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GENE - TERM ANNOTATION REPORT

RGD ID: 1560342
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Tdp2
Name: tyrosyl-DNA phosphodiesterase 2
Acc ID: GO:0070260
Term: 5'-tyrosyl-DNA phosphodiesterase activity
Definition: Catalysis of the hydrolysis of 5'-phosphotyrosyl groups formed as covalent intermediates (in DNA backbone breakage) between DNA topoisomerase II and DNA.
Definition Source(s): PMID:16751265
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Tdp2enablesISOTDP2 (Homo sapiens)1624291RGD PMID:19794497 PMID:21030584 PMID:22405347 PMID:22822062

PMID:19794497 PMID:21030584 PMID:22405347 PMID:22822062
Tdp2enablesIEAUniProtKB:O95551 or ensembl:ENSP000003674401600115EnsemblGO_REF:0000107

GO_REF:0000107
Tdp2enablesIBAPANTHER:PTN001039821 or UniProtKB:O955511600115GO_CentralGO_REF:0000033

GO_REF:0000033
Tdp2enablesISSUniProtKB:O955511600115UniProtGO_REF:0000024

GO_REF:0000024
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