Ethe1 (ETHE1, persulfide dioxygenase) - Rat Genome Database

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Gene: Ethe1 (ETHE1, persulfide dioxygenase) Rattus norvegicus
Analyze
Symbol: Ethe1
Name: ETHE1, persulfide dioxygenase
RGD ID: 1311034
Description: Predicted to enable identical protein binding activity; iron ion binding activity; and sulfur dioxygenase activity. Predicted to be involved in glutathione metabolic process and hydrogen sulfide metabolic process. Predicted to be located in mitochondrion and nucleoplasm. Human ortholog(s) of this gene implicated in ethylmalonic encephalopathy. Orthologous to human ETHE1 (ETHE1 persulfide dioxygenase); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: ethylmalonic encephalopathy 1; LOC292710; persulfide dioxygenase ETHE1, mitochondrial; protein ETHE1, mitochondrial
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8189,311,948 - 89,327,000 (+)NCBIGRCr8
mRatBN7.2180,184,037 - 80,199,092 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl180,183,894 - 80,199,052 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx185,576,393 - 85,591,434 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0194,127,481 - 94,142,531 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0187,332,138 - 87,347,179 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0181,457,008 - 81,472,061 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl181,456,984 - 81,472,097 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0182,716,410 - 82,731,463 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4179,875,629 - 79,890,681 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1179,953,739 - 79,968,786 (+)NCBI
Celera174,636,910 - 74,651,962 (+)NCBICelera
Cytogenetic Map1q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Ethe1Ratethylmalonic encephalopathy  ISOETHE1 (Homo sapiens)8554872ClinVar Annotator: match by term: Ethylmalonic encephalopathyClinVarPMID:14732903 more ...
Ethe1Ratgenetic disease  ISOETHE1 (Homo sapiens)8554872ClinVar Annotator: match by term: Inborn genetic diseasesClinVarPMID:25741868 and PMID:28492532
Ethe1RatNervous System Malformations  ISOETHE1 (Homo sapiens)8554872ClinVar Annotator: match by term: Abnormality of the nervous systemClinVarPMID:16183799 more ...
Ethe1Ratschizophrenia  ISOETHE1 (Homo sapiens)8554872ClinVar Annotator: match by term: SchizophreniaClinVarPMID:21681106 and PMID:30208311
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Ethe1Ratethylmalonic encephalopathy  ISOETHE1 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTD 
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Ethe1Ratethylmalonic encephalopathy  ISSEthe1 (Mus musculus)13592920OMIM:602473MouseDO 
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Ethe1Ratethylmalonic encephalopathy  ISOETHE1 (Homo sapiens)7240710 OMIM 

1 to 20 of 122 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Ethe1Rat(1->4)-beta-D-glucan multiple interactionsISOEthe1 (Mus musculus)6480464[perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of ETHE1 mRNACTDPMID:36331819
Ethe1Rat1,2-dimethylhydrazine multiple interactionsISOEthe1 (Mus musculus)6480464[1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ETHE1 mRNACTDPMID:22206623
Ethe1Rat17beta-estradiol affects expressionISOETHE1 (Homo sapiens)6480464Estradiol affects the expression of ETHE1 mRNACTDPMID:22574217
Ethe1Rat17beta-estradiol decreases expressionISOETHE1 (Homo sapiens)6480464Estradiol results in decreased expression of ETHE1 mRNACTDPMID:31614463
Ethe1Rat17beta-estradiol increases expressionISOEthe1 (Mus musculus)6480464Estradiol results in increased expression of ETHE1 mRNACTDPMID:39298647
Ethe1Rat17beta-estradiol affects expressionEXP 6480464Estradiol affects the expression of ETHE1 mRNACTDPMID:32145629
Ethe1Rat2,3,7,8-tetrachlorodibenzodioxine affects expressionISOEthe1 (Mus musculus)6480464Tetrachlorodibenzodioxin affects the expression of ETHE1 mRNACTDPMID:21570461
Ethe1Rat2,3,7,8-tetrachlorodibenzodioxine increases expressionEXP 6480464Tetrachlorodibenzodioxin results in increased expression of ETHE1 mRNACTDPMID:33387578 and PMID:34747641
Ethe1Rat2,3,7,8-tetrachlorodibenzodioxine decreases expressionEXP 6480464Tetrachlorodibenzodioxin results in decreased expression of ETHE1 mRNACTDPMID:21215274 and PMID:21724226
Ethe1Rat2,4-dinitrotoluene affects expressionEXP 64804642 and 4-dinitrotoluene affects the expression of ETHE1 mRNACTDPMID:21346803
Ethe1Rat2,6-dimethoxyphenol multiple interactionsISOETHE1 (Homo sapiens)6480464[pyrogallol 1 more ...CTDPMID:38598786
Ethe1Rat2-palmitoylglycerol increases expressionISOETHE1 (Homo sapiens)64804642-palmitoylglycerol results in increased expression of ETHE1 mRNACTDPMID:37199045
Ethe1Rat3,3',5-triiodo-L-thyronine increases expressionEXP 6480464Triiodothyronine results in increased expression of ETHE1 mRNACTDPMID:28299817
Ethe1Rat3-chloropropane-1,2-diol increases expressionEXP 6480464alpha-Chlorohydrin results in increased expression of ETHE1 mRNACTDPMID:28522335
Ethe1Rat4,4'-sulfonyldiphenol multiple interactionsISOEthe1 (Mus musculus)6480464[bisphenol S co-treated with Tretinoin] results in decreased expression of ETHE1 mRNACTDPMID:30951980
Ethe1Rat4,4'-sulfonyldiphenol increases methylationISOEthe1 (Mus musculus)6480464bisphenol S results in increased methylation of ETHE1 exonCTDPMID:33297965
Ethe1Rat4,4'-sulfonyldiphenol increases expressionISOEthe1 (Mus musculus)6480464bisphenol S results in increased expression of ETHE1 mRNACTDPMID:39298647
Ethe1Rat4-hydroxyphenyl retinamide increases expressionISOEthe1 (Mus musculus)6480464Fenretinide results in increased expression of ETHE1 mRNACTDPMID:28973697
Ethe1Ratacrylamide increases expressionEXP 6480464Acrylamide results in increased expression of ETHE1 mRNACTDPMID:28959563
Ethe1Ratactinomycin D multiple interactionsISOETHE1 (Homo sapiens)6480464[Dactinomycin co-treated with nutlin 3] results in increased secretion of ETHE1 proteinCTDPMID:38460933

1 to 20 of 122 rows

Biological Process

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Ethe1Ratglutathione metabolic process involved_inISOETHE1 (Homo sapiens)1624291 PMID:23144459RGDPMID:23144459
Ethe1Ratglutathione metabolic process involved_inIEAInterPro:IPR0445281600115GO_REF:0000002InterProGO_REF:0000002
Ethe1Ratglutathione metabolic process involved_inIEAUniProtKB:O95571 and ensembl:ENSP000002921471600115GO_REF:0000107EnsemblGO_REF:0000107
Ethe1Rathydrogen sulfide metabolic process involved_inISOETHE1 (Homo sapiens)1624291 PMID:23144459RGDPMID:23144459
Ethe1Rathydrogen sulfide metabolic process involved_inIEAUniProtKB:O95571 and ensembl:ENSP000002921471600115GO_REF:0000107EnsemblGO_REF:0000107

Cellular Component

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Ethe1Ratcytoplasm located_inISOETHE1 (Homo sapiens)1624291 RGDGO_REF:0000054
Ethe1Ratcytoplasm located_inIEAUniProtKB:O95571 and ensembl:ENSP000002921471600115GO_REF:0000107EnsemblGO_REF:0000107
Ethe1Ratmitochondrion located_inISOETHE1 (Homo sapiens)1624291 RGDGO_REF:0000052
Ethe1Ratmitochondrion located_inIEAUniProtKB:O95571 and ensembl:ENSP000002921471600115GO_REF:0000107EnsemblGO_REF:0000107
Ethe1Ratmitochondrion located_inIEAUniProtKB:A0A0S2Z5B3 and ensembl:ENSP000002921471600115GO_REF:0000107EnsemblGO_REF:0000107
Ethe1Ratnucleoplasm located_inISOETHE1 (Homo sapiens)1624291 RGDGO_REF:0000052
Ethe1Ratnucleoplasm located_inIEAUniProtKB:O95571 and ensembl:ENSP000002921471600115GO_REF:0000107EnsemblGO_REF:0000107
Ethe1Ratnucleoplasm located_inIEAUniProtKB:A0A0S2Z5B3 and ensembl:ENSP000002921471600115GO_REF:0000107EnsemblGO_REF:0000107

Molecular Function
1 to 9 of 9 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Ethe1Ratidentical protein binding enablesISOETHE1 (Homo sapiens)1624291UniProtKB:O95571 and PMID:32296183RGDPMID:32296183
Ethe1Ratidentical protein binding enablesIEAUniProtKB:O95571 and ensembl:ENSP000002921471600115GO_REF:0000107EnsemblGO_REF:0000107
Ethe1Ratiron ion binding enablesISOETHE1 (Homo sapiens)1624291 PMID:23144459RGDPMID:23144459
Ethe1Ratiron ion binding enablesIEAUniProtKB:O95571 and ensembl:ENSP000002921471600115GO_REF:0000107EnsemblGO_REF:0000107
Ethe1Ratmetal ion binding enablesIEAUniProtKB-KW:KW-04791600115GO_REF:0000043UniProtGO_REF:0000043
Ethe1Ratprotein binding enablesISOETHE1 (Homo sapiens)1624291UniProtKB:Q3LHN2 more ...RGDPMID:32296183
Ethe1Ratsulfur dioxygenase activity enablesISOETHE1 (Homo sapiens)1624291 PMID:23144459RGDPMID:23144459
Ethe1Ratsulfur dioxygenase activity enablesIEAInterPro:IPR0445281600115GO_REF:0000002InterProGO_REF:0000002
Ethe1Ratsulfur dioxygenase activity enablesIEAUniProtKB:O95571 and ensembl:ENSP000002921471600115GO_REF:0000107EnsemblGO_REF:0000107
1 to 9 of 9 rows


#
Reference Title
Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
3. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
PMID:12477932   PMID:14651853   PMID:18614015   PMID:23144459   PMID:28299817  



Ethe1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8189,311,948 - 89,327,000 (+)NCBIGRCr8
mRatBN7.2180,184,037 - 80,199,092 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl180,183,894 - 80,199,052 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx185,576,393 - 85,591,434 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0194,127,481 - 94,142,531 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0187,332,138 - 87,347,179 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0181,457,008 - 81,472,061 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl181,456,984 - 81,472,097 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0182,716,410 - 82,731,463 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4179,875,629 - 79,890,681 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1179,953,739 - 79,968,786 (+)NCBI
Celera174,636,910 - 74,651,962 (+)NCBICelera
Cytogenetic Map1q21NCBI
ETHE1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381943,506,719 - 43,527,201 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1943,506,719 - 43,527,230 (-)EnsemblGRCh38hg38GRCh38
GRCh371944,010,871 - 44,031,353 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361948,702,711 - 48,723,236 (-)NCBINCBI36Build 36hg18NCBI36
Build 341948,702,711 - 48,723,236NCBI
Celera1940,811,624 - 40,834,029 (-)NCBICelera
Cytogenetic Map19q13.31NCBI
HuRef1940,440,766 - 40,462,063 (-)NCBIHuRef
CHM1_11944,012,533 - 44,033,058 (-)NCBICHM1_1
T2T-CHM13v2.01946,327,106 - 46,348,785 (-)NCBIT2T-CHM13v2.0
Ethe1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39724,286,968 - 24,308,350 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl724,286,968 - 24,308,350 (+)EnsemblGRCm39 Ensembl
GRCm38724,587,543 - 24,608,925 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl724,587,543 - 24,608,925 (+)EnsemblGRCm38mm10GRCm38
MGSCv37725,372,562 - 25,393,944 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36724,296,303 - 24,317,685 (+)NCBIMGSCv36mm8
Celera719,201,450 - 19,222,832 (+)NCBICelera
Cytogenetic Map7A3NCBI
cM Map711.66NCBI
Ethe1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555551,262,802 - 1,279,714 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555551,262,860 - 1,279,714 (-)NCBIChiLan1.0ChiLan1.0
ETHE1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22049,664,616 - 49,686,290 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11951,533,548 - 51,555,217 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01940,447,367 - 40,469,037 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
ETHE1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11111,583,690 - 111,607,420 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1111,471,522 - 111,607,386 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1111,063,414 - 111,087,138 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01112,193,836 - 112,217,585 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1112,081,868 - 112,217,551 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11111,782,087 - 111,805,730 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01111,415,757 - 111,439,468 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01112,300,036 - 112,323,637 (+)NCBIUU_Cfam_GSD_1.0
Ethe1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934916,378,763 - 16,403,464 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936706726,089 - 746,760 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936706726,106 - 750,733 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ETHE1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl650,375,841 - 50,396,237 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1650,375,836 - 50,395,769 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2646,148,306 - 46,150,857 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ETHE1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1637,024,015 - 37,045,628 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl637,024,014 - 37,045,737 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607316,563,865 - 16,584,962 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ethe1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046249071,057,768 - 1,073,003 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046249071,057,768 - 1,080,936 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

.

.
Variants in Ethe1
179 total Variants

Predicted Target Of
Summary Value
Count of predictions:50
Count of miRNA genes:46
Interacting mature miRNAs:49
Transcripts:ENSRNOT00000027075
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 44 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
2313059Bss55Bone structure and strength QTL 553.20.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)143284731118944897Rat
631688Hcas2Hepatocarcinoma susceptibility QTL 230.0001liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)15925874115540829Rat
1578649Bmd8Bone mineral density QTL 84.9femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)14939317294393172Rat
1582234Gluco18Glucose level QTL 183.40.0003blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)178479925123479925Rat
1358359Sradr1Stress Responsive Adrenal Weight QTL 14.74adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)130882023123479925Rat
634314Niddm44Non-insulin dependent diabetes mellitus QTL 44blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)149393289199050459Rat
4889929Bss87Bone structure and strength QTL 876.7tibia area (VT:1000281)tibia-fibula cortical bone endosteal cross-sectional area (CMO:0001722)15389511782174945Rat
2313062Bmd73Bone mineral density QTL 733.90.0001tibia mineral mass (VT:1000283)compact volumetric bone mineral density (CMO:0001730)11148131282174945Rat
1578654Bss10Bone structure and strength QTL 104femur morphology trait (VT:0000559)femoral neck cortical cross-sectional area (CMO:0001702)149393172159356837Rat
1554320Bmd1Bone mineral density QTL 112.20.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)150910886060548Rat

1 to 10 of 44 rows
RH139493  
Rat AssemblyChrPosition (strand)SourceJBrowse
RH 3.4 Map1823.9UniSTS
Cytogenetic Map1q21UniSTS
ETHE1  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr8189,325,673 - 89,326,172 (+)Marker Load Pipeline
mRatBN7.2180,197,764 - 80,198,264 (+)MAPPERmRatBN7.2
Rnor_6.0181,470,734 - 81,471,233NCBIRnor6.0
Rnor_5.0182,730,136 - 82,730,635UniSTSRnor5.0
RGSC_v3.4179,889,354 - 79,889,853UniSTSRGSC3.4
Celera174,650,635 - 74,651,134UniSTS
Cytogenetic Map1q21UniSTS




alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31



Ensembl Acc Id: ENSRNOT00000027075   ⟹   ENSRNOP00000027076
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl180,183,894 - 80,199,052 (+)Ensembl
Rnor_6.0 Ensembl181,456,984 - 81,472,097 (+)Ensembl
RefSeq Acc Id: NM_001106234   ⟹   NP_001099704
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8189,311,948 - 89,327,000 (+)NCBI
mRatBN7.2180,184,037 - 80,199,092 (+)NCBI
Rnor_6.0181,457,008 - 81,472,061 (+)NCBI
Rnor_5.0182,716,410 - 82,731,463 (+)NCBI
RGSC_v3.4179,875,629 - 79,890,681 (+)RGD
Celera174,636,910 - 74,651,962 (+)RGD
Sequence:
Protein RefSeqs NP_001099704 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAI58849 (Get FASTA)   NCBI Sequence Viewer  
  EDM08081 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000027076
  ENSRNOP00000027076.4
RefSeq Acc Id: NP_001099704   ⟸   NM_001106234
- UniProtKB: B0BNJ4 (UniProtKB/TrEMBL),   A6J903 (UniProtKB/TrEMBL),   F7EWE8 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000027076   ⟸   ENSRNOT00000027075
Metallo-beta-lactamase

Name Modeler Protein Id AA Range Protein Structure
AF-B0BNJ4-F1-model_v2 AlphaFold B0BNJ4 1-254 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

RGD ID:13689801
Promoter ID:EPDNEW_R325
Type:multiple initiation site
Name:Ethe1_1
Description:ETHE1, persulfide dioxygenase
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0181,457,037 - 81,457,097EPDNEW


1 to 28 of 28 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-60436 BioCyc
BioCyc Pathway PWY-5285 [sulfide oxidation III (to sulfite)] BioCyc
  PWY-7927 [sulfide oxidation IV (mitochondria)] BioCyc
BioCyc Pathway Image PWY-5285 BioCyc
  PWY-7927 BioCyc
Ensembl Genes ENSRNOG00000019982 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000027075 ENTREZGENE
  ENSRNOT00000027075.7 UniProtKB/TrEMBL
Gene3D-CATH 3.60.15.10 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7444454 IMAGE-MGC_LOAD
InterPro Blactmase-like UniProtKB/TrEMBL
  Metallo-hydrolase/OxRdtase UniProtKB/TrEMBL
  Mito_Persulfide_Diox UniProtKB/TrEMBL
  POD-like_MBL-fold UniProtKB/TrEMBL
KEGG Report rno:292710 UniProtKB/TrEMBL
MGC_CLONE MGC:188327 IMAGE-MGC_LOAD
NCBI Gene 292710 ENTREZGENE
PANTHER PERSULFIDE DIOXYGENASE ETHE1 UniProtKB/TrEMBL
  PERSULFIDE DIOXYGENASE ETHE1, MITOCHONDRIAL UniProtKB/TrEMBL
Pfam Lactamase_B UniProtKB/TrEMBL
PhenoGen Ethe1 PhenoGen
RatGTEx ENSRNOG00000019982 RatGTEx
SMART Lactamase_B UniProtKB/TrEMBL
Superfamily-SCOP SSF56281 UniProtKB/TrEMBL
UniProt A6J903 ENTREZGENE, UniProtKB/TrEMBL
  B0BNJ4 ENTREZGENE
  F7EWE8 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary B0BNJ4 UniProtKB/TrEMBL
1 to 28 of 28 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-05-04 Ethe1  ETHE1, persulfide dioxygenase  Ethe1  ethylmalonic encephalopathy 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Ethe1  ethylmalonic encephalopathy 1   Ethe1_predicted  ethylmalonic encephalopathy 1 (predicted)  'predicted' is removed 2292626 APPROVED