Ethe1 (ETHE1, persulfide dioxygenase) - Rat Genome Database

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Gene: Ethe1 (ETHE1, persulfide dioxygenase) Rattus norvegicus
Analyze
Symbol: Ethe1
Name: ETHE1, persulfide dioxygenase
RGD ID: 1311034
Description: Predicted to enable identical protein binding activity; iron ion binding activity; and sulfur dioxygenase activity. Predicted to be involved in glutathione metabolic process and hydrogen sulfide metabolic process. Predicted to be located in cytoplasm and nucleoplasm. Predicted to be active in mitochondrion. Human ortholog(s) of this gene implicated in ethylmalonic encephalopathy. Orthologous to human ETHE1 (ETHE1 persulfide dioxygenase); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: ethylmalonic encephalopathy 1; LOC292710; persulfide dioxygenase ETHE1, mitochondrial; protein ETHE1, mitochondrial
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8189,311,948 - 89,327,000 (+)NCBIGRCr8
mRatBN7.2180,184,037 - 80,199,092 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl180,183,894 - 80,199,052 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx185,576,393 - 85,591,434 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0194,127,481 - 94,142,531 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0187,332,138 - 87,347,179 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0181,457,008 - 81,472,061 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl181,456,984 - 81,472,097 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0182,716,410 - 82,731,463 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4179,875,629 - 79,890,681 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1179,953,739 - 79,968,786 (+)NCBI
Celera174,636,910 - 74,651,962 (+)NCBICelera
Cytogenetic Map1q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(1->4)-beta-D-glucan  (ISO)
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (EXP,ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dinitrotoluene  (EXP)
2-palmitoylglycerol  (ISO)
3,3',5-triiodo-L-thyronine  (EXP)
3-chloropropane-1,2-diol  (EXP)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
acrylamide  (EXP)
actinomycin D  (ISO)
aldrin  (ISO)
all-trans-retinoic acid  (ISO)
amphetamine  (EXP)
antirheumatic drug  (ISO)
arsenous acid  (ISO)
atrazine  (ISO)
benzo[a]pyrene  (ISO)
benzo[b]fluoranthene  (ISO)
beta-lapachone  (ISO)
bisphenol A  (EXP,ISO)
Bisphenol B  (ISO)
butanal  (ISO)
cadmium dichloride  (EXP)
carbon nanotube  (ISO)
CGP 52608  (ISO)
chlordecone  (ISO)
chlorpyrifos  (ISO)
chromium(6+)  (ISO)
cisplatin  (ISO)
clofibrate  (ISO)
clofibric acid  (EXP)
copper(II) sulfate  (ISO)
cyclosporin A  (ISO)
diarsenic trioxide  (ISO)
dibenz[a,h]anthracene  (ISO)
Dibutyl phosphate  (ISO)
diquat  (ISO)
diuron  (EXP)
dorsomorphin  (ISO)
doxorubicin  (ISO)
epoxiconazole  (ISO)
ethyl methanesulfonate  (ISO)
fipronil  (EXP)
folic acid  (ISO)
gentamycin  (EXP)
glafenine  (EXP)
glyphosate  (ISO)
hydrogen peroxide  (ISO)
inulin  (ISO)
iodide salt  (EXP)
ivermectin  (ISO)
leflunomide  (EXP)
methotrexate  (ISO)
N-nitrosodiethylamine  (EXP)
nefazodone  (EXP)
nickel atom  (ISO)
niclosamide  (ISO)
Nutlin-3  (ISO)
p-toluidine  (EXP)
paracetamol  (EXP,ISO)
perfluorododecanoic acid  (EXP)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (ISO)
pirinixic acid  (ISO)
potassium chromate  (ISO)
resveratrol  (ISO)
rotenone  (EXP)
SB 431542  (ISO)
senecionine  (EXP)
sodium arsenite  (ISO)
sodium dichromate  (EXP)
sodium fluoride  (ISO)
tetrachloroethene  (ISO)
tetrachloromethane  (ISO)
thapsigargin  (ISO)
thioacetamide  (EXP)
titanium dioxide  (ISO)
trichloroethene  (EXP)
tris(2-butoxyethyl) phosphate  (ISO)
troglitazone  (ISO)
valdecoxib  (EXP)
valproic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (ISO)
mitochondrion  (IBA,ISO)
nucleoplasm  (IEA,ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
3. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932   PMID:14651853   PMID:18614015   PMID:23144459   PMID:28299817  


Genomics

Comparative Map Data
Ethe1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8189,311,948 - 89,327,000 (+)NCBIGRCr8
mRatBN7.2180,184,037 - 80,199,092 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl180,183,894 - 80,199,052 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx185,576,393 - 85,591,434 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0194,127,481 - 94,142,531 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0187,332,138 - 87,347,179 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0181,457,008 - 81,472,061 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl181,456,984 - 81,472,097 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0182,716,410 - 82,731,463 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4179,875,629 - 79,890,681 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1179,953,739 - 79,968,786 (+)NCBI
Celera174,636,910 - 74,651,962 (+)NCBICelera
Cytogenetic Map1q21NCBI
ETHE1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381943,506,719 - 43,527,201 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1943,506,719 - 43,527,230 (-)EnsemblGRCh38hg38GRCh38
GRCh371944,010,871 - 44,031,353 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361948,702,711 - 48,723,236 (-)NCBINCBI36Build 36hg18NCBI36
Build 341948,702,711 - 48,723,236NCBI
Celera1940,811,624 - 40,834,029 (-)NCBICelera
Cytogenetic Map19q13.31NCBI
HuRef1940,440,766 - 40,462,063 (-)NCBIHuRef
CHM1_11944,012,533 - 44,033,058 (-)NCBICHM1_1
T2T-CHM13v2.01946,327,106 - 46,348,785 (-)NCBIT2T-CHM13v2.0
Ethe1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39724,286,968 - 24,308,350 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl724,286,968 - 24,308,350 (+)EnsemblGRCm39 Ensembl
GRCm38724,587,543 - 24,608,925 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl724,587,543 - 24,608,925 (+)EnsemblGRCm38mm10GRCm38
MGSCv37725,372,562 - 25,393,944 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36724,296,303 - 24,317,685 (+)NCBIMGSCv36mm8
Celera719,201,450 - 19,222,832 (+)NCBICelera
Cytogenetic Map7A3NCBI
cM Map711.66NCBI
Ethe1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555551,262,802 - 1,279,714 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555551,262,860 - 1,279,714 (-)NCBIChiLan1.0ChiLan1.0
ETHE1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22049,664,616 - 49,686,290 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11951,533,548 - 51,555,217 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01940,447,367 - 40,469,037 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
ETHE1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11111,583,690 - 111,607,420 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1111,471,522 - 111,607,386 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1111,063,414 - 111,087,138 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01112,193,836 - 112,217,585 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1112,081,868 - 112,217,551 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11111,782,087 - 111,805,730 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01111,415,757 - 111,439,468 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01112,300,036 - 112,323,637 (+)NCBIUU_Cfam_GSD_1.0
Ethe1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934916,378,763 - 16,403,464 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936706726,089 - 746,760 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936706726,106 - 750,733 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ETHE1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl650,375,841 - 50,396,237 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1650,375,836 - 50,395,769 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2646,148,306 - 46,150,857 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ETHE1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1637,024,015 - 37,045,628 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl637,024,014 - 37,045,737 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607316,563,865 - 16,584,962 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ethe1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046249071,057,768 - 1,073,003 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046249071,057,768 - 1,080,936 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Ethe1
179 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:50
Count of miRNA genes:46
Interacting mature miRNAs:49
Transcripts:ENSRNOT00000027075
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2313059Bss55Bone structure and strength QTL 553.20.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)143284731118944897Rat
631688Hcas2Hepatocarcinoma susceptibility QTL 230.0001liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)15925874115540829Rat
1578649Bmd8Bone mineral density QTL 84.9femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)14939317294393172Rat
1582234Gluco18Glucose level QTL 183.40.0003blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)178479925123479925Rat
1358359Sradr1Stress Responsive Adrenal Weight QTL 14.74adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)130882023123479925Rat
634314Niddm44Non-insulin dependent diabetes mellitus QTL 44blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)149393289199050459Rat
4889929Bss87Bone structure and strength QTL 876.7tibia area (VT:1000281)tibia-fibula cortical bone endosteal cross-sectional area (CMO:0001722)15389511782174945Rat
2313062Bmd73Bone mineral density QTL 733.90.0001tibia mineral mass (VT:1000283)compact volumetric bone mineral density (CMO:0001730)11148131282174945Rat
1578654Bss10Bone structure and strength QTL 104femur morphology trait (VT:0000559)femoral neck cortical cross-sectional area (CMO:0001702)149393172159356837Rat
1554320Bmd1Bone mineral density QTL 112.20.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)150910886060548Rat
2302059Pia36Pristane induced arthritis QTL 363.80.001blood immunoglobulin amount (VT:0002460)serum immunoglobulin G1 level (CMO:0002115)14333300288333002Rat
2313065Bss67Bone structure and strength QTL 673.10.0001tibia area (VT:1000281)tibia total energy absorbed before break (CMO:0001736)11148131282174945Rat
1300121Hrtrt1Heart rate QTL 13.7heart pumping trait (VT:2000009)heart rate (CMO:0000002)165789093115540829Rat
7421628Bp361Blood pressure QTL 3610.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)166023617118608521Rat
2313069Bss68Bone structure and strength QTL 682.90.0001tibia size trait (VT:0100001)tibia total energy absorbed before break (CMO:0001736)11148131282174945Rat
631495Bp96Blood pressure QTL 964.52arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)122340647102268831Rat
2313075Bss66Bone structure and strength QTL 663.40.0001tibia length (VT:0004357)tibia length (CMO:0000450)11148131282174945Rat
70225Bp58Blood pressure QTL 583.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)132356093162846471Rat
631512Scl6Serum cholesterol level QTL 69.6blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)17219768090508767Rat
2298545Neuinf8Neuroinflammation QTL 84.6nervous system integrity trait (VT:0010566)spinal cord beta-2 microglobulin mRNA level (CMO:0002125)157336763151090257Rat
2313072Bss53Bone structure and strength QTL 534.30.0001tibia length (VT:0004357)tibia length (CMO:0000450)143284731118944897Rat
10059597Bp377Blood pressure QTL 3773.420.025arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)132737458199368955Rat
2313078Bss54Bone structure and strength QTL 543.50.0001tibia area (VT:1000281)tibia midshaft cross-sectional area (CMO:0001717)143284731118944897Rat
2313077Bss69Bone structure and strength QTL 693.50.0001tibia strength trait (VT:1000284)bone polar moment of inertia (CMO:0001558)11148131282174945Rat
1549903Bp267Blood pressure QTL 267arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)177876254106047988Rat
2313402Anxrr24Anxiety related response QTL 24aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)148963584144267916Rat
61342Bp27Blood pressure QTL 273.40.0006arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)15673266898773277Rat
1300172Bp172Blood pressure QTL 1723.56arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)13273727390665040Rat
4889962Bss94Bone structure and strength QTL 943.8tibia area (VT:1000281)tibia-fibula cortical bone endosteal cross-sectional area (CMO:0001722)14936146582174945Rat
61344Bp29Blood pressure QTL 297.5arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)178350581123350581Rat
1358192Ept13Estrogen-induced pituitary tumorigenesis QTL 133.4pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)177494165122494165Rat
2313094Bss58Bone structure and strength QTL 583.70.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)143284731118944897Rat
6903308Scl36Serum cholesterol QTL 3620.0125blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)15386304190532583Rat
2313092Bmd72Bone mineral density QTL 722.50.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)11148131282174945Rat
2300164Bmd44Bone mineral density QTL 445.40.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)156949932101949932Rat
2313099Bss56Bone structure and strength QTL 562.40.0001tibia size trait (VT:0100001)tibia midshaft endosteal cross-sectional area (CMO:0001716)143284731118944897Rat
2313098Bmd70Bone mineral density QTL 703.60.0001tibia mineral mass (VT:1000283)compact volumetric bone mineral density (CMO:0001730)143284731118944897Rat
2313097Bss70Bone structure and strength QTL 703.50.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)11148131282174945Rat
152025249Scl82Serum cholesterol level QTL 824.77blood cholesterol amount (VT:0000180)15034351099980958Rat
10054135Gmadr2Adrenal mass QTL 21.970.0129adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)177857876122857876Rat
7411712Strs4Sensitivity to stroke QTL 48.7cerebrum integrity trait (VT:0010549)percentage of study population developing cerebrovascular lesions during a period of time (CMO:0000932)178430536123430536Rat
4889919Bss86Bone structure and strength QTL 864.1tibia area (VT:1000281)tibia midshaft total cross-sectional area (CMO:0001715)15389511782174945Rat
2313051Bss57Bone structure and strength QTL 573.70.0001tibia strength trait (VT:1000284)bone polar moment of inertia (CMO:0001558)143284731118944897Rat
61433Cia2Collagen induced arthritis QTL 25joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)17843075491209302Rat

Markers in Region
RH139493  
Rat AssemblyChrPosition (strand)SourceJBrowse
RH 3.4 Map1823.9UniSTS
Cytogenetic Map1q21UniSTS
ETHE1  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2180,197,764 - 80,198,264 (+)MAPPERmRatBN7.2
Rnor_6.0181,470,734 - 81,471,233NCBIRnor6.0
Rnor_5.0182,730,136 - 82,730,635UniSTSRnor5.0
RGSC_v3.4179,889,354 - 79,889,853UniSTSRGSC3.4
Celera174,650,635 - 74,651,134UniSTS
Cytogenetic Map1q21UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31

Sequence


Ensembl Acc Id: ENSRNOT00000027075   ⟹   ENSRNOP00000027076
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl180,183,894 - 80,199,052 (+)Ensembl
Rnor_6.0 Ensembl181,456,984 - 81,472,097 (+)Ensembl
RefSeq Acc Id: NM_001106234   ⟹   NP_001099704
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8189,311,948 - 89,327,000 (+)NCBI
mRatBN7.2180,184,037 - 80,199,092 (+)NCBI
Rnor_6.0181,457,008 - 81,472,061 (+)NCBI
Rnor_5.0182,716,410 - 82,731,463 (+)NCBI
RGSC_v3.4179,875,629 - 79,890,681 (+)RGD
Celera174,636,910 - 74,651,962 (+)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_001099704 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAI58849 (Get FASTA)   NCBI Sequence Viewer  
  EDM08081 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000027076.4
RefSeq Acc Id: NP_001099704   ⟸   NM_001106234
- UniProtKB: B0BNJ4 (UniProtKB/TrEMBL),   A6J903 (UniProtKB/TrEMBL),   F7EWE8 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000027076   ⟸   ENSRNOT00000027075
Protein Domains
Metallo-beta-lactamase

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-B0BNJ4-F1-model_v2 AlphaFold B0BNJ4 1-254 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13689801
Promoter ID:EPDNEW_R325
Type:multiple initiation site
Name:Ethe1_1
Description:ETHE1, persulfide dioxygenase
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0181,457,037 - 81,457,097EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1311034 AgrOrtholog
BioCyc Gene G2FUF-60436 BioCyc
BioCyc Pathway PWY-5285 [sulfide oxidation III (to sulfite)] BioCyc
  PWY-7927 [sulfide oxidation IV (mitochondria)] BioCyc
BioCyc Pathway Image PWY-5285 BioCyc
  PWY-7927 BioCyc
Ensembl Genes ENSRNOG00000019982 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000027075.7 UniProtKB/TrEMBL
Gene3D-CATH 3.60.15.10 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7444454 IMAGE-MGC_LOAD
InterPro Blactmase-like UniProtKB/TrEMBL
  Metallo-hydrolase/OxRdtase UniProtKB/TrEMBL
  Mito_Persulfide_Diox UniProtKB/TrEMBL
  POD-like_MBL-fold UniProtKB/TrEMBL
KEGG Report rno:292710 UniProtKB/TrEMBL
MGC_CLONE MGC:188327 IMAGE-MGC_LOAD
NCBI Gene 292710 ENTREZGENE
PANTHER PERSULFIDE DIOXYGENASE ETHE1 UniProtKB/TrEMBL
  PERSULFIDE DIOXYGENASE ETHE1, MITOCHONDRIAL UniProtKB/TrEMBL
Pfam Lactamase_B UniProtKB/TrEMBL
PhenoGen Ethe1 PhenoGen
RatGTEx ENSRNOG00000019982 RatGTEx
SMART Lactamase_B UniProtKB/TrEMBL
Superfamily-SCOP SSF56281 UniProtKB/TrEMBL
UniProt A6J903 ENTREZGENE, UniProtKB/TrEMBL
  B0BNJ4 ENTREZGENE
  F7EWE8 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary B0BNJ4 UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-05-04 Ethe1  ETHE1, persulfide dioxygenase  Ethe1  ethylmalonic encephalopathy 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Ethe1  ethylmalonic encephalopathy 1   Ethe1_predicted  ethylmalonic encephalopathy 1 (predicted)  'predicted' is removed 2292626 APPROVED