Imported Disease Annotations - CTDObject Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Plcl2 | Rat | schizophrenia | | ISO | PLCL2 (Homo sapiens) | 11554173 | CTD Direct Evidence: marker/mechanism | CTD | PMID:21822266 | |
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Imported Disease Annotations - CTDObject Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Plcl2 | Rat | schizophrenia | | ISO | PLCL2 (Homo sapiens) | 11554173 | CTD Direct Evidence: marker/mechanism | CTD | PMID:21822266 | |
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# | Reference Title | Reference Citation |
1. | Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. | Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27. |
2. | Rat ISS GO annotations from MGI mouse gene data--August 2006 | MGD data from the GO Consortium |
3. | Phospholipase C-related Catalytically Inactive Protein Is a New Modulator of Thermogenesis Promoted by beta-Adrenergic Receptors in Brown Adipocytes. | Oue K, etal., J Biol Chem. 2016 Feb 19;291(8):4185-96. doi: 10.1074/jbc.M115.705723. Epub 2015 Dec 25. |
4. | GOA pipeline | RGD automated data pipeline |
5. | ClinVar Automated Import and Annotation Pipeline | RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations |
6. | Data Import for Chemical-Gene Interactions | RGD automated import pipeline for gene-chemical interactions |
Plcl2 (Rattus norvegicus - Norway rat) |
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PLCL2 (Homo sapiens - human) |
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Plcl2 (Mus musculus - house mouse) |
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Plcl2 (Chinchilla lanigera - long-tailed chinchilla) |
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PLCL2 (Pan paniscus - bonobo/pygmy chimpanzee) |
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PLCL2 (Canis lupus familiaris - dog) |
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Plcl2 (Ictidomys tridecemlineatus - thirteen-lined ground squirrel) |
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PLCL2 (Sus scrofa - pig) |
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PLCL2 (Chlorocebus sabaeus - green monkey) |
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Plcl2 (Heterocephalus glaber - naked mole-rat) |
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Variants in Plcl2
591 total Variants |
The detailed report is available here: | Full Report | CSV | TAB | Printer | ||||
miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/). For more information about miRGate, see PMID:25858286 or access the full paper here. |
The following QTLs overlap with this region. | Full Report | CSV | TAB | Printer | Gviewer |
D9Rat162 |
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RH131115 |
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UniSTS:237662 |
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alimentary part of gastrointestinal system
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appendage
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circulatory system
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ectoderm
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endocrine system
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endoderm
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exocrine system
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hemolymphoid system
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hepatobiliary system
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integumental system
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mesenchyme
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mesoderm
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nervous system
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renal system
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reproductive system
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respiratory system
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9 | 11 | 49 | 113 | 91 | 90 | 59 | 25 | 59 | 6 | 218 | 97 | 93 | 45 | 60 | 31 |
RefSeq Transcripts | NM_001106880 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
XM_039083164 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_039083165 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XR_010054576 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XR_010054577 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
GenBank Nucleotide | CH474081 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
FQ226207 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
FQ233007 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
JAXUCZ010000009 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
Ensembl Acc Id: | ENSRNOT00000018146 ⟹ ENSRNOP00000018146 | ||||||||||||
Type: | CODING | ||||||||||||
Position: |
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Ensembl Acc Id: | ENSRNOT00000106190 ⟹ ENSRNOP00000084833 | ||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | NM_001106880 ⟹ NP_001100350 | ||||||||||||||||||||||||||||||||
RefSeq Status: | PROVISIONAL | ||||||||||||||||||||||||||||||||
Type: | CODING | ||||||||||||||||||||||||||||||||
Position: |
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Sequence: |
RefSeq Acc Id: | XM_039083164 ⟹ XP_038939092 | ||||||||||||
Type: | CODING | ||||||||||||
Position: |
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RefSeq Acc Id: | XM_039083165 ⟹ XP_038939093 | ||||||||||||
Type: | CODING | ||||||||||||
Position: |
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RefSeq Acc Id: | XR_010054576 | ||||||||
Type: | NON-CODING | ||||||||
Position: |
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RefSeq Acc Id: | XR_010054577 | ||||||||
Type: | NON-CODING | ||||||||
Position: |
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Protein RefSeqs | NP_001100350 | (Get FASTA) | NCBI Sequence Viewer |
XP_038939092 | (Get FASTA) | NCBI Sequence Viewer | |
XP_038939093 | (Get FASTA) | NCBI Sequence Viewer | |
GenBank Protein | EDL83023 | (Get FASTA) | NCBI Sequence Viewer |
Ensembl Protein | ENSRNOP00000018146.7 | ||
ENSRNOP00000084833.1 |
RefSeq Acc Id: | NP_001100350 ⟸ NM_001106880 |
- UniProtKB: | A6KPP0 (UniProtKB/TrEMBL), A0A8I5ZYT1 (UniProtKB/TrEMBL) |
- Sequence: |
Ensembl Acc Id: | ENSRNOP00000018146 ⟸ ENSRNOT00000018146 |
RefSeq Acc Id: | XP_038939093 ⟸ XM_039083165 |
- Peptide Label: | isoform X1 |
- UniProtKB: | F1M324 (UniProtKB/TrEMBL), A0A8I5ZYT1 (UniProtKB/TrEMBL) |
RefSeq Acc Id: | XP_038939092 ⟸ XM_039083164 |
- Peptide Label: | isoform X1 |
- UniProtKB: | F1M324 (UniProtKB/TrEMBL), A0A8I5ZYT1 (UniProtKB/TrEMBL) |
Ensembl Acc Id: | ENSRNOP00000084833 ⟸ ENSRNOT00000106190 |
Name | Modeler | Protein Id | AA Range | Protein Structure |
AF-F1M324-F1-model_v2 | AlphaFold | F1M324 | 1-1001 | view protein structure |
eQTL | View at Phenogen | |
WGCNA | View at Phenogen | |
Tissue/Strain Expression | View at Phenogen |
Database | Acc Id | Source(s) |
AGR Gene | RGD:1305941 | AgrOrtholog |
BioCyc Gene | G2FUF-28433 | BioCyc |
Ensembl Genes | ENSRNOG00000013368 | Ensembl, UniProtKB/TrEMBL |
Ensembl Transcript | ENSRNOT00000018146.8 | UniProtKB/TrEMBL |
ENSRNOT00000106190.1 | UniProtKB/TrEMBL | |
Gene3D-CATH | 2.30.29.30 | UniProtKB/TrEMBL |
2.60.40.150 | UniProtKB/TrEMBL | |
3.20.20.190 | UniProtKB/TrEMBL | |
EF-hand | UniProtKB/TrEMBL | |
InterPro | C2_Ca-dep | UniProtKB/TrEMBL |
C2_domain_sf | UniProtKB/TrEMBL | |
EF-hand-like_dom | UniProtKB/TrEMBL | |
PH_type | UniProtKB/TrEMBL | |
Phospholipase_C_EF-hand-like | UniProtKB/TrEMBL | |
Phospholipase_C_Pinositol-sp_Y | UniProtKB/TrEMBL | |
Pinositol_Phospholipase-C | UniProtKB/TrEMBL | |
PLC-like_Pdiesterase_TIM-brl | UniProtKB/TrEMBL | |
PLCL1/PLCL2 | UniProtKB/TrEMBL | |
Pleckstrin_homology | UniProtKB/TrEMBL | |
PLipase_C_PInositol-sp_X_dom | UniProtKB/TrEMBL | |
KEGG Report | rno:301173 | UniProtKB/TrEMBL |
NCBI Gene | 301173 | ENTREZGENE |
PANTHER | PTHR10336 | UniProtKB/TrEMBL |
PTHR10336:SF84 | UniProtKB/TrEMBL | |
Pfam | efhand_like | UniProtKB/TrEMBL |
PF00168 | UniProtKB/TrEMBL | |
PH_12 | UniProtKB/TrEMBL | |
PI-PLC-X | UniProtKB/TrEMBL | |
PI-PLC-Y | UniProtKB/TrEMBL | |
PhenoGen | Plcl2 | PhenoGen |
PRINTS | PHPHLIPASEC | UniProtKB/TrEMBL |
PROSITE | PH_DOMAIN | UniProtKB/TrEMBL |
PIPLC_X_DOMAIN | UniProtKB/TrEMBL | |
PIPLC_Y_DOMAIN | UniProtKB/TrEMBL | |
PS50004 | UniProtKB/TrEMBL | |
RatGTEx | ENSRNOG00000013368 | RatGTEx |
SMART | PLCXc | UniProtKB/TrEMBL |
PLCYc | UniProtKB/TrEMBL | |
SM00233 | UniProtKB/TrEMBL | |
SM00239 | UniProtKB/TrEMBL | |
Superfamily-SCOP | PH domain-like | UniProtKB/TrEMBL |
PLC-like_Pdiesterase_TIM-brl | UniProtKB/TrEMBL | |
SSF47473 | UniProtKB/TrEMBL | |
SSF49562 | UniProtKB/TrEMBL | |
UniProt | A0A8I5ZYT1 | ENTREZGENE, UniProtKB/TrEMBL |
A6KPP0 | ENTREZGENE, UniProtKB/TrEMBL | |
F1M324 | ENTREZGENE, UniProtKB/TrEMBL |
Date | Current Symbol | Current Name | Previous Symbol | Previous Name | Description | Reference | Status |
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2015-07-29 | Plcl2 | phospholipase C-like 2 | LOC680128 | similar to phospholipase C-like 2 | Data merged from RGD:1595495 | 737654 | PROVISIONAL |
2008-04-30 | Plcl2 | phospholipase C-like 2 | Plcl2_predicted | phospholipase C-like 2 (predicted) | 'predicted' is removed | 2292626 | APPROVED |
2006-11-20 | LOC680128 | similar to phospholipase C-like 2 | Symbol and Name status set to provisional | 70820 | PROVISIONAL | ||
2005-01-12 | Plcl2_predicted | phospholipase C-like 2 (predicted) | Symbol and Name status set to approved | 70820 | APPROVED |