Xirp2 (xin actin-binding repeat containing 2) - Rat Genome Database

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Gene: Xirp2 (xin actin-binding repeat containing 2) Rattus norvegicus
Analyze
Symbol: Xirp2
Name: xin actin-binding repeat containing 2
RGD ID: 1302980
Description: Predicted to enable actin filament binding activity and alpha-actinin binding activity. Predicted to be involved in actin filament organization and regulation of actin filament organization. Predicted to act upstream of or within cardiac muscle tissue morphogenesis; cell-cell junction organization; and ventricular septum development. Predicted to be located in Z disc. Predicted to colocalize with focal adhesion and stress fiber. Human ortholog(s) of this gene implicated in depressive disorder. Orthologous to human XIRP2 (xin actin binding repeat containing 2); INTERACTS WITH 2,3,7,8-Tetrachlorodibenzofuran; acrylamide; alpha-Zearalanol.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: beta-xin; cardiomyopathy associated 3; cardiomyopathy-associated protein 3; Cmya3; L-NAME induced actin cytoskeletal protein; L-NAME-induced actin cytoskeletal protein; LACS; xin actin-binding repeat-containing protein 2
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8372,534,175 - 72,621,056 (+)NCBIGRCr8
mRatBN7.2352,126,213 - 52,213,094 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl351,870,092 - 52,213,091 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx355,498,043 - 55,591,613 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0364,081,635 - 64,175,194 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0361,847,934 - 61,934,807 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0353,563,207 - 53,658,113 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl353,563,194 - 53,658,132 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0360,181,174 - 60,274,635 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4349,414,869 - 49,502,136 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1349,311,240 - 49,398,505 (+)NCBI
Celera351,697,264 - 51,784,744 (+)NCBICelera
Cytogenetic Map3q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
anchoring junction  (IEA)
cell-cell junction  (ISO)
focal adhesion  (IBA,IEA,ISO)
stress fiber  (IBA,IEA,ISO)
Z disc  (ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Mutation burden analysis of six common mental disorders in African Americans by whole genome sequencing. Liu Y, etal., Hum Mol Genet. 2022 Nov 10;31(22):3769-3776. doi: 10.1093/hmg/ddac129.
3. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
5. Information Derived from GenBank Report RGD, Sept. 2003
Additional References at PubMed
PMID:15454575   PMID:17046827   PMID:20360251   PMID:22871113   PMID:35352799  


Genomics

Comparative Map Data
Xirp2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8372,534,175 - 72,621,056 (+)NCBIGRCr8
mRatBN7.2352,126,213 - 52,213,094 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl351,870,092 - 52,213,091 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx355,498,043 - 55,591,613 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0364,081,635 - 64,175,194 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0361,847,934 - 61,934,807 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0353,563,207 - 53,658,113 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl353,563,194 - 53,658,132 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0360,181,174 - 60,274,635 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4349,414,869 - 49,502,136 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1349,311,240 - 49,398,505 (+)NCBI
Celera351,697,264 - 51,784,744 (+)NCBICelera
Cytogenetic Map3q21NCBI
XIRP2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382166,888,480 - 167,259,753 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2166,888,480 - 167,259,753 (+)EnsemblGRCh38hg38GRCh38
GRCh372167,744,990 - 168,116,263 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362167,468,221 - 167,824,509 (+)NCBINCBI36Build 36hg18NCBI36
Celera2161,368,680 - 161,725,410 (+)NCBICelera
Cytogenetic Map2q24.3NCBI
HuRef2159,625,428 - 159,996,667 (+)NCBIHuRef
CHM1_12167,750,858 - 168,122,133 (+)NCBICHM1_1
T2T-CHM13v2.02167,346,432 - 167,717,651 (+)NCBIT2T-CHM13v2.0
Xirp2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39267,276,343 - 67,356,964 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl267,004,178 - 67,356,959 (+)EnsemblGRCm39 Ensembl
GRCm38267,446,000 - 67,526,620 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl267,173,834 - 67,526,615 (+)EnsemblGRCm38mm10GRCm38
MGSCv37267,284,059 - 67,364,663 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36267,246,841 - 67,327,445 (+)NCBIMGSCv36mm8
Celera269,121,528 - 69,202,070 (+)NCBICelera
Cytogenetic Map2C1.3NCBI
cM Map239.31NCBI
Xirp2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554497,052,613 - 7,131,792 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554497,054,636 - 7,131,668 (-)NCBIChiLan1.0ChiLan1.0
XIRP2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21369,534,910 - 69,901,422 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12B69,549,886 - 69,916,398 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02B54,445,543 - 54,516,773 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12B171,919,285 - 171,990,122 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B171,642,482 - 171,989,732 (+)Ensemblpanpan1.1panPan2
XIRP2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13612,160,013 - 12,234,663 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3611,939,793 - 12,234,270 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3612,233,694 - 12,308,249 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03612,281,195 - 12,355,878 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3612,057,239 - 12,355,868 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13612,367,566 - 12,440,332 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03612,347,127 - 12,413,286 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03612,464,320 - 12,538,902 (+)NCBIUU_Cfam_GSD_1.0
Xirp2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303129,399,501 - 129,441,169 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493646912,176,498 - 12,190,641 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493646912,176,543 - 12,243,510 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
XIRP2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1573,422,267 - 73,741,134 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11573,665,876 - 73,741,046 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21582,522,547 - 82,597,615 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Pig Cytomap15q15-q22NCBI
XIRP2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11052,382,131 - 52,759,563 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1052,705,531 - 52,753,355 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666040146,764,839 - 146,818,771 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Xirp2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247874,912,862 - 5,002,551 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247874,912,941 - 4,998,889 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Xirp2
636 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:222
Count of miRNA genes:140
Interacting mature miRNAs:180
Transcripts:ENSRNOT00000048300
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300178Hrtrt4Heart rate QTL 43.74heart pumping trait (VT:2000009)heart rate (CMO:0000002)34382736490905114Rat
2302055Pia30Pristane induced arthritis QTL 303.50.001blood autoantibody amount (VT:0003725)serum immunoglobulin M-type rheumatoid factor level relative to an arbitrary reference serum (CMO:0002111)32793691972936919Rat
634317Bw117Body weight QTL 1173.58abdominal fat pad mass (VT:1000711)abdominal fat pad weight to body weight ratio (CMO:0000095)33945463753296578Rat
1331795Rf30Renal function QTL 303.708urine potassium amount (VT:0010539)urine potassium level (CMO:0000128)33945463789115240Rat
70216Cm14Cardiac mass QTL 142.1heart mass (VT:0007028)heart wet weight (CMO:0000069)331172320163586636Rat
1354589Bw31Body weight QTL 313.3body mass (VT:0001259)body weight (CMO:0000012)33370334778196190Rat
2303593Gluco46Glucose level QTL 463blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)32846857173468571Rat
1354590Despr11Despair related QTL 110.000031locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)32846857173468571Rat
2298542Neuinf11Neuroinflammation QTL 113.9nervous system integrity trait (VT:0010566)spinal cord complement component 1, q subcomponent, B chain mRNA level (CMO:0002126)31500542276927699Rat
2292591Esta4Estrogen-induced thymic atrophy QTL 4thymus mass (VT:0004954)thymus wet weight (CMO:0000855)347233211147415807Rat
1358362Srcrt2Stress Responsive Cort QTL 22.78blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)338192233133483320Rat
737818Hcar12Hepatocarcinoma resistance QTL 122.6liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)329463235118376539Rat
1331777Bw24Body weight QTL 243.503body mass (VT:0001259)body weight (CMO:0000012)33945463789115240Rat
631647Bp122Blood pressure QTL 1226.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)33068464275684642Rat
1300169Bp177Blood pressure QTL 1772.96arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)33370334761017857Rat
9590286Uminl1Urine mineral level QTL 13.50.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)32824968773249687Rat
724523Tsu1Thymus enlargement suppressive QTL 13.84thymus mass (VT:0004954)thymus weight to body weight ratio (CMO:0000612)350437504115638231Rat
1559282Emca5Estrogen-induced mammary cancer QTL 53.9mammary gland integrity trait (VT:0010552)percentage of study population developing mammary tumors during a period of time (CMO:0000948)343827364169034231Rat
2302276Bw82Body weight QTL 824.32body mass (VT:0001259)body weight (CMO:0000012)33945463762951183Rat
1581503Cm58Cardiac mass QTL 582.70.05heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)343827364121056321Rat
2292613Ept16Estrogen-induced pituitary tumorigenesis QTL 168.3pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)347233430110362260Rat
738019Anxrr10Anxiety related response QTL 103.9exploratory behavior trait (VT:0010471)number of entries into a discrete space in an experimental apparatus (CMO:0000960)33851780383517803Rat
9590136Scort3Serum corticosterone level QTL 323.370.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)32824968773249687Rat
10450804Scl70Serum cholesterol level QTL 704.70.001blood LDL cholesterol amount (VT:0000181)blood low density lipoprotein cholesterol level (CMO:0000053)32071409065714090Rat
61419Cia11Collagen induced arthritis QTL 115.6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)33035677398535386Rat
61356Bp37Blood pressure QTL 373blood pressure trait (VT:0000183)systolic blood pressure (CMO:0000004)33068464275684642Rat
1358905Hrtrt17Heart rate QTL 175.90.000014heart pumping trait (VT:2000009)heart rate (CMO:0000002)31086191289878372Rat
8694196Abfw2Abdominal fat weight QTL 216.580.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)32824968773249687Rat
2301971Cm71Cardiac mass QTL 714.63heart left ventricle mass (VT:0007031)heart left ventricle weight (CMO:0000776)341874578155617519Rat
1358885Bp251Blood pressure QTL 2513.8arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)314489145121056321Rat
1354597Kidm13Kidney mass QTL 132.9kidney mass (VT:0002707)right kidney wet weight (CMO:0000082)341874578104104347Rat
2301970Bw81Body weight QTL 815.19body mass (VT:0001259)body weight (CMO:0000012)341874578155617519Rat
8552950Pigfal12Plasma insulin-like growth factor 1 level QTL 127.3blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)32824968773249687Rat
631676Cm8Cardiac mass QTL 87.030.0001aorta mass (VT:0002845)aorta weight (CMO:0000076)31695470861954708Rat
10450794Scl69Serum cholesterol level QTL 696.30.001blood LDL cholesterol amount (VT:0000181)blood low density lipoprotein cholesterol level (CMO:0000053)32071409065714090Rat
2290452Scl56Serum cholesterol level QTL 562.26blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)3191609953Rat
8694386Bw159Body weight QTL 1594.520.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)32824968773249687Rat
12879868Am6Aortic mass QTL 60.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)33142640370668733Rat
1354604Bw36Body weight QTL 362.9body mass (VT:0001259)body weight (CMO:0000012)333703347104104347Rat
631665Bw8Body weight QTL 85.5body mass (VT:0001259)body weight (CMO:0000012)350437042119183768Rat
11565451Bw177Body weight QTL 1770.002body mass (VT:0001259)body weight (CMO:0000012)33142640370668733Rat
2301400Cm68Cardiac mass QTL 680.001heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)33142640370668733Rat
1358888Bp264Blood pressure QTL 2644.43arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)314489145121056321Rat
11565452Kidm57Kidney mass QTL 570.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)33142640370668733Rat
12879866Cm94Cardiac mass QTL 940.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)33142640370668733Rat
1358186Ept2Estrogen-induced pituitary tumorigenesis QTL 28.3pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)347233430110362260Rat
12879867Cm95Cardiac mass QTL 950.047heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)33142640370668733Rat

Markers in Region
D2Jcs24  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2352,147,545 - 52,147,837 (+)MAPPERmRatBN7.2
Rnor_6.0353,584,551 - 53,584,842NCBIRnor6.0
Rnor_5.0360,202,495 - 60,202,786UniSTSRnor5.0
RGSC_v3.4349,436,175 - 49,436,466UniSTSRGSC3.4
Celera351,718,222 - 51,718,513UniSTS
Cytogenetic Map3q21UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
6 11 49 48 53 51 22 19 22 6 135 90 29 9 30 29

Sequence


Ensembl Acc Id: ENSRNOT00000048300   ⟹   ENSRNOP00000048045
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl352,126,242 - 52,213,091 (+)Ensembl
Rnor_6.0 Ensembl353,563,194 - 53,658,132 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000101680   ⟹   ENSRNOP00000090056
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl352,162,133 - 52,213,091 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000117778   ⟹   ENSRNOP00000079592
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl351,870,092 - 52,213,091 (+)Ensembl
RefSeq Acc Id: NM_201989   ⟹   NP_973718
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8372,534,186 - 72,621,056 (+)NCBI
mRatBN7.2352,126,226 - 52,213,094 (+)NCBI
Rnor_6.0353,563,245 - 53,658,113 (+)NCBI
Rnor_5.0360,181,174 - 60,274,635 (+)NCBI
RGSC_v3.4349,414,869 - 49,502,136 (+)RGD
Celera351,697,264 - 51,784,744 (+)RGD
Sequence:
RefSeq Acc Id: XM_017591688   ⟹   XP_017447177
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8372,534,175 - 72,621,056 (+)NCBI
mRatBN7.2352,126,213 - 52,213,094 (+)NCBI
Rnor_6.0353,563,207 - 53,658,113 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_973718 (Get FASTA)   NCBI Sequence Viewer  
  XP_017447177 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAQ05020 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000048045.2
  ENSRNOP00000079592.1
  ENSRNOP00000090056.1
  ENSRNOP00065021242
GenBank Protein Q71LX6 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_973718   ⟸   NM_201989
- UniProtKB: F1LMC2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017447177   ⟸   XM_017591688
- Peptide Label: isoform X1
- UniProtKB: A0A8I6ABN9 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000048045   ⟸   ENSRNOT00000048300
Ensembl Acc Id: ENSRNOP00000090056   ⟸   ENSRNOT00000101680
Ensembl Acc Id: ENSRNOP00000079592   ⟸   ENSRNOT00000117778
Protein Domains
LIM zinc-binding

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13692109
Promoter ID:EPDNEW_R2633
Type:single initiation site
Name:Xirp2_1
Description:xin actin-binding repeat containing 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0353,563,229 - 53,563,289EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1302980 AgrOrtholog
BioCyc Gene G2FUF-49527 BioCyc
Ensembl Genes ENSRNOG00000034258 Ensembl, UniProtKB/TrEMBL
  ENSRNOG00065016207 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000048300.4 UniProtKB/TrEMBL
  ENSRNOT00000101680.1 UniProtKB/TrEMBL
  ENSRNOT00000117778.1 UniProtKB/TrEMBL
  ENSRNOT00065027034 UniProtKB/Swiss-Prot
Gene3D-CATH Cysteine Rich Protein UniProtKB/TrEMBL
InterPro Actin-binding_Xin_repeat UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  XIRP1/XIRP2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Znf_LIM UniProtKB/TrEMBL
KEGG Report rno:311098 UniProtKB/Swiss-Prot
NCBI Gene 311098 ENTREZGENE
PANTHER PTHR22591 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR22591:SF1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam LIM UniProtKB/TrEMBL
  Xin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Xirp2 PhenoGen
PROSITE LIM_DOMAIN_1 UniProtKB/TrEMBL
  LIM_DOMAIN_2 UniProtKB/TrEMBL
  XIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000034258 RatGTEx
  ENSRNOG00065016207 RatGTEx
SMART LIM UniProtKB/TrEMBL
Superfamily-SCOP Glucocorticoid receptor-like (DNA-binding domain) UniProtKB/TrEMBL
UniProt A0A8I5ZNK6_RAT UniProtKB/TrEMBL
  A0A8I6ABN9 ENTREZGENE, UniProtKB/TrEMBL
  F1LMC2 ENTREZGENE, UniProtKB/TrEMBL
  Q71LX6 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-03-03 Xirp2  xin actin-binding repeat containing 2  Cmya3  cardiomyopathy associated 3  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-30 Cmya3  cardiomyopathy associated 3  LACS  L-NAME induced actin cytoskeletal protein  Symbol and Name updated 1299863 APPROVED
2005-02-14 LACS  L-NAME induced actin cytoskeletal protein      Symbol and Name status set to provisional 70820 PROVISIONAL