS
RH 3.4 Map9730.1UniSTS
RH 3.4 Map9730.1RGD
RH 2.0 Map9819.2RGD
Cytogenetic Map9q33UniSTS
D9Mco89  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2979,833,676 - 79,833,926 (+)MAPPERmRatBN7.2
Rnor_6.0984,272,497 - 84,272,746NCBIRnor6.0
Rnor_5.0984,031,382 - 84,031,631UniSTSRnor5.0
RGSC_v3.4977,749,766 - 77,750,015UniSTSRGSC3.4
Celera977,344,239 - 77,344,488UniSTS
Cytogenetic Map9q33UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 44 105 91 90 59 25 59 6 213 92 85 45 58 31

Sequence


Ensembl Acc Id: ENSRNOT00000018882   ⟹   ENSRNOP00000018882
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl984,203,072 - 84,319,874 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000102924   ⟹   ENSRNOP00000087628
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl979,763,284 - 79,880,457 (+)Ensembl
RefSeq Acc Id: NM_001191811   ⟹   NP_001178740
RefSeq Status: INFERRED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8987,211,864 - 87,328,926 (+)NCBI
mRatBN7.2979,763,394 - 79,880,457 (+)NCBI
Rnor_6.0984,203,094 - 84,317,061 (+)NCBI
Rnor_5.0983,961,688 - 84,075,946 (+)NCBI
Celera977,274,290 - 77,388,812 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039083380   ⟹   XP_038939308
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8987,211,155 - 87,331,787 (+)NCBI
mRatBN7.2979,762,658 - 79,884,665 (+)NCBI
RefSeq Acc Id: XM_039083381   ⟹   XP_038939309
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8987,244,490 - 87,331,787 (+)NCBI
mRatBN7.2979,795,984 - 79,884,665 (+)NCBI
RefSeq Acc Id: XM_039083382   ⟹   XP_038939310
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8987,211,650 - 87,301,311 (+)NCBI
mRatBN7.2979,763,192 - 79,853,934 (+)NCBI
RefSeq Acc Id: XM_063266995   ⟹   XP_063123065
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8987,211,648 - 87,328,448 (+)NCBI
Protein Sequences
Protein RefSeqs NP_001178740 (Get FASTA)   NCBI Sequence Viewer  
  XP_038939308 (Get FASTA)   NCBI Sequence Viewer  
  XP_038939309 (Get FASTA)   NCBI Sequence Viewer  
  XP_038939310 (Get FASTA)   NCBI Sequence Viewer  
  XP_063123065 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000087628.1
RefSeq Acc Id: NP_001178740   ⟸   NM_001191811
- UniProtKB: A0A8I6AGX4 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000018882   ⟸   ENSRNOT00000018882
RefSeq Acc Id: XP_038939308   ⟸   XM_039083380
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038939310   ⟸   XM_039083382
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038939309   ⟸   XM_039083381
- Peptide Label: isoform X1
Ensembl Acc Id: ENSRNOP00000087628   ⟸   ENSRNOT00000102924
RefSeq Acc Id: XP_063123065   ⟸   XM_063266995
- Peptide Label: isoform X2
Protein Domains
Phosphatidic acid phosphatase type 2/haloperoxidase

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-F1LZ44-F1-model_v2 AlphaFold F1LZ44 1-354 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13696787
Promoter ID:EPDNEW_R7311
Type:initiation region
Name:Sgpp2_1
Description:sphingosine-1-phosphate phosphatase 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0984,203,004 - 84,203,064EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1565739 AgrOrtholog
BioCyc Gene G2FUF-27025 BioCyc
BioCyc Pathway PWY3DJ-11470 [sphingosine and sphingosine-1-phosphate metabolism] BioCyc
BioCyc Pathway Image PWY3DJ-11470 BioCyc
Ensembl Genes ENSRNOG00000037695 Ensembl
  ENSRNOG00000069992 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000102924.1 UniProtKB/TrEMBL
Gene3D-CATH Phosphatidic acid phosphatase type 2/haloperoxidase UniProtKB/TrEMBL
InterPro P_Acid_Pase_2/haloperoxi_sf UniProtKB/TrEMBL
  P_Acid_Pase_2/haloperoxidase UniProtKB/TrEMBL
KEGG Report rno:301543 UniProtKB/TrEMBL
NCBI Gene 301543 ENTREZGENE
PANTHER SPHINGOSINE-1-PHOSPHATE PHOSPHATASE 2 UniProtKB/TrEMBL
  SPHINGOSINE-1-PHOSPHATE PHOSPHOHYDROLASE UniProtKB/TrEMBL
Pfam PAP2 UniProtKB/TrEMBL
PhenoGen Sgpp2 PhenoGen
RatGTEx ENSRNOG00000037695 RatGTEx
  ENSRNOG00000069992 RatGTEx
SMART acidPPc UniProtKB/TrEMBL
Superfamily-SCOP SSF48317 UniProtKB/TrEMBL
UniProt A0A8I6AGX4 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2011-08-01 Sgpp2  sphingosine-1-phosphate phosphatase 2  Sgpp2  sphingosine-1-phosphate phosphotase 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-03-07 Sgpp2  sphingosine-1-phosphate phosphotase 2  RGD1565739_predicted  similar to Sphingosine-1-phosphate phosphotase 2 (predicted)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-07 RGD1565739_predicted  similar to Sphingosine-1-phosphate phosphotase 2 (predicted)  LOC301543  similar to Sphingosine-1-phosphate phosphotase 2  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC301543  similar to Sphingosine-1-phosphate phosphotase 2      Symbol and Name status set to provisional 70820 PROVISIONAL