Fam220a (family with sequence similarity 220, member A)

Gene: Fam220a (family with sequence similarity 220, member A) Rattus norvegicus

Analyze

Symbol:

Fam220a

Name:

family with sequence similarity 220, member A

RGD ID:

1561923

Description:

Predicted to enable STAT family protein binding activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II. Predicted to be located in acrosomal vesicle. Predicted to be active in nucleus. Orthologous to several human genes including FAM220A (family with sequence similarity 220 member A); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3,3',4,4',5-pentachlorobiphenyl; acrylamide.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

LOC498145; similar to RIKEN cDNA 2810453I06; Sipar; STAT3-interacting protein as a repressor

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	12	16,111,593 - 16,127,584 (-)	NCBI		GRCr8
mRatBN7.2	12	10,997,969 - 11,013,962 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	12	10,997,740 - 11,016,501 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	12	11,805,254 - 11,821,251 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	12	12,428,542 - 12,444,538 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	12	11,453,553 - 11,469,566 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	12	13,043,038 - 13,067,043 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	12	13,043,038 - 13,067,341 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	12	15,088,130 - 15,110,348 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	12	11,341,686 - 11,343,288 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	12	12,792,738 - 12,808,579 (-)	NCBI		Celera
Cytogenetic Map	12	p11	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(1->4)-beta-D-glucan (ISO)

1,2-dimethylhydrazine (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP)

2-hydroxypropanoic acid (ISO)

3,3',4,4',5-pentachlorobiphenyl (EXP)

acrylamide (EXP)

antirheumatic drug (ISO)

arsenite(3-) (ISO)

bisphenol A (EXP,ISO)

carbon nanotube (ISO)

chlorpyrifos (ISO)

cisplatin (ISO)

copper(II) sulfate (ISO)

Cuprizon (EXP)

cyclosporin A (ISO)

dibenzo[a,l]pyrene (ISO)

Dibutyl phosphate (ISO)

doxorubicin (ISO)

endosulfan (EXP)

folic acid (ISO)

N-methyl-4-phenylpyridinium (EXP)

ozone (ISO)

paracetamol (EXP,ISO)

pentachlorophenol (ISO)

perfluorooctane-1-sulfonic acid (ISO)

rac-lactic acid (ISO)

rotenone (ISO)

sunitinib (ISO)

temozolomide (ISO)

thioacetamide (EXP)

titanium dioxide (ISO)

trichloroethene (EXP)

urethane (ISO)

valproic acid (ISO)

zinc atom (ISO)

zinc(0) (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

negative regulation of transcription by RNA polymerase II (IBA,ISO)

Cellular Component

acrosomal vesicle (ISS)

nucleus (IBA,ISO)

Molecular Function

protein binding (ISO)

STAT family protein binding (IBA,ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
3.	Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.	Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.

Additional References at PubMed

PMID:25943107	PMID:26026268

Genomics

Comparative Map Data

Fam220a
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	12	16,111,593 - 16,127,584 (-)	NCBI		GRCr8
mRatBN7.2	12	10,997,969 - 11,013,962 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	12	10,997,740 - 11,016,501 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	12	11,805,254 - 11,821,251 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	12	12,428,542 - 12,444,538 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	12	11,453,553 - 11,469,566 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	12	13,043,038 - 13,067,043 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	12	13,043,038 - 13,067,341 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	12	15,088,130 - 15,110,348 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	12	11,341,686 - 11,343,288 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	12	12,792,738 - 12,808,579 (-)	NCBI		Celera
Cytogenetic Map	12	p11	NCBI

FAM220A
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	7	6,329,411 - 6,348,967 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	7	6,329,411 - 6,348,981 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	7	6,369,042 - 6,388,598 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	7	6,335,565 - 6,355,115 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	7	6,346,541 - 6,366,073 (+)	NCBI		Celera
Cytogenetic Map	7	p22.1	NCBI
HuRef	7	6,240,692 - 6,260,128 (-)	NCBI		HuRef
CHM1_1	7	6,368,638 - 6,388,157 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	7	6,448,805 - 6,468,359 (-)	NCBI		T2T-CHM13v2.0
CRA_TCAGchr7v2	7	6,415,393 - 6,434,949 (-)	NCBI

Fam220a
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	5	143,534,475 - 143,550,286 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	5	143,534,461 - 143,550,286 (+)	Ensembl		GRCm39 Ensembl
GRCm39 Ensembl	5	143,534,463 - 143,550,286 (+)	Ensembl		GRCm39 Ensembl
GRCm38	5	143,548,720 - 143,564,531 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	5	143,548,708 - 143,564,531 (+)	Ensembl	GRCm38		mm10	GRCm38
GRCm38.p6 Ensembl	5	143,548,706 - 143,564,531 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	5	144,309,574 - 144,325,393 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	5	143,804,343 - 143,820,144 (+)	NCBI		MGSCv36	mm8
Celera	5	140,595,338 - 140,611,144 (+)	NCBI		Celera
Cytogenetic Map	5	G2	NCBI
cM Map	5	82.27	NCBI

Fam220a
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0	NW_004955460	13,329,417 - 13,335,986 (+)	NCBI	ChiLan1.0	ChiLan1.0

LOC100683001
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	6	11,692,532 - 11,711,505 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
Dog10K_Boxer_Tasha	6	13,317,709 - 13,336,687 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	6	11,693,112 - 11,712,092 (-)	NCBI		ROS_Cfam_1.0
UMICH_Zoey_3.1	6	11,569,420 - 11,588,404 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	6	11,548,525 - 11,567,497 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	6	11,775,631 - 11,795,213 (-)	NCBI		UU_Cfam_GSD_1.0

Fam220a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024409344	139,778,284 - 139,792,475 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936750	165,233 - 166,026 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936750	152,866 - 166,982 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

LOC110260073
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1	3	4,821,544 - 4,848,691 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1

FAM220A
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	28	15,538,085 - 15,560,278 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	28	15,539,047 - 15,539,826 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666102	516,560 - 537,110 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Fam220a
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624740	31,009,409 - 31,010,170 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Fam220a
133 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	138
Count of miRNA genes:	114
Interacting mature miRNAs:	123
Transcripts:	ENSRNOT00000029692
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
2312418	Kidm41	Kidney mass QTL 41	3.7	0.0001	kidney mass (VT:0002707)	single kidney wet weight to body weight ratio (CMO:0000622)	12	1	19611090	Rat
10755457	Coatc14	Coat color QTL 14		0.01759	coat/hair pigmentation trait (VT:0010463)	pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)	12	1	22591684	Rat
6893681	Bw109	Body weight QTL 109	2.3	0.004	body mass (VT:0001259)	body weight (CMO:0000012)	12	1	23297788	Rat
1581516	Cm56	Cardiac mass QTL 56	4.2	0.05	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	12	1	29333307	Rat
1598855	Bp294	Blood pressure QTL 294	3.5		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	12	1	34851688	Rat
7411660	Foco28	Food consumption QTL 28	10.9	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	12	1	42110980	Rat
9590086	Insglur6	Insulin/glucose ratio QTL 6	18.97	0.001	blood insulin amount (VT:0001560)	calculated plasma insulin level (CMO:0002170)	12	1	42110980	Rat
8694179	Bw150	Body weight QTL 150	2.9	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	12	1	42110980	Rat
7411586	Foco5	Food consumption QTL 5	5.4	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	12	1	42110980	Rat
7411595	Foco9	Food consumption QTL 9	4	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	12	1	42110980	Rat
7411545	Bw128	Body weight QTL 128	5.2	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	12	1	42110980	Rat
9590147	Scort7	Serum corticosterone level QTL 7	13.61	0.001	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	12	1	42110980	Rat
2303575	Insul14	Insulin level QTL 14	4		blood insulin amount (VT:0001560)	blood insulin level (CMO:0000349)	12	1	42450532	Rat
737979	Pia22	Pristane induced arthritis QTL 22	53.1		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	12	1	44465750	Rat
634351	Apr5	Acute phase response QTL 5	6.7		blood interleukin-6 amount (VT:0008595)	plasma interleukin-6 level (CMO:0001927)	12	1	44503507	Rat
2302042	Pia38	Pristane induced arthritis QTL 38	3.5	0.001	blood immunoglobulin amount (VT:0002460)	serum immunoglobulin G1 level (CMO:0002115)	12	1	44503507	Rat
634350	Apr4	Acute phase response QTL 4	6		orosomucoid 1 amount (VT:0010541)	plasma orosomucoid 1 level (CMO:0001467)	12	1172005	46172005	Rat
8552918	Pigfal7	Plasma insulin-like growth factor 1 level QTL 7			blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	12	5564495	46669029	Rat
7411547	Bw129	Body weight QTL 129		0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	6	5564495	46669029	Rat
7411597	Foco10	Food consumption QTL 10		0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	12	5564495	46669029	Rat
7411641	Foco19	Food consumption QTL 19	27.7	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	12	5564495	46669029	Rat
8552964	Pigfal17	Plasma insulin-like growth factor 1 level QTL 17	3.5		blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	12	5564495	46669029	Rat
7411588	Foco6	Food consumption QTL 6		0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	12	5564495	46669029	Rat
8552912	Pigfal6	Plasma insulin-like growth factor 1 level QTL 6	5		blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	12	5564498	46669029	Rat
10059594	Kidm46	Kidney mass QTL 46	3.79	0.025	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	12	6107579	46669029	Rat
1600391	Edcs2	Endometrial carcinoma susceptibility QTL2	3.5	0.01	uterus morphology trait (VT:0001120)	percentage of study population developing endometrioid carcinoma during a period of time (CMO:0001759)	12	6833190	17870186	Rat
1302792	Scl21	Serum cholesterol level QTL 21	3.8	0.0011	blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	12	7196730	46669029	Rat
2293086	Iddm30	Insulin dependent diabetes mellitus QTL 30	3.82		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	12	8449490	28302290	Rat
61331	Eau2	Experimental allergic uveoretinitis QTL 2		0.0005	uvea integrity trait (VT:0010551)	experimental autoimmune uveitis score (CMO:0001504)	12	8525423	28064601	Rat
1331739	Hrtrt14	Heart rate QTL 14	3.56232		heart pumping trait (VT:2000009)	heart rate (CMO:0000002)	12	9318216	12829686	Rat
1300157	Rf21	Renal function QTL 21	4.4		renal blood flow trait (VT:2000006)	absolute change in renal blood flow rate (CMO:0001168)	12	9318216	32103380	Rat
1549829	Scl48	Serum cholesterol level QTL 48	5		blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	12	9603277	46669029	Rat
2293699	Bss49	Bone structure and strength QTL 49	5.61	0.0001	lumbar vertebra size trait (VT:0010518)	lumbar vertebra trabecular cross-sectional area (CMO:0001692)	12	10474137	46669029	Rat
2300186	Bmd59	Bone mineral density QTL 59	7.1	0.0001	lumbar vertebra mineral mass (VT:0010511)	volumetric bone mineral density (CMO:0001553)	12	10474137	46669029	Rat

Markers in Region

RH134487

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	12	10,997,907 - 10,998,097 (+)	MAPPER	mRatBN7.2
Rnor_6.0	12	13,042,977 - 13,043,165	NCBI	Rnor6.0
Rnor_5.0	12	15,088,069 - 15,088,257	UniSTS	Rnor5.0
RGSC_v3.4	12	11,341,625 - 11,341,813	UniSTS	RGSC3.4
Celera	12	12,792,675 - 12,792,865	UniSTS
Cytogenetic Map	12	p11	UniSTS

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium	2	37	14	14	11	14	8	11	74	20	40	11	8
Low	1	6	43	27	8	27				15	1
Below cutoff

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001017485	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	BC076392	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH474012	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000012	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSRNOT00000029692 ⟹ ENSRNOP00000059765

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	12	10,997,807 - 11,000,259 (-)	Ensembl
Rnor_6.0 Ensembl	12	13,043,038 - 13,067,341 (-)	Ensembl

RefSeq Acc Id:

ENSRNOT00000102797 ⟹ ENSRNOP00000078852

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	12	10,997,740 - 11,016,501 (-)	Ensembl

RefSeq Acc Id:

NM_001017485 ⟹ NP_001017485

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	12	16,111,593 - 16,127,584 (-)	NCBI
mRatBN7.2	12	10,997,969 - 11,013,962 (-)	NCBI
Rnor_6.0	12	13,043,038 - 13,067,043 (-)	NCBI
Rnor_5.0	12	15,088,130 - 15,110,348 (-)	NCBI
RGSC_v3.4	12	11,341,686 - 11,343,288 (-)	RGD
Celera	12	12,792,738 - 12,808,579 (-)	RGD

Sequence:

show sequence

GCAAGGGGCTGACCCGTACGCTGCTCATCTTCTTTGACTTGGCTTGGCGGCTGCGCATCAACTT
TCCCTACCTCTACATCGTAGCTTCCATGATGCTCAACGTGCGCCTGCAGGTTCATATTGAGATC
CACTGAAGGCCATCCTTGACCGATAGGCATCACCCCGGACTCGCTGCACCAGAGGGCGCAAAGC
ATGAGGGCTGGGAGAGGGACCCTGGGTGTTTGCCTGGCCAGTGTGAAGCAGTCACAAGGAGGTG
ACCTGGACAAACTAGCATGTGGCCTTAAGAGAAGAAGTGAGAAGAGGAACCCTAGCCCCTCAGA
TGTGCCTTCTTGGACAGACCAGCCTGTAGCAGACACCCATGGAAAGTCACGGGCCATGGCGGCA
GCGTCCTCGGAAATGAAGCGTGATCAGAGCAAGGCCAGCCTCATACTTCACAGCGGCTTCAAAG
CGCTTCAGTATCTGAAGGAGTCAATGGGGAGAAATTCAACTCCAGCAGCCTCCCTAAGCATGGC
TGTGGTTCTGTCCTCTGCTCCTTCAGAAGAACATGGAGCTGGGGTGTCCGGTGGCATCGGGGAT
ACACTAGGAAGTGACTGGCCAGCAAGAGAGCCCAGAACCACCGATAGCTGTGGACAGTACCTCA
AAGGAGAGGCCTGGGTGTCAGGATGGCAAGGCCATCCAAAAGTGAGGGAAGTGGGATTCCTAAG
AGGTGAACCCCTAAGTGCTGTCCCCAAGGGGCTAGGCACCAGATCAGAACTGTCTTACTGCTCT
GAGCTGTGCCAGCTGCCATACACTTACCCCTATTATGAAGCTCTCCCAGAGGACAAGACGAGAT
GTGTGTCCCTTGACCACTTAAGTCCCGTGTTTTCAGAGGAAACAGTAGAAGATGAGAAAACTCT
CTCAAGTACGTCAGATGGTCTGCAGATAGTCATGGGGTTACTGGCTCTGCAATCTTCCAGATTA
ACAAGTCTCTGATGCCATAGTTCAGGTACAAGCAGAACAATAAAAATAGCAAATTAATTTTAAA
GGGTGTCTTACAGTTTCTTTTGCATTAAGTCCGGCGTTCGCTGCAGCTGTTCAGTTCCTGCTCT
GATTGCTGAGACCGACCAGACACACCTCGATGGTTGATGCAGAGGGACATTTTCGAGCATGGTT
TCAGTCTTTCTGGAAAGACGCCCCAAACTGGGAAACCCTCTCCCCTGGGGAAATGATCGATCTA
CCCCCGTATAAGATCAGACAGGAACGAACCATTTAGCACCGAGTTCGATATTATGGAGACCCAT
TCTCAAGGGCTAGCATCCTCAGCCTCCTGCCTCAGCTCACCTTGACCGTCTGACGGAAGTGCCG
GTCTGTAGGCTGTGCCGTCCACTTCTTGTAAGCTGTACTTGGGTCATGAAGAGTCTTGTCACTT
CGGCATTGCACAGACTCTGACCTGCAGCCAGATGTCCCTTCTCACATGCTCCTCAGCTCCTGCC
TGAGTTGGAGTTTGTAATGGAGAAGTTGCAATATTAAATTTAGGATAATTTTAAATTACAGAAG
AGTTTGAGATTTTTCTGCGGACAGAACATAGATCGCAAATGAAGTATTTTCCTTTACCCAGACC
CAGGACTTGTGATTTCTTTTACATTAAGACCCCCCCCCCCCTCCGCCCAAGTAACTCTCCCTTT
GTGGTTTGTTGATAACTTTAATAAAGGTCACTGAATGAGTGGACATTTTAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAA

hide sequence

Protein Sequences


Protein RefSeqs	NP_001017485	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH76392	(Get FASTA)	NCBI Sequence Viewer
	EDL89662	(Get FASTA)	NCBI Sequence Viewer
	EDL89663	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000059765.1
	ENSRNOP00000078852
	ENSRNOP00000078852.1
	ENSRNOP00065000167
	ENSRNOP00065000168
GenBank Protein	Q6DGF6	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_001017485 ⟸ NM_001017485

- UniProtKB:

Q6DGF6 (UniProtKB/Swiss-Prot), A6K1K4 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MRAGRGTLGVCLASVKQSQGGDLDKLACGLKRRSEKRNPSPSDVPSWTDQPVADTHGKSRAMAA
ASSEMKRDQSKASLILHSGFKALQYLKESMGRNSTPAASLSMAVVLSSAPSEEHGAGVSGGIGD
TLGSDWPAREPRTTDSCGQYLKGEAWVSGWQGHPKVREVGFLRGEPLSAVPKGLGTRSELSYCS
ELCQLPYTYPYYEALPEDKTRCVSLDHLSPVFSEETVEDEKTLSSTSDGLQIVMGLLALQSSRL
TSL

hide sequence

RefSeq Acc Id:

ENSRNOP00000059765 ⟸ ENSRNOT00000029692

RefSeq Acc Id:

ENSRNOP00000078852 ⟸ ENSRNOT00000102797

Protein Domains

SIPAR

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q6DGF6-F1-model_v2	AlphaFold	Q6DGF6	1-259	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13698436

Promoter ID:

EPDNEW_R8961

Type:

initiation region

Name:

Fam220a_1

Description:

family with sequence similarity 220, member A

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	12	13,067,349 - 13,067,409	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1561923	AgrOrtholog
BioCyc Gene	G2FUF-20009	BioCyc
Ensembl Genes	ENSRNOG00000024605	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
	ENSRNOG00065000102	UniProtKB/Swiss-Prot
Ensembl Transcript	ENSRNOT00000029692.7	UniProtKB/Swiss-Prot
	ENSRNOT00000102797	ENTREZGENE
	ENSRNOT00000102797.1	UniProtKB/Swiss-Prot
	ENSRNOT00065000168	UniProtKB/Swiss-Prot
	ENSRNOT00065000169	UniProtKB/Swiss-Prot
IMAGE_CLONE	IMAGE:7107018	IMAGE-MGC_LOAD
InterPro	FAM220A	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	SIPAR	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	rno:498145	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGC_CLONE	MGC:94793	IMAGE-MGC_LOAD
NCBI Gene	498145	ENTREZGENE
PANTHER	PROTEIN FAM220A	UniProtKB/Swiss-Prot
	PROTEIN FAM220A	UniProtKB/TrEMBL
	PROTEIN FAM220A	UniProtKB/TrEMBL
	PTHR31980	UniProtKB/Swiss-Prot
Pfam	FAM220	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen	Fam220a	PhenoGen
RatGTEx	ENSRNOG00000024605	RatGTEx
	ENSRNOG00065000102	RatGTEx
UniProt	A6K1K4	ENTREZGENE, UniProtKB/TrEMBL
	F220A_RAT	UniProtKB/Swiss-Prot, ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2012-09-18	Fam220a	family with sequence similarity 220, member A	LOC498145	similar to RIKEN cDNA 2810453I06	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2006-02-09	LOC498145	similar to RIKEN cDNA 2810453I06			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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