Fyb1 (FYN binding protein 1) - Rat Genome Database

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Gene: Fyb1 (FYN binding protein 1) Mus musculus
Analyze
Symbol: Fyb1 (Ensembl: Fyb)
Name: FYN binding protein 1 (Ensembl:FYN binding protein)
RGD ID: 1316290
MGI Page MGI
Description: Predicted to enable lipid binding activity. Acts upstream of or within protein localization to plasma membrane. Located in plasma membrane. Part of protein-containing complex. Is expressed in thymus primordium. Human ortholog(s) of this gene implicated in thrombocytopenia. Orthologous to human FYB1 (FYN binding protein 1).
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: A; ADAP; adhesion and degranulation promoting adaptor protein; B630013F22Rik; Fyb; FYB-120/130; FYN binding protein FYB-130; FYN-binding protein; FYN-binding protein 1; FYN-T-binding protein; p120/130; p120/p130; SLAP-130; SLAP130; SLP-76-associated phosphoprotein
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39156,552,280 - 6,695,089 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl156,552,334 - 6,692,794 (+)EnsemblGRCm39 Ensembl
GRCm38156,522,796 - 6,665,608 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl156,522,853 - 6,663,313 (+)EnsemblGRCm38mm10GRCm38
MGSCv37156,529,871 - 6,613,312 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36156,527,086 - 6,610,527 (+)NCBIMGSCv36mm8
Celera156,428,716 - 6,511,910 (+)NCBICelera
Cytogenetic Map15A1NCBI
cM Map153.19NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,1-dichloroethene  (EXP)
17beta-estradiol  (ISO)
17beta-estradiol 3-benzoate  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (EXP)
3,4-dichloroaniline  (ISO)
4,4'-diaminodiphenylmethane  (ISO)
acetamide  (ISO)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
alpha-Zearalanol  (ISO)
antirheumatic drug  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenous acid  (ISO)
atrazine  (ISO)
bathocuproine disulfonic acid  (ISO)
benzo[a]pyrene  (EXP,ISO)
bisphenol A  (EXP,ISO)
buta-1,3-diene  (EXP)
butanal  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (EXP,ISO)
carbon nanotube  (EXP)
CGP 52608  (ISO)
chloroprene  (EXP)
clothianidin  (ISO)
cobalt dichloride  (ISO)
Cuprizon  (ISO)
diarsenic trioxide  (ISO)
diclofenac  (EXP)
diquat  (EXP)
diuron  (ISO)
ethanol  (EXP)
ferric oxide  (EXP)
fonofos  (ISO)
gold atom  (ISO)
gold(0)  (ISO)
ionomycin  (ISO)
irinotecan  (ISO)
isotretinoin  (ISO)
lipopolysaccharide  (EXP)
methotrexate  (ISO)
nickel atom  (ISO)
ozone  (EXP)
paracetamol  (EXP,ISO)
parathion  (ISO)
perfluorohexanesulfonic acid  (EXP)
phorbol 13-acetate 12-myristate  (ISO)
pirinixic acid  (EXP)
pyrrolidine dithiocarbamate  (ISO)
silicon dioxide  (EXP,ISO)
silver atom  (ISO)
silver(0)  (ISO)
sodium arsenite  (ISO)
tamibarotene  (ISO)
terbufos  (ISO)
testosterone  (ISO)
tetrachloromethane  (EXP)
thapsigargin  (ISO)
thioacetamide  (ISO)
titanium dioxide  (EXP)
trichloroethene  (ISO)
vanadyl sulfate  (ISO)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. MGDs mouse GO annotations MGD data from the GO Consortium
2. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
3. Mouse MP Annotation Import Pipeline RGD automated import pipeline
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:9207119   PMID:10349636   PMID:10469599   PMID:10497204   PMID:10747096   PMID:11042159   PMID:11076861   PMID:11207596   PMID:11217851   PMID:11567140   PMID:11567141   PMID:12176364  
PMID:12477932   PMID:12681493   PMID:14610273   PMID:15153494   PMID:15477347   PMID:15848169   PMID:16020549   PMID:16141072   PMID:16141073   PMID:16709827   PMID:16775024   PMID:16973965  
PMID:16980616   PMID:17003372   PMID:17062627   PMID:17403904   PMID:17478723   PMID:17646386   PMID:17700167   PMID:17785790   PMID:17948263   PMID:18383041   PMID:18802088   PMID:19617540  
PMID:19996090   PMID:20164171   PMID:20661443   PMID:20957749   PMID:21267068   PMID:21525391   PMID:21829440   PMID:21873635   PMID:21881001   PMID:21949020   PMID:22103309   PMID:22117043  
PMID:22291096   PMID:22411628   PMID:22922362   PMID:23407547   PMID:23918975   PMID:24036998   PMID:24101551   PMID:24523237   PMID:24584089   PMID:25455592   PMID:25821220   PMID:25851535  
PMID:25909459   PMID:26320248   PMID:26872694   PMID:27349342   PMID:27354546   PMID:27500644   PMID:27521337   PMID:27605210   PMID:27626380   PMID:29127148   PMID:29950291   PMID:30833485  
PMID:31591574   PMID:31632410   PMID:32038647   PMID:32554809   PMID:33431658   PMID:34659211   PMID:35637282   PMID:38355793  


Genomics

Comparative Map Data
Fyb1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39156,552,280 - 6,695,089 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl156,552,334 - 6,692,794 (+)EnsemblGRCm39 Ensembl
GRCm38156,522,796 - 6,665,608 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl156,522,853 - 6,663,313 (+)EnsemblGRCm38mm10GRCm38
MGSCv37156,529,871 - 6,613,312 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36156,527,086 - 6,610,527 (+)NCBIMGSCv36mm8
Celera156,428,716 - 6,511,910 (+)NCBICelera
Cytogenetic Map15A1NCBI
cM Map153.19NCBI
FYB1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38539,105,252 - 39,274,528 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl539,105,252 - 39,274,528 (-)EnsemblGRCh38hg38GRCh38
GRCh37539,105,354 - 39,270,751 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36539,141,114 - 39,255,424 (-)NCBINCBI36Build 36hg18NCBI36
Celera538,991,920 - 39,106,222 (-)NCBICelera
Cytogenetic Map5p13.1NCBI
HuRef539,056,971 - 39,222,025 (-)NCBIHuRef
CHM1_1539,107,349 - 39,272,677 (-)NCBICHM1_1
T2T-CHM13v2.0539,354,788 - 39,524,036 (-)NCBIT2T-CHM13v2.0
Fyb1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8257,360,084 - 57,508,609 (+)NCBIGRCr8
mRatBN7.2255,621,585 - 55,781,206 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl255,632,698 - 55,779,629 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx262,788,995 - 62,878,724 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0260,862,372 - 60,953,666 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0255,864,992 - 55,954,723 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0255,834,904 - 55,983,805 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl255,835,151 - 55,983,804 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0275,576,934 - 75,725,130 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4255,858,764 - 55,950,014 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera251,310,594 - 51,399,297 (+)NCBICelera
Cytogenetic Map2q16NCBI
Fyb1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542623,622,004 - 23,717,454 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495542623,621,355 - 23,777,086 (-)NCBIChiLan1.0ChiLan1.0
FYB1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2471,063,022 - 71,231,267 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1569,216,646 - 69,384,905 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0571,100,184 - 71,268,471 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1576,194,420 - 76,307,792 (+)NCBIpanpan1.1PanPan1.1panPan2
FYB1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1469,729,481 - 69,876,962 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl469,729,462 - 69,874,845 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha469,403,032 - 69,553,362 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0470,242,306 - 70,392,973 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl470,245,209 - 70,392,326 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1469,991,531 - 70,141,946 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0470,103,843 - 70,254,571 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0470,643,055 - 70,793,407 (+)NCBIUU_Cfam_GSD_1.0
Fyb1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213228,201,201 - 228,364,092 (-)NCBIHiC_Itri_2
SpeTri2.0NW_0049365183,063,257 - 3,169,469 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FYB1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1624,333,033 - 24,507,740 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11624,332,539 - 24,507,768 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21625,519,895 - 25,621,417 (-)NCBISscrofa10.2Sscrofa10.2susScr3
FYB1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1437,912,771 - 38,078,727 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl437,914,956 - 38,012,623 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607128,282,137 - 28,448,698 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Fyb1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475915,683,779 - 15,793,908 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475915,683,741 - 15,794,628 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Fyb1
5028 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:567
Count of miRNA genes:398
Interacting mature miRNAs:458
Transcripts:ENSMUST00000090461, ENSMUST00000159604, ENSMUST00000159714, ENSMUST00000160612, ENSMUST00000161947, ENSMUST00000162154, ENSMUST00000162430, ENSMUST00000163073
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1357459Nhdlq7_mnon-HDL QTL 7 (mouse)Not determined15120489829Mouse
1302121Cliff_mcliff drop aversion (mouse)Not determined15120489829Mouse
1300953Bdt5_mbone density traits 5 (mouse)Not determined15120489829Mouse
5491193Mobq4_mmultigenic obesity QTL 4 (mouse)Not determined15120489829Mouse
1301662Faq8_mfluctuating asymmetry QTL 8 (mouse)Not determined15120489829Mouse
1301023Sluc24_msusceptibility to lung cancer 24 (mouse)Not determined15120489829Mouse
4141541Tglq3_mtriglyceride QTL 3 (mouse)Not determined15120489829Mouse
11062069Bpq31_mblood pressure QTL 31 (mouse)15126273195Mouse
4141446Ffaq4_mfree fatty acid QTL 4 (mouse)Not determined127101390Mouse
1300594Eae2_msusceptibility to experimental allergic encephalomyelitis 2 (mouse)Not determined15131218736Mouse
1301136Pgia8_mproteoglycan induced arthritis 8 (mouse)Not determined15324016724388176Mouse
4141358Ath22_matherosclerosis 22 (mouse)Not determined346465237464652Mouse
10401902Sicd2_mseizure-induced cell death 2 (mouse)Not determined15347438971197538Mouse
4141952W3q7_mweight 3 weeks QTL 7 (mouse)Not determined348969478601286Mouse
4142252Tailaq4_mtail length adjusted QTL 4 (mouse)Not determined348969478601286Mouse
4142448Tailq6_mtail length QTL 6 (mouse)Not determined348969478601286Mouse
1357559Scfq2_msubcutaneous fat pad weight QTL 2 (mouse)Not determined15348969478601286Mouse
1357659Epfpq4_mepididymal fat percentage QTL 4 (mouse)Not determined15348969478601286Mouse
11252136Modvl4_mmodifier of vacuolated lens (mouse)15562049439620614Mouse
26884409Bzwq16_mbi-zygomatic width QTL 16, 16 week (mouse)15612948138000244Mouse
26884384Skwq12_mskull length QTL 12, 16 week (mouse)15612948150763396Mouse
26884387Skwq8_mskull length QTL 8, 10 week (mouse)15612948168271849Mouse
26884412Bzwq10_mbi-zygomatic width QTL 10, 10 week (mouse)15612948171471849Mouse
26884417Bzwq4_mbi-zygomatic width QTL 4, 5 week (mouse)15612948172471849Mouse
27226786Feml11_mfemur length 11, 5 week (mouse)15612948175871849Mouse
27095932Ulnl11_mulna length 11, 16 week (mouse)15612948176384200Mouse
27226717Tibw4_mtibia width 4, proximal, 10 week (mouse)15612948178684200Mouse
27226734Tibmd5_mtibia midshaft diameter 5, 10 week (mouse)15612948186684201Mouse
26884442Sklq6_mskull length QTL 6, 5 week (mouse)156129481100797881Mouse

Markers in Region
PMC152247P1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
MGSCv37X130,588,154 - 130,588,954UniSTSGRCm37
MGSCv37156,603,923 - 6,604,741UniSTSGRCm37
Celera156,502,496 - 6,503,314UniSTS
CeleraX116,929,996 - 116,930,796UniSTS
Cytogenetic Map15A1UniSTS
Cytogenetic MapXE3UniSTS
Cytogenetic Map11DUniSTS
cM Map1155.6UniSTS
UniSTS:224554  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38156,623,067 - 6,623,222UniSTSGRCm38
MGSCv37156,573,067 - 6,573,222UniSTSGRCm37
Celera156,471,657 - 6,471,812UniSTS
Cytogenetic Map15A1UniSTS


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001278269 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_011815 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006519982 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006519983 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006519985 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006519986 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011245328 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011245329 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036159389 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC158901 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC161196 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF001863 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF061744 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK030905 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK037454 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK038161 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK038225 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK046759 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK137907 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK161411 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK172013 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK172164 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC064102 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC141352 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466581 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000090461   ⟹   ENSMUSP00000087947
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl156,609,352 - 6,692,785 (+)Ensembl
GRCm38.p6 Ensembl156,579,871 - 6,663,304 (+)Ensembl
RefSeq Acc Id: ENSMUST00000159604
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl156,675,540 - 6,681,349 (+)Ensembl
GRCm38.p6 Ensembl156,646,059 - 6,651,868 (+)Ensembl
RefSeq Acc Id: ENSMUST00000159714
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl156,609,373 - 6,650,089 (+)Ensembl
GRCm38.p6 Ensembl156,579,892 - 6,620,608 (+)Ensembl
RefSeq Acc Id: ENSMUST00000160612
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl156,614,483 - 6,664,287 (+)Ensembl
GRCm38.p6 Ensembl156,585,002 - 6,634,806 (+)Ensembl
RefSeq Acc Id: ENSMUST00000161947
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl156,689,886 - 6,692,732 (+)Ensembl
GRCm38.p6 Ensembl156,660,405 - 6,663,251 (+)Ensembl
RefSeq Acc Id: ENSMUST00000162154
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl156,683,992 - 6,692,794 (+)Ensembl
GRCm38.p6 Ensembl156,654,511 - 6,663,313 (+)Ensembl
RefSeq Acc Id: ENSMUST00000162430
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl156,649,075 - 6,661,873 (+)Ensembl
GRCm38.p6 Ensembl156,619,594 - 6,632,392 (+)Ensembl
RefSeq Acc Id: ENSMUST00000163073   ⟹   ENSMUSP00000123895
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl156,673,167 - 6,690,357 (+)Ensembl
GRCm38.p6 Ensembl156,643,686 - 6,660,876 (+)Ensembl
RefSeq Acc Id: ENSMUST00000226412   ⟹   ENSMUSP00000154585
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl156,552,334 - 6,609,774 (+)Ensembl
GRCm38.p6 Ensembl156,522,853 - 6,580,293 (+)Ensembl
RefSeq Acc Id: ENSMUST00000227175   ⟹   ENSMUSP00000153970
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl156,599,008 - 6,609,744 (+)Ensembl
GRCm38.p6 Ensembl156,569,527 - 6,580,263 (+)Ensembl
RefSeq Acc Id: NM_001278269   ⟹   NP_001265198
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39156,609,328 - 6,695,089 (+)NCBI
GRCm38156,579,847 - 6,665,608 (+)NCBI
Celera156,428,692 - 6,514,206 (+)NCBI
Sequence:
RefSeq Acc Id: NM_011815   ⟹   NP_035945
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39156,609,328 - 6,695,089 (+)NCBI
GRCm38156,579,847 - 6,665,608 (+)NCBI
MGSCv37156,529,871 - 6,613,312 (+)RGD
Celera156,428,692 - 6,514,206 (+)NCBI
cM Map15 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006519982   ⟹   XP_006520045
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39156,552,281 - 6,695,089 (+)NCBI
GRCm38156,522,797 - 6,665,608 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006519983   ⟹   XP_006520046
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39156,598,918 - 6,695,089 (+)NCBI
GRCm38156,569,445 - 6,665,608 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006519985   ⟹   XP_006520048
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39156,552,281 - 6,695,089 (+)NCBI
GRCm38156,522,797 - 6,665,608 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006519986   ⟹   XP_006520049
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39156,610,534 - 6,695,089 (+)NCBI
GRCm38156,581,053 - 6,665,608 (+)NCBI
Sequence:
RefSeq Acc Id: XM_011245328   ⟹   XP_011243630
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39156,552,280 - 6,695,089 (+)NCBI
GRCm38156,522,796 - 6,665,608 (+)NCBI
Sequence:
RefSeq Acc Id: XM_011245329   ⟹   XP_011243631
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39156,552,280 - 6,695,089 (+)NCBI
GRCm38156,522,796 - 6,665,608 (+)NCBI
Sequence:
RefSeq Acc Id: XM_036159389   ⟹   XP_036015282
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39156,552,281 - 6,681,357 (+)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: NP_035945   ⟸   NM_011815
- Peptide Label: isoform 1
- UniProtKB: Q9Z2H3 (UniProtKB/Swiss-Prot),   O35601 (UniProtKB/Swiss-Prot),   B2RUR0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001265198   ⟸   NM_001278269
- Peptide Label: isoform 2
- UniProtKB: O35601 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006520045   ⟸   XM_006519982
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_006520048   ⟸   XM_006519985
- Peptide Label: isoform X5
- Sequence:
RefSeq Acc Id: XP_006520046   ⟸   XM_006519983
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_006520049   ⟸   XM_006519986
- Peptide Label: isoform X7
- Sequence:
RefSeq Acc Id: XP_011243630   ⟸   XM_011245328
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_011243631   ⟸   XM_011245329
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: ENSMUSP00000087947   ⟸   ENSMUST00000090461
RefSeq Acc Id: ENSMUSP00000123895   ⟸   ENSMUST00000163073
RefSeq Acc Id: ENSMUSP00000153970   ⟸   ENSMUST00000227175
RefSeq Acc Id: ENSMUSP00000154585   ⟸   ENSMUST00000226412
RefSeq Acc Id: XP_036015282   ⟸   XM_036159389
- Peptide Label: isoform X6
Protein Domains
SH3

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-O35601-F1-model_v2 AlphaFold O35601 1-819 view protein structure

Promoters
RGD ID:6847184
Promoter ID:MM_ACW:17329
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour
Transcripts:FYBANDEG665511.DSEP07
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36156,519,596 - 6,520,096 (+)MPROMDB
RGD ID:6826019
Promoter ID:MM_KWN:17958
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Lung
Transcripts:ENSMUST00000090461,   ENSMUST00000110659,   UC007VDI.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36156,529,266 - 6,530,967 (+)MPROMDB
RGD ID:8683344
Promoter ID:EPDNEW_M19702
Type:initiation region
Name:Fyb_1
Description:Mus musculus FYN binding protein , transcript variant 2, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M19704  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38156,579,893 - 6,579,953EPDNEW
RGD ID:8683348
Promoter ID:EPDNEW_M19704
Type:multiple initiation site
Name:Fyb_2
Description:Mus musculus FYN binding protein , transcript variant 2, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M19702  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38156,654,468 - 6,654,528EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1346327 AgrOrtholog
Ensembl Genes ENSMUSG00000022148 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000090461 ENTREZGENE
  ENSMUST00000090461.12 UniProtKB/Swiss-Prot
  ENSMUST00000163073.2 UniProtKB/TrEMBL
  ENSMUST00000226412.2 UniProtKB/TrEMBL
  ENSMUST00000227175.2 UniProtKB/TrEMBL
Gene3D-CATH SH3 Domains UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro FYB1/2-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  FYB_hSH3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  hSH3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SH3-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SH3_domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:23880 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:1346327 ENTREZGENE
NCBI Gene 23880 ENTREZGENE
PANTHER PTHR16830 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR16830:SF13 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam hSH3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SH3_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Fyb1 PhenoGen
PROSITE SH3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART SH3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF50044 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A2I3BPY6_MOUSE UniProtKB/TrEMBL
  A0A2I3BRH1_MOUSE UniProtKB/TrEMBL
  B2RUR0 ENTREZGENE, UniProtKB/TrEMBL
  F6V072_MOUSE UniProtKB/TrEMBL
  FYB1_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
  Q3TA12_MOUSE UniProtKB/TrEMBL
  Q8CAX4_MOUSE UniProtKB/TrEMBL
  Q9Z2H3 ENTREZGENE
UniProt Secondary Q9Z2H3 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-09-25 Fyb1  FYN binding protein 1  Fyb  FYN binding protein  Symbol and/or name updated 27372883 PROVISIONAL