Plcl2 (phospholipase C like 2) - Rat Genome Database

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Gene: Plcl2 (phospholipase C like 2) Chinchilla lanigera
Analyze
Symbol: Plcl2
Name: phospholipase C like 2
RGD ID: 9022593
Description: ENCODES a protein that exhibits GABA receptor binding (ortholog); INVOLVED IN B cell proliferation involved in immune response (ortholog); B-1a B cell differentiation (ortholog); gamma-aminobutyric acid signaling pathway (ortholog); ASSOCIATED WITH 3p deletion syndrome (ortholog); genetic disease (ortholog); schizophrenia (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: inactive phospholipase C-like protein 2; phospholipase C-like 2
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554309,157,074 - 9,348,563 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554309,157,074 - 9,347,366 (+)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Plcl2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554309,157,074 - 9,348,563 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554309,157,074 - 9,347,366 (+)NCBIChiLan1.0ChiLan1.0
PLCL2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38316,884,955 - 17,090,606 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl316,802,651 - 17,090,604 (+)EnsemblGRCh38hg38GRCh38
GRCh37316,926,448 - 17,132,098 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36316,949,586 - 17,107,089 (+)NCBINCBI36Build 36hg18NCBI36
Build 34316,949,585 - 17,107,089NCBI
Celera316,865,522 - 17,071,160 (+)NCBICelera
Cytogenetic Map3p24.3NCBI
HuRef316,860,717 - 17,066,984 (+)NCBIHuRef
CHM1_1316,877,832 - 17,083,991 (+)NCBICHM1_1
T2T-CHM13v2.0316,803,899 - 17,092,796 (+)NCBIT2T-CHM13v2.0
Plcl2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391750,815,893 - 50,995,522 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1750,816,431 - 50,995,512 (+)EnsemblGRCm39 Ensembl
GRCm381750,508,865 - 50,688,494 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1750,509,403 - 50,688,484 (+)EnsemblGRCm38mm10GRCm38
MGSCv371750,648,872 - 50,827,819 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361749,974,984 - 50,154,037 (+)NCBIMGSCv36mm8
Celera1753,955,768 - 54,144,820 (+)NCBICelera
Cytogenetic Map17CNCBI
cM Map1725.86NCBI
Plcl2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr893,529,117 - 3,713,712 (+)NCBIGRCr8
mRatBN7.293,292,564 - 3,477,009 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl93,292,695 - 3,477,009 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx94,459,203 - 4,644,048 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.099,631,258 - 9,816,096 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.098,764,438 - 8,949,289 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.091,782,536 - 1,984,654 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl91,782,536 - 1,984,654 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.091,813,654 - 1,937,548 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.091,740,384 - 1,773,917 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.494,687,320 - 4,873,780 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.194,687,896 - 4,877,255 (-)NCBI
Celera9198,050 - 381,326 (+)NCBICelera
Cytogenetic Map9q11NCBI
PLCL2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2216,795,633 - 17,074,904 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1316,800,391 - 17,079,668 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0316,736,430 - 17,015,531 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1317,154,506 - 17,351,287 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl317,154,500 - 17,351,287 (+)Ensemblpanpan1.1panPan2
PLCL2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12325,814,392 - 25,999,666 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2325,814,862 - 25,999,749 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2325,789,455 - 25,974,932 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02326,315,064 - 26,500,436 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2326,315,091 - 26,556,082 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12326,016,655 - 26,201,771 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02326,077,652 - 26,263,001 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02326,326,490 - 26,512,317 (-)NCBIUU_Cfam_GSD_1.0
Plcl2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118176,490,039 - 176,663,140 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364739,627,811 - 9,802,132 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364739,628,612 - 9,801,713 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PLCL2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl133,992,835 - 4,201,569 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1133,992,230 - 4,201,574 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2134,457,260 - 4,510,455 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PLCL2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11561,745,338 - 61,940,176 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1561,745,163 - 61,942,655 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604134,728,205 - 34,928,173 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Plcl2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248212,131,851 - 2,315,934 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248212,132,075 - 2,316,624 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSCLAT00000009851   ⟹   ENSCLAP00000009722
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049554309,157,074 - 9,348,563 (+)Ensembl
RefSeq Acc Id: XM_005387455   ⟹   XP_005387512
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554309,157,074 - 9,347,366 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005387512 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000009722
  ENSCLAP00000009722.1
Reference Protein Sequences
RefSeq Acc Id: XP_005387512   ⟸   XM_005387455
- UniProtKB: A0A8C2V464 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCLAP00000009722   ⟸   ENSCLAT00000009851
Protein Domains
C2   PH   PI-PLC Y-box


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000006737 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000009851 ENTREZGENE
  ENSCLAT00000009851.1 UniProtKB/TrEMBL
Gene3D-CATH 2.30.29.30 UniProtKB/TrEMBL
  2.60.40.150 UniProtKB/TrEMBL
  3.20.20.190 UniProtKB/TrEMBL
  EF-hand UniProtKB/TrEMBL
InterPro C2_dom UniProtKB/TrEMBL
  C2_domain_sf UniProtKB/TrEMBL
  EF-hand-dom_pair UniProtKB/TrEMBL
  PH-like_dom_sf UniProtKB/TrEMBL
  PH_domain UniProtKB/TrEMBL
  PI-PLC_fam UniProtKB/TrEMBL
  PLC-like_Pdiesterase_TIM-brl UniProtKB/TrEMBL
  PLC_EF-hand-like UniProtKB/TrEMBL
  PLCL2 UniProtKB/TrEMBL
  PLipase_C_PInositol-sp_X_dom UniProtKB/TrEMBL
  PLipase_C_Pinositol-sp_Y UniProtKB/TrEMBL
NCBI Gene Plcl2 ENTREZGENE
PANTHER PTHR10336 UniProtKB/TrEMBL
  PTHR10336:SF84 UniProtKB/TrEMBL
Pfam EF-hand_like UniProtKB/TrEMBL
  PF00168 UniProtKB/TrEMBL
  PH_12 UniProtKB/TrEMBL
  PI-PLC-X UniProtKB/TrEMBL
  PI-PLC-Y UniProtKB/TrEMBL
PRINTS PHPHLIPASEC UniProtKB/TrEMBL
PROSITE PH_DOMAIN UniProtKB/TrEMBL
  PIPLC_X_DOMAIN UniProtKB/TrEMBL
  PIPLC_Y_DOMAIN UniProtKB/TrEMBL
  PS50004 UniProtKB/TrEMBL
SMART PLCXc UniProtKB/TrEMBL
  PLCYc UniProtKB/TrEMBL
  SM00233 UniProtKB/TrEMBL
  SM00239 UniProtKB/TrEMBL
Superfamily-SCOP PH domain-like UniProtKB/TrEMBL
  SSF47473 UniProtKB/TrEMBL
  SSF49562 UniProtKB/TrEMBL
  SSF51695 UniProtKB/TrEMBL
UniProt A0A8C2V464 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-08-16 Plcl2  phospholipase C like 2    phospholipase C-like 2  Symbol and/or name change 5135510 APPROVED