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Gene: Gnl1 (G protein nucleolar 1) Rattus norvegicus

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Symbol:

Gnl1

Name:

G protein nucleolar 1

RGD ID:

1303051

Description:

Predicted to enable GTPase activity. Predicted to be involved in DNA damage response. Orthologous to human GNL1 (G protein nucleolar 1 (putative)); INTERACTS WITH 2,4-dinitrotoluene; 2,6-dinitrotoluene; allethrin.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

guanine nucleotide binding protein-like 1; guanine nucleotide-binding protein-like 1

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	GNL1 (G protein nucleolar 1 (putative))	HGNC	Ensembl, HomoloGene, Inparanoid, NCBI, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Gnl1 (guanine nucleotide binding protein-like 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Gnl1 (G protein nucleolar 1 (putative))	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	GNL1 (G protein nucleolar 1 (putative))	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	GNL1 (G protein nucleolar 1 (putative))	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Gnl1 (G protein nucleolar 1 (putative))	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	GNL1 (G protein nucleolar 1 (putative))	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	GNL1 (G protein nucleolar 1 (putative))	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Gnl1 (G protein nucleolar 1 (putative))	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	GNL1 (G protein nucleolar 1 (putative))	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Gnl1 (guanine nucleotide binding protein-like 1)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	gnl1 (guanine nucleotide binding protein-like 1)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	Ns4	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	gnl1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB)

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	20	2,787,939 - 2,796,924 (-)	NCBI		GRCr8
mRatBN7.2	20	2,783,130 - 2,792,115 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	20	2,778,985 - 2,792,115 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	20	2,834,591 - 2,843,598 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	20	2,839,560 - 2,848,567 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	20	2,866,094 - 2,875,102 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	20	3,290,543 - 3,299,494 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	20	3,287,506 - 3,299,580 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	20	5,388,709 - 5,397,660 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	20	2,931,792 - 2,940,778 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	20	2,925,982 - 2,941,148 (-)	NCBI
Celera	20	209,123 - 218,113 (-)	NCBI		Celera
Cytogenetic Map	20	p12	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

megacolon (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dimethylhydrazine (ISO)

2,4-dinitrotoluene (EXP)

2,6-dinitrotoluene (EXP)

3,3',5,5'-tetrabromobisphenol A (ISO)

3,4-methylenedioxymethamphetamine (ISO)

all-trans-retinoic acid (ISO)

allethrin (EXP)

amiodarone (EXP)

antirheumatic drug (ISO)

aristolochic acid A (ISO)

arsane (ISO)

arsenic atom (ISO)

benzo[a]pyrene (ISO)

benzo[a]pyrene diol epoxide I (ISO)

bisphenol A (EXP,ISO)

bisphenol F (ISO)

caffeine (ISO)

carbon nanotube (ISO)

chromium(6+) (ISO)

clofibrate (ISO)

coumarin (ISO)

cyhalothrin (EXP)

cypermethrin (EXP)

decabromodiphenyl ether (ISO)

dextran sulfate (ISO)

Dibutyl phosphate (ISO)

doxorubicin (ISO)

elemental selenium (ISO)

ethanol (ISO)

fenvalerate (EXP)

folic acid (ISO)

FR900359 (ISO)

fulvestrant (ISO)

ozone (ISO)

paracetamol (EXP,ISO)

pyrethrins (EXP)

quercetin (ISO)

SB 431542 (ISO)

selenium atom (ISO)

sodium arsenite (ISO)

sunitinib (ISO)

testosterone (ISO)

titanium dioxide (ISO)

toluene (EXP)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

biological_process (ND)

DNA damage response (IEA,ISO)

Molecular Function

GTP binding (IEA)

GTPase activity (IBA,IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	GOA pipeline	RGD automated data pipeline
3.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
5.	Comprehensive gene review and curation	RGD comprehensive gene curation
6.	Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.	Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.

Additional References at PubMed

PMID:17525332	PMID:21630459

Genomics

Comparative Map Data

Gnl1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	20	2,787,939 - 2,796,924 (-)	NCBI		GRCr8
mRatBN7.2	20	2,783,130 - 2,792,115 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	20	2,778,985 - 2,792,115 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	20	2,834,591 - 2,843,598 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	20	2,839,560 - 2,848,567 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	20	2,866,094 - 2,875,102 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	20	3,290,543 - 3,299,494 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	20	3,287,506 - 3,299,580 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	20	5,388,709 - 5,397,660 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	20	2,931,792 - 2,940,778 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	20	2,925,982 - 2,941,148 (-)	NCBI
Celera	20	209,123 - 218,113 (-)	NCBI		Celera
Cytogenetic Map	20	p12	NCBI

GNL1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	6	30,541,381 - 30,556,489 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	6	30,541,381 - 30,556,489 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	6	30,509,158 - 30,524,266 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	6	30,621,673 - 30,632,987 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	6	30,621,672 - 30,632,987	NCBI
Celera	6	32,107,271 - 32,123,489 (-)	NCBI		Celera
Cytogenetic Map	6	p21.33	NCBI
HuRef	6	30,309,219 - 30,325,437 (-)	NCBI		HuRef
CHM1_1	6	30,511,264 - 30,527,480 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	6	30,405,556 - 30,420,665 (-)	NCBI		T2T-CHM13v2.0

Gnl1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	17	36,290,847 - 36,300,354 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	17	36,290,743 - 36,300,354 (+)	Ensembl		GRCm39 Ensembl
GRCm38	17	35,979,955 - 35,989,462 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	17	35,979,851 - 35,989,462 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	17	36,116,900 - 36,126,407 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	17	35,588,731 - 35,596,919 (+)	NCBI		MGSCv36	mm8
Celera	17	39,493,555 - 39,503,904 (+)	NCBI		Celera
Cytogenetic Map	17	B1	NCBI
cM Map	17	18.82	NCBI

Gnl1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955583	568,927 - 578,676 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955583	570,573 - 578,423 (-)	NCBI	ChiLan1.0	ChiLan1.0

GNL1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	5	45,104,367 - 45,115,130 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	6	41,062,850 - 41,077,729 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	6	30,284,204 - 30,300,493 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	6	31,154,749 - 31,171,447 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	6	31,154,749 - 31,171,449 (-)	Ensembl	panpan1.1		panPan2

GNL1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	12	375,485 - 383,713 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	12	375,593 - 383,347 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	12	513,168 - 521,708 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	12	519,433 - 527,975 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	12	519,437 - 527,959 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	12	376,177 - 384,708 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	12	445,507 - 454,045 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	12	515,297 - 523,817 (-)	NCBI		UU_Cfam_GSD_1.0

Gnl1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404946	33,859,235 - 33,873,928 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936837	224,487 - 239,127 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936837	228,680 - 239,253 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

GNL1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	7	23,098,185 - 23,112,950 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	7	23,102,877 - 23,112,414 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	7	26,772,421 - 26,782,003 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

GNL1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	17	41,898,562 - 41,911,042 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	17	41,900,530 - 41,910,934 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666044	30,210,390 - 30,221,891 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Gnl1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624754	25,133,563 - 25,141,725 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624754	25,133,532 - 25,141,725 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Gnl1
57 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	115
Count of miRNA genes:	104
Interacting mature miRNAs:	108
Transcripts:	ENSRNOT00000050373
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
61472	Aia1	Adjuvant induced arthritis QTL 1	18	0.001	joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	20	2646395	4597031	Rat
2306850	Pia40	Pristane induced arthritis QTL 40		0.0001	joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	20	1527959	5304575	Rat
1641915	Colcr9	Colorectal carcinoma resistance QTL 9	2.97	0.0024	intestine integrity trait (VT:0010554)	benign colorectal tumor number (CMO:0001795)	20	1530655	46530655	Rat
7387283	Uae44	Urinary albumin excretion QTL 44		0.1712	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	20	1	26123605	Rat
7411668	Foco32	Food consumption QTL 32	8	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	20	1	36600972	Rat
2305926	Iddm37	Insulin dependent diabetes mellitus QTL 37	6		blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	20	1527842	46527842	Rat
1354642	Despr15	Despair related QTL 15		0.0027	locomotor behavior trait (VT:0001392)	amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)	20	1	24159021	Rat
1600382	Edcs3	Endometrial carcinoma susceptibility QTL3	3.5	0.003	uterus morphology trait (VT:0001120)	percentage of study population developing endometrioid carcinoma during a period of time (CMO:0001759)	20	1	25159026	Rat
61448	Ciaa1	CIA Autoantibody QTL 1	30	0.001	blood autoantibody amount (VT:0003725)	calculated serum anti-rat type 2 collagen autoantibody titer (CMO:0001281)	20	2646395	4597031	Rat
8694189	Bw153	Body weight QTL 153	3.13	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	20	1	29191651	Rat
724519	Bp144	Blood pressure QTL 144		0.001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	20	1	3624629	Rat
9590109	Sffal8	Serum free fatty acids level QTL 8	5.32	0.01	blood free fatty acid amount (VT:0001553)	plasma free fatty acids level (CMO:0000546)	20	1	29191651	Rat
9590275	Scort15	Serum corticosterone level QTL 15	3.48	0.001	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	20	1	29191651	Rat
9589155	Insul32	Insulin level QTL 32	6.38	0.001	blood insulin amount (VT:0001560)	plasma insulin level (CMO:0000342)	20	1	29191651	Rat
7411650	Foco23	Food consumption QTL 23	20.7	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	20	1	29191651	Rat
2317851	Alcrsp22	Alcohol response QTL 22	3.2	0.05	response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	20	1	27339237	Rat
1598816	Memor12	Memory QTL 12	2.4		exploratory behavior trait (VT:0010471)	average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)	20	2606836	47606836	Rat
1641893	Alcrsp7	Alcohol response QTL 7			response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	20	1	27339237	Rat
6893685	Bw111	Body weight QTL 111	2.7	0.004	body mass (VT:0001259)	body weight (CMO:0000012)	20	1	32578807	Rat
9590252	Scort12	Serum corticosterone level QTL 12	20.46	0.001	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	20	1	36600972	Rat

Markers in Region

RH132743

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	20	2,783,278 - 2,783,761 (+)	MAPPER	mRatBN7.2
Rnor_6.0	20	3,290,692 - 3,291,174	NCBI	Rnor6.0
Rnor_5.0	20	5,388,858 - 5,389,340	UniSTS	Rnor5.0
RGSC_v3.4	20	2,931,941 - 2,932,423	UniSTS	RGSC3.4
Celera	20	209,272 - 209,754	UniSTS
Cytogenetic Map	20	p12	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	renal system	reproductive system	respiratory system
9	11	49	113	91	90	59	25	59	6	218	97	93	45	60	31

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_212500	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	BC083888	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC129081	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BX883048	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH474118	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000020	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000050373 ⟹ ENSRNOP00000045697

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	20	2,783,131 - 2,792,115 (-)	Ensembl
Rnor_6.0 Ensembl	20	3,290,543 - 3,299,580 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000078699

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0 Ensembl	20	3,295,631 - 3,296,984 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000083617 ⟹ ENSRNOP00000072902

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0 Ensembl	20	3,290,645 - 3,298,835 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000090999 ⟹ ENSRNOP00000073902

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	20	2,778,985 - 2,792,057 (-)	Ensembl
Rnor_6.0 Ensembl	20	3,287,506 - 3,299,420 (-)	Ensembl

RefSeq Acc Id:

NM_212500 ⟹ NP_997665

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	20	2,787,939 - 2,796,924 (-)	NCBI
mRatBN7.2	20	2,783,130 - 2,792,115 (-)	NCBI
Rnor_6.0	20	3,290,543 - 3,299,494 (-)	NCBI
Rnor_5.0	20	5,388,709 - 5,397,660 (-)	NCBI
RGSC_v3.4	20	2,931,792 - 2,940,778 (-)	RGD
Celera	20	209,123 - 218,113 (-)	RGD

Sequence:

show sequence

GCCGCCCGCCGCTGACGTCACCGCGGCCCCGCCTCCCCAGGGCCCCGGGCCGCGGGCGGGGGCT
GCCCGGGGGAGTCAGTTGCGGCGGCGGGGAGCTCGGCGGAGGGCGGACCGGGGCTCCGGGGCCA
TGCCGAGGAAGAAGCCCTTCAGCGTGAAGCAGAAGAAGAAGCAGCTGCAGGACAAGCGGGAGCG
GAAGCGAGGGCTCCAAGATGGGCTTCGCTCCAGTTCCAACAGCCGCAGCGGGAGCCGGGAGCGG
CGGGAGGAGCAGACCGACACGTCGGATGGGGAATCCGTGACCCATCACATCCGCAGGCTCAACC
AGCAACCTTCTCAGGGCCTGGGGCCCAGAGGCTACGACCCCAACCGATACCGGCTGCATTTTGA
ACGGGACAGCCGGGAAGAGGTGGAGAGGAGAAAGAGAGCAGCCAGAGAGCAGGTGTTGCAGCCA
GTCAGTGCTGAAATGCTGGAGTTGGATATCCAGGAAGTATATCAGCCTGGCTCAGTTCTGGACT
TCCCCCGGCGACCTCCTTGGAGTTATGAGATGTCCAAGGAGCAACTAATGAGCCAAGAGGAGCG
GAGCTTCCAGGAATACCTTGGGAAGATACATGGGGCATACACTTCGGAGAAACTCAGCTACTTT
GAGCACAATTTGGAGACATGGAGGCAGCTGTGGCGTGTGTTAGAGATGTCTGACATCGTCTTGC
TCATTACGGACATCCGACATCCGGTTGTGAACTTCCCACCAGCACTTTACGAGTATGTAACCGG
AGAACTTGGGCTGGCTCTGGTGCTGGTCTTGAATAAGGTGGACCTGGCCCCGCCAGCTCTTGTG
GTGGCCTGGAAGCATTATTTCCACCAGCACTACCCCCAGCTCCACATTGTCCTGTTCACCTCTT
TCCCTCGGGACACTCGGACTCCACAGGAGCCTGGTAGTGTCTTGAAGAAGAGTCGGAGACGGGG
CAGAGGATGGACTCGGGCGCTGGGGCCAGAGCAGTTGCTGAGAGCCTGTGAAGCCATCACTGTG
GGGAAAGTGGACTTGAGCAGTTGGCGAGAGAAGATTGCTAGGGACGTGGCCGGGGCCTCGTGGG
GTAATGTCTCTGGTGAGGAAGAGGAGGAGGAGGACGGGCCAGCAGTACTGGTAGAGCAGCAGAC
TGACTCAGCGATGGAGCCCACGGGCCCCTCCAGGGAGCGCTACAAGGATGGGGTGGTGACCATC
GGCTGTGTAGGTTTCCCCAATGTGGGGAAGTCCTCGCTGATCAACGGGCTGGTGGGGCGGAAGG
TGGTGAGTGTCTCCAGAACGCCAGGCCATACCCGGTACTTTCAGACTTACTTTCTCACCCCGTC
TGTGAAGCTCTGTGACTGTCCAGGCCTTATCTTCCCCTCTCTGCTGCCCAGACAGCTGCAGGTT
CTGGCTGGAATCTACCCCATTGCCCAGATCCAGGAGCCCTACACTTCCGTGGGCTACCTGGCCT
GCAGAATCCCGGTGCAGGCCCTGCTGCACCTGCGCCACCCAGAGGCAGAGGACCCTTCAGCCGA
GCATCCCTGGTGTGCCTGGGACGTCTGCGAAGCCTGGGCAGAGAAACGTGGCTATAAAACGGCC
AAGGCAGCTCGAAACGATGTGTACAGAGCAGCCAACAGCCTCCTTCGCCTGGCAGTGGATGGCC
GTCTCAGCCTGTGTTTCCACCCTCCTGGCTATAGCGAACAGAGAGGCACCTGGGAGTCTCACGC
AGAGACTGCAGAGCTGGTGCTGTCCCAGGGCAGGGTGGGGCCGGCAGGTGATGAAGAGGAGGAG
GAAGAGGAGGAGCTGAGCAGCTCCTGTGAGGAGGAAGGAGAGGAGGACCGAGATGCAGATGAAG
AGGGGGAAGGAGATGAAGACACCCCAACTTCAGATACTGGGTCCTGCCTAGCAGCCCGAAACCC
ATATGCCCTGCTAGGGGAGGGTGAGTGCTGAGCCTGCCGGGTTCCAAACGCCCTGGGGAGCTTT
GATTCTGGGCTGAGCGGGAGGTGTCTTCCCTGTGCCACCCTGATTGTGAATAAAGATTGTCTGC
TTTGTAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA

hide sequence

Protein Sequences


Protein RefSeqs	NP_997665	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH83888	(Get FASTA)	NCBI Sequence Viewer
	AAI29082	(Get FASTA)	NCBI Sequence Viewer
	CAE84041	(Get FASTA)	NCBI Sequence Viewer
	EDL86713	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000045697.3
	ENSRNOP00000073902.1
GenBank Protein	Q6MG06	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_997665 ⟸ NM_212500

- UniProtKB:

Q6MG06 (UniProtKB/Swiss-Prot), A6KT59 (UniProtKB/TrEMBL), A0A0G2K6Q5 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MPRKKPFSVKQKKKQLQDKRERKRGLQDGLRSSSNSRSGSRERREEQTDTSDGESVTHHIRRLN
QQPSQGLGPRGYDPNRYRLHFERDSREEVERRKRAAREQVLQPVSAEMLELDIQEVYQPGSVLD
FPRRPPWSYEMSKEQLMSQEERSFQEYLGKIHGAYTSEKLSYFEHNLETWRQLWRVLEMSDIVL
LITDIRHPVVNFPPALYEYVTGELGLALVLVLNKVDLAPPALVVAWKHYFHQHYPQLHIVLFTS
FPRDTRTPQEPGSVLKKSRRRGRGWTRALGPEQLLRACEAITVGKVDLSSWREKIARDVAGASW
GNVSGEEEEEEDGPAVLVEQQTDSAMEPTGPSRERYKDGVVTIGCVGFPNVGKSSLINGLVGRK
VVSVSRTPGHTRYFQTYFLTPSVKLCDCPGLIFPSLLPRQLQVLAGIYPIAQIQEPYTSVGYLA
CRIPVQALLHLRHPEAEDPSAEHPWCAWDVCEAWAEKRGYKTAKAARNDVYRAANSLLRLAVDG
RLSLCFHPPGYSEQRGTWESHAETAELVLSQGRVGPAGDEEEEEEEELSSSCEEEGEEDRDADE
EGEGDEDTPTSDTGSCLAARNPYALLGEGEC

hide sequence

Ensembl Acc Id:

ENSRNOP00000073902 ⟸ ENSRNOT00000090999

Ensembl Acc Id:

ENSRNOP00000072902 ⟸ ENSRNOT00000083617

Ensembl Acc Id:

ENSRNOP00000045697 ⟸ ENSRNOT00000050373

Protein Domains

CP-type G

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q6MG06-F1-model_v2	AlphaFold	Q6MG06	1-607	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13701295

Promoter ID:

EPDNEW_R11813

Type:

multiple initiation site

Name:

Gnl1_1

Description:

G protein nucleolar 1

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Alternative Promoters:

null; see alsoEPDNEW_R11814

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	20	3,299,417 - 3,299,477	EPDNEW

RGD ID:

13701290

Promoter ID:

EPDNEW_R11814

Type:

multiple initiation site

Name:

Gnl1_2

Description:

G protein nucleolar 1

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Alternative Promoters:

null; see alsoEPDNEW_R11813

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	20	3,299,566 - 3,299,626	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1303051	AgrOrtholog
BioCyc Gene	G2FUF-4794	BioCyc
Ensembl Genes	ENSRNOG00000000798	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000050373.5	UniProtKB/TrEMBL
	ENSRNOT00000090999.2	UniProtKB/TrEMBL
Gene3D-CATH	3.40.50.300	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE	IMAGE:7132380	IMAGE-MGC_LOAD
	IMAGE:7442774	IMAGE-MGC_LOAD
InterPro	G_CP_dom	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	GNL1-like	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	GTP_binding_domain	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	P-loop_NTPase	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	rno:309593	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGC_CLONE	MGC:156548	IMAGE-MGC_LOAD
	MGC:95211	IMAGE-MGC_LOAD
NCBI Gene	309593	ENTREZGENE
PANTHER	GUANINE NUCLEOTIDE-BINDING PROTEIN-LIKE 1	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	PTHR45709	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam	MMR_HSR1	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen	Gnl1	PhenoGen
PROSITE	G_CP	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000000798	RatGTEx
Superfamily-SCOP	SSF52540	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt	A0A0G2K6Q5	ENTREZGENE, UniProtKB/TrEMBL
	A0A8L2QM79_RAT	UniProtKB/TrEMBL
	A6KT59	ENTREZGENE, UniProtKB/TrEMBL
	GNL1_RAT	UniProtKB/Swiss-Prot
	Q5XI09_RAT	UniProtKB/TrEMBL
	Q6MG06	ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2016-03-15	Gnl1	G protein nucleolar 1	Gnl1	guanine nucleotide binding protein-like 1	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2005-02-14	Gnl1	guanine nucleotide binding protein-like 1			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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