Fyb1 (FYN binding protein 1) - Rat Genome Database

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Gene: Fyb1 (FYN binding protein 1) Rattus norvegicus
Analyze
Symbol: Fyb1
Name: FYN binding protein 1
RGD ID: 1563421
Description: Predicted to enable lipid binding activity. Predicted to be involved in T cell receptor signaling pathway; integrin-mediated signaling pathway; and protein localization to plasma membrane. Predicted to be located in anchoring junction; cytoplasm; and nucleus. Predicted to be part of protein-containing complex. Predicted to be active in plasma membrane. Human ortholog(s) of this gene implicated in thrombocytopenia. Orthologous to human FYB1 (FYN binding protein 1); INTERACTS WITH 17beta-estradiol; 17beta-estradiol 3-benzoate; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: ADAP; Fyb; FYB-120/130; FYN binding protein; FYN binding protein (FYB-120/130); FYN-binding protein; FYN-binding protein 1; LOC499537; p120/p130; RGD1563421; similar to FYN binding protein; SLAP-130; SLP-76-associated phosphoprotein
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8257,360,084 - 57,508,609 (+)NCBIGRCr8
mRatBN7.2255,621,585 - 55,781,206 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl255,632,698 - 55,779,629 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx262,788,995 - 62,878,724 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0260,862,372 - 60,953,666 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0255,864,992 - 55,954,723 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0255,834,904 - 55,983,805 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl255,835,151 - 55,983,804 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0275,576,934 - 75,725,130 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4255,858,764 - 55,950,014 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera251,310,594 - 51,399,297 (+)NCBICelera
Cytogenetic Map2q16NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,1-dichloroethene  (ISO)
17beta-estradiol  (EXP)
17beta-estradiol 3-benzoate  (EXP)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (ISO)
3,4-dichloroaniline  (ISO)
4,4'-diaminodiphenylmethane  (EXP)
acetamide  (EXP)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
alpha-Zearalanol  (EXP)
antirheumatic drug  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenous acid  (ISO)
atrazine  (EXP)
bathocuproine disulfonic acid  (ISO)
benzo[a]pyrene  (ISO)
bisphenol A  (EXP,ISO)
buta-1,3-diene  (ISO)
butanal  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (EXP,ISO)
carbon nanotube  (ISO)
CGP 52608  (ISO)
chloroprene  (ISO)
clothianidin  (ISO)
cobalt dichloride  (ISO)
copper(II) chloride  (ISO)
Cuprizon  (EXP)
diarsenic trioxide  (ISO)
Dibutyl phosphate  (ISO)
diclofenac  (ISO)
diquat  (ISO)
diuron  (ISO)
ethanol  (ISO)
ferric oxide  (ISO)
fonofos  (ISO)
gold atom  (ISO)
gold(0)  (ISO)
ionomycin  (ISO)
irinotecan  (ISO)
isotretinoin  (ISO)
lipopolysaccharide  (ISO)
methotrexate  (ISO)
nickel atom  (ISO)
ozone  (ISO)
paracetamol  (ISO)
parathion  (ISO)
perfluorohexanesulfonic acid  (ISO)
phorbol 13-acetate 12-myristate  (ISO)
pirinixic acid  (ISO)
pyrrolidine dithiocarbamate  (ISO)
silicon dioxide  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
sodium arsenite  (ISO)
tamibarotene  (ISO)
terbufos  (ISO)
testosterone  (EXP)
tetrachloromethane  (ISO)
thapsigargin  (EXP)
thioacetamide  (EXP)
titanium dioxide  (ISO)
trichloroethene  (EXP)
vanadyl sulfate  (ISO)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Targeting of MIST to Src-family kinases via SKAP55-SLAP-130 adaptor complex in mast cells. Fujii Y, etal., FEBS Lett 2003 Apr 10;540(1-3):111-6.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:15153494   PMID:17403904  


Genomics

Comparative Map Data
Fyb1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8257,360,084 - 57,508,609 (+)NCBIGRCr8
mRatBN7.2255,621,585 - 55,781,206 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl255,632,698 - 55,779,629 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx262,788,995 - 62,878,724 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0260,862,372 - 60,953,666 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0255,864,992 - 55,954,723 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0255,834,904 - 55,983,805 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl255,835,151 - 55,983,804 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0275,576,934 - 75,725,130 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4255,858,764 - 55,950,014 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera251,310,594 - 51,399,297 (+)NCBICelera
Cytogenetic Map2q16NCBI
FYB1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38539,105,252 - 39,274,528 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl539,105,252 - 39,274,528 (-)EnsemblGRCh38hg38GRCh38
GRCh37539,105,354 - 39,270,751 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36539,141,114 - 39,255,424 (-)NCBINCBI36Build 36hg18NCBI36
Celera538,991,920 - 39,106,222 (-)NCBICelera
Cytogenetic Map5p13.1NCBI
HuRef539,056,971 - 39,222,025 (-)NCBIHuRef
CHM1_1539,107,349 - 39,272,677 (-)NCBICHM1_1
T2T-CHM13v2.0539,354,788 - 39,524,036 (-)NCBIT2T-CHM13v2.0
Fyb1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39156,552,280 - 6,695,089 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl156,552,334 - 6,692,794 (+)EnsemblGRCm39 Ensembl
GRCm38156,522,796 - 6,665,608 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl156,522,853 - 6,663,313 (+)EnsemblGRCm38mm10GRCm38
MGSCv37156,529,871 - 6,613,312 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36156,527,086 - 6,610,527 (+)NCBIMGSCv36mm8
Celera156,428,716 - 6,511,910 (+)NCBICelera
Cytogenetic Map15A1NCBI
cM Map153.19NCBI
Fyb1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542623,622,004 - 23,717,454 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495542623,621,355 - 23,777,086 (-)NCBIChiLan1.0ChiLan1.0
FYB1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2471,063,022 - 71,231,267 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1569,216,646 - 69,384,905 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0571,100,184 - 71,268,471 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1576,194,420 - 76,307,792 (+)NCBIpanpan1.1PanPan1.1panPan2
FYB1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1469,729,481 - 69,876,962 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl469,729,462 - 69,874,845 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha469,403,032 - 69,553,362 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0470,242,306 - 70,392,973 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl470,245,209 - 70,392,326 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1469,991,531 - 70,141,946 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0470,103,843 - 70,254,571 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0470,643,055 - 70,793,407 (+)NCBIUU_Cfam_GSD_1.0
Fyb1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213228,201,201 - 228,364,092 (-)NCBIHiC_Itri_2
SpeTri2.0NW_0049365183,063,257 - 3,169,469 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FYB1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1624,333,033 - 24,507,740 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11624,332,539 - 24,507,768 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21625,519,895 - 25,621,417 (-)NCBISscrofa10.2Sscrofa10.2susScr3
FYB1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1437,912,771 - 38,078,727 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl437,914,956 - 38,012,623 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607128,282,137 - 28,448,698 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Fyb1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475915,683,779 - 15,793,908 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475915,683,741 - 15,794,628 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Fyb1
634 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:26
Count of miRNA genes:24
Interacting mature miRNAs:26
Transcripts:ENSRNOT00000018634
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
10755430Coatc6Coat color QTL 60.02576coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)21159110056591100Rat
2293671Bss44Bone structure and strength QTL 4410.970.0001lumbar vertebra morphology trait (VT:0010494)lumbar vertebra cortical cross-sectional area (CMO:0001690)243162366148478373Rat
7387318Stl32Serum triglyceride level QTL 323.20.0003blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)22238462767384627Rat
10755436Coatc8Coat color QTL 80.02431coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)23502311780023117Rat
1298074Bp164Blood pressure QTL 1640.003arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)242804607202447032Rat
10755434Coatc7Coat color QTL 70.04794coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)23064806575648065Rat
2293676Bmd19Bone mineral density QTL 1910.70.0001femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)243162366111362592Rat
10755499Bp389Blood pressure QTL 3892.61arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)218960362228801039Rat
2293682Bmd24Bone mineral density QTL 248.90.0001femur mineral mass (VT:0010011)compact volumetric bone mineral density (CMO:0001730)243162366111362592Rat
1358917Cm42Cardiac mass QTL 422.82heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)225413423203928301Rat
731167Glom4Glomerulus QTL 42.40.0082kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)22030467265304672Rat
1358913Cm41Cardiac mass QTL 412.73heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)225413423203928301Rat
152025242Bw191Body weight QTL 1913.62body mass (VT:0001259)238573329122609194Rat
1302794Stl27Serum triglyceride level QTL 274.40.0001blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)225413423143657569Rat
61467Bp14Blood pressure QTL 142.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)243154682202446871Rat
10402051Gdil2Gastrointestinal dilation QTL 2enteric ganglion morphology trait (VT:0001045)length of intestine affected by colonic aganglionosis to total length of colon ratio (CMO:0001836)22490385374786777Rat
9590095Sffal3Serum free fatty acids level QTL 36.780.001blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)22715716072157160Rat
70174BpQTLCluster2Blood pressure QTL cluster 24.24arterial blood pressure trait (VT:2000000)absolute change in mean arterial blood pressure (CMO:0000533)240067944102785628Rat
1358901Cm38Cardiac mass QTL 382heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)225413423157142209Rat
631208Bw1Body weight QTL15.09mesenteric fat pad mass (VT:0010427)mesenteric fat pad weight to body weight ratio (CMO:0000654)24317101783575226Rat
1358899Kidm23Kidney mass QTL 233.88kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)225413423157142209Rat
1358908Bw49Body weight QTL 493.36body mass (VT:0001259)body weight (CMO:0000012)225413652157142078Rat
1300155Bp174Blood pressure QTL 1744.09arterial blood pressure trait (VT:2000000)absolute change in mean arterial blood pressure (CMO:0000533)24280460760653831Rat
2293835Kiddil5Kidney dilation QTL 53.8kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)242804607157142209Rat
1358910Kidm27Kidney mass QTL 275.77kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)225413423157142209Rat
61355Bp36Blood pressure QTL 362.9blood pressure trait (VT:0000183)systolic blood pressure (CMO:0000004)25873687102844969Rat
2300168Bmd47Bone mineral density QTL 476.60.0001femur mineral mass (VT:0010011)bone mineral density (CMO:0001226)22066244865662448Rat
1358911Kidm28Kidney mass QTL 285.42kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)225413423157142209Rat
631266Bp132Blood pressure QTL 1320.0005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)246123260202447032Rat
1358904Cm39Cardiac mass QTL 392.26heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)225413423157142209Rat
1354617Bp240Blood pressure QTL 2404arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)22691781781754745Rat
2293843Kiddil6Kidney dilation QTL 63.1kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)242804607182042367Rat
1357990Ael1Aortic elastin QTL 13.10.00091aorta elastin amount (VT:0003905)aortic elastin21907682564076825Rat
1358887Bw50Body weight QTL 502.39body mass (VT:0001259)body weight (CMO:0000012)225413652157142078Rat
12879863Bp402Blood pressure QTL 4020.003arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)24112578956532139Rat
1354592Rf50Renal function QTL 503.5urine output (VT:0003620)timed urine volume (CMO:0000260)25382274774786777Rat
1298085Bp165Blood pressure QTL 1650.0006arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)242804607202447032Rat
2290453Scl55Serum cholesterol level QTL 552.83blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)226917817136917119Rat
152025206Hrtrt23Heart rate QTL 235.98heart pumping trait (VT:2000009)228484589169504100Rat
1358894Kidm24Kidney mass QTL 244.03kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)225413423157142209Rat
731184Mamtr4Mammary tumor resistance QTL 40.0003mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)21649174061491740Rat
152025204Hrtrt22Heart rate QTL 225.6heart pumping trait (VT:2000009)228484589169504100Rat
61371Edpm1Estrogen-dependent pituitary mass QTL 140.05pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)23513484188029593Rat
1354601Slep1Serum leptin concentration QTL 15.39blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)243171017184114403Rat
1354603Bp243Blood pressure QTL 2433.9arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)226917817127469484Rat

Markers in Region
RH126691  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.0255,961,691 - 55,962,613NCBIRnor6.0
Rnor_5.0275,703,171 - 75,703,938NCBIRnor5.0
RGSC_v3.4255,929,375 - 55,930,840UniSTSRGSC3.4
Celera251,380,085 - 51,381,685UniSTS
Cytogenetic Map2q16UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001109176 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006232019 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008760784 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008760785 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008760786 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008760787 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008760788 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008760789 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039102835 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039102837 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039102839 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063282350 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005500334 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_010063635 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_010063636 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_010063637 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_590914 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide CH474048 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ230924 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ232832 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000002 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000018634   ⟹   ENSRNOP00000018634
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl255,632,698 - 55,779,629 (+)Ensembl
Rnor_6.0 Ensembl255,835,151 - 55,983,804 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000104137   ⟹   ENSRNOP00000083646
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl255,632,698 - 55,779,629 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000113006   ⟹   ENSRNOP00000085597
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl255,689,071 - 55,760,617 (+)Ensembl
RefSeq Acc Id: NM_001109176   ⟹   NP_001102646
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8257,416,476 - 57,506,204 (+)NCBI
mRatBN7.2255,689,071 - 55,778,801 (+)NCBI
Rnor_6.0255,891,542 - 55,981,400 (+)NCBI
Rnor_5.0275,576,934 - 75,725,130 (+)NCBI
RGSC_v3.4255,858,764 - 55,950,014 (+)RGD
Celera251,310,594 - 51,399,297 (+)RGD
Sequence:
RefSeq Acc Id: XM_006232019   ⟹   XP_006232081
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8257,360,084 - 57,508,609 (+)NCBI
mRatBN7.2255,632,700 - 55,781,206 (+)NCBI
Rnor_6.0255,834,906 - 55,983,805 (+)NCBI
Rnor_5.0275,576,934 - 75,725,130 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008760785   ⟹   XP_008759007
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8257,360,084 - 57,508,609 (+)NCBI
mRatBN7.2255,632,700 - 55,781,206 (+)NCBI
Rnor_6.0255,834,904 - 55,979,539 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039102835   ⟹   XP_038958763
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8257,406,029 - 57,508,609 (+)NCBI
mRatBN7.2255,678,602 - 55,781,206 (+)NCBI
RefSeq Acc Id: XM_039102837   ⟹   XP_038958765
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8257,372,438 - 57,508,609 (+)NCBI
mRatBN7.2255,645,030 - 55,781,206 (+)NCBI
RefSeq Acc Id: XM_039102839   ⟹   XP_038958767
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8257,360,084 - 57,508,609 (+)NCBI
mRatBN7.2255,632,700 - 55,781,206 (+)NCBI
RefSeq Acc Id: XM_063282350   ⟹   XP_063138420
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8257,360,084 - 57,485,923 (+)NCBI
RefSeq Acc Id: XR_005500334
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8257,360,084 - 57,508,609 (+)NCBI
mRatBN7.2255,632,700 - 55,781,206 (+)NCBI
RefSeq Acc Id: XR_010063635
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8257,360,084 - 57,508,609 (+)NCBI
RefSeq Acc Id: XR_010063636
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8257,360,084 - 57,508,609 (+)NCBI
RefSeq Acc Id: XR_010063637
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8257,360,084 - 57,508,609 (+)NCBI
RefSeq Acc Id: NP_001102646   ⟸   NM_001109176
- UniProtKB: A6KGF4 (UniProtKB/TrEMBL),   A6KGF5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006232081   ⟸   XM_006232019
- Peptide Label: isoform X1
- UniProtKB: D3ZIE4 (UniProtKB/TrEMBL),   A6KGF5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008759007   ⟸   XM_008760785
- Peptide Label: isoform X2
- UniProtKB: A6KGF5 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000018634   ⟸   ENSRNOT00000018634
RefSeq Acc Id: XP_038958767   ⟸   XM_039102839
- Peptide Label: isoform X4
- UniProtKB: A0A8I6G9A9 (UniProtKB/TrEMBL),   A6KGF5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038958765   ⟸   XM_039102837
- Peptide Label: isoform X3
- UniProtKB: A6KGF4 (UniProtKB/TrEMBL),   A6KGF5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038958763   ⟸   XM_039102835
- Peptide Label: isoform X3
- UniProtKB: A6KGF4 (UniProtKB/TrEMBL),   A6KGF5 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000083646   ⟸   ENSRNOT00000104137
Ensembl Acc Id: ENSRNOP00000085597   ⟸   ENSRNOT00000113006
RefSeq Acc Id: XP_063138420   ⟸   XM_063282350
- Peptide Label: isoform X5
Protein Domains
SH3

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZIE4-F1-model_v2 AlphaFold D3ZIE4 1-830 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13691171
Promoter ID:EPDNEW_R1696
Type:initiation region
Name:Fyb1_1
Description:FYN binding protein 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0255,835,190 - 55,835,250EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1563421 AgrOrtholog
BioCyc Gene G2FUF-54153 BioCyc
Ensembl Genes ENSRNOG00000013886 Ensembl, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSRNOG00055006418 UniProtKB/Swiss-Prot
  ENSRNOG00060024494 UniProtKB/Swiss-Prot
  ENSRNOG00065022066 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000018634.7 UniProtKB/Swiss-Prot
  ENSRNOT00000104137.1 UniProtKB/TrEMBL
  ENSRNOT00000113006.1 UniProtKB/TrEMBL
  ENSRNOT00055010443 UniProtKB/Swiss-Prot
  ENSRNOT00060042527 UniProtKB/Swiss-Prot
  ENSRNOT00065037612 UniProtKB/Swiss-Prot
Gene3D-CATH SH3 Domains UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro FYB1/2-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  FYB_hSH3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  hSH3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SH3-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SH3_domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:499537 UniProtKB/TrEMBL
NCBI Gene 499537 ENTREZGENE
PANTHER PTHR16830 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR16830:SF13 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam hSH3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SH3_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Fyb1 PhenoGen
PROSITE SH3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000013886 RatGTEx
  ENSRNOG00055006418 RatGTEx
  ENSRNOG00060024494 RatGTEx
  ENSRNOG00065022066 RatGTEx
SMART SH3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF50044 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8I6A2N2_RAT UniProtKB/TrEMBL
  A0A8I6G9A9 ENTREZGENE, UniProtKB/TrEMBL
  A6KGF4 ENTREZGENE, UniProtKB/TrEMBL
  A6KGF5 ENTREZGENE, UniProtKB/TrEMBL
  D3ZIE4 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2017-06-12 Fyb1  FYN binding protein 1  Fyb  FYN binding protein  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2011-08-02 Fyb  FYN binding protein  Fyb  FYN binding protein (FYB-120/130)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-09-18 Fyb  FYN binding protein (FYB-120/130)  Fyb  FYN binding protein  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-03-06 Fyb  FYN binding protein  RGD1563421_predicted  similar to FYN binding protein (predicted)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-07 RGD1563421_predicted  similar to FYN binding protein (predicted)  LOC499537  similar to FYN binding protein  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC499537  similar to FYN binding protein      Symbol and Name status set to provisional 70820 PROVISIONAL