Znrf2 (zinc and ring finger 2) - Rat Genome Database

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Gene: Znrf2 (zinc and ring finger 2) Rattus norvegicus
Analyze
Symbol: Znrf2
Name: zinc and ring finger 2
RGD ID: 1306645
Description: Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in positive regulation of autophagosome-lysosome fusion; proteasome-mediated ubiquitin-dependent protein catabolic process; and protein K48-linked ubiquitination. Predicted to be located in cytoplasmic vesicle membrane; nuclear lumen; and plasma membrane. Predicted to be part of protein-containing complex. Predicted to be active in cytoplasm; intracellular membrane-bounded organelle; and membrane. Orthologous to human ZNRF2 (zinc and ring finger 2); INTERACTS WITH 1,3-dinitrobenzene; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: E3 ubiquitin-protein ligase ZNRF2; LOC362367; zinc and ring finger 1; zinc and ring finger 2, E3 ubiquitin protein ligase; Znrf1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8485,274,626 - 85,358,083 (+)NCBIGRCr8
mRatBN7.2483,950,406 - 84,032,676 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl483,949,309 - 84,027,818 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx489,171,393 - 89,248,667 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0484,946,808 - 85,024,087 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0483,361,475 - 83,438,741 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0485,009,350 - 85,090,914 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl485,009,350 - 85,090,914 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04149,666,569 - 149,684,037 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.04149,717,446 - 149,748,158 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4483,224,883 - 83,361,095 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1483,509,523 - 83,644,305 (+)NCBI
Celera478,818,136 - 78,895,341 (+)NCBICelera
Cytogenetic Map4q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:19028597   PMID:22797923   PMID:33992580  


Genomics

Comparative Map Data
Znrf2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8485,274,626 - 85,358,083 (+)NCBIGRCr8
mRatBN7.2483,950,406 - 84,032,676 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl483,949,309 - 84,027,818 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx489,171,393 - 89,248,667 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0484,946,808 - 85,024,087 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0483,361,475 - 83,438,741 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0485,009,350 - 85,090,914 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl485,009,350 - 85,090,914 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04149,666,569 - 149,684,037 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.04149,717,446 - 149,748,158 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4483,224,883 - 83,361,095 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1483,509,523 - 83,644,305 (+)NCBI
Celera478,818,136 - 78,895,341 (+)NCBICelera
Cytogenetic Map4q24NCBI
ZNRF2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38730,284,597 - 30,367,689 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl730,284,597 - 30,367,689 (+)EnsemblGRCh38hg38GRCh38
GRCh37730,324,213 - 30,407,305 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36730,290,448 - 30,373,833 (+)NCBINCBI36Build 36hg18NCBI36
Build 34730,097,162 - 30,180,547NCBI
Celera730,313,247 - 30,396,631 (+)NCBICelera
Cytogenetic Map7p14.3NCBI
HuRef730,206,083 - 30,289,579 (+)NCBIHuRef
CHM1_1730,324,010 - 30,407,338 (+)NCBICHM1_1
T2T-CHM13v2.0730,422,290 - 30,505,386 (+)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v2730,373,689 - 30,457,078 (+)NCBI
Znrf2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39654,793,901 - 54,867,209 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl654,793,901 - 54,870,485 (+)EnsemblGRCm39 Ensembl
GRCm38654,816,916 - 54,890,224 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl654,816,916 - 54,893,500 (+)EnsemblGRCm38mm10GRCm38
MGSCv37654,766,910 - 54,840,218 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36654,746,494 - 54,819,314 (+)NCBIMGSCv36mm8
Celera655,350,483 - 55,423,786 (+)NCBICelera
Cytogenetic Map6B3NCBI
cM Map627.15NCBI
Znrf2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495541031,550,519 - 31,628,084 (+)NCBIChiLan1.0ChiLan1.0
ZNRF2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2635,111,931 - 35,194,163 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1783,436,675 - 83,518,890 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0730,922,235 - 31,006,950 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
ZNRF2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11443,029,270 - 43,123,292 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1442,462,394 - 42,557,203 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01442,972,032 - 43,067,204 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1442,972,047 - 43,059,124 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11443,088,065 - 43,183,149 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01442,767,167 - 42,862,262 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01443,125,367 - 43,220,433 (+)NCBIUU_Cfam_GSD_1.0
Znrf2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440511887,377,709 - 87,469,585 (+)NCBIHiC_Itri_2
SpeTri2.0NW_0049364786,589,440 - 6,681,315 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ZNRF2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1842,549,846 - 42,651,807 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11842,550,571 - 42,651,914 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21846,866,273 - 47,037,101 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ZNRF2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12127,930,382 - 28,097,754 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2128,014,791 - 28,096,703 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604276,599,517 - 76,687,514 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Znrf2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624739385,359 - 497,597 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624739360,118 - 497,626 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Znrf2
393 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1683
Count of miRNA genes:359
Interacting mature miRNAs:509
Transcripts:ENSRNOT00000072271
Prediction methods:Microtar, Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1358352Srcrt3Stress Responsive Cort QTL 32.29blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)438465774146803430Rat
1549843Bw53Body weight QTL 530.0001body mass (VT:0001259)body weight gain (CMO:0000420)461697658103194791Rat
61445Strs3Sensitivity to stroke QTL 33cerebrum integrity trait (VT:0010549)post-insult time to onset of cerebrovascular lesion (CMO:0002343)44043338885433388Rat
6893678Bw108Body weight QTL 1082.60.006body mass (VT:0001259)body weight (CMO:0000012)44345797688457976Rat
10755501Bp390Blood pressure QTL 3902.5arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)426775591168368347Rat
1357342Bw40Body weight QTL 400.001body mass (VT:0001259)body weight (CMO:0000012)476647384117676292Rat
631556Bp135Blood pressure QTL 1350.017arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)478881294117676292Rat
1358363Sradr3Stress Responsive Adrenal Weight QTL 36.19adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)457486946102486946Rat
61330Eau1Experimental allergic uveoretinitis QTL 10.0003uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)470362013132642728Rat
70167Bw22Body weight QTL 223.1body mass (VT:0001259)body weight (CMO:0000012)476647384117676292Rat
1549839Bw52Body weight QTL 520.0001body mass (VT:0001259)body weight gain (CMO:0000420)461697658115089733Rat
70177Xhs1X-ray hypersensitivity QTL 125.1intestine integrity trait (VT:0010554)post-insult time to onset of moribundity (CMO:0001896)482798864152731274Rat
724522Bp146Blood pressure QTL 1462.20.0021arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)473630210118630210Rat
8694439Bw168Body weight QTL 1689.570.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)44043341485433414Rat
1641919Alc22Alcohol consumption QTL 220.0005drinking behavior trait (VT:0001422)ethanol drink intake rate (CMO:0001407)481192555126192555Rat
1354660Salc1Saline consumption QTL 111.26drinking behavior trait (VT:0001422)saline drink intake rate (CMO:0001627)444463908148090542Rat
2300179Bmd50Bone mineral density QTL 505.90.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)460928534105928534Rat
1298082Stresp4Stress response QTL 4blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)450119848146803430Rat
70192BpQTLcluster5Blood pressure QTL cluster 54.183arterial blood pressure trait (VT:2000000)absolute change in mean arterial blood pressure (CMO:0000533)462933508114921294Rat
61364Iddm2Insulin dependent diabetes mellitus QTL 2blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)478885890102684881Rat
1300139Hrtrt6Heart rate QTL 62.85heart pumping trait (VT:2000009)heart rate (CMO:0000002)439524264116179656Rat
70200Alc18Alcohol consumption QTL 189.2drinking behavior trait (VT:0001422)ethanol intake volume to total fluid intake volume ratio (CMO:0001591)456647873149491524Rat
1578657Bss12Bone structure and strength QTL 128.9femur morphology trait (VT:0000559)femoral neck cross-sectional area (CMO:0001697)460220938105220938Rat
1578658Bss13Bone structure and strength QTL 138femur strength trait (VT:0010010)femoral neck polar moment of inertia (CMO:0001670)460220938105220938Rat
2316958Gluco58Glucose level QTL 5810blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)411320076180699135Rat
6478684Anxrr30Anxiety related response QTL 300.00087defecation behavior trait (VT:0010462)defecation rate (CMO:0000998)462753847107753847Rat
2302051Pia28Pristane induced arthritis QTL 285.30.001blood autoantibody amount (VT:0003725)serum immunoglobulin G-type rheumatoid factor level relative to an arbitrary reference serum (CMO:0002112)473630210118630210Rat
2306794Ean2Experimental allergic neuritis QTL 26.4nervous system integrity trait (VT:0010566)IFNG-secreting splenocyte count (CMO:0002122)48342841995853334Rat
738009Sach4Saccharine consumption QTL 44.90.000016consumption behavior trait (VT:0002069)saccharin intake volume to total fluid intake volume ratio (CMO:0001601)459948935154902892Rat
631261Tcas3Tongue tumor susceptibility QTL 36.88tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)41081417091360527Rat
2312567Glom19Glomerulus QTL 191.90.006kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)445456990146803430Rat
738015Pia9Pristane induced arthritis QTL 94.50.048joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)480694870125694870Rat
6478772Anxrr49Anxiety related response QTL 490.15488defecation behavior trait (VT:0010462)defecation rate (CMO:0000998)462753847107753847Rat
631646Stl4Serum triglyceride level QTL 46.50.0001blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)473169846132642728Rat
2312569Pur19Proteinuria QTL 193.40.001urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)46588210796130297Rat
8655961Kidm43Kidney mass QTL 4318kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)436303261103194984Rat
1354612Foco1Food consumption QTL 18.87eating behavior trait (VT:0001431)food intake rate (CMO:0000427)444463908148090542Rat
634344Hcar7Hepatocarcinoma resistance QTL 77.8liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)470808386115808386Rat
2303168Bp330Blood pressure QTL 3304.250.017arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)45214602146446691Rat
738031Alc14Alcohol consumption QTL 147.60.00003consumption behavior trait (VT:0002069)ethanol drink intake rate to body weight ratio (CMO:0001616)459948935154902892Rat
1576316Ept5Estrogen-induced pituitary tumorigenesis QTL 53.8pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)483428419177635233Rat
631662Hcar2Hepatocarcinoma resistance QTL 23.10.0003liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)478878504123878504Rat
1576305Emca6Estrogen-induced mammary cancer QTL 65.8mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)444463720155883716Rat
61418Pia5Pristane induced arthritis QTL 54.5joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)462277855128289560Rat
631651Bp124Blood pressure QTL 1243arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)462879517107879517Rat
738016Alc16Alcohol consumption QTL 163.60.00015consumption behavior trait (VT:0002069)ethanol drink intake rate to body weight ratio (CMO:0001616)459948935154902892Rat
1558651Swd3Spike wave discharge measurement QTL 34.620.000024brain electrophysiology trait (VT:0010557)brain spike-and-wave discharge frequency (CMO:0001742)45843213392991462Rat
1641833Alc21Alcohol consumption QTL 218.60.0001drinking behavior trait (VT:0001422)ethanol drink intake rate (CMO:0001407)456698790126192555Rat
2306899Bp338Blood pressure QTL 3380.071arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)481006124120102625Rat
631546Bp86Blood pressure QTL 863.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)45711443291360801Rat
631674Iddm14Insulin dependent diabetes mellitus QTL 14blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)464528739157573521Rat
6478743Anxrr40Anxiety related response QTL 400.83076defecation behavior trait (VT:0010462)defecation rate (CMO:0000998)462753847107753847Rat
7394826Bw126Body weight QTL 1260.002body mass (VT:0001259)body weight gain (CMO:0000420)46293326987483707Rat
12798520Anxrr55Anxiety related response QTL 554.450.01locomotor behavior trait (VT:0001392)number of rearing movements with lid-pushing in an experimental apparatus (CMO:0002715)432583980114627242Rat

Markers in Region
RH130994  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2484,027,506 - 84,027,721 (+)MAPPERmRatBN7.2
Rnor_6.0485,090,603 - 85,090,817NCBIRnor6.0
Rnor_5.04149,747,847 - 149,748,061UniSTSRnor5.0
RGSC_v3.4483,360,784 - 83,360,998UniSTSRGSC3.4
Celera478,895,030 - 78,895,244UniSTS
RH 3.4 Map4522.6UniSTS
Cytogenetic Map4q24UniSTS
AA875513  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2484,023,699 - 84,023,909 (+)MAPPERmRatBN7.2
Rnor_6.0485,086,796 - 85,087,005NCBIRnor6.0
Rnor_5.04149,744,040 - 149,744,249UniSTSRnor5.0
RGSC_v3.4483,356,977 - 83,357,186UniSTSRGSC3.4
Celera478,891,223 - 78,891,432UniSTS
RH 3.4 Map4525.2UniSTS
Cytogenetic Map4q24UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31

Sequence


Ensembl Acc Id: ENSRNOT00000072271   ⟹   ENSRNOP00000066872
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl483,949,309 - 84,027,818 (+)Ensembl
Rnor_6.0 Ensembl485,009,350 - 85,090,914 (+)Ensembl
RefSeq Acc Id: NM_001108628   ⟹   NP_001102098
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8485,280,702 - 85,358,083 (+)NCBI
mRatBN7.2483,950,430 - 84,027,810 (+)NCBI
Rnor_6.0485,009,350 - 85,090,914 (+)NCBI
Rnor_5.04149,666,569 - 149,684,037 (+)NCBI
Rnor_5.04149,717,446 - 149,748,158 (+)NCBI
RGSC_v3.4483,224,883 - 83,361,095 (+)RGD
Celera478,818,136 - 78,895,341 (+)RGD
Sequence:
RefSeq Acc Id: XM_039107798   ⟹   XP_038963726
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8485,274,626 - 85,351,279 (+)NCBI
mRatBN7.2483,950,415 - 84,022,807 (+)NCBI
RefSeq Acc Id: XR_010065675
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8485,274,626 - 85,349,472 (+)NCBI
Protein Sequences
Protein RefSeqs NP_001102098 (Get FASTA)   NCBI Sequence Viewer  
  XP_038963726 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDL88107 (Get FASTA)   NCBI Sequence Viewer  
  EDL88108 (Get FASTA)   NCBI Sequence Viewer  
  EDL88109 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000066872.2
RefSeq Acc Id: NP_001102098   ⟸   NM_001108628
- UniProtKB: M0RBD9 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000066872   ⟸   ENSRNOT00000072271
RefSeq Acc Id: XP_038963726   ⟸   XM_039107798
- Peptide Label: isoform X1
- UniProtKB: M0RBD9 (UniProtKB/TrEMBL)
Protein Domains
RING-type

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-M0RBD9-F1-model_v2 AlphaFold M0RBD9 1-245 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13693068
Promoter ID:EPDNEW_R3593
Type:initiation region
Name:Znrf2_1
Description:zinc and ring finger 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0485,009,291 - 85,009,351EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1306645 AgrOrtholog
BioCyc Gene G2FUF-44751 BioCyc
Ensembl Genes ENSRNOG00000049057 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000072271.2 UniProtKB/TrEMBL
Gene3D-CATH 3.30.40.10 UniProtKB/TrEMBL
  Classic Zinc Finger UniProtKB/TrEMBL
InterPro Znf_RING UniProtKB/TrEMBL
  Znf_RING/FYVE/PHD UniProtKB/TrEMBL
  ZNRF_ubiq-protein_ligase UniProtKB/TrEMBL
KEGG Report rno:362367 UniProtKB/TrEMBL
NCBI Gene 362367 ENTREZGENE
PANTHER E3 UBIQUITIN-PROTEIN LIGASE ZNRF1-LIKE PROTEIN UniProtKB/TrEMBL
  E3 UBIQUITIN-PROTEIN LIGASE ZNRF2 UniProtKB/TrEMBL
Pfam zf-RING_2 UniProtKB/TrEMBL
PhenoGen Znrf2 PhenoGen
PROSITE ZF_RING_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000049057 RatGTEx
SMART RING UniProtKB/TrEMBL
Superfamily-SCOP RING/U-box UniProtKB/TrEMBL
UniProt A6K0V9_RAT UniProtKB/TrEMBL
  M0RBD9 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-08-18 Znrf2  zinc and ring finger 2  Znrf2  zinc and ring finger 2, E3 ubiquitin protein ligase  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2015-12-01 Znrf2  zinc and ring finger 2, E3 ubiquitin protein ligase  Znrf2  zinc and ring finger 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2010-05-05 Znrf2  zinc and ring finger 2  Znrf1  zinc and ring finger 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Znrf1  zinc and ring finger 1   Znrf1_predicted  zinc and ring finger 1 (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Znrf1_predicted  zinc and ring finger 1 (predicted)      Symbol and Name status set to approved 70820 APPROVED