HSP90AA2P (heat shock protein 90 alpha family class A member 2, pseudogene) - Rat Genome Database

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Gene: HSP90AA2P (heat shock protein 90 alpha family class A member 2, pseudogene) Homo sapiens
Analyze
No known orthologs.
Symbol: HSP90AA2P
Name: heat shock protein 90 alpha family class A member 2, pseudogene
RGD ID: 1316342
HGNC Page HGNC:5256
Description: Predicted to enable ATP binding activity; disordered domain specific binding activity; and unfolded protein binding activity. Predicted to be involved in cellular response to heat; protein folding; and protein stabilization. Located in extracellular exosome.
Type: pseudo (Ensembl: processed_pseudogene)
RefSeq Status: INFERRED
Previously known as: heat shock 90kda protein 1, alpha-like 3; heat shock protein 90kDa alpha family class A member 2, pseudogene; HSP90AA2; HSP90ALPHA; HSPCA; HSPCAL3
RGD Orthologs
Alliance Genes
More Info homologs ...
Related Functional Gene: HSP90AA1  
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381127,888,171 - 27,891,092 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1127,888,838 - 27,891,033 (-)EnsemblGRCh38hg38GRCh38
GRCh371127,909,718 - 27,912,639 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361127,866,201 - 27,869,315 (-)NCBINCBI36Build 36hg18NCBI36
Celera1128,055,621 - 28,058,542 (-)NCBICelera
Cytogenetic Map11p14.1NCBI
HuRef1127,607,982 - 27,610,903 (-)NCBIHuRef
CHM1_11127,908,627 - 27,911,548 (-)NCBICHM1_1
T2T-CHM13v2.01128,028,805 - 28,031,726 (-)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. GOAs Human GO annotations GOA_HUMAN data from the GO Consortium
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:1740332   PMID:2591742   PMID:14743216   PMID:15146192   PMID:16269234   PMID:17643375   PMID:17724475   PMID:18559531   PMID:18798074   PMID:19091746   PMID:19130193   PMID:19234166  
PMID:19383717   PMID:20170530   PMID:20558142   PMID:20694586   PMID:20937816   PMID:21127066   PMID:21145461   PMID:21519806   PMID:21873635   PMID:22552610   PMID:22753480   PMID:22935040  
PMID:22939629   PMID:23533145   PMID:23589305   PMID:24981860   PMID:25031753   PMID:25243181   PMID:25287672   PMID:25996949   PMID:26651243   PMID:27114451   PMID:27591049   PMID:27721406  
PMID:28533407   PMID:29117863   PMID:29178343   PMID:29229926   PMID:29337688   PMID:29845934   PMID:29907909   PMID:30258100   PMID:30733455   PMID:31091453   PMID:31586073   PMID:31847880  
PMID:31885746   PMID:32707033   PMID:33567341   PMID:33838681   PMID:34299365   PMID:34428256   PMID:34547748   PMID:34708717   PMID:35007762   PMID:35689138   PMID:35972640   PMID:35973513  
PMID:36042349   PMID:36282215   PMID:36574265   PMID:38280407  


Genomics

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:141
Count of miRNA genes:130
Interacting mature miRNAs:135
Transcripts:ENST00000440936, ENST00000530115
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Markers in Region
RH78019  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh3714102,547,614 - 102,547,746UniSTSGRCh37
GRCh371127,909,947 - 27,910,080UniSTSGRCh37
Build 361127,866,523 - 27,866,656RGDNCBI36
Celera1482,602,103 - 82,602,235UniSTS
Celera1128,055,850 - 28,055,983RGD
Cytogenetic Map14q32.33UniSTS
Cytogenetic Map11p14.1UniSTS
HuRef1127,608,211 - 27,608,344UniSTS
HuRef1482,726,518 - 82,726,650UniSTS
GDB:201870  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh3714102,552,139 - 102,552,415UniSTSGRCh37
GRCh371127,912,096 - 27,912,372UniSTSGRCh37
Build 361127,868,672 - 27,868,948RGDNCBI36
Celera1482,606,633 - 82,606,909UniSTS
Celera1128,057,999 - 28,058,275RGD
Cytogenetic Map14q32.33UniSTS
Cytogenetic Map11p14.1UniSTS
HuRef1127,610,360 - 27,610,636UniSTS
HuRef1482,731,048 - 82,731,324UniSTS
D3S4173  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh3714102,552,133 - 102,552,238UniSTSGRCh37
GRCh371127,912,090 - 27,912,195UniSTSGRCh37
Build 361127,868,666 - 27,868,771RGDNCBI36
Celera1482,606,627 - 82,606,732UniSTS
Celera1128,057,993 - 28,058,098RGD
Cytogenetic Map14q32.33UniSTS
Cytogenetic Map11p14.1UniSTS
HuRef1127,610,354 - 27,610,459UniSTS
HuRef1482,731,042 - 82,731,147UniSTS
HSPCAL3__6605  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371127,910,222 - 27,910,860UniSTSGRCh37
GRCh3714102,547,888 - 102,549,401UniSTSGRCh37
Build 361127,866,798 - 27,867,436RGDNCBI36
Celera1482,602,379 - 82,603,892UniSTS
Celera1128,056,125 - 28,056,763RGD
HuRef1127,608,486 - 27,609,124UniSTS
HuRef1482,726,794 - 82,728,307UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system visual system adipose tissue appendage entire extraembryonic component pharyngeal arch
High
Medium 1 17 10 9 326 9 1 1 46 15 27 5 1 3
Low 575 1025 511 94 263 40 1389 587 1764 63 612 600 59 1 448 962 2 2
Below cutoff 1824 1902 1062 388 1210 283 2946 1587 1913 257 779 975 113 752 1822 2

Sequence


Reference Sequences
RefSeq Acc Id: ENST00000530115
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1127,888,838 - 27,891,033 (-)Ensembl
Protein Sequences
GenBank Protein AAA36024 (Get FASTA)   NCBI Sequence Viewer  
  Q14568 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q14568-F1-model_v2 AlphaFold Q14568 1-343 view protein structure


Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:5256 AgrOrtholog
COSMIC HSP90AA2P COSMIC
Ensembl Genes ENSG00000224411 Ensembl
Gene3D-CATH 3.30.230.80 UniProtKB/Swiss-Prot
  3.30.565.10 UniProtKB/Swiss-Prot
GTEx ENSG00000224411 GTEx
HGNC ID HGNC:5256 ENTREZGENE
Human Proteome Map HSP90AA2P Human Proteome Map
InterPro HATPase_C UniProtKB/Swiss-Prot
  HATPase_C_sf UniProtKB/Swiss-Prot
  Heat_shock_protein_90_CS UniProtKB/Swiss-Prot
  Hsp90_fam UniProtKB/Swiss-Prot
  Hsp90_N UniProtKB/Swiss-Prot
  Ribosomal_S5_D2-typ_fold UniProtKB/Swiss-Prot
NCBI Gene 3324 ENTREZGENE
OMIM 140575 OMIM
PANTHER HEAT SHOCK PROTEIN HSP 90-ALPHA UniProtKB/Swiss-Prot
  PTHR11528 UniProtKB/Swiss-Prot
Pfam HATPase_c_3 UniProtKB/Swiss-Prot
  HSP90 UniProtKB/Swiss-Prot
PRINTS HEATSHOCK90 UniProtKB/Swiss-Prot
PROSITE HSP90 UniProtKB/Swiss-Prot
SMART HATPase_c UniProtKB/Swiss-Prot
Superfamily-SCOP SSF54211 UniProtKB/Swiss-Prot
  SSF55874 UniProtKB/Swiss-Prot
UniProt HS902_HUMAN UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-06-28 HSP90AA2P  heat shock protein 90 alpha family class A member 2, pseudogene  HSP90AA2P  heat shock protein 90kDa alpha family class A member 2, pseudogene  Symbol and/or name change 5135510 APPROVED
2015-11-24 HSP90AA2P  heat shock protein 90kDa alpha family class A member 2, pseudogene  HSP90AA2P  heat shock protein 90kDa alpha (cytosolic), class A member 2, pseudogene  Symbol and/or name change 5135510 APPROVED
2014-10-15 HSP90AA2P  heat shock protein 90kDa alpha (cytosolic), class A member 2, pseudogene  HSP90AA2  heat shock protein 90kDa alpha (cytosolic), class A member 2  Symbol and/or name change 5135510 APPROVED