Tdp2 (tyrosyl-DNA phosphodiesterase 2) - Rat Genome Database

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Gene: Tdp2 (tyrosyl-DNA phosphodiesterase 2) Rattus norvegicus
Analyze
Symbol: Tdp2
Name: tyrosyl-DNA phosphodiesterase 2
RGD ID: 1560342
Description: Predicted to enable metal ion binding activity; phosphoric diester hydrolase activity; and single-stranded DNA binding activity. Predicted to be involved in double-strand break repair and neuron development. Predicted to be located in aggresome and nuclear body. Predicted to be active in PML body and cytoplasm. Human ortholog(s) of this gene implicated in autosomal recessive spinocerebellar ataxia 23. Orthologous to human TDP2 (tyrosyl-DNA phosphodiesterase 2); INTERACTS WITH azoxystrobin; bisphenol A; chlorpyrifos.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: 5'-Tyr-DNA phosphodiesterase; 5'-tyrosyl-DNA phosphodiesterase; LOC498749; MGC124734; similar to putative TRAF and TNF receptor associated protein; Traf and Tnf receptor associated protein; TRAF and TNF receptor-associated protein; Ttrap; tyr-DNA phosphodiesterase 2
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81740,656,969 - 40,668,362 (-)NCBIGRCr8
mRatBN7.21740,228,943 - 40,240,337 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1740,228,947 - 40,240,313 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1740,297,128 - 40,308,451 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01741,901,173 - 41,912,496 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01740,184,268 - 40,195,590 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01742,229,667 - 42,241,025 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1742,229,642 - 42,241,066 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01744,097,466 - 44,108,824 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41747,290,530 - 47,301,849 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1739,866,248 - 39,877,568 (-)NCBICelera
Cytogenetic Map17p11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
double-strand break repair  (IBA,IEA,ISO,ISS)
neuron development  (IEA,ISO,ISS)

Cellular Component
aggresome  (IEA,ISO)
cytoplasm  (IBA,IEA,ISO)
nuclear body  (ISO)
nucleolus  (IEA)
nucleoplasm  (ISO)
nucleus  (ISO)
PML body  (IBA,IEA,ISO,ISS)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. GOA pipeline RGD automated data pipeline
3. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
Additional References at PubMed
PMID:19794497   PMID:21030584   PMID:22405347   PMID:22822062   PMID:22908287   PMID:24658003  


Genomics

Comparative Map Data
Tdp2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81740,656,969 - 40,668,362 (-)NCBIGRCr8
mRatBN7.21740,228,943 - 40,240,337 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1740,228,947 - 40,240,313 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1740,297,128 - 40,308,451 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01741,901,173 - 41,912,496 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01740,184,268 - 40,195,590 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01742,229,667 - 42,241,025 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1742,229,642 - 42,241,066 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01744,097,466 - 44,108,824 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41747,290,530 - 47,301,849 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1739,866,248 - 39,877,568 (-)NCBICelera
Cytogenetic Map17p11NCBI
TDP2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38624,649,979 - 24,666,899 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl624,649,979 - 24,666,930 (-)EnsemblGRCh38hg38GRCh38
GRCh37624,650,207 - 24,667,127 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36624,758,184 - 24,775,094 (-)NCBINCBI36Build 36hg18NCBI36
Build 34624,758,184 - 24,775,094NCBI
Celera625,883,542 - 25,900,457 (-)NCBICelera
Cytogenetic Map6p22.3NCBI
HuRef624,599,621 - 24,616,537 (-)NCBIHuRef
CHM1_1624,654,343 - 24,671,259 (-)NCBICHM1_1
T2T-CHM13v2.0624,520,363 - 24,537,292 (-)NCBIT2T-CHM13v2.0
Tdp2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391325,015,642 - 25,026,136 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1325,015,662 - 25,026,136 (+)EnsemblGRCm39 Ensembl
GRCm381324,831,659 - 24,842,153 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1324,831,679 - 24,842,153 (+)EnsemblGRCm38mm10GRCm38
MGSCv371324,923,528 - 24,934,022 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361324,839,150 - 24,849,611 (+)NCBIMGSCv36mm8
Celera1325,062,324 - 25,072,818 (+)NCBICelera
Cytogenetic Map13A3.1NCBI
cM Map1310.7NCBI
Tdp2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554832,375,313 - 2,388,892 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554832,375,213 - 2,385,354 (+)NCBIChiLan1.0ChiLan1.0
TDP2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2539,300,990 - 39,318,562 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1635,300,448 - 35,318,023 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0624,487,551 - 24,505,268 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1624,819,494 - 24,837,189 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl624,819,494 - 24,837,189 (-)Ensemblpanpan1.1panPan2
TDP2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13522,693,203 - 22,707,054 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3522,693,110 - 22,707,008 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3522,660,843 - 22,674,624 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03522,815,655 - 22,829,433 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3522,814,198 - 22,829,404 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13522,621,127 - 22,634,899 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03522,668,709 - 22,682,476 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03524,105,036 - 24,118,785 (-)NCBIUU_Cfam_GSD_1.0
Tdp2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024411772475 - 1,113 (-)NCBIHiC_Itri_2
SpeTri2.0NW_004948563494 - 1,113 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TDP2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl719,489,384 - 19,502,520 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1719,489,381 - 19,502,437 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2720,642,148 - 20,655,198 (-)NCBISscrofa10.2Sscrofa10.2susScr3
TDP2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11747,582,857 - 47,599,871 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1747,583,014 - 47,600,628 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604424,580,645 - 24,597,659 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tdp2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247562,363,718 - 2,375,152 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247562,363,400 - 2,374,839 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Tdp2
30 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:133
Count of miRNA genes:99
Interacting mature miRNAs:118
Transcripts:ENSRNOT00000059570
Prediction methods:Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1354581Bp247Blood pressure QTL 2474.5arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)17169599340Rat
2300002Iddm36Insulin dependent diabetes mellitus QTL 361.98blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)17999128640540197Rat
1354640Scl32Serum cholesterol level QTL 325.4blood HDL cholesterol amount (VT:0000184)blood high density lipoprotein cholesterol level (CMO:0000052)171578159260781592Rat
152023626Bp403Blood pressure QTL 4033.86arterial blood pressure trait (VT:2000000)172393042179524188Rat
2301412Kidm40Kidney mass QTL 400.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)173747984782479847Rat
9590107Sffal7Serum free fatty acids level QTL 74.810.001blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)172840914773409147Rat
2302377Scl61Serum cholesterol level QTL 614.36blood HDL cholesterol amount (VT:0000184)serum high density lipoprotein cholesterol level (CMO:0000361)172738994653481766Rat
70157Niddm32Non-insulin dependent diabetes mellitus QTL 324.34blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)172245492450909196Rat
724549Niddm56Non-insulin dependent diabetes mellitus QTL 560.03blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)173199078476990784Rat
1354651Lmblg2Limb length QTL 26tibia length (VT:0004357)tibia length (CMO:0000450)17429913069599340Rat
1354628Stl13Serum triglyceride level QTL 133.8blood triglyceride amount (VT:0002644)blood triglyceride level (CMO:0000118)172129303960781592Rat
1581512Cm55Cardiac mass QTL 552.80.05heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)172702794956836890Rat
10054088Scort28Serum corticosterone level QTL 282.040.0102blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)17452803849528038Rat
1354630Cm34Cardiac mass QTL 348.7heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)17429913069599340Rat
61394Bp8Blood pressure QTL 82.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)172308056759555013Rat
1559055Bp278Blood pressure QTL 2780.04arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)172365318468653184Rat
10450503Bp386Blood pressure QTL 3860.28arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)173136839162109574Rat
152025238Slep14Serum leptin concentration QTL 144.62blood leptin amount (VT:0005667)172418489079524188Rat
1354638Insul1Insulin level QTL 14.8blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)17429913069599340Rat
2313854Bp343Blood pressure QTL 3433.9life span trait (VT:0005372)age at time of death (CMO:0001193)173199078450909196Rat
2317054Aia12Adjuvant induced arthritis QTL 124.24joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)173828150983281509Rat
1331765Hrtrt15Heart rate QTL 154.094heart pumping trait (VT:2000009)heart rate (CMO:0000002)171533061355836425Rat
8552928Pigfal9Plasma insulin-like growth factor 1 level QTL 99blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)172840914773409147Rat
1300148Bp192Blood pressure QTL 1923.47arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)173455084373951021Rat
2317060Aia26Adjuvant induced arthritis QTL 263.22joint integrity trait (VT:0010548)right rear ankle joint diameter (CMO:0002150)173828150983281509Rat
2303627Vencon8Ventilatory control QTL 80.001respiration trait (VT:0001943)tidal volume (CMO:0000222)17452803849528038Rat
12903980Cm120Cardiac mass QTL 1200.002heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)172365318468653184Rat
12903981Am17Aortic mass QTL 170.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)172365318468653184Rat
4889955Bss93Bone structure and strength QTL 934.4tibia size trait (VT:0100001)tibia cortical bone volume to tibia total bone volume ratio (CMO:0001727)172702794960463643Rat
2303561Bw91Body weight QTL 912body mass (VT:0001259)body weight (CMO:0000012)17886846253868462Rat
12903982Kidm70Kidney mass QTL 700.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)172365318470974005Rat
12903978Cm118Cardiac mass QTL 1180.001heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)172365318468653184Rat
2324621Coatc5Coat color QTL 5coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)173136839173951021Rat
12903979Cm119Cardiac mass QTL 1190.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)172365318468653184Rat
1354619Bp242Blood pressure QTL 2426.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)172459934069599340Rat
1354596Bw32Body weight QTL 324.5body mass (VT:0001259)body weight (CMO:0000012)17429913060781592Rat
1354662Rf49Renal function QTL 492.9blood creatinine amount (VT:0005328)plasma creatinine level (CMO:0000537)17169599340Rat
152023740Bp406Blood pressure QTL 4066.06arterial blood pressure trait (VT:2000000)172393042179524188Rat
1354663Bvd5Brain ventricular dilatation QTL 53.510.001brain ventricle morphology trait (VT:0000822)hydrocephalus severity score (CMO:0001881)173199078481292925Rat
7488966Bp370Blood pressure QTL 3700.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)172365318457246843Rat
1354658Spl8Serum phospholipid level QTL 83.8blood VLDL phospholipid amount (VT:0010507)blood very low density lipoprotein phospholipid level (CMO:0001571)17160781592Rat
152023737Bp405Blood pressure QTL 4055.06arterial blood pressure trait (VT:2000000)2393042179524188Rat
1354659Scl68Serum cholesterol level QTL 683.9blood VLDL cholesterol amount (VT:0005144)blood very low density lipoprotein cholesterol level (CMO:0000648)171578159260781592Rat
152023736Bp404Blood pressure QTL 4043.78arterial blood pressure trait (VT:2000000)172393042179524188Rat
724528Uae4Urinary albumin excretion QTL 44.90.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)173583708569599340Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31

Sequence


Ensembl Acc Id: ENSRNOT00000059570   ⟹   ENSRNOP00000056326
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1740,228,947 - 40,240,313 (-)Ensembl
Rnor_6.0 Ensembl1742,229,642 - 42,241,066 (-)Ensembl
RefSeq Acc Id: NM_001034947   ⟹   NP_001030119
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81740,656,969 - 40,668,288 (-)NCBI
mRatBN7.21740,228,943 - 40,240,262 (-)NCBI
Rnor_6.01742,229,667 - 42,241,025 (-)NCBI
Rnor_5.01744,097,466 - 44,108,824 (-)NCBI
RGSC_v3.41747,290,530 - 47,301,849 (-)RGD
Celera1739,866,248 - 39,877,568 (-)RGD
Sequence:
RefSeq Acc Id: XM_063276691   ⟹   XP_063132761
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81740,659,085 - 40,668,362 (-)NCBI
RefSeq Acc Id: XM_063276692   ⟹   XP_063132762
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81740,658,496 - 40,668,362 (-)NCBI
RefSeq Acc Id: XR_005495318
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81740,659,085 - 40,668,362 (-)NCBI
mRatBN7.21740,231,032 - 40,240,337 (-)NCBI
RefSeq Acc Id: XR_005495319
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81740,659,085 - 40,668,362 (-)NCBI
mRatBN7.21740,228,943 - 40,240,337 (-)NCBI
RefSeq Acc Id: XR_010058918
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81740,659,085 - 40,668,361 (-)NCBI
RefSeq Acc Id: XR_010058919
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81740,659,085 - 40,668,361 (-)NCBI
RefSeq Acc Id: XR_010058920
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81740,659,085 - 40,668,361 (-)NCBI
RefSeq Acc Id: NP_001030119   ⟸   NM_001034947
- UniProtKB: Q3T1H5 (UniProtKB/Swiss-Prot),   A6KLF1 (UniProtKB/TrEMBL),   G3V9Q6 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000056326   ⟸   ENSRNOT00000059570
RefSeq Acc Id: XP_063132762   ⟸   XM_063276692
- Peptide Label: isoform X2
RefSeq Acc Id: XP_063132761   ⟸   XM_063276691
- Peptide Label: isoform X1
Protein Domains
Endonuclease/exonuclease/phosphatase

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q3T1H5-F1-model_v2 AlphaFold Q3T1H5 1-366 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13700442
Promoter ID:EPDNEW_R10966
Type:initiation region
Name:Tdp2_1
Description:tyrosyl-DNA phosphodiesterase 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01742,241,052 - 42,241,112EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1560342 AgrOrtholog
BioCyc Gene G2FUF-9423 BioCyc
Ensembl Genes ENSRNOG00000018246 Ensembl, UniProtKB/TrEMBL
  ENSRNOG00065022627 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000059570.4 UniProtKB/TrEMBL
  ENSRNOT00065038642 UniProtKB/Swiss-Prot
Gene3D-CATH 3.60.10.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  DNA helicase RuvA subunit, C-terminal domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7937874 IMAGE-MGC_LOAD
InterPro Endo/exonu/phosph_ase_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Endo/exonuclease/phosphatase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TDP2-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:498749 UniProtKB/Swiss-Prot
MGC_CLONE MGC:124734 IMAGE-MGC_LOAD
NCBI Gene 498749 ENTREZGENE
PANTHER TRAF AND TNF RECEPTOR-ASSOCIATED PROTEIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TYROSYL-DNA PHOSPHODIESTERASE 2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Exo_endo_phos UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  UBA_4 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Tdp2 PhenoGen
RatGTEx ENSRNOG00000018246 RatGTEx
  ENSRNOG00065022627 RatGTEx
Superfamily-SCOP SSF56219 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A6KLF1 ENTREZGENE, UniProtKB/TrEMBL
  G3V9Q6 ENTREZGENE, UniProtKB/TrEMBL
  Q3T1H5 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2011-08-01 Tdp2  tyrosyl-DNA phosphodiesterase 2  Ttrap  Traf and Tnf receptor associated protein  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-03-05 Ttrap  Traf and Tnf receptor associated protein  LOC498749  similar to putative TRAF and TNF receptor associated protein  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-02-09 LOC498749  similar to putative TRAF and TNF receptor associated protein      Symbol and Name status set to provisional 70820 PROVISIONAL