Itgav Gene Search Result

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14 records found for search term Itgav

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RGD ID	Symbol	Name	Description	Chr	Start	Stop	Species	Annotations	Match	Type
1310613	Itgav	integrin subunit alpha V	ENCODES a protein that exhibits signaling receptor binding; C-X3-C chemokine binding (ortholog); collagen binding (ortholog); INVOLVED IN angiogenesis; cell migration; positive regulation of cell population proliferation; PARTICIPATES IN integrin mediated signaling pathway; platelet-derived growth f ... (more) actor signaling pathway; sphingosine 1-phosphate signaling pathway; ASSOCIATED WITH Alveolar Bone Loss; Carotid Artery Injuries; Choroidal Neovascularization; FOUND IN alphav-beta3 integrin-HMGB1 complex (ortholog); alphav-beta3 integrin-IGF-1-IGF1R complex (ortholog); cell surface (ortholog); INTERACTS WITH 1-naphthyl isothiocyanate; 17alpha-ethynylestradiol; 17beta-estradiol	3	89245382	89333512	Rat	373	symbol , PhenoGen	gene, protein-coding, VALIDATED [RefSeq]
1321618	ITGAV	integrin subunit alpha V	The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha subunit and a beta subunit that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light a ... (more) nd heavy chains that comprise the alpha V subunit. This subunit associates with beta 1, beta 3, beta 5, beta 6 and beta 8 subunits. The heterodimer consisting of alpha V and beta 3 subunits is also known as the vitronectin receptor. This integrin may regulate angiogenesis and cancer progression. Alternative splicing results in multiple transcript variants. Note that the integrin alpha 5 and integrin alpha V subunits are encoded by distinct genes. [provided by RefSeq, Oct 2015]	2	186590056	186680901	Human	356	symbol , COSMIC , Human Proteome Map	gene, protein-coding, REVIEWED [RefSeq]
1617623	Itgav	integrin alpha V	This gene encodes a protein that is a member of the integrin superfamily. Integrins are transmembrane receptors involved cell adhesion and signaling, and they are subdivided based on the heterodimer formation of alpha and beta chains. This protein has been shown to heterodimerize with beta 1, beta 3 ... (more) , beta 6 and beta 8. The heterodimer of alpha v and beta 3 forms the Vitronectin receptor. This protein interacts with several extracellular matrix proteins to mediate cell adhesion and may play a role in cell migration. In mouse, deficiency of this gene is associated with defects in vascular morphogenesis in the brain and early post-natal death. [provided by RefSeq, May 2013]	2	83554796	83637261	Mouse	495	symbol , PhenoGen	gene, protein-coding, REVIEWED [RefSeq]
8806657	Itgav	integrin subunit alpha V	ENCODES a protein that exhibits C-X3-C chemokine binding (ortholog); collagen binding (ortholog); coreceptor activity (ortholog); INVOLVED IN angiogenesis (ortholog); apolipoprotein A-I-mediated signaling pathway (ortholog); apoptotic cell clearance (ortholog); PARTICIPATES IN integrin mediated sign ... (more) aling pathway; platelet-derived growth factor signaling pathway; sphingosine 1-phosphate signaling pathway; ASSOCIATED WITH abdominal aortic aneurysm (ortholog); acute myeloid leukemia (ortholog); Alveolar Bone Loss (ortholog); FOUND IN alphav-beta3 integrin-HMGB1 complex (ortholog); alphav-beta3 integrin-IGF-1-IGF1R complex (ortholog); cell surface (ortholog)	NW_004955403	11588536	11669809	Chinchilla	120	symbol	gene, protein-coding, MODEL [RefSeq]
11754811	ITGAV	integrin subunit alpha V	ENCODES a protein that exhibits collagen binding (ortholog); signaling receptor binding (ortholog); transforming growth factor beta binding (ortholog); INVOLVED IN angiogenesis (ortholog); apoptotic cell clearance (ortholog); blood vessel development (ortholog); PARTICIPATES IN integrin mediated sig ... (more) naling pathway; platelet-derived growth factor signaling pathway; sphingosine 1-phosphate signaling pathway; ASSOCIATED WITH abdominal aortic aneurysm (ortholog); acute myeloid leukemia (ortholog); Alveolar Bone Loss (ortholog); FOUND IN alphav-beta3 integrin-HMGB1 complex (inferred); alphav-beta3 integrin-IGF-1-IGF1R complex (inferred); cell surface (inferred)	2B	73880962	73972486	Bonobo	139	symbol	gene, protein-coding, MODEL [RefSeq]
12288715	ITGAV	integrin subunit alpha V	ENCODES a protein that exhibits collagen binding (ortholog); signaling receptor binding (ortholog); transforming growth factor beta binding (ortholog); INVOLVED IN angiogenesis (ortholog); apoptotic cell clearance (ortholog); blood vessel development (ortholog); PARTICIPATES IN integrin mediated sig ... (more) naling pathway; platelet-derived growth factor signaling pathway; sphingosine 1-phosphate signaling pathway; ASSOCIATED WITH abdominal aortic aneurysm (ortholog); acute myeloid leukemia (ortholog); Alveolar Bone Loss (ortholog); FOUND IN alphav-beta3 integrin-HMGB1 complex (inferred); alphav-beta3 integrin-IGF-1-IGF1R complex (inferred); cell surface (inferred)	36	28815215	28890569	Dog	133	symbol	gene, protein-coding, MODEL [RefSeq]
12600844	Itgav	integrin subunit alpha V	ENCODES a protein that exhibits collagen binding (ortholog); signaling receptor binding (ortholog); transforming growth factor beta binding (ortholog); INVOLVED IN angiogenesis (ortholog); apoptotic cell clearance (ortholog); blood vessel development (ortholog); PARTICIPATES IN integrin mediated sig ... (more) naling pathway; platelet-derived growth factor signaling pathway; sphingosine 1-phosphate signaling pathway; ASSOCIATED WITH abdominal aortic aneurysm (ortholog); acute myeloid leukemia (ortholog); Alveolar Bone Loss (ortholog); FOUND IN alphav-beta3 integrin-HMGB1 complex (inferred); alphav-beta3 integrin-IGF-1-IGF1R complex (inferred); cell surface (inferred)	NW_004936506	10750116	10839018	Squirrel	134	symbol	gene, protein-coding, MODEL [RefSeq]
18796818	ITGAV	integrin subunit alpha V	ENCODES a protein that exhibits collagen binding (ortholog); signaling receptor binding (ortholog); transforming growth factor beta binding (ortholog); INVOLVED IN angiogenesis (ortholog); apoptotic cell clearance (ortholog); blood vessel development (ortholog); PARTICIPATES IN integrin mediated sig ... (more) naling pathway; platelet-derived growth factor signaling pathway; sphingosine 1-phosphate signaling pathway; ASSOCIATED WITH abdominal aortic aneurysm (ortholog); acute myeloid leukemia (ortholog); Alveolar Bone Loss (ortholog); FOUND IN alphav-beta3 integrin-HMGB1 complex (inferred); alphav-beta3 integrin-IGF-1-IGF1R complex (inferred); cell surface (inferred)				Green Monkey	137	symbol	gene, protein-coding, MODEL [RefSeq]
18903000	Itgav	integrin subunit alpha V	ENCODES a protein that exhibits C-X3-C chemokine binding (ortholog); collagen binding (ortholog); coreceptor activity (ortholog); INVOLVED IN angiogenesis (ortholog); apolipoprotein A-I-mediated signaling pathway (ortholog); apoptotic cell clearance (ortholog); PARTICIPATES IN integrin mediated sign ... (more) aling pathway; platelet-derived growth factor signaling pathway; sphingosine 1-phosphate signaling pathway; ASSOCIATED WITH abdominal aortic aneurysm (ortholog); acute myeloid leukemia (ortholog); Alveolar Bone Loss (ortholog); FOUND IN alphav-beta3 integrin-HMGB1 complex (ortholog); alphav-beta3 integrin-IGF-1-IGF1R complex (ortholog); cell surface (ortholog)				Naked Mole-Rat	121	symbol	gene, protein-coding, MODEL [RefSeq]
626027469	Itgav	integrin subunit alpha V	ENCODES a protein that exhibits C-X3-C chemokine binding (ortholog); collagen binding (ortholog); coreceptor activity (ortholog); INVOLVED IN angiogenesis (ortholog); apolipoprotein A-I-mediated signaling pathway (ortholog); apoptotic cell clearance (ortholog); PARTICIPATES IN integrin mediated sign ... (more) aling pathway; platelet-derived growth factor signaling pathway; sphingosine 1-phosphate signaling pathway; ASSOCIATED WITH abdominal aortic aneurysm (ortholog); acute myeloid leukemia (ortholog); Alveolar Bone Loss (ortholog); FOUND IN alphav-beta3 integrin-HMGB1 complex (ortholog); alphav-beta3 integrin-IGF-1-IGF1R complex (ortholog); cell surface (ortholog)				Black Rat	120	symbol	gene, protein-coding, MODEL [RefSeq]
14223319	ITGAV	integrin subunit alpha V	ENCODES a protein that exhibits collagen binding; transforming growth factor beta binding; signaling receptor binding (ortholog); INVOLVED IN response to nitric oxide; angiogenesis (ortholog); apoptotic cell clearance (ortholog); PARTICIPATES IN integrin mediated signaling pathway; platelet-derived ... (more) growth factor signaling pathway; sphingosine 1-phosphate signaling pathway; ASSOCIATED WITH abdominal aortic aneurysm (ortholog); acute myeloid leukemia (ortholog); Alveolar Bone Loss (ortholog); FOUND IN cell surface; INTERACTS WITH deoxynivalenol; graphene oxide; KT 5823				Pig	144	symbol	gene, protein-coding, PROVISIONAL [RefSeq]
155256708	itgav						Tropical Clawed Frog		symbol	gene, null
155252977	itgav.L						African Clawed Frog		symbol	gene, null
616336049	FAM171B-AS1	FAM171B and ITGAV antisense RNA 1					Human		name	gene, protein-coding