TRAP1 (TNF receptor associated protein 1)

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Gene: TRAP1 (TNF receptor associated protein 1) Chlorocebus sabaeus

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Symbol:

TRAP1

Name:

TNF receptor associated protein 1

RGD ID:

18723811

Description:

ENCODES a protein that exhibits ATP binding (inferred); ATP hydrolysis activity (inferred); ATP-dependent protein folding chaperone (inferred); INVOLVED IN negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide (ortholog); ASSOCIATED WITH breast carcinoma (ortholog); CAKUT (ortholog); CAKUT1 (ortholog); FOUND IN cell periphery (ortholog); mitochondrial intermembrane space (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

heat shock protein 75 kDa, mitochondrial

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

ChlSab1.1 - Green Monkey 1.1 Assembly

Position:

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	5	3,339,954 - 3,405,218 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	5	3,340,040 - 3,405,166 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666068	27,405,950 - 27,475,869 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

breast carcinoma (ISO)

CAKUT (ISO)

CAKUT1 (ISO)

Disease Progression (ISO)

epilepsy (ISO)

hereditary renal cell carcinoma (ISO)

idiopathic generalized epilepsy (ISO)

osteoarthritis (ISO)

Rubinstein-Taybi syndrome (ISO)

short-rib thoracic dysplasia 9 with or without polydactyly (ISO)

Stomach Neoplasms (ISO)

VACTERL association (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

negative regulation of cellular respiration (IEA)

negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide (ISO)

protein folding (IEA)

translational attenuation (IEA)

Cellular Component

cell periphery (IEA,ISO)

mitochondrial inner membrane (IEA)

mitochondrial intermembrane space (ISO)

mitochondrial matrix (IEA)

mitochondrion (IEA)

nucleoplasm (IEA)

Molecular Function

ATP binding (IEA)

ATP hydrolysis activity (IEA)

ATP-dependent protein folding chaperone (IEA)

protein binding (ISO)

protein kinase binding (IEA)

unfolded protein binding (IEA)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

TRAP1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	5	3,339,954 - 3,405,218 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	5	3,340,040 - 3,405,166 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666068	27,405,950 - 27,475,869 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

TRAP1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	16	3,658,037 - 3,717,524 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	16	3,651,639 - 3,717,553 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	16	3,708,038 - 3,767,525 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	16	3,648,039 - 3,707,599 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	16	3,648,039 - 3,707,514	NCBI
Celera	16	3,914,746 - 3,974,292 (-)	NCBI		Celera
Cytogenetic Map	16	p13.3	NCBI
HuRef	16	3,677,147 - 3,736,537 (-)	NCBI		HuRef
CHM1_1	16	3,708,058 - 3,767,598 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	16	3,685,304 - 3,744,794 (-)	NCBI		T2T-CHM13v2.0

Trap1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	16	3,857,835 - 3,895,704 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	16	3,857,835 - 3,895,691 (-)	Ensembl		GRCm39 Ensembl
GRCm38	16	4,039,971 - 4,077,840 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	16	4,039,971 - 4,077,827 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	16	4,039,977 - 4,077,810 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	16	3,955,205 - 3,993,038 (-)	NCBI		MGSCv36	mm8
Celera	16	4,672,290 - 4,710,127 (-)	NCBI		Celera
Cytogenetic Map	16	A1	NCBI
cM Map	16	2.38	NCBI

Trap1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	10	11,971,259 - 12,005,306 (+)	NCBI		GRCr8
mRatBN7.2	10	11,464,882 - 11,498,931 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	10	11,464,821 - 11,498,981 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	10	16,172,885 - 16,206,519 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	10	15,661,716 - 15,695,348 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	10	11,330,648 - 11,364,679 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	10	11,724,032 - 11,757,682 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	10	11,724,032 - 11,757,681 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	10	10,478,499 - 10,512,149 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	10	11,728,524 - 11,762,571 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	10	11,728,523 - 11,762,570 (+)	NCBI
Celera	10	10,421,446 - 10,455,484 (+)	NCBI		Celera
Cytogenetic Map	10	q12	NCBI

Trap1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955442	13,696,810 - 13,733,161 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955442	13,697,471 - 13,733,161 (+)	NCBI	ChiLan1.0	ChiLan1.0

TRAP1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	18	4,182,860 - 4,242,611 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	16	7,966,432 - 8,025,977 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	16	2,578,483 - 2,637,996 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	16	3,753,707 - 3,786,580 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	16	3,753,799 - 3,786,429 (-)	Ensembl	panpan1.1		panPan2

TRAP1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	6	37,544,929 - 37,596,789 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	6	37,544,580 - 37,597,427 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	6	38,873,867 - 38,925,736 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	6	37,760,017 - 37,811,929 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	6	37,759,669 - 37,812,558 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	6	37,543,278 - 37,595,139 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	6	37,436,377 - 37,488,256 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	6	37,847,123 - 37,898,963 (+)	NCBI		UU_Cfam_GSD_1.0

Trap1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024409344	106,004,468 - 106,041,800 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936694	667,691 - 704,994 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936694	667,687 - 704,994 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

TRAP1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	3	38,536,668 - 38,603,015 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	3	38,536,710 - 38,595,273 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	3	39,804,652 - 39,862,836 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

Trap1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624824	1,446,827 - 1,511,225 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624824	1,446,827 - 1,511,062 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

ectoderm	endocrine system	hemolymphoid system	mesenchyme	mesoderm	nervous system	reproductive system
76	36	20	36	36	60	20

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_007983989	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JACDXN010000036	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSCSAT00000007991 ⟹ ENSCSAP00000006150

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
ChlSab1.1 Ensembl	5	3,340,040 - 3,405,166 (-)	Ensembl

RefSeq Acc Id:

XM_007983989 ⟹ XP_007982180

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
ChlSab1.1	5	3,339,954 - 3,405,218 (-)	NCBI
Vero_WHO_p1.0	NW_023666068	27,405,950 - 27,475,869 (+)	NCBI

Sequence:

show sequence

AAAGCCCCGCCCCGCGCGGCCTCGTCCCGCCCCGTCCCATCCTGTTTGGTCCCGCGTGGCTGTG
CGCGGCGCTCTGAGAGGACGACATGGCGCGCGAGTTGCGGACGCTGTTGCTGTGGGGCCGCCGC
CTGCGGCCTCTGCTGCGGGCGCCGGCGCTGGCGGCCGCCCCGGGAGGAAAACCAATTCTGTGTC
CTCGGAGGACCGCAGCCCAGTTGGGCCCCAGGCGAAACCCGGCCTGGAGCTTCCAGGCAGGACG
GCTGTTGAGCACACAGACCGCTGAGGACAAGGAGGAGCCCCTGCACTCGATCATCAGCAGCACG
GAGAGCGTGCAGGGTTCTATTTCCAAACATGAGTTCCAGGCTGAGACAAAGAAACTTTTGGACG
TCGTTGCCCGGTCCCTGTACTCAGAAAAAGAGGTGTTTATACGGGAGCTGATCTCCAATGCCAG
CGATGCCTTGGAAAAACTGCGTCACAAACTGGTGTCTGACGGCCAAGCACTGCCAGAAATGGAG
ATTCACTTGCAGACTGATGCCGAGAAAGGAACCATCACCATCCAGGATACTGGTATTGGGATGA
CACAGGAAGAGCTGGTGTCCAACCTGGGGACTATGGCCAGATCGGGGTCAAAGGCCTTCCTGGA
CACGCTGCAGAACCAGGCTGAGGCCAGGGGCAAGATCATCGGCCAGTTTGGAGTGGGTTTCTAC
TCAGCTTTCATGGTGGCCGACAGAGTGGAGGTCTATTCCCGCTCGGCAGACCCGGGGAGCCCAG
GTTACCGGTGGCTTTCAGATGGCTCTGGAGTGTTTGAAATCGCTGAAGCTTCAGGAGTTAGAAC
CGGGACAAAAATCATCATCCACCTGAAATCCGACTGCATGGAGTTTGCTAGCGAGGCCCGGGTG
CGAGATGTGGTAGCTAAGTACAGCAACTTCGTCAGCTTCCCCTTGTACCTGAACGGAAGGCGGA
AGAACACCTTGCAGGCCATCTGGATGATGGACCCCAAGGACATCAGCGAGTGGCAACATGAGGA
GTTCTACCGCTACATCGCACAGGCTTACGACAAGCCCCGCTACACCCTGCACTATAAGACGGAC
GCGCCGCTCAACATCCGCAGCCTCTTCTACGTGCCAGATACGAAACCGTCCATGTTTGACGTGA
GCCGGGAGCTGGGCTCCAGGGTTGCACTGTACAGCCGCAAAGTCCTCATCCAGACCAAGGCCAC
GGACATTCTGCCCAAGTGGCTGCGCTTCATCCGAGGTGTGGTGGACAGTGAGGACATTCCCCTG
AACCTCAGCCGGGAGCTGCTGCAGGAGAGCATGCTCATCAGGAAACTCCGGGACGTTTTACAGC
AGAGGCTGATCAAATTCTTCATTGACCAGAGTAAAAAAGATGCTGAGAAATATGCAAAGTTTTT
TGAAGATTACGGCCTGTTCATGCGGGAGGGCATTGTGACCACCACCGAGCAGGAGGTCAAGGAG
GACATAGCAAAGCTGCTGCGCTACGAGTCCTCAGCACTGCCCGCCGGGCAGTTAACCAGCCTCT
CAGAATACGCCAGTCGCATGCGGGCCGGCACCCGCAACATCTACTACCTGTGCGCCCCCAACCG
GCACCTGGCAGAGCACTCGCCCTACTATGAGGCCATGAAGAAGAAAGACACAGAGGTTCTCTTC
TGCTATGAGCAGTTCGATGAGCTCACCCTGCTGCACCTTCGTGAGTTTGACAAGAAGCAGCTGA
TCTCCGTGGAGACGGACATCGTCGTGGATCACTACAAGGAGGAGAAGTTTGAAGACGGGTCCCC
AGCTGCCGAGCGCCTGTCAGAGGAGGAGACGGAGGAGCTCATGGCCTGGATGAGAAACGTGCTG
GGGTCGCGTGTCACCAACGTGAAGGTGACCCTCCGACTGGACACCCACCCTGCCATGGTCACCG
TGCTGGAGATGGGGGCTGCCCGCCACTTCCTGCGCATGCAGCAGCTGGCCAAGACCCAGGAGGA
GCGTGCACAGCTCCTGCAGCCCACGCTGGAGATCAACCCCAGGCATGTGCTCATCAAGAAGCTG
AATCAGCTGCGGGCAAGTGAGCCTGGCCTGGCCCAGCTGCTGGTGGATCAGATATACGAGAACG
CCATGATTGCTGCTGGGCTTGTTGACGACCCTAGGGCCATGGTGGGCCGCTTGAATGAGCTGCT
TGTCAAGGCCCTGGAGCGACACTGACAGCCAGGGGCCAGAAGGACTGATACCACAGATGACAGC
CCCGCCGCCTTGAGCTTTATTGACCTAAATTAAAAGGTATTTCTTAA

hide sequence

Protein Sequences


Protein RefSeqs	XP_007982180	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCSAP00000006150.1

RefSeq Acc Id:	XP_007982180 ⟸ XM_007983989
- UniProtKB:	A0A0D9RC11 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSCSAP00000006150 ⟸ ENSCSAT00000007991

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCSAG00000009914	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCSAT00000007991.1	UniProtKB/TrEMBL
Gene3D-CATH	1.20.120.790	UniProtKB/TrEMBL
	3.30.230.80	UniProtKB/TrEMBL
	3.30.565.10	UniProtKB/TrEMBL
	3.40.50.11260	UniProtKB/TrEMBL
InterPro	HATPase_C_sf	UniProtKB/TrEMBL
	HSP90_C	UniProtKB/TrEMBL
	Hsp90_fam	UniProtKB/TrEMBL
	Hsp90_N	UniProtKB/TrEMBL
	Ribosomal_S5_D2-typ_fold	UniProtKB/TrEMBL
KEGG Report	csab:103227549	UniProtKB/TrEMBL
NCBI Gene	TRAP1	ENTREZGENE
PANTHER	HEAT SHOCK PROTEIN 75 KDA, MITOCHONDRIAL-RELATED	UniProtKB/TrEMBL
	PTHR11528	UniProtKB/TrEMBL
Pfam	HATPase_c_3	UniProtKB/TrEMBL
	HSP90	UniProtKB/TrEMBL
PIRSF	Hsp90	UniProtKB/TrEMBL
PRINTS	HEATSHOCK90	UniProtKB/TrEMBL
Superfamily-SCOP	SSF110942	UniProtKB/TrEMBL
	SSF54211	UniProtKB/TrEMBL
	SSF55874	UniProtKB/TrEMBL
UniProt	A0A0D9RC11	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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