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Gene: ETHE1 (ETHE1 persulfide dioxygenase) Chlorocebus sabaeus

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Symbol:

ETHE1

Name:

ETHE1 persulfide dioxygenase

RGD ID:

18656218

Description:

ENCODES a protein that exhibits identical protein binding (inferred); iron ion binding (inferred); metal ion binding (inferred); INVOLVED IN glutathione metabolic process (inferred); hydrogen sulfide metabolic process (inferred); ASSOCIATED WITH ethylmalonic encephalopathy (ortholog); genetic disease (ortholog); Nervous System Malformations (ortholog); FOUND IN cytoplasm (inferred); mitochondrion (inferred); nucleoplasm (inferred)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

persulfide dioxygenase ETHE1, mitochondrial

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

ChlSab1.1 - Green Monkey 1.1 Assembly

Position:

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	6	37,024,015 - 37,045,628 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	6	37,024,014 - 37,045,737 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666073	16,563,865 - 16,584,962 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
ETHE1	Green Monkey	ethylmalonic encephalopathy		ISO	ETHE1 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Ethylmalonic encephalopathy	ClinVar	PMID:14732903 more ...
ETHE1	Green Monkey	genetic disease		ISO	ETHE1 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Inborn genetic diseases	ClinVar	PMID:25741868 and PMID:28492532
ETHE1	Green Monkey	Nervous System Malformations		ISO	ETHE1 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Abnormality of the nervous system	ClinVar	PMID:16183799 more ...
ETHE1	Green Monkey	schizophrenia		ISO	ETHE1 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Schizophrenia	ClinVar	PMID:21681106 and PMID:30208311

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
ETHE1	Green Monkey	ethylmalonic encephalopathy		ISO	ETHE1 (Homo sapiens)	7240710		OMIM

Biological Process

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
ETHE1	Green Monkey	glutathione metabolic process	involved_in	IEA	PANTHER:PTN000232613	150520179		TreeGrafter	GO_REF:0000118
ETHE1	Green Monkey	glutathione metabolic process	involved_in	IEA	InterPro:IPR044528	150520179		InterPro	GO_REF:0000002
ETHE1	Green Monkey	glutathione metabolic process	involved_in	IEA	UniProtKB:O95571 and ensembl:ENSP00000292147	150520179		Ensembl	GO_REF:0000107
ETHE1	Green Monkey	hydrogen sulfide metabolic process	involved_in	IEA	PANTHER:PTN000232613	150520179		TreeGrafter	GO_REF:0000118
ETHE1	Green Monkey	hydrogen sulfide metabolic process	involved_in	IEA	UniProtKB:O95571 and ensembl:ENSP00000292147	150520179		Ensembl	GO_REF:0000107

Cellular Component

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
ETHE1	Green Monkey	cytoplasm	located_in	IEA	UniProtKB:O95571 and ensembl:ENSP00000292147	150520179		Ensembl	GO_REF:0000107
ETHE1	Green Monkey	mitochondrion	located_in	IEA	PANTHER:PTN000232613	150520179		TreeGrafter	GO_REF:0000118
ETHE1	Green Monkey	mitochondrion	located_in	IEA	UniProtKB:A0A0S2Z5B3 more ...	150520179		Ensembl	GO_REF:0000107
ETHE1	Green Monkey	nucleoplasm	located_in	IEA	UniProtKB:A0A0S2Z5B3 more ...	150520179		Ensembl	GO_REF:0000107

Molecular Function

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
ETHE1	Green Monkey	identical protein binding	enables	IEA	UniProtKB:O95571 and ensembl:ENSP00000292147	150520179		Ensembl	GO_REF:0000107
ETHE1	Green Monkey	iron ion binding	enables	IEA	UniProtKB:O95571 and ensembl:ENSP00000292147	150520179		Ensembl	GO_REF:0000107
ETHE1	Green Monkey	metal ion binding	enables	IEA	UniProtKB-KW:KW-0479	150520179		UniProt	GO_REF:0000043
ETHE1	Green Monkey	protein binding	enables	ISO	UniProtKB:Q3LHN2 more ...	9068941	PMID:32296183	IntAct	PMID:32296183
ETHE1	Green Monkey	sulfur dioxygenase activity	enables	IEA	PANTHER:PTN000232613	150520179		TreeGrafter	GO_REF:0000118
ETHE1	Green Monkey	sulfur dioxygenase activity	enables	IEA	UniProtKB:O95571 and ensembl:ENSP00000292147	150520179		Ensembl	GO_REF:0000107
ETHE1	Green Monkey	sulfur dioxygenase activity	enables	IEA	InterPro:IPR044528	150520179		InterPro	GO_REF:0000002

PMID:22301074	PMID:30032202

ETHE1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	6	37,024,015 - 37,045,628 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	6	37,024,014 - 37,045,737 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666073	16,563,865 - 16,584,962 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

ETHE1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	19	43,506,719 - 43,527,201 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	19	43,506,719 - 43,527,230 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	19	44,010,871 - 44,031,353 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	19	48,702,711 - 48,723,236 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	19	48,702,711 - 48,723,236	NCBI
Celera	19	40,811,624 - 40,834,029 (-)	NCBI		Celera
Cytogenetic Map	19	q13.31	NCBI
HuRef	19	40,440,766 - 40,462,063 (-)	NCBI		HuRef
CHM1_1	19	44,012,533 - 44,033,058 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	19	46,327,106 - 46,348,785 (-)	NCBI		T2T-CHM13v2.0

Ethe1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	7	24,286,968 - 24,308,350 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	7	24,286,968 - 24,308,350 (+)	Ensembl		GRCm39 Ensembl
GRCm38	7	24,587,543 - 24,608,925 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	7	24,587,543 - 24,608,925 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	7	25,372,562 - 25,393,944 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	7	24,296,303 - 24,317,685 (+)	NCBI		MGSCv36	mm8
Celera	7	19,201,450 - 19,222,832 (+)	NCBI		Celera
Cytogenetic Map	7	A3	NCBI
cM Map	7	11.66	NCBI

Ethe1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	89,311,948 - 89,327,000 (+)	NCBI		GRCr8
mRatBN7.2	1	80,184,037 - 80,199,092 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	80,183,894 - 80,199,052 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	1	85,576,393 - 85,591,434 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	94,127,481 - 94,142,531 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	87,332,138 - 87,347,179 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	81,457,008 - 81,472,061 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	81,456,984 - 81,472,097 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	1	82,716,410 - 82,731,463 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	1	79,875,629 - 79,890,681 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	1	79,953,739 - 79,968,786 (+)	NCBI
Celera	1	74,636,910 - 74,651,962 (+)	NCBI		Celera
Cytogenetic Map	1	q21	NCBI

Ethe1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955555	1,262,802 - 1,279,714 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955555	1,262,860 - 1,279,714 (-)	NCBI	ChiLan1.0	ChiLan1.0

ETHE1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	20	49,664,616 - 49,686,290 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	19	51,533,548 - 51,555,217 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	19	40,447,367 - 40,469,037 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3

ETHE1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	1	111,583,690 - 111,607,420 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	1	111,471,522 - 111,607,386 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	1	111,063,414 - 111,087,138 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	1	112,193,836 - 112,217,585 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	1	112,081,868 - 112,217,551 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	1	111,782,087 - 111,805,730 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	1	111,415,757 - 111,439,468 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	1	112,300,036 - 112,323,637 (+)	NCBI		UU_Cfam_GSD_1.0

Ethe1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024409349	16,378,763 - 16,403,464 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936706	726,089 - 746,760 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936706	726,106 - 750,733 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

ETHE1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	6	50,375,841 - 50,396,237 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	6	50,375,836 - 50,395,769 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	6	46,148,306 - 46,150,857 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

Ethe1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624907	1,057,768 - 1,073,003 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624907	1,057,768 - 1,080,936 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants in ETHE1
549 total Variants

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

ectoderm	endocrine system	hemolymphoid system	mesenchyme	mesoderm	nervous system	reproductive system
76	36	20	36	36	60	20


RefSeq Transcripts	XM_007997019	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_007997020	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JACDXN010000041	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSCSAT00000001434 ⟹ ENSCSAP00000014644

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
ChlSab1.1 Ensembl	6	37,024,014 - 37,045,737 (-)	Ensembl

RefSeq Acc Id:

XM_007997019 ⟹ XP_007995210

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
ChlSab1.1	6	37,024,015 - 37,045,628 (-)	NCBI
Vero_WHO_p1.0	NW_023666073	16,563,865 - 16,584,962 (-)	NCBI

Sequence:

show sequence

CCCGCCCCGCCCTTCCCGGGTCAGTGAGGGAGCGCCCGGCTCCCGCAGGCGCTCGGTCTCCGCTCATTCCTGATCCCGCGGTGGGCGCGATGGCGGGTTCTGTATTGAGGGTCGCCCGGCGGCAGCTG
AGCCAGCGTGGCGGGTCTGGAGCCCCCATCCTCCTGCGGCAGATGTTCGAGCCCGTGAGCTGCACCTACACGTACCTACTGGGTGACAGAGAATCCCGGGAGGCCGTTCTGATCGACCCGGTCCTGGA
AACAGCACCTCGGGATGCCCAACTGATCAAGGAGCTGGGGCTGCGGCTGCTGTATGCTGTGAATACCCACTGCCACGCGGACCACATTACAGGCTCGGGGCTGCTCCGTTCCCTTCTCCCTGGCTGCC
AGTCTGTCATCTCCCGCCTTAGTGGGGCCCAGGCTGACTTGCACATCGAGGATGGAGACTCCATCCGCTTCGGGCGCTTCGCCTTGGAGACCAGGGCCAGCCCTGGCCACACCCCAGGCTGTGTCACC
TTCGTCCTGAATGACCACAGCATGGCCTTCACTGGAGATGCCCTGTTGATCCGTGGGTGTGGGCGGACAGACTTCCAGCAAGGCTGTGCCAAGACCTTGTACCACTCGGTCCATGAAAAGATCTTCAC
ACTTCCAGGCGACTGTCTGATCTACCCTGCTCATGATTACCATGGGTTCACAGTGTCCACCGTGGAGGAGGAGAGGACTCTGAACCCTCGGCTCACCCGCAGCTGTGAGGAGTTTGTCAAAATCATGG
ACAACCTGAACTTGCCTAAACCTCAGCAGATAGACTTTGCTGTTCCAGCCAACATGCGCTGTGGGGTGCAGACACCGCCCCCTGCCTGATCTCACTTCTGTCAGATGCTCCCATCCAGTATTAATGCA
CTAGGGGGGAGGAGAGGGCGGCGTCCACACTGCACCTCTCCTTTCCCACCCCATGCCCGAACCGCAGCCCCTGGAGCTTCCTAAATAAAACTTTTTTTAACATGA

hide sequence

RefSeq Acc Id:

XM_007997020 ⟹ XP_007995211

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
ChlSab1.1	6	37,024,015 - 37,045,438 (-)	NCBI
Vero_WHO_p1.0	NW_023666073	16,563,865 - 16,584,907 (-)	NCBI

Sequence:

show sequence

GAGGGGACTACTGGGCGCTAGGCGGCAGCAAGGACGGAACTCCGGGGTCTCTTAATAGGGAGAGATCCGGGGGACCCACGCCTGCATCTTGCGGAAAGCGGGGTGGAGGTTTAGGGCTGGACTCTTGG
GTCCTTTAAAGATGTTCGAGCCCGTGAGCTGCACCTACACGTACCTACTGGGTGACAGAGAATCCCGGGAGGCCGTTCTGATCGACCCGGTCCTGGAAACAGCACCTCGGGATGCCCAACTGATCAAG
GAGCTGGGGCTGCGGCTGCTGTATGCTGTGAATACCCACTGCCACGCGGACCACATTACAGGCTCGGGGCTGCTCCGTTCCCTTCTCCCTGGCTGCCAGTCTGTCATCTCCCGCCTTAGTGGGGCCCA
GGCTGACTTGCACATCGAGGATGGAGACTCCATCCGCTTCGGGCGCTTCGCCTTGGAGACCAGGGCCAGCCCTGGCCACACCCCAGGCTGTGTCACCTTCGTCCTGAATGACCACAGCATGGCCTTCA
CTGGAGATGCCCTGTTGATCCGTGGGTGTGGGCGGACAGACTTCCAGCAAGGCTGTGCCAAGACCTTGTACCACTCGGTCCATGAAAAGATCTTCACACTTCCAGGCGACTGTCTGATCTACCCTGCT
CATGATTACCATGGGTTCACAGTGTCCACCGTGGAGGAGGAGAGGACTCTGAACCCTCGGCTCACCCGCAGCTGTGAGGAGTTTGTCAAAATCATGGACAACCTGAACTTGCCTAAACCTCAGCAGAT
AGACTTTGCTGTTCCAGCCAACATGCGCTGTGGGGTGCAGACACCGCCCCCTGCCTGATCTCACTTCTGTCAGATGCTCCCATCCAGTATTAATGCACTAGGGGGGAGGAGAGGGCGGCGTCCACACT
GCACCTCTCCTTTCCCACCCCATGCCCGAACCGCAGCCCCTGGAGCTTCCTAAATAAAACTTTTTTTAACATGA

hide sequence


Protein RefSeqs	XP_007995210	(Get FASTA)	NCBI Sequence Viewer
	XP_007995211	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCSAP00000014644
	ENSCSAP00000014644.1

RefSeq Acc Id:	XP_007995210 ⟸ XM_007997019
- Peptide Label:	isoform X1
- UniProtKB:	A0A0D9S1A5 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_007995211 ⟸ XM_007997020
- Peptide Label:	isoform X2

Ensembl Acc Id:

ENSCSAP00000014644 ⟸ ENSCSAT00000001434

Database	Acc Id	Source(s)
Ensembl Genes	ENSCSAG00000003404	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCSAT00000001434.1	UniProtKB/TrEMBL
Gene3D-CATH	3.60.15.10	UniProtKB/TrEMBL
InterPro	Metallo-B-lactamas	UniProtKB/TrEMBL
	Mito_Persulfide_Diox	UniProtKB/TrEMBL
	POD-like_MBL-fold	UniProtKB/TrEMBL
	RibonucZ/Hydroxyglut_hydro	UniProtKB/TrEMBL
KEGG Report	csab:103234782	UniProtKB/TrEMBL
NCBI Gene	ETHE1	ENTREZGENE
PANTHER	PERSULFIDE DIOXYGENASE ETHE1	UniProtKB/TrEMBL
	PERSULFIDE DIOXYGENASE ETHE1, MITOCHONDRIAL	UniProtKB/TrEMBL
Pfam	Lactamase_B	UniProtKB/TrEMBL
SMART	Lactamase_B	UniProtKB/TrEMBL
Superfamily-SCOP	SSF56281	UniProtKB/TrEMBL
UniProt	A0A0D9S1A5	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailable


InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailable


Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
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MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable

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