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31 records found for search term Trap1
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RGD IDSymbolNameDescriptionChrStartStopSpeciesAnnotationsMatchType
1346837TRAP1TNF receptor associated protein 1This gene encodes a mitochondrial chaperone protein that is member of the heat shock protein 90 (HSP90) family. The encoded protein has ATPase activity and interacts with tumor necrosis factor type I. This protein may function in regulating cellular stress responses. Alternate splicing results in mu1636580373717524Human213symbol , COSMIC , Human Proteome Mapgene, protein-coding, REVIEWED [RefSeq]
1359733Trap1TNF receptor-associated protein 1ENCODES a protein that exhibits protein kinase binding; RNA binding (ortholog); INVOLVED IN negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide; negative regulation of cellular respiration (ortholog); translational attenuation (ortholog); ASSOCIATED WITH Dis101197125912005306Rat217symbol , PhenoGengene, protein-coding, PROVISIONAL [RefSeq]
1550473Trap1TNF receptor-associated protein 1Predicted to enable several functions, including ATP binding activity; ATP hydrolysis activity; and unfolded protein binding activity. Predicted to be involved in several processes, including negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide; protein foldi1638578353895704Mouse255symbol , PhenoGen , descriptiongene, protein-coding, VALIDATED [RefSeq]
8791335Trap1TNF receptor associated protein 1ENCODES a protein that exhibits protein kinase binding (ortholog); INVOLVED IN negative regulation of cellular respiration (ortholog); negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide (ortholog); translational attenuation (ortholog); ASSOCIATED WITH DiseaNW_0049554421369747113733161Chinchilla20symbolgene, protein-coding, MODEL [RefSeq]
11999585TRAP1TNF receptor associated protein 1ENCODES a protein that exhibits ATP binding (inferred); ATP hydrolysis activity (inferred); ATP-dependent protein folding chaperone (inferred); INVOLVED IN negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide (ortholog); ASSOCIATED WITH Disease Progression (o1625784832637996Bonobo29symbolgene, protein-coding, MODEL [RefSeq]
12284570TRAP1TNF receptor associated protein 1ENCODES a protein that exhibits ATP binding (inferred); ATP hydrolysis activity (inferred); ATP-dependent protein folding chaperone (inferred); INVOLVED IN negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide (ortholog); ASSOCIATED WITH Disease Progression (o63754492937596789Dog35symbolgene, protein-coding, MODEL [RefSeq]
12664857Trap1TNF receptor associated protein 1ENCODES a protein that exhibits ATP binding (inferred); ATP hydrolysis activity (inferred); ATP-dependent protein folding chaperone (inferred); INVOLVED IN negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide (ortholog); ASSOCIATED WITH Disease Progression (oNW_004936694667687704994Squirrel29symbolgene, protein-coding, MODEL [RefSeq]
14132113TRAP1TNF receptor associated protein 1ENCODES a protein that exhibits ATP binding (inferred); ATP hydrolysis activity (inferred); ATP-dependent protein folding chaperone (inferred); INVOLVED IN negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide (ortholog); ASSOCIATED WITH Disease Progression (oPig35symbolgene, protein-coding, VALIDATED [RefSeq]
14384358Trap1Flysymbolgene, null
18723811TRAP1TNF receptor associated protein 1ENCODES a protein that exhibits ATP binding (inferred); ATP hydrolysis activity (inferred); ATP-dependent protein folding chaperone (inferred); INVOLVED IN negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide (ortholog); ASSOCIATED WITH Disease Progression (oGreen Monkey29symbolgene, protein-coding, MODEL [RefSeq]
18906383Trap1TNF receptor associated protein 1ENCODES a protein that exhibits ATP binding (inferred); ATP hydrolysis activity (inferred); ATP-dependent protein folding chaperone (inferred); INVOLVED IN negative regulation of cellular respiration (ortholog); negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen perNaked Mole-Rat27symbolgene, protein-coding, MODEL [RefSeq]
288057023trap1Tropical Clawed Frogsymbolgene, null
625832883Trap1TNF receptor associated protein 1ENCODES a protein that exhibits protein kinase binding (ortholog); INVOLVED IN negative regulation of cellular respiration (ortholog); negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide (ortholog); translational attenuation (ortholog); ASSOCIATED WITH DiseaBlack Rat20symbolgene, protein-coding, MODEL [RefSeq]
284856315trap1.LAfrican Clawed Frogsymbolgene, null
329329953trap1.SAfrican Clawed Frogsymbolgene, null
1347885HSP90B2Pheat shock protein 90 beta family member 2, pseudogenePredicted to enable several functions, including ATP binding activity; ATP hydrolysis activity; and unfolded protein binding activity. Predicted to be involved in protein folding. Predicted to be active in mitochondrial inner membrane. [provided by Alliance of Genome Resources, Jul 2025]159925752599260276Human21old_gene_symbolgene, pseudo, VALIDATED [RefSeq]
1321869TGFBRAP1transforming growth factor beta receptor associated protein 1This gene encodes a protein that binds to transforming growth factor-beta (TGF-beta) receptors and plays a role in TGF-beta signaling. The encoded protein acts as a chaprone in signaling downstream of TGF-beta. It is involved in signal-dependent association with SMAD4. The protein is also a componen2105249404105329735Human85old_gene_symbolgene, protein-coding, REVIEWED [RefSeq]
1621492Tgfbrap1transforming growth factor, beta receptor associated protein 1Predicted to enable SMAD binding activity and transforming growth factor beta receptor binding activity. Predicted to be involved in several processes, including endosomal vesicle fusion; endosome to lysosome transport; and regulation of DNA-templated transcription. Part of CORVET complex. Is expres14308636043137788Mouse90old_gene_symbolgene, protein-coding, VALIDATED [RefSeq]
16567988AC006111.3novel transcript, antisense to TRAP1Humannamegene, lncrna
16563698AC006111.2novel transcript, sense overlapping TRAP1Humannamegene, lncrna
1312537VPS39VPS39 subunit of HOPS complexThis gene encodes a protein that may promote clustering and fusion of late endosomes and lysosomes. The protein may also act as an adaptor protein that modulates the transforming growth factor-beta response by coupling the transforming growth factor-beta receptor complex to the Smad pathway. Alterna154215870142208304Human105old_gene_namegene, protein-coding, REVIEWED [RefSeq]
1589457Trap1atumor rejection antigen P1AINTERACTS WITH bisphenol AX107724102107730723Rat1symbol , PhenoGengene, protein-coding, INFERRED [RefSeq]
1614411Trap1atumor rejection antigen P1APredicted to be located in nucleus. Is expressed in embryo; embryo endoderm; future midbrain; and yolk sac. [provided by Alliance of Genome Resources, Jul 2025]X138234432138238918Mouse13symbol , PhenoGengene, protein-coding, VALIDATED [RefSeq]
1343127MED14mediator complex subunit 14The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit X4064830540736159Human106old_gene_name , old_gene_symbolgene, protein-coding, REVIEWED [RefSeq]
1617593Med14mediator complex subunit 14Predicted to enable transcription coactivator activity. Acts upstream of or within somatic stem cell population maintenance. Part of mediator complex. Is expressed in several structures, including alimentary system; brain; genitourinary system; integumental system; and sensory organ. Orthologous to X1254160712628813Mouse107old_gene_symbolgene, protein-coding, VALIDATED [RefSeq]
1348876MED24mediator complex subunit 24This gene encodes a component of the mediator complex (also known as TRAP, SMCC, DRIP, or ARC), a transcriptional coactivator complex thought to be required for the expression of almost all genes. The mediator complex is recruited by transcriptional activators or nuclear receptors to induce gene exp174001910440054408Human91old_gene_symbolgene, protein-coding, REVIEWED [RefSeq]
1620081Med24mediator complex subunit 24This gene encodes a component of the mediator complex (also known as TRAP, SMCC, DRIP, or ARC), a transcriptional coactivator complex thought to be required for the expression of almost all genes. The mediator complex is recruited by transcriptional activators or nuclear receptors to induce gene exp119859542398620245Mouse117old_gene_name , old_gene_symbolgene, protein-coding, REVIEWED [RefSeq]
1314565THRAP3thyroid hormone receptor associated protein 3Enables nuclear thyroid hormone receptor binding activity; phosphoprotein binding activity; and transcription coactivator activity. Involved in positive regulation of circadian rhythm and regulation of gene expression. Acts upstream of or within positive regulation of transcription by RNA polymerase13620763736305357Human124old_gene_symbolgene, protein-coding, VALIDATED [RefSeq]
1314566Thrap3thyroid hormone receptor associated protein 3Enables RNA polymerase II cis-regulatory region sequence-specific DNA binding activity and transcription coactivator activity. Involved in circadian rhythm. Part of mediator complex. Is expressed in several structures, including brain; branchial arch; genitourinary system; limb; and retina nuclear l4126057875126096548Mouse169old_gene_symbolgene, protein-coding, VALIDATED [RefSeq]
1306129Thrap3thyroid hormone receptor associated protein 3ENCODES a protein that exhibits nuclear thyroid hormone receptor binding (ortholog); phosphoprotein binding (ortholog); RNA polymerase II cis-regulatory region sequence-specific DNA binding (ortholog); INVOLVED IN circadian rhythm (ortholog); mRNA stabilization (ortholog); nuclear-transcribed mRNA c5143729821143772105Rat148old_gene_namegene, protein-coding, PROVISIONAL [RefSeq]
1316342HSP90AA2Pheat shock protein 90 alpha family class A member 2, pseudogeneHSP90 proteins are highly conserved molecular chaperones that have key roles in signal transduction, protein folding, protein degradation, and morphologic evolution. HSP90 proteins normally associate with other cochaperones and play important roles in folding newly synthesized proteins or stabilizin112788817127891092Human36descriptiongene, pseudo, INFERRED [RefSeq]