Rell1 (RELT-like 1) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: Rell1 (RELT-like 1) Rattus norvegicus
Analyze
Symbol: Rell1
Name: RELT-like 1
RGD ID: 1307468
Description: Predicted to be involved in positive regulation of p38MAPK cascade. Predicted to be located in microtubule cytoskeleton. Predicted to be active in plasma membrane. Orthologous to human RELL1 (RELT like 1); INTERACTS WITH 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine; 3,3',5,5'-tetrabromobisphenol A.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC289635; RELT-like protein 1; RGD1307468; similar to expressed sequence AA536743
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81444,672,121 - 44,732,081 (+)NCBIGRCr8
mRatBN7.21444,318,640 - 44,378,541 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1444,303,009 - 44,378,500 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1444,681,475 - 44,730,263 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01445,981,404 - 46,030,193 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01444,461,557 - 44,510,341 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01445,982,244 - 46,041,907 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1445,982,244 - 46,041,866 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01445,787,180 - 45,847,126 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41447,179,973 - 47,229,627 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11447,185,966 - 47,200,193 (-)NCBI
Celera1443,460,106 - 43,515,377 (+)NCBICelera
Cytogenetic Map14p11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932   PMID:28688764  


Genomics

Comparative Map Data
Rell1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81444,672,121 - 44,732,081 (+)NCBIGRCr8
mRatBN7.21444,318,640 - 44,378,541 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1444,303,009 - 44,378,500 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1444,681,475 - 44,730,263 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01445,981,404 - 46,030,193 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01444,461,557 - 44,510,341 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01445,982,244 - 46,041,907 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1445,982,244 - 46,041,866 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01445,787,180 - 45,847,126 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41447,179,973 - 47,229,627 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11447,185,966 - 47,200,193 (-)NCBI
Celera1443,460,106 - 43,515,377 (+)NCBICelera
Cytogenetic Map14p11NCBI
RELL1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38437,586,304 - 37,686,376 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl437,590,800 - 37,686,376 (-)EnsemblGRCh38hg38GRCh38
GRCh37437,592,426 - 37,687,998 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36437,268,817 - 37,364,394 (-)NCBINCBI36Build 36hg18NCBI36
Celera438,031,897 - 38,127,507 (-)NCBICelera
Cytogenetic Map4p14NCBI
HuRef436,916,955 - 37,012,394 (-)NCBIHuRef
CHM1_1437,591,419 - 37,687,547 (-)NCBICHM1_1
T2T-CHM13v2.0437,559,941 - 37,655,575 (-)NCBIT2T-CHM13v2.0
Rell1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39564,047,296 - 64,126,165 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl564,066,240 - 64,126,240 (-)EnsemblGRCm39 Ensembl
GRCm38563,889,337 - 63,969,020 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl563,908,897 - 63,968,897 (-)EnsemblGRCm38mm10GRCm38
MGSCv37564,300,137 - 64,360,136 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36564,188,667 - 64,248,001 (-)NCBIMGSCv36mm8
Celera561,200,867 - 61,260,171 (-)NCBICelera
Cytogenetic Map5C3.1NCBI
cM Map532.8NCBI
Rell1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554439,460,682 - 9,526,986 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554439,461,570 - 9,526,986 (+)NCBIChiLan1.0ChiLan1.0
RELL1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2337,799,868 - 37,873,862 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1437,992,302 - 38,066,195 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0431,939,962 - 32,013,856 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1437,798,632 - 37,869,421 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl437,798,632 - 37,869,421 (-)Ensemblpanpan1.1panPan2
RELL1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1374,493,133 - 74,555,976 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl374,489,571 - 74,554,086 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha377,040,360 - 77,103,166 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0375,274,403 - 75,336,739 (+)NCBIROS_Cfam_1.0
UMICH_Zoey_3.1374,540,353 - 74,603,128 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0374,687,392 - 74,750,146 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0375,065,069 - 75,128,089 (+)NCBIUU_Cfam_GSD_1.0
Rell1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440528540,602,899 - 40,670,798 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364825,625,349 - 5,695,360 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364825,626,563 - 5,695,320 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RELL1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl829,118,514 - 29,190,565 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1829,118,511 - 29,190,591 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2830,533,593 - 30,568,840 (-)NCBISscrofa10.2Sscrofa10.2susScr3
RELL1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12712,602,526 - 12,673,000 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2712,602,540 - 12,676,013 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604759,017,806 - 59,097,774 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Rell1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248406,207,394 - 6,268,205 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248406,207,560 - 6,268,193 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Rell1
202 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:66
Count of miRNA genes:55
Interacting mature miRNAs:63
Transcripts:ENSRNOT00000002984
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2313089Bss81Bone structure and strength QTL 813.40.0001body length (VT:0001256)body length, nose to rump (CMO:0000079)143766971982669719Rat
1581500Renag1Renal agenesis QTL 1kidney development trait (VT:0000527)percentage of study population developing unilateral renal agenesis during a period of time (CMO:0000940)14817066868298175Rat
10755459Coatc15Coat color QTL 150.01681coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)141983694464836944Rat
70214Niddm28Non-insulin dependent diabetes mellitus QTL 284.06blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)143999825175582726Rat
1300154Bp189Blood pressure QTL 1893.04arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)143088377768757901Rat
70187Pancm5Pancreatic morphology QTL 516.7pancreas mass (VT:0010144)pancreas weight to body weight ratio (CMO:0000630)143032009280829842Rat
631523Pia13Pristane induced arthritis QTL 133.3joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)144079346098037301Rat
1358296Ael3Aortic elastin QTL 33.70.00051aorta elastin amount (VT:0003905)aortic elastin14826709053267090Rat
2313100Bss82Bone structure and strength QTL 8230.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)143766971982669719Rat
7387267Uae42Urinary albumin excretion QTL 420.61urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)142216796767167967Rat
631839Niddm37Non-insulin dependent diabetes mellitus QTL 373.37blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)141103062295876975Rat
2313397Coatc1Coat color QTL1coat/hair pigmentation trait (VT:0010463)coat/hair color measurement (CMO:0001808)141854133263541332Rat
2313048Bss84Bone structure and strength QTL 843.10.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)143766971982669719Rat
1300136Rf22Renal function QTL 223.9renal blood flow trait (VT:2000006)absolute change in renal vascular resistance (CMO:0001900)144226252995023211Rat
2302045Pia39Pristane induced arthritis QTL 394.90.001blood immunoglobulin amount (VT:0002460)serum immunoglobulin G2a level (CMO:0002116)14826709053267090Rat
738037Hcas6Hepatocarcinoma susceptibility QTL 62.93liver integrity trait (VT:0010547)liver nonremodeling tumorous lesion volume to total liver volume ratio (CMO:0001464)143905723783368335Rat
2313084Bss83Bone structure and strength QTL 832.90.0001tibia size trait (VT:0100001)tibia midshaft endosteal cross-sectional area (CMO:0001716)143766971982669719Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31

Sequence


Ensembl Acc Id: ENSRNOT00000002984   ⟹   ENSRNOP00000002984
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1444,349,668 - 44,378,500 (+)Ensembl
Rnor_6.0 Ensembl1445,982,311 - 46,030,937 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000076611   ⟹   ENSRNOP00000068011
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1444,338,250 - 44,378,498 (+)Ensembl
Rnor_6.0 Ensembl1446,001,849 - 46,041,866 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000076881   ⟹   ENSRNOP00000068475
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1444,318,658 - 44,378,498 (+)Ensembl
Rnor_6.0 Ensembl1445,982,244 - 46,040,373 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000099775   ⟹   ENSRNOP00000093010
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1444,303,009 - 44,378,500 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000119266   ⟹   ENSRNOP00000085317
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1444,350,013 - 44,378,500 (+)Ensembl
RefSeq Acc Id: NM_001113776   ⟹   NP_001107248
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81444,672,296 - 44,720,927 (+)NCBI
mRatBN7.21444,318,711 - 44,367,345 (+)NCBI
Rnor_6.01445,982,311 - 46,030,937 (+)NCBI
Rnor_5.01445,787,180 - 45,847,126 (+)NCBI
RGSC_v3.41447,179,973 - 47,229,627 (-)RGD
Celera1443,460,106 - 43,515,377 (+)RGD
Sequence:
RefSeq Acc Id: XM_006250998   ⟹   XP_006251060
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81444,672,121 - 44,732,081 (+)NCBI
mRatBN7.21444,318,640 - 44,378,519 (+)NCBI
Rnor_6.01445,982,244 - 46,041,907 (+)NCBI
Rnor_5.01445,787,180 - 45,847,126 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039091719   ⟹   XP_038947647
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81444,672,121 - 44,732,081 (+)NCBI
mRatBN7.21444,318,640 - 44,378,541 (+)NCBI
RefSeq Acc Id: NP_001107248   ⟸   NM_001113776
- Peptide Label: precursor
- UniProtKB: B0BNL7 (UniProtKB/TrEMBL),   A0A096MJ67 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006251060   ⟸   XM_006250998
- Peptide Label: isoform X1
- UniProtKB: B0BNL7 (UniProtKB/TrEMBL),   A0A096MJ67 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000002984   ⟸   ENSRNOT00000002984
Ensembl Acc Id: ENSRNOP00000068475   ⟸   ENSRNOT00000076881
Ensembl Acc Id: ENSRNOP00000068011   ⟸   ENSRNOT00000076611
RefSeq Acc Id: XP_038947647   ⟸   XM_039091719
- Peptide Label: isoform X1
- UniProtKB: B0BNL7 (UniProtKB/TrEMBL),   A0A096MJ67 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000085317   ⟸   ENSRNOT00000119266
Ensembl Acc Id: ENSRNOP00000093010   ⟸   ENSRNOT00000099775

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-B0BNL7-F1-model_v2 AlphaFold B0BNL7 1-272 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13699325
Promoter ID:EPDNEW_R9848
Type:initiation region
Name:Rell1_1
Description:RELT-like 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01445,982,300 - 45,982,360EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1307468 AgrOrtholog
BioCyc Gene G2FUF-15695 BioCyc
Ensembl Genes ENSRNOG00000002192 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000002984.7 UniProtKB/TrEMBL
  ENSRNOT00000076611.2 UniProtKB/TrEMBL
  ENSRNOT00000076881.3 UniProtKB/TrEMBL
  ENSRNOT00000099775.1 UniProtKB/TrEMBL
  ENSRNOT00000119266.1 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7932431 IMAGE-MGC_LOAD
InterPro RELL1 UniProtKB/TrEMBL
  TNFR_19L UniProtKB/TrEMBL
KEGG Report rno:289635 UniProtKB/TrEMBL
MGC_CLONE MGC:188531 IMAGE-MGC_LOAD
NCBI Gene 289635 ENTREZGENE
PANTHER PTHR31037 UniProtKB/TrEMBL
  RELT-LIKE PROTEIN 1 UniProtKB/TrEMBL
Pfam RELT UniProtKB/TrEMBL
PhenoGen Rell1 PhenoGen
RatGTEx ENSRNOG00000002192 RatGTEx
UniProt A0A096MJ67 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6A1E4_RAT UniProtKB/TrEMBL
  A0A8I6AI49_RAT UniProtKB/TrEMBL
  B0BNL7 ENTREZGENE, UniProtKB/TrEMBL
  F7FL97_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-03-07 Rell1  RELT-like 1  RGD1307468_predicted  similar to expressed sequence AA536743 (predicted)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-01-20 RGD1307468_predicted  similar to expressed sequence AA536743 (predicted)  LOC289635_predicted    Symbol and Name status set to approved 1331353 APPROVED
2005-01-12 LOC289635_predicted  similar to expressed sequence AA536743 (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL