Ean2 QTL Report (Rattus norvegicus) - Rat Genome Database
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QTL: Ean2 (Experimental allergic neuritis QTL 2) Rattus norvegicus

Symbol: Ean2
Name: Experimental allergic neuritis QTL 2
RGD ID: 2306794
Trait: nervous system integrity trait   (VT:0010566)    
Measurement Type: IFNG-secreting splenocyte count   (CMO:0002122)    
LOD Score: 6.4
P Value: Not Available
Variance: Not Available
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.0484,475,257 - 97,479,149RGD_MAPPER_PIPELINERnor6.0
Rnor_5.04149,135,946 - 162,264,045RGDRnor5.0
RGSC_v3.4482,700,691 - 96,313,512RGDRGSC3.4
Cross Type: intercross
Strains Crossed: Kini:DA,PVG-G12 
JBrowse: View Region in Genome Browser (JBrowse)
Model



Disease Annotations     Click to see Annotation Detail View

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
Experimental Data Annotations     Click to see Annotation Detail View

Clinical Measurement

Experimental Condition

Measurement Method

Vertebrate Trait

Rat Strain

References

References - curated
1. Huberle A, etal., J Immunol. 2009 Apr 1;182(7):4432-8.
Related QTLs

Related QTL Description Reference
Cia3 maps to same region RGD:2306769


Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
68332Pde1cphosphodiesterase 1C48635976286925044Rat
70547Crhr2corticotropin releasing hormone receptor 248528637185329374Rat
2141Aqp1aquaporin 148555150385563683Rat
2038Adcyap1r1ADCYAP receptor type I48566280985711696Rat
631345Abcg2ATP binding cassette subfamily G member 248876544188890268Rat
2688Ghrhrgrowth hormone releasing hormone receptor48558732185602389Rat
620960Hint1-ps1histidine triad nucleotide binding protein 1, pseudogene 149340566593406239Rat
628647Ppp1r17protein phosphatase 1, regulatory subunit 1748627513086292435Rat
1304876Ggctgamma-glutamyl cyclotransferase48518664485192857Rat
735071RSA-14-44RSA-14-44 protein49683188096833252Rat
3729Sncasynuclein alpha49078241290883236Rat
69251Hpgdshematopoietic prostaglandin D synthase49594535695970666Rat
68368Grid2glutamate ionotropic receptor delta type subunit 249406811295476864Rat
1307803Herc3HECT and RLD domain containing E3 ubiquitin protein ligase 348907867089169150Rat
1307592Lin28clin-28 homolog C (C. elegans)49737372397376654Rat
1306645Znrf2zinc and ring finger 248500935085090914Rat
708559Wipf3WAS/WASL interacting protein family, member 348459630584676775Rat
1311705Fkbp14FKBP prolyl isomerase 1448475362884768314Rat
1308501Ppm1kprotein phosphatase, Mg2+/Mn2+ dependent, 1K48869439588721374Rat
1309807Fam13afamily with sequence similarity 13, member A48918318089281282Rat
1312013Nt5c3a5'-nucleotidase, cytosolic IIIA48723832587281234Rat
1311080Ndnfneuron-derived neurotrophic factor49652883096565780Rat
1310809Lancl2LanC like 248852421288565113Rat
1308655Lsm5LSM5 homolog, U6 small nuclear RNA and mRNA degradation associated48701600387019219Rat
1549777Vom1r71vomeronasal 1 receptor 7148760830187609203Rat
1311589Prr15proline rich 1548447883984481885Rat
1306494Vopp1VOPP1 WW domain binding protein48844106788515141Rat
1307856Garsglycyl-tRNA synthetase48523512285276085Rat
1310317Kbtbd2kelch repeat and BTB domain containing 248708875987111576Rat
1309640Smarcad1SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1`49588402095945248Rat
1561131Itprid1ITPR interacting domain containing 148608041286233808Rat
1563940Plekha8pleckstrin homology domain containing A848477029484820887Rat
1564615Avl9AVL9 cell migration associated48702647187070738Rat
1560028RGD1560028similar to RIKEN cDNA C130060K24 gene49625263496331555Rat
1565731Ccser1coiled-coil serine-rich protein 149123588592516800Rat
1563162LOC500148similar to 40S ribosomal protein S7 (S8)48867515288684415Rat
1549721Vom1r68vomeronasal 1 receptor 6848744099687441907Rat
1549722Vom1r69vomeronasal 1 receptor 6948745500187455909Rat
1560999Scrn1secernin 148467897884740701Rat
1359257Vom1r79vomeronasal 1 receptor 7948798186987982729Rat
1562269Nod1nucleotide-binding oligomerization domain containing 148512396585175206Rat
1549695Vom1r74vomeronasal 1 receptor 7448781474187815652Rat
1549696Vom1r86vomeronasal 1 receptor 8648827106188271969Rat
1549699Vom1r88vomeronasal 1 receptor 8848841717588424973Rat
1549700Mturnmaturin, neural progenitor differentiation regulator homolog48485434184875300Rat
1549704Vom1r78vomeronasal 1 receptor 7848794315287944069Rat
1549708Vom1r67vomeronasal 1 receptor 6748735325487354165Rat
1549709Vom1r72vomeronasal 1 receptor 7248769973287700631Rat
1549714Vom1r76vomeronasal 1 receptor 7648785274987853648Rat
1549715Vom1r73vomeronasal 1 receptor 7348775818187759098Rat
1549744Vom1r66vomeronasal 1 receptor 6648751621887517162Rat
1549746Vom1r82vomeronasal 1 receptor 8248810005288120975Rat
1549747Vom1r80vomeronasal 1 receptor 8048802603388026932Rat
1359218Vom1r77vomeronasal 1 receptor 7748787233087873247Rat
1549731Vom1r83vomeronasal 1 receptor 8348818495688185894Rat
1549732Vom1r85vomeronasal 1 receptor 8548823200988232917Rat
1549753Vom1r84vomeronasal 1 receptor 8448820695488208035Rat
1549756Vom1r87vomeronasal 1 receptor 8748832806188328969Rat
1549757Fkbp9FKBP prolyl isomerase 948716751487234198Rat
1564699RGD1564699similar to High mobility group protein 1 (HMG-1)49731964797320210Rat
1549765Vom1r81vomeronasal 1 receptor 8148804826788049199Rat
1560845Vom1r-ps73vomeronasal 1 receptor pseudogene 7348813694788137481Rat
1587188LOC502787similar to eukaryotic translation initiation factor 4, gamma 1 isoform a49716979697172124Rat
1587189LOC502786similar to non-POU domain containing, octamer-binding49573772695739122Rat
1587190Vom1r-ps74vomeronasal 1 receptor pseudogene 7448830404088304934Rat
1559612Tigd2tigger transposable element derived 248953541889538535Rat
1565524PyurfPIGY upstream reading frame48858424288587877Rat
1587248Mmrn1multimerin 149097753791038747Rat
1587249LOC500149similar to peptidylprolyl isomerase D48897578188977049Rat
1587250LOC500147similar to tubulin, gamma 148802798188030859Rat
1584123Nap1l5nucleosome assembly protein 1-like 548914931489152511Rat
1585226LOC688782similar to Heterogeneous nuclear ribonucleoprotein A1 (Helix-destabilizing protein) (Single-strand binding protein) (hnRNP core protein A1) (HDP-1) (Topoisomerase-inhibitor suppressed)48729388987295170Rat
1562793Neurod6neuronal differentiation 648591186185915107Rat
1565171Atoh1atonal bHLH transcription factor 149549800395500098Rat
1584130Vom1r-ps70vomeronasal 1 receptor pseudogene 7048740371587404625Rat
1561739Herc6HECT and RLD domain containing E3 ubiquitin protein ligase family member 648860685188649424Rat
1565690Gprin3GPRIN family member 348969067889778302Rat
1562590Mindy4MINDY lysine 48 deubiquitinase 448542774185536264Rat
1565107RGD1565107similar to 40S ribosomal protein SA (p40) (34/67 kDa laminin receptor)48692929086930225Rat
1591097LOC689530similar to Alpha-enolase (2-phospho-D-glycerate hydro-lyase) (Non-neural enolase) (NNE) (Enolase 1)49095939790960693Rat
1585214Vom1r65vomeronasal 1 receptor 6548731273687313899Rat
1587548LOC689832similar to 60S ribosomal protein L7a49721228097212603Rat
1588732Tnip3TNFAIP3 interacting protein 349638620796490517Rat
1597087Inmtindolethylamine N-methyltransferase48538190785386203Rat
1596167Vom1r-ps72vomeronasal 1 receptor pseudogene 7248808262788083534Rat
1597453LOC689033hypothetical protein LOC68903348786013487867414Rat
1593482LOC689382hypothetical protein LOC68938248939189389415580Rat
1596849Vom1r-ps111vomeronasal 1 receptor pseudogene 11148837953488380442Rat
1588783LOC689705hypothetical protein LOC68970549564751395647912Rat
1588700Prdm5PR/SET domain 549665906296810816Rat
2316407Vom1r-ps69vomeronasal 1 receptor pseudogene 6948739024687391242Rat
2322105LOC100360451hypothetical LOC10036045148967292589677366Rat
2323070Selenot-ps1selenoprotein T, pseudogene 148745906887459615Rat
2321912LOC100360545protein phosphatase 6, catalytic subunit49105881991086295Rat
2325113LOC10035961360S ribosomal protein L12-like48521169185215864Rat
6487873LOC100912229tubulin gamma-1 chain-like48778883587790160Rat
6487167LOC100912467vomeronasal type-1 receptor A16-like48778618287787111Rat
6491577LOC100911638protein lin-28 homolog A-like49699600196996589Rat
6500991LOC100909941uncharacterized LOC10090994148491735984921988Rat
7505827LOC102550113sentrin-specific protease 6-like48967300489675631Rat
7496134LOC102551243apolipoprotein O-like48637663386380981Rat
7509699LOC102551107uncharacterized LOC10255110748561204885625087Rat
7537419LOC102554291mitochondrial import receptor subunit TOM7 homolog48478544884790480Rat
7614437LOC102553321uncharacterized LOC10255332148768817687704752Rat
7660754LOC102550873uncharacterized LOC10255087348535255685359850Rat
7644658LOC102551794uncharacterized LOC10255179448566113385669342Rat
7685582LOC102553885uncharacterized LOC10255388548473970284758303Rat
7724284LOC102550746uncharacterized LOC10255074648535254085374090Rat
7733535LOC102551170uncharacterized LOC10255117048627726086285875Rat
7722197LOC10254678360S ribosomal protein L29-like48875384288754315Rat
7703180LOC102550675uncharacterized LOC10255067548521818285228217Rat
7709956LOC102549524uncharacterized LOC10254952448954291389560993Rat
9075196LOC103692145uncharacterized LOC10369214549065339190660044Rat
9180275LOC103692135uncharacterized LOC10369213548479319484793975Rat
9156672LOC103692147glutamate receptor ionotropic, delta-2-like49301279193035216Rat
9190320LOC103692152uncharacterized LOC10369215249641918996435994Rat
9206333LOC10369214340S ribosomal protein S6 pseudogene48789085787891643Rat
9226725LOC103692137uncharacterized LOC10369213748725767687277831Rat
9287270LOC103692136uncharacterized LOC10369213648555225785560573Rat
9386529LOC10369215114-3-3 protein theta pseudogene49606030296062112Rat
9290612LOC10369214440S ribosomal protein S6 pseudogene48791551487917046Rat
9336400LOC103692146uncharacterized LOC10369214649160176691671297Rat
9264819Tshr-ps1thyroid stimulating hormone receptor, pseudogene 149344741293448194Rat
9364885LOC103695213uncharacterized LOC10369521348855770388563386Rat
9219980LOC103692134uncharacterized LOC10369213448465038984656807Rat
9438714LOC103692148developmental pluripotency-associated protein 2 pseudogene49244329392444985Rat
9408796LOC103692133uncharacterized LOC10369213348450406584529364Rat
9451639LOC103692149axoneme-associated protein mst101(2)-like49250166392502256Rat
11369402LOC108350813Ig kappa chain V-II region 26-10-like49385777393858676Rat
11450417LOC108350840uncharacterized LOC10835084049195969092027301Rat
11451272LOC108350862uncharacterized LOC10835086248988192089900021Rat
11440908LOC108350839high mobility group protein B1-like49243151792432354Rat
11424945LOC108350863uncharacterized LOC10835086348992558389927014Rat
11356528LOC108350861glyceraldehyde-3-phosphate dehydrogenase pseudogene48732965287330654Rat
11398622LOC108350811igE-binding protein-like48987273089876205Rat
11402879LOC108348089putative vomeronasal receptor-like protein 448781471187815652Rat
11405111Vom1r75vomeronasal 1 receptor 7548782755287828514Rat
11519725LOC108350812uncharacterized LOC10835081249122913591244135Rat
11481284LOC108350810proline-rich protein 36-like48552736885549162Rat

Markers in Region
The following Markers overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolExpected SizeChrStartStopSpeciesMatch
33905D4Mit1129549248403992484312Ratregion
36378D4Mgh3321248722979987230010Ratregion
35286D4Rat3715149489310694893247Ratregion
35286D4Rat3715149305978993059930Ratregion
35409D4Rat3414948643831786438507Ratregion
36978D4Rat3813949747900997479149Ratregion
36544D4Rat7716549671146996711633Ratregion
35669D4Rat3516449249012292490285Ratregion
35721D4Rat7617848631258986312786Ratregion
38262D4Rat10321648447525784475486Ratregion
40586D4Rat23122648977755289777772Ratregion
40640D4Rat17124848934178689342035Ratregion
40020D4Rat17316049414349894143659Ratregion
39520D4Rat17023748529985585300097Ratregion
42306D4Rat26614348579404985794197Ratregion
42707D4Rat23023448861453188614772Ratregion
40856D4Rat17414249580050195800642Ratregion
41586D4Rat17213349623509296235218Ratregion
43820D4Got7527349427283794273109Ratregion
43821D4Got6520248450132684501527Ratregion
60803D4Wox432549257682492577148Ratregion
60448D4Got6328848472289584723182Ratregion
60449D4Got6723848696343586963672Ratregion
60451D4Got6919348832431288324504Ratregion
60452D4Got7028849478437394784660Ratregion
60454D4Got7227549187489191875161Ratregion
60455D4Got7320549559391895594122Ratregion
60456D4Got7416349299070192990863Ratregion
60457D4Got7615548864826388648417Ratregion
60458D4Got7727849494710494947381Ratregion
60461D4Got8016549671140496711568Ratregion
60462D4Got8117749629676796296940Ratregion
62509D4Uia732548940547289405793Ratregion
1630451D4Got2609548653695086537039Ratregion
1631098D4Got21314349480164794801789Ratregion
1628883D4Got29021849278768492787901Ratregion
1629824D4Got29122648537925385379454Ratregion
1641561D4Wox3529248467618884676479Ratregion
7205950Aqp138348556105885562107Ratregion
7206014Neurod611648591353985913654Ratregion
7205888px-35f113549038977690389910Ratregion
7206492UniSTS:546664158149549822995499809Ratregion
5038892RH12739321848487497384875190Ratregion
5039208RH12757419748556327685563472Ratregion
5037053WI-1159211748708879087088906Ratregion
5031376PMC153617P199449078297890783975Ratregion
5026176RH13120519048538197185382160Ratregion
5026374RH13196118448629221486292397Ratregion
5031706AU04742120848873810588738312Ratregion
5026580RH13275718648448162384481808Ratregion
5034586BF41650114849447841094478557Ratregion
5029419Snca13049086470990864838Ratregion
5032275AI84659012148571150085711620Ratregion
5029737BE10224719448447871484478907Ratregion
5027313D4448014148591244585912585Ratregion
5032911RH13693918148458247184582650Ratregion
5025016BB38566810249549995395500054Ratregion
5033101RH13760114548639004286390186Ratregion
5030593BF41017511248639378386393894Ratregion
5025656RH12915515048723868487238833Ratregion
5028456AI4285589848889002188890118Ratregion
5053517RH14269410148524121285241312Ratregion
5053647RH14276924548968458489684828Ratregion
5056613RH14447915648727756687277721Ratregion
5056987UniSTS:23402926749078273190782997Ratregion
5057462BF41870621849103810291038319Ratregion
5057550BE09553015348469831084698462Ratregion
5055187RH14365611048888385788883966Ratregion
5056527RH14443013248467107584671206Ratregion
5056669RH14451110449344762593447728Ratregion
5055251RH14369318448915134189151524Ratregion
5058296BF38698015448591255585912708Ratregion
5049816RH13369822048467404784674266Ratregion
5053353RH14259910849189335391893460Ratregion
5050038RH13382619148527435785275778Ratregion
5043958RH13032819048953806289538251Ratregion
5043440RH13002719248475235184752542Ratregion
5040978RH12859319548851487988515073Ratregion
5043566RH13009818048553602685536205Ratregion
5045546RH13124020548482052484820728Ratregion
5048714RH13306320149588490895885474Ratregion
5046574RH13183220548509530985095513Ratregion
5045118RH13099421548509060385090817Ratregion
5046104RH13156021048475375284753961Ratregion
5046612RH13185421848914771689147933Ratregion
5046648RH13187418048749308687493265Ratregion
5049502RH13351818048858623488586413Ratregion
5049550RH13354518049656550596565684Ratregion
7191236Neurod6101448591264485913657Ratregion
5043642RH13014318248871901188719192Ratregion
5043794RH13023118048889040088890579Ratregion
5041378RH12882318448723839087238573Ratregion
5074280RH13792518848852425988524445Ratregion
5075900RH13886213748518313285183268Ratregion
5076928RH13946018048914959189149770Ratregion
5075416RH13858114048911309789114601Ratregion
5077336RH13969818848492132484922069Ratregion
5077524RH13980519948528647485286672Ratregion
5077876RH14001118048860695088607129Ratregion
5077896RH14002221348467902784679239Ratregion
5078500RH14037924048528030885280547Ratregion
5078802RH14056019048486255484862743Ratregion
5071978RH13539421448552746085527673Ratregion
5071978RH13539421448552633685527673Ratregion
5074484RH13804316149547811895478278Ratregion
5066844AU04811727649567319195673444Ratregion
5068790AU0469298749226192492262010Ratregion
5060178BF40062924849589140495891651Ratregion
5062150BE10626616348553365985533821Ratregion
5063854BE12007216648529408685294251Ratregion
5060972BF40157915148636979286369942Ratregion
5063082BF39830717448856533488565507Ratregion
5066336PMC153617P210549078245490782558Ratregion
5066426AU04836324349103512491035366Ratregion
5066554AU04828813748982581989825955Ratregion
5086339AA87551321048508679685087005Ratregion
5087201AI22947118148518074485180924Ratregion
5087899Grid29649544136895441463Ratregion
5087897Grid212849544126995441396Ratregion
5089555AU04922517249534582795345998Ratregion
5088621AU04867824848472811484728361Ratregion
5089985AU04948124149188086691881106Ratregion
5087616PMC57740P124548591270885912952Ratregion
5085004AI22973319048518792785189478Ratregion
5088345AU04851314749684124696841392Ratregion
5088623AU04867919948454001784540219Ratregion
5082595BE11981315649125868891258839Ratregion
5084510AI40975519748916856189168758Ratregion
5086262BM38483521048526846585268674Ratregion
5083127BF39081515049534151595341664Ratregion
5081639BE11774115748476015984760315Ratregion
5086843AA81923221448708895387089164Ratregion
5503105CRHR213748528872285289260Ratregion
5504224RH7556324848786670987866956Ratregion
5504969Tshr11249344762593447736Ratregion
5505820UniSTS:495551105448744094987442002Ratregion
5505760UniSTS:492639105048744094987441998Ratregion
5507175UniSTS:22501117848878874788788924Ratregion
5502718NEUROD643748591256185912997Ratregion
Position Markers

Flank 1: (D4Rat103)
Rat AssemblyChrPosition (strand)Source
Rnor_6.0484,475,257 - 84,475,486NCBI
Rnor_5.04149,135,946 - 149,136,175UniSTS
RGSC_v3.4482,700,691 - 82,700,921RGD
RGSC_v3.4482,700,692 - 82,700,921UniSTS
RGSC_v3.1482,985,313 - 82,985,543RGD
Celera478,304,079 - 78,304,308UniSTS
SHRSP x BN Map441.93UniSTS
SHRSP x BN Map441.93RGD
Peak: (D4Rat231)
Rat AssemblyChrPosition (strand)Source
Rnor_6.0489,777,552 - 89,777,772NCBI
Rnor_5.04154,593,964 - 154,594,184UniSTS
RGSC_v3.4488,462,327 - 88,462,549RGD
RGSC_v3.4488,462,328 - 88,462,549UniSTS
RGSC_v3.1488,706,752 - 88,706,974RGD
SHRSP x BN Map443.1UniSTS
SHRSP x BN Map443.1RGD
FHH x ACI Map454.64RGD
Flank 2: (D4Rat38)
Rat AssemblyChrPosition (strand)Source
Rnor_6.0497,479,009 - 97,479,149NCBI
Rnor_5.04162,263,905 - 162,264,045UniSTS
RGSC_v3.4496,313,186 - 96,313,326UniSTS
RGSC_v3.4496,313,180 - 96,313,512RGD
RGSC_v3.1496,557,667 - 96,557,807RGD
Celera490,553,749 - 90,553,889UniSTS
RH 3.4 Map4603.0UniSTS
RH 3.4 Map4603.0RGD
SHRSP x BN Map448.75RGD
SHRSP x BN Map448.75UniSTS
FHH x ACI Map459.12RGD


QTLs in Region (Rnor_6.0)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2303168Bp330Blood pressure QTL 3304.250.017arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)43043231145254791Rat
631261Tcas3Tongue tumor susceptibility QTL 36.88tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)4734240492484039Rat
2316958Gluco58Glucose level QTL 5810blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)47850904182171018Rat
10755501Bp390Blood pressure QTL 3902.5arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)423850384169318094Rat
12798520Anxrr55Anxiety related response QTL 554.450.01locomotor behavior trait (VT:0001392)number of rearing movements with lid-pushing in an experimental apparatus (CMO:0002715)429549895112807890Rat
8655961Kidm43Kidney mass QTL 4318kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)43427793299067150Rat
1358352Srcrt3Stress Responsive Cort QTL 32.29blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)436615599145611886Rat
1300139Hrtrt6Heart rate QTL 62.85heart pumping trait (VT:2000009)heart rate (CMO:0000002)437703272115372927Rat
6893678Bw108Body weight QTL 1082.60.006body mass (VT:0001259)body weight (CMO:0000012)44241577787415777Rat
1576305Emca6Estrogen-induced mammary cancer QTL 65.8mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)443414605155469929Rat
1354660Salc1Saline consumption QTL 111.26drinking behavior trait (VT:0001422)saline drink intake rate (CMO:0001627)443414792146942075Rat
1354612Foco1Food consumption QTL 18.87eating behavior trait (VT:0001431)food intake rate (CMO:0000427)443414792146942075Rat
1298082Stresp4Stress response QTL 4blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)446898276145611886Rat
2312567Glom19Glomerulus QTL 191.90.006kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)449906054145611886Rat
70200Alc18Alcohol consumption QTL 189.2drinking behavior trait (VT:0001422)ethanol intake volume to total fluid intake volume ratio (CMO:0001591)455324953148360954Rat
1641833Alc21Alcohol consumption QTL 218.60.0001drinking behavior trait (VT:0001422)ethanol drink intake rate (CMO:0001407)455375865125671711Rat
631546Bp86Blood pressure QTL 863.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)45579156492484312Rat
1578657Bss12Bone structure and strength QTL 128.9femur morphology trait (VT:0000559)femoral neck cross-sectional area (CMO:0001697)456092756101092756Rat
1578658Bss13Bone structure and strength QTL 138femur strength trait (VT:0010010)femoral neck polar moment of inertia (CMO:0001670)456092756101092756Rat
1558651Swd3Spike wave discharge measurement QTL 34.620.000024brain electrophysiology trait (VT:0010557)brain spike-and-wave discharge frequency (CMO:0001742)45710107792990863Rat
1358363Sradr3Stress Responsive Adrenal Weight QTL 36.19adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)458166424103166424Rat
738009Sach4Saccharine consumption QTL 44.90.000016consumption behavior trait (VT:0002069)saccharin intake volume to total fluid intake volume ratio (CMO:0001601)458640017154427984Rat
738016Alc16Alcohol consumption QTL 163.60.00015consumption behavior trait (VT:0002069)ethanol drink intake rate to body weight ratio (CMO:0001616)458640017154427984Rat
738031Alc14Alcohol consumption QTL 147.60.00003consumption behavior trait (VT:0002069)ethanol drink intake rate to body weight ratio (CMO:0001616)458640017154427984Rat
1549843Bw53Body weight QTL 530.0001body mass (VT:0001259)body weight gain (CMO:0000420)46043912799066957Rat
1549839Bw52Body weight QTL 520.0001body mass (VT:0001259)body weight gain (CMO:0000420)460439127113416139Rat
61418Pia5Pristane induced arthritis QTL 54.5joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)461038901127777403Rat
7394826Bw126Body weight QTL 1260.002body mass (VT:0001259)body weight gain (CMO:0000420)46170810388565113Rat
70192BpQTLcluster5Blood pressure QTL cluster 54.183arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)461708341113100992Rat
70192BpQTLcluster5Blood pressure QTL cluster 54.183arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)461708341113100992Rat
70192BpQTLcluster5Blood pressure QTL cluster 54.183arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)461708341113100992Rat
70192BpQTLcluster5Blood pressure QTL cluster 54.183arterial blood pressure trait (VT:2000000)percent change in mean arterial blood pressure (CMO:0002035)461708341113100992Rat
70192BpQTLcluster5Blood pressure QTL cluster 54.183arterial blood pressure trait (VT:2000000)percent change in systolic blood pressure (CMO:0000747)461708341113100992Rat
70192BpQTLcluster5Blood pressure QTL cluster 54.183arterial blood pressure trait (VT:2000000)absolute change in pulse pressure (CMO:0001882)461708341113100992Rat
70192BpQTLcluster5Blood pressure QTL cluster 54.183arterial blood pressure trait (VT:2000000)absolute change in mean arterial blood pressure (CMO:0000533)461708341113100992Rat
2300179Bmd50Bone mineral density QTL 505.90.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)461975371106975371Rat
1641919Alc22Alcohol consumption QTL 220.0005drinking behavior trait (VT:0001422)ethanol drink intake rate (CMO:0001407)462947687125671711Rat
631674Iddm14Insulin dependent diabetes mellitus QTL 14blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)463537179157286626Rat
6478684Anxrr30Anxiety related response QTL 300.00087defecation behavior trait (VT:0010462)defecation rate (CMO:0000998)463812687108812687Rat
6478743Anxrr40Anxiety related response QTL 400.83076defecation behavior trait (VT:0010462)defecation rate (CMO:0000998)463812687108812687Rat
6478772Anxrr49Anxiety related response QTL 490.15488defecation behavior trait (VT:0010462)defecation rate (CMO:0000998)463812687108812687Rat
631651Bp124Blood pressure QTL 1243arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)463938412108938412Rat
2312569Pur19Proteinuria QTL 193.40.001total urine protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)46598924397759057Rat
61330Eau1Experimental allergic uveoretinitis QTL 10.0003uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)470773471132455556Rat
634344Hcar7Hepatocarcinoma resistance QTL 77.8liver integrity trait (VT:0010547)liver tumorous lesion area to total liver area ratio (CMO:0001075)471476518116476518Rat
634344Hcar7Hepatocarcinoma resistance QTL 77.8liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)471476518116476518Rat
631646Stl4Serum triglyceride level QTL 46.50.0001blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)473786419132455556Rat
724522Bp146Blood pressure QTL 1462.20.0021arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)475258970120258970Rat
2302051Pia28Pristane induced arthritis QTL 285.30.001blood autoantibody amount (VT:0003725)serum immunoglobulin G-type rheumatoid factor level relative to an arbitrary reference serum (CMO:0002112)475258970120258970Rat
738015Pia9Pristane induced arthritis QTL 94.50.048joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)476567036121567036Rat
70167Bw22Body weight QTL 223.1body mass (VT:0001259)body weight (CMO:0000012)477307388116916073Rat
1357342Bw40Body weight QTL 400.001body mass (VT:0001259)body weight (CMO:0000012)477307388116916073Rat
631662Hcar2Hepatocarcinoma resistance QTL 23.10.0003liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)479555067124555067Rat
631556Bp135Blood pressure QTL 1350.017arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)479557856116916073Rat
61364Iddm2Insulin dependent diabetes mellitus QTL 2blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)47956245198542106Rat
2306899Bp338Blood pressure QTL 3380.071arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)481874073119546974Rat
70177Xhs1X-ray hypersensitivity QTL 125.1intestine integrity trait (VT:0010554)post-insult time to onset of moribundity (CMO:0001896)481959983152055009Rat
2306794Ean2Experimental allergic neuritis QTL 26.4nervous system integrity trait (VT:0010566)IFNG-secreting splenocyte count (CMO:0002122)48447525797479149Rat
1576316Ept5Estrogen-induced pituitary tumorigenesis QTL 53.8pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)484475257178931073Rat
634334Xhs3X-ray hypersensitivity QTL 310intestine integrity trait (VT:0010554)post-insult time to onset of moribundity (CMO:0001896)485794049129615056Rat
1582232Gluco25Glucose level QTL 253.60.0023blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)486312589146942261Rat
12798523Anxrr56Anxiety related response QTL 562.830.05locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)486312589147702403Rat
1358202Gluco11Glucose level QTL 112.40.02adipocyte glucose uptake trait (VT:0004185)absolute change in adipocyte glucose uptake (CMO:0000873)486438317168047091Rat
61476Aia3Adjuvant induced arthritis QTL 33.9joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)486532519131532519Rat
1578662Bss15Bone structure and strength QTL 1519.6femur width (VT:1000666)femoral neck width (CMO:0001695)487136446132136446Rat
1578670Bss14Bone structure and strength QTL 1416.4femur morphology trait (VT:0000559)bone trabecular cross-sectional area (CMO:0002311)487136446132136446Rat
2317587Eae26Experimental allergic encephalomyelitis QTL 26nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis severity score (CMO:0001419)48977755299067150Rat
631689Scl4Serum cholesterol level QTL 41.90.008blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)494414208139414208Rat
634335Anxrr16Anxiety related response QTL 167.22locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)494893247168046938Rat


Additional Information

RGD Curation Notes
Note Type Note Reference
qtl_cross_type intercross  
qtl_disease animals treated with agonist NADPH oxidase complex for Ncf1 gene showed dramatic reduction in disease score 2306769
qtl_general measurement method: rats were anesthetized by ether inhalation then bPNM (bovine peripheral nerve myelin) dissolved in PBS was injected at the base of the tail then scored: 0, normal; 1, less active; 2, limp tail; 3, absent righting; 4, gait ataxia; 5, mild paresis; 6, moderate paresis; 7, severe paraparesis; 8, tetraparesis; 9, moribund; 10, death; body weight was taken every second day 2306769
qtl_general number of animals used: 215 males and 235 females; 8-14 weeks old 2306769
qtl_general region responsible for strongly regulating IFN-gamma secretion by T cell activity 2306769
qtl_general inducing agent: bPNM (bovine peripheral nerve myelin) 2306769
 



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.