Stx1a Gene Search Result

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14 records found for search term Stx1a

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RGD ID	Symbol	Name	Description	Chr	Start	Stop	Species	Annotations	Match	Type
69430	Stx1a	syntaxin 1A	ENCODES a protein that exhibits ATP-dependent protein binding; calcium-dependent protein binding; myosin binding; INVOLVED IN modulation of excitatory postsynaptic potential; positive regulation of calcium ion-dependent exocytosis; positive regulation of catecholamine secretion; PARTICIPATES IN insu ... (more) lin secretion pathway; ASSOCIATED WITH autistic disorder (ortholog); Creutzfeldt-Jakob disease (ortholog); disease of mental health (ortholog); FOUND IN actomyosin; glutamatergic synapse; plasma membrane; INTERACTS WITH (S)-amphetamine; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil	12	27278517	27306547	Rat	329	symbol , PhenoGen	gene, protein-coding, PROVISIONAL [RefSeq]
69485	STX1A	syntaxin 1A	This gene encodes a member of the syntaxin superfamily. Syntaxins are nervous system-specific proteins implicated in the docking of synaptic vesicles with the presynaptic plasma membrane. Syntaxins possess a single C-terminal transmembrane domain, a SNARE [Soluble NSF (N-ethylmaleimide-sensitive fus ... (more) ion protein)-Attachment protein REceptor] domain (known as H3), and an N-terminal regulatory domain (Habc). Syntaxins bind synaptotagmin in a calcium-dependent fashion and interact with voltage dependent calcium and potassium channels via the C-terminal H3 domain. This gene product is a key molecule in ion channel regulation and synaptic exocytosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Sep 2009]	7	73699210	73719669	Human	476	symbol , COSMIC , Human Proteome Map	gene, protein-coding, REVIEWED [RefSeq]
69486	Stx1a	syntaxin 1A (brain)	Enables SNARE binding activity and calcium channel inhibitor activity. Involved in several processes, including modulation of chemical synaptic transmission; regulation of synaptic vesicle priming; and signal release. Acts upstream of or within calcium-ion regulated exocytosis. Located in several ce ... (more) llular components, including axon; nuclear membrane; and secretory vesicle. Part of synaptobrevin 2-SNAP-25-syntaxin-1a complex. Is expressed in several structures, including adrenal gland; male reproductive gland or organ; nervous system; retina; and skeletal muscle. Used to study disease of mental health. Human ortholog(s) of this gene implicated in Creutzfeldt-Jakob disease and Hirschsprung's disease. Orthologous to human STX1A (syntaxin 1A). [provided by Alliance of Genome Resources, Jul 2025]	5	135051473	135079954	Mouse	353	symbol , PhenoGen , description	gene, protein-coding, VALIDATED [RefSeq]
8828511	Stx1a	syntaxin 1A	ENCODES a protein that exhibits ATP-dependent protein binding (ortholog); calcium channel inhibitor activity (ortholog); calcium-dependent protein binding (ortholog); INVOLVED IN calcium-ion regulated exocytosis (ortholog); hormone secretion (ortholog); insulin secretion (ortholog); PARTICIPATES IN ... (more) insulin secretion pathway; ASSOCIATED WITH autistic disorder (ortholog); Creutzfeldt-Jakob disease (ortholog); disease of mental health (ortholog); FOUND IN acrosomal vesicle (ortholog); actomyosin (ortholog); axon (ortholog)	NW_004955456	14030233	14046456	Chinchilla	179	symbol	gene, protein-coding, MODEL [RefSeq]
12251021	STX1A	syntaxin 1A	ENCODES a protein that exhibits ATP-dependent protein binding (ortholog); calcium channel inhibitor activity (ortholog); calcium-dependent protein binding (ortholog); INVOLVED IN calcium-ion regulated exocytosis (ortholog); hormone secretion (ortholog); insulin secretion (ortholog); PARTICIPATES IN ... (more) insulin secretion pathway; ASSOCIATED WITH autistic disorder (ortholog); Creutzfeldt-Jakob disease (ortholog); disease of mental health (ortholog); FOUND IN acrosomal vesicle (ortholog); actomyosin (ortholog); axon (ortholog)	6	6574616	6583002	Dog	184	symbol	gene, protein-coding, MODEL [RefSeq]
12730390	Stx1a	syntaxin 1A	ENCODES a protein that exhibits ATP-dependent protein binding (ortholog); calcium-dependent protein binding (ortholog); myosin binding (ortholog); INVOLVED IN calcium-ion regulated exocytosis (ortholog); modulation of excitatory postsynaptic potential (ortholog); positive regulation of calcium ion-d ... (more) ependent exocytosis (ortholog); PARTICIPATES IN insulin secretion pathway; ASSOCIATED WITH autistic disorder (ortholog); Creutzfeldt-Jakob disease (ortholog); disease of mental health (ortholog); FOUND IN acrosomal vesicle (ortholog); actomyosin (ortholog); glutamatergic synapse (ortholog)	NW_004936543	2909560	2918175	Squirrel	185	symbol	gene, protein-coding, MODEL [RefSeq]
18920928	Stx1a	syntaxin 1A	ENCODES a protein that exhibits ATP-dependent protein binding (ortholog); calcium channel inhibitor activity (ortholog); calcium-dependent protein binding (ortholog); INVOLVED IN calcium-ion regulated exocytosis (ortholog); hormone secretion (ortholog); insulin secretion (ortholog); PARTICIPATES IN ... (more) insulin secretion pathway; ASSOCIATED WITH autistic disorder (ortholog); Creutzfeldt-Jakob disease (ortholog); disease of mental health (ortholog); FOUND IN acrosomal vesicle (ortholog); actomyosin (ortholog); axon (ortholog)				Naked Mole-Rat	183	symbol	gene, protein-coding, MODEL [RefSeq]
14001064	STX1A	syntaxin 1A	ENCODES a protein that exhibits protein domain specific binding (ortholog); protein kinase binding (ortholog); signaling receptor binding (ortholog); INVOLVED IN calcium ion-regulated exocytosis of neurotransmitter (ortholog); negative regulation of synaptic vesicle recycling (ortholog); positive re ... (more) gulation of spontaneous neurotransmitter secretion (ortholog); ASSOCIATED WITH autistic disorder (ortholog); Creutzfeldt-Jakob disease (ortholog); Duchenne muscular dystrophy (ortholog); FOUND IN neuromuscular junction (ortholog); presynapse (ortholog); presynaptic active zone membrane (ortholog); INTERACTS WITH deoxynivalenol				Pig	92	symbol	gene, protein-coding, MODEL [RefSeq]
155256451	stx1a						Tropical Clawed Frog		symbol	gene, null
18558032	STX1A	syntaxin 1A	ENCODES a protein that exhibits ATP-dependent protein binding (ortholog); calcium-dependent protein binding (ortholog); myosin binding (ortholog); INVOLVED IN calcium-ion regulated exocytosis (ortholog); modulation of excitatory postsynaptic potential (ortholog); positive regulation of calcium ion-d ... (more) ependent exocytosis (ortholog); PARTICIPATES IN insulin secretion pathway; ASSOCIATED WITH autistic disorder (ortholog); Creutzfeldt-Jakob disease (ortholog); disease of mental health (ortholog); FOUND IN acrosomal vesicle (ortholog); actomyosin (ortholog); glutamatergic synapse (ortholog)				Green Monkey	184	symbol	gene, protein-coding, MODEL [RefSeq]
626110076	Stx1a	syntaxin 1A	ENCODES a protein that exhibits ATP-dependent protein binding (ortholog); calcium channel inhibitor activity (ortholog); calcium-dependent protein binding (ortholog); INVOLVED IN calcium-ion regulated exocytosis (ortholog); hormone secretion (ortholog); insulin secretion (ortholog); PARTICIPATES IN ... (more) insulin secretion pathway; ASSOCIATED WITH autistic disorder (ortholog); Creutzfeldt-Jakob disease (ortholog); disease of mental health (ortholog); FOUND IN acrosomal vesicle (ortholog); actomyosin (ortholog); axon (ortholog)				Black Rat	179	symbol	gene, protein-coding, MODEL [RefSeq]
11830776	STX1A	syntaxin 1A	ENCODES a protein that exhibits ATP-dependent protein binding (ortholog); calcium-dependent protein binding (ortholog); myosin binding (ortholog); INVOLVED IN calcium-ion regulated exocytosis (ortholog); modulation of excitatory postsynaptic potential (ortholog); positive regulation of calcium ion-d ... (more) ependent exocytosis (ortholog); PARTICIPATES IN insulin secretion pathway; ASSOCIATED WITH autistic disorder (ortholog); Creutzfeldt-Jakob disease (ortholog); disease of mental health (ortholog); FOUND IN acrosomal vesicle (ortholog); actomyosin (ortholog); glutamatergic synapse (ortholog)				Bonobo	186	symbol	gene, protein-coding, MODEL [RefSeq]
155258758	stx1a.L						African Clawed Frog		symbol	gene, null
155239333	stx1a.S						African Clawed Frog		symbol	gene, null