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31 records found for search term Tbk1
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RGD IDSymbolNameDescriptionChrStartStopSpeciesAnnotationsMatchType
1313752TBK1TANK binding kinase 1The NF-kappa-B (NFKB) complex of proteins is inhibited by I-kappa-B (IKB) proteins, which inactivate NFKB by trapping it in the cytoplasm. Phosphorylation of serine residues on the IKB proteins by IKB kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation and 126445212064502114Human521symbol , old_gene_name , COSMIC , Human Proteome Mapgene, protein-coding, REVIEWED [RefSeq]
1313753Tbk1TANK-binding kinase 1Enables several functions, including identical protein binding activity; protein phosphatase binding activity; and protein serine/threonine kinase activity. Involved in several processes, including peptidyl-serine phosphorylation; positive regulation of signal transduction; and positive regulation o10121382360121422699Mouse314symbol , old_gene_name , PhenoGen , descriptiongene, protein-coding, VALIDATED [RefSeq]
1588588Tbk1TANK-binding kinase 1ENCODES a protein that exhibits identical protein binding (ortholog); nucleic acid binding (ortholog); phosphoprotein binding (ortholog); INVOLVED IN activation of innate immune response (ortholog); antiviral innate immune response (ortholog); cytoplasmic pattern recognition receptor signaling pathw75896331958996357Rat241symbol , old_gene_name , PhenoGengene, protein-coding, PROVISIONAL [RefSeq]
8837653Tbk1TANK binding kinase 1ENCODES a protein that exhibits identical protein binding (ortholog); nucleic acid binding (ortholog); phosphoprotein binding (ortholog); INVOLVED IN activation of innate immune response (ortholog); antiviral innate immune response (ortholog); cytoplasmic pattern recognition receptor signaling pathwNW_0049554581121012011263632Chinchilla114symbol , old_gene_namegene, protein-coding, MODEL [RefSeq]
11674050TBK1TANK binding kinase 1ENCODES a protein that exhibits ATP binding (inferred); identical protein binding (inferred); kinase activity (inferred); INVOLVED IN activation of innate immune response (ortholog); defense response to Gram-positive bacterium (ortholog); dendritic cell proliferation (ortholog); PARTICIPATES IN Toll122441927124469164Bonobo137symbol , old_gene_namegene, protein-coding, MODEL [RefSeq]
12170633TBK1TANK binding kinase 1ENCODES a protein that exhibits ATP binding (inferred); identical protein binding (inferred); kinase activity (inferred); INVOLVED IN activation of innate immune response (ortholog); defense response to Gram-positive bacterium (ortholog); dendritic cell proliferation (ortholog); PARTICIPATES IN Toll1071696647208890Dog136symbol , old_gene_namegene, protein-coding, MODEL [RefSeq]
12621496Tbk1TANK binding kinase 1ENCODES a protein that exhibits ATP binding (inferred); identical protein binding (inferred); kinase activity (inferred); INVOLVED IN activation of innate immune response (ortholog); defense response to Gram-positive bacterium (ortholog); dendritic cell proliferation (ortholog); PARTICIPATES IN TollNW_00493654527637552809229Squirrel136symbol , old_gene_namegene, protein-coding, MODEL [RefSeq]
14254958TBK1TANK binding kinase 1ENCODES a protein that exhibits ATP binding (inferred); identical protein binding (inferred); kinase activity (inferred); INVOLVED IN activation of innate immune response (ortholog); defense response to Gram-positive bacterium (ortholog); dendritic cell proliferation (ortholog); PARTICIPATES IN TollPig140symbol , old_gene_namegene, protein-coding, PROVISIONAL [RefSeq]
18420397TBK1TANK binding kinase 1ENCODES a protein that exhibits ATP binding (inferred); identical protein binding (inferred); kinase activity (inferred); INVOLVED IN activation of innate immune response (ortholog); defense response to Gram-positive bacterium (ortholog); dendritic cell proliferation (ortholog); PARTICIPATES IN TollGreen Monkey136symbol , old_gene_namegene, protein-coding, MODEL [RefSeq]
18936363Tbk1TANK binding kinase 1ENCODES a protein that exhibits identical protein binding (ortholog); nucleic acid binding (ortholog); phosphoprotein binding (ortholog); INVOLVED IN activation of innate immune response (ortholog); antiviral innate immune response (ortholog); cytoplasmic pattern recognition receptor signaling pathwNaked Mole-Rat129symbol , old_gene_namegene, protein-coding, MODEL [RefSeq]
155247120tbk1Tropical Clawed Frogsymbolgene, null
626138227Tbk1TANK binding kinase 1ENCODES a protein that exhibits identical protein binding (ortholog); nucleic acid binding (ortholog); phosphoprotein binding (ortholog); INVOLVED IN activation of innate immune response (ortholog); antiviral innate immune response (ortholog); cytoplasmic pattern recognition receptor signaling pathwBlack Rat114symbol , old_gene_namegene, protein-coding, MODEL [RefSeq]
155247119tbk1.LAfrican Clawed Frogsymbolgene, null
155258319tbk1.SAfrican Clawed Frogsymbolgene, null
631328Tbkbp1TBK1 binding protein 1ENCODES a protein that exhibits metal ion binding (inferred); zinc ion binding (inferred); INVOLVED IN immune system process (inferred); innate immune response (inferred); PARTICIPATES IN Retinoic acid-inducible gene (RIG) I-like receptor signaling pathway; ASSOCIATED WITH ankylosing spondylitis (or108261697882632169Rat69old_gene_name , namegene, protein-coding, PROVISIONAL [RefSeq]
731934TBKBP1TBK1 binding protein 1TBKBP1 is an adaptor protein that binds to TBK1 (MIM 604834) and is part of the interaction network in the TNF (MIM 191160)/NFKB (see MIM 164011) pathway (Bouwmeester et al., 2004 [PubMed 14743216]).[supplied by OMIM, Mar 2008]174769406347712063Human74old_gene_name , name , descriptiongene, protein-coding, VALIDATED [RefSeq]
731935Tbkbp1TBK1 binding protein 1Predicted to enable zinc ion binding activity. Predicted to be involved in innate immune response. Predicted to be active in cytoplasm. Is expressed in brown fat; genitourinary system; and nervous system. Orthologous to human TBKBP1 (TBK1 binding protein 1). [pr119702699797042332Mouse74old_gene_name , name , descriptiongene, protein-coding, VALIDATED [RefSeq]
8977750Tbkbp1TBK1 binding protein 1ASSOCIATED WITH ankylosing spondylitis (ortholog)NW_0049554511334466113358590Chinchilla7namegene, protein-coding, MODEL [RefSeq]
11909450TBKBP1TBK1 binding protein 1ASSOCIATED WITH ankylosing spondylitis (ortholog)1798250509843029Bonobo7namegene, protein-coding, MODEL [RefSeq]
12278492TBKBP1TBK1 binding protein 1ENCODES a protein that exhibits metal ion binding (inferred); zinc ion binding (inferred); ASSOCIATED WITH ankylosing spondylitis (ortholog)92404048424055038Dog10namegene, protein-coding, MODEL [RefSeq]
12677234Tbkbp1TBK1 binding protein 1ENCODES a protein that exhibits metal ion binding (inferred); zinc ion binding (inferred); ASSOCIATED WITH ankylosing spondylitis (ortholog); FOUND IN cytoplasm (inferred)NW_0049364901357952313596325Squirrel10namegene, protein-coding, MODEL [RefSeq]
14060863TBKBP1TBK1 binding protein 1ENCODES a protein that exhibits kinase activity (inferred); metal ion binding (inferred); zinc ion binding (inferred); ASSOCIATED WITH ankylosing spondylitis (ortholog); INTERACTS WITH deoxynivalenolPig11namegene, protein-coding, MODEL [RefSeq]
18766060TBKBP1TBK1 binding protein 1ENCODES a protein that exhibits metal ion binding (inferred); zinc ion binding (inferred); ASSOCIATED WITH ankylosing spondylitis (ortholog); FOUND IN cytoplasm (inferred)Green Monkey10namegene, protein-coding, MODEL [RefSeq]
18922055Tbkbp1TBK1 binding protein 1ENCODES a protein that exhibits kinase activity (inferred); metal ion binding (inferred); zinc ion binding (inferred); ASSOCIATED WITH ankylosing spondylitis (ortholog); FOUND IN cytoplasm (inferred)Naked Mole-Rat11namegene, protein-coding, MODEL [RefSeq]
625867202Tbkbp1TBK1 binding protein 1ASSOCIATED WITH ankylosing spondylitis (ortholog)Black Rat7namegene, protein-coding, MODEL [RefSeq]
16568374AC135279.3novel transcript, antisense to TBK1Humannamegene, lncrna
1606546CC2D1Acoiled-coil and C2 domain containing 1AThis gene encodes a transcriptional repressor that binds to a conserved 14-bp 5'-repressor element and regulates expression of the 5-hydroxytryptamine (serotonin) receptor 1A gene in neuronal cells. The DNA binding and transcriptional repressor activities of the protein are inhibited by calcium. A m191390620113930879Human147old_gene_namegene, protein-coding, REVIEWED [RefSeq]
598150691tbk1lTropical Clawed Frogsymbolgene, null
598152737tbk1lTropical Clawed Frogsymbolgene, null
1605352AZI25-azacytidine induced 2AZI2, or NAP1, contributes to the activation of NFKB (see MIM 164011)-dependent gene expression by activating IKK-related kinases, such as NAK (TBK1; MIM 604834) (Fujita et al., 2003 [PubMed 14560022]).[supplied by OMIM, Mar 2008]32832104728348824Human82descriptiongene, protein-coding, VALIDATED [RefSeq]
1602207SIKE1suppressor of IKBKE 1SIKE interacts with IKK-epsilon (IKBKE; MIM 605048) and TBK1 (MIM 604834) and acts as a suppressor of TLR3 (MIM 603029) and virus-triggered interferon activation pathways (Huang et al., 2005 [PubMed 16281057]).[supplied by OMIM, Mar 2008]1114769479114780685Human54descriptiongene, protein-coding, VALIDATED [RefSeq]