| 2020 | Acp1 | acid phosphatase 1 | ENCODES a protein that exhibits acid phosphatase activity; protein tyrosine phosphatase activity; SH3 domain binding; INVOLVED IN chemical synaptic transmission; PARTICIPATES IN ephrin - ephrin receptor bidirectional signaling axis; riboflavin metabolic pathway; ASSOCIATED WITH attention deficit hyp eractivity disorder (ortholog); conduct disorder (ortholog); coronary artery disease (ortholog); FOUND IN cytoplasm (ortholog); cytoplasmic side of plasma membrane (ortholog); cytosol (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; 2,4-dinitrotoluene | 6 | 53233937 | 53249576 | Rat | 158 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 10068 | Acp1 | acid phosphatase 1, soluble | Enables acid phosphatase activity. Predicted to be involved in chromatin remodeling. Located in cytosol and sarcolemma. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; integumental system; and sensory organ. Human ortholog(s) of this gen e implicated in several diseases, including attention deficit hyperactivity disorder; conduct disorder; diabetes mellitus (multiple); diabetic retinopathy; and obesity. Orthologous to human ACP1 (acid phosphatase 1). [provided by Alliance of Genome Resources, Apr 2025] | 12 | 30943325 | 30961616 | Mouse | 165 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 10069 | ACP1 | acid phosphatase 1 | The product of this gene belongs to the phosphotyrosine protein phosphatase family of proteins. It functions as an acid phosphatase and a protein tyrosine phosphatase by hydrolyzing protein tyrosine phosphate to protein tyrosine and orthophosphate. This enzyme also hydrolyzes orthophosphoric monoest ers to alcohol and orthophosphate. This gene is genetically polymorphic, and three common alleles segregating at the corresponding locus give rise to six phenotypes. Each allele appears to encode at least two electrophoretically different isozymes, Bf and Bs, which are produced in allele-specific ratios. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Aug 2008] | 2 | 264947 | 278283 | Human | 160 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 8981568 | Acp1 | acid phosphatase 1 | ENCODES a protein that exhibits acid phosphatase activity (ortholog); phosphatase activity (ortholog); protein tyrosine phosphatase activity (ortholog); INVOLVED IN chemical synaptic transmission (ortholog); PARTICIPATES IN ephrin - ephrin receptor bidirectional signaling axis; riboflavin metabolic pathway; ASSOCIATED WITH attention deficit hyperactivity disorder (ortholog); conduct disorder (ortholog); coronary artery disease (ortholog); FOUND IN cytoplasm (ortholog); cytoplasmic side of plasma membrane (ortholog); cytosol (ortholog) | NW_004955487 | 290434 | 302405 | Chinchilla | 31 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11981057 | ACP1 | acid phosphatase 1 | ENCODES a protein that exhibits acid phosphatase activity (ortholog); protein tyrosine phosphatase activity (ortholog); SH3 domain binding (ortholog); INVOLVED IN chemical synaptic transmission (ortholog); PARTICIPATES IN ephrin - ephrin receptor bidirectional signaling axis; riboflavin metabolic pa thway; ASSOCIATED WITH attention deficit hyperactivity disorder (ortholog); conduct disorder (ortholog); coronary artery disease (ortholog); FOUND IN cytoplasmic side of plasma membrane (ortholog); cytosol (ortholog); sarcolemma (ortholog) | 2A | 257892 | 271320 | Bonobo | 40 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12286527 | ACP1 | acid phosphatase 1 | ENCODES a protein that exhibits acid phosphatase activity (ortholog); phosphatase activity (ortholog); protein tyrosine phosphatase activity (ortholog); INVOLVED IN chemical synaptic transmission (ortholog); PARTICIPATES IN ephrin - ephrin receptor bidirectional signaling axis; riboflavin metabolic pathway; ASSOCIATED WITH attention deficit hyperactivity disorder (ortholog); conduct disorder (ortholog); coronary artery disease (ortholog); FOUND IN cytoplasmic side of plasma membrane (ortholog); cytosol (ortholog); sarcolemma (ortholog) | 17 | 243757 | 251151 | Dog | 40 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12519993 | Acp1 | acid phosphatase 1 | ENCODES a protein that exhibits acid phosphatase activity (ortholog); protein tyrosine phosphatase activity (ortholog); SH3 domain binding (ortholog); INVOLVED IN chemical synaptic transmission (ortholog); PARTICIPATES IN ephrin - ephrin receptor bidirectional signaling axis; riboflavin metabolic pa thway; ASSOCIATED WITH attention deficit hyperactivity disorder (ortholog); conduct disorder (ortholog); coronary artery disease (ortholog); FOUND IN cytoplasm (inferred); cytoplasmic side of plasma membrane (inferred); cytosol (inferred) | NW_004936532 | 130799 | 145285 | Squirrel | 43 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 14245162 | ACP1 | acid phosphatase 1 | ENCODES a protein that exhibits acid phosphatase activity (ortholog); protein tyrosine phosphatase activity (ortholog); SH3 domain binding (ortholog); INVOLVED IN chemical synaptic transmission (ortholog); PARTICIPATES IN ephrin - ephrin receptor bidirectional signaling axis; riboflavin metabolic pa thway; ASSOCIATED WITH attention deficit hyperactivity disorder (ortholog); conduct disorder (ortholog); coronary artery disease (ortholog); FOUND IN cytoplasm (inferred); cytoplasmic side of plasma membrane (inferred); cytosol (inferred) | | | | Pig | 45 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 14375182 | ACP1 | | | | | | Yeast | | symbol | gene, null |
| 18660405 | ACP1 | acid phosphatase 1 | ENCODES a protein that exhibits acid phosphatase activity (ortholog); phosphatase activity (ortholog); protein tyrosine phosphatase activity (ortholog); INVOLVED IN chemical synaptic transmission (ortholog); PARTICIPATES IN ephrin - ephrin receptor bidirectional signaling axis; riboflavin metabolic pathway; ASSOCIATED WITH attention deficit hyperactivity disorder (ortholog); conduct disorder (ortholog); coronary artery disease (ortholog); FOUND IN cytoplasm (ortholog); cytoplasmic side of plasma membrane (ortholog); cytosol (ortholog) | | | | Green Monkey | 31 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18900913 | Acp1 | acid phosphatase 1 | ENCODES a protein that exhibits acid phosphatase activity (ortholog); phosphatase activity (ortholog); protein tyrosine phosphatase activity (ortholog); INVOLVED IN chemical synaptic transmission (ortholog); PARTICIPATES IN ephrin - ephrin receptor bidirectional signaling axis; riboflavin metabolic pathway; ASSOCIATED WITH attention deficit hyperactivity disorder (ortholog); conduct disorder (ortholog); coronary artery disease (ortholog); FOUND IN cytoplasmic side of plasma membrane (ortholog); cytosol (ortholog); sarcolemma (ortholog) | | | | Naked Mole-Rat | 40 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 126907413 | ACP1 | acid phosphatase 1 | ENCODES a protein that exhibits acid phosphatase activity (inferred); hydrolase activity (inferred); non-membrane spanning protein tyrosine phosphatase activity (inferred); FOUND IN cytoplasm (inferred); cytoplasmic side of plasma membrane (inferred); cytosol (inferred) | | | | Green Monkey | 20 | symbol | gene, protein-coding |
| 155231966 | acp1 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 625984236 | Acp1 | acid phosphatase 1 | ENCODES a protein that exhibits acid phosphatase activity (ortholog); phosphatase activity (ortholog); protein tyrosine phosphatase activity (ortholog); INVOLVED IN chemical synaptic transmission (ortholog); PARTICIPATES IN ephrin - ephrin receptor bidirectional signaling axis; riboflavin metabolic pathway; ASSOCIATED WITH attention deficit hyperactivity disorder (ortholog); conduct disorder (ortholog); coronary artery disease (ortholog); FOUND IN cytoplasm (ortholog); cytoplasmic side of plasma membrane (ortholog); cytosol (ortholog) | | | | Black Rat | 31 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155256469 | acp1.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 155231965 | acp1.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 2320876 | Acp1-ps1 | acid phosphatase 1, pseudogene 1 | | 6 | 93800929 | 93802305 | Rat | | symbol , PhenoGen | gene, pseudo, INFERRED [RefSeq] |
| 41173474 | Acp1-ps3 | acid phosphatase 1, pseudogene 3 | | 6 | 116388139 | 116397346 | Rat | | symbol , PhenoGen | gene, pseudo, MODEL [RefSeq] |
| 1313754 | NDUFAB1 | NADH:ubiquinone oxidoreductase subunit AB1 | Enables mitochondrial large ribosomal subunit binding activity. Involved in [2Fe-2S] cluster assembly and protein lipoylation. Located in mitochondrial inner membrane and nucleoplasm. Part of mitochondrial [2Fe-2S] assembly complex and respiratory chain complex I. [provided by Alliance of Genome Res ources, Apr 2025] | 16 | 23581014 | 23596316 | Human | 176 | old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 1623696 | Gm1866 | predicted gene 1866 | | X | 113500829 | 113502246 | Mouse | | old_gene_symbol | gene, pseudo, INFERRED [RefSeq] |
| 16556588 | AC022028.1 | acid phosphatase 1, soluble (ACP1) pseudogene | | | | | Human | | name | gene, processed_pseudogene |
| 16559925 | AC112191.1 | acid phosphatase 1, soluble (ACP1) pseudogene | | | | | Human | | name | gene, processed_pseudogene |
| 16565651 | AC136443.5 | acid phosphatase 1, soluble (ACP1) pseudogene | | | | | Human | | name | gene, processed_pseudogene |
| 16563655 | AC136618.2 | acid phosphatase 1, soluble (ACP1) pseudogene | | | | | Human | | name | gene, processed_pseudogene |
| 16563665 | AC136624.3 | acid phosphatase 1, soluble (ACP1) pseudogene | | | | | Human | | name | gene, processed_pseudogene |
| 16553208 | AL663058.1 | acid phosphatase 1, soluble (ACP1) pseudogene | | | | | Human | | name | gene, processed_pseudogene |
| 1565965 | Acp1l1 | acid phosphatase 1 like 1 | INTERACTS WITH ammonium chloride | X | 10523951 | 10524559 | Rat | 1 | symbol , PhenoGen | gene, protein-coding, MODEL [RefSeq] |
| 1582722 | Acp1l2 | acid phosphatase 1 like 2 | | 1 | 79989963 | 79990394 | Rat | | symbol , PhenoGen | gene, protein-coding, MODEL [RefSeq] |
| 1317203 | Apobec3 | apolipoprotein B mRNA editing enzyme, catalytic polypeptide 3 | Predicted to enable several functions, including cytidine deaminase activity; identical protein binding activity; and zinc ion binding activity. Involved in negative regulation of viral genome replication and transposable element silencing. Acts upstream of or within hematopoietic progenitor cell di fferentiation; regulation of defense response to virus; and regulation of viral life cycle. Located in cytoplasm. Is expressed in several structures, including alimentary system; brain; genitourinary system; heart; and sensory organ. Orthologous to several human genes including APOBEC3B (apolipoprotein B mRNA editing enzyme catalytic subunit 3B); APOBEC3D (apolipoprotein B mRNA editing enzyme catalytic subunit 3D); and APOBEC3F (apolipoprotein B mRNA editing enzyme catalytic subunit 3F). [provided by Alliance of Genome Resources, Apr 2025] | 15 | 79774620 | 79802419 | Mouse | 82 | GenBank Protein | gene, protein-coding, VALIDATED [RefSeq] |
| 14205402 | CLDN12 | claudin 12 | INVOLVED IN tight junction assembly (ortholog); FOUND IN cell periphery (ortholog); lateral plasma membrane (ortholog); tight junction (ortholog) | | | | Pig | 8 | GenBank Protein | gene, protein-coding, PROVISIONAL [RefSeq] |
| 13926901 | CLDN17 | claudin 17 | ENCODES a protein that exhibits paracellular tight junction channel activity (ortholog); INVOLVED IN cellular respiration (ortholog); gene expression (ortholog); inflammatory response (ortholog); FOUND IN tight junction (ortholog) | | | | Pig | 35 | GenBank Protein | gene, protein-coding, PROVISIONAL [RefSeq] |
| 13932853 | CLDN18 | claudin 18 | ENCODES a protein that exhibits structural molecule activity (inferred); INVOLVED IN digestive tract development (ortholog); negative regulation of bone resorption (ortholog); negative regulation of osteoclast development (ortholog); ASSOCIATED WITH asthma (ortholog); megacolon (ortholog); FOUND IN bicellular tight junction (inferred); cell-cell junction (inferred); membrane (inferred) | | | | Pig | 34 | GenBank Protein | gene, protein-coding, PROVISIONAL [RefSeq] |
| 14101637 | CLDN19 | claudin 19 | ENCODES a protein that exhibits identical protein binding (ortholog); INVOLVED IN apical junction assembly (ortholog); neuronal action potential propagation (ortholog); tight junction organization (ortholog); ASSOCIATED WITH genetic disease (ortholog); nephrocalcinosis (ortholog); renal hypomagnesem ia 3 (ortholog); FOUND IN apical junction complex (inferred); basolateral plasma membrane (inferred); bicellular tight junction (inferred) | | | | Pig | 57 | GenBank Protein | gene, protein-coding, PROVISIONAL [RefSeq] |
| 13975249 | CLDN20 | claudin 20 | ENCODES a protein that exhibits structural molecule activity (inferred); FOUND IN bicellular tight junction (inferred); membrane (inferred); plasma membrane (inferred) | | | | Pig | 12 | GenBank Protein | gene, protein-coding, PROVISIONAL [RefSeq] |
| 14096888 | CLDN22 | claudin 22 | ENCODES a protein that exhibits structural molecule activity (inferred); FOUND IN bicellular tight junction (inferred); membrane (inferred); plasma membrane (inferred) | | | | Pig | 10 | GenBank Protein | gene, protein-coding, PROVISIONAL [RefSeq] |
| 14197689 | CLDN23 | claudin 23 | ENCODES a protein that exhibits structural molecule activity (inferred); INVOLVED IN intracellular protein localization (ortholog); tight junction organization (ortholog); ASSOCIATED WITH atopic dermatitis (ortholog); FOUND IN bicellular tight junction (inferred); membrane (inferred); plasma membran e (inferred) | | | | Pig | 11 | GenBank Protein | gene, protein-coding, PROVISIONAL [RefSeq] |
| 13921538 | CLDN3 | claudin 3 | ENCODES a protein that exhibits cell-cell adhesion mediator activity (ortholog); identical protein binding (ortholog); INVOLVED IN actin cytoskeleton organization (ortholog); bicellular tight junction assembly (ortholog); calcium-independent cell-cell adhesion (ortholog); ASSOCIATED WITH allergic rh initis (ortholog); autism spectrum disorder (ortholog); Intestinal Reperfusion Injury (ortholog); FOUND IN apical junction complex (ortholog); apicolateral plasma membrane (ortholog); bicellular tight junction (ortholog); INTERACTS WITH 4-phenylbutyric acid; amino acid; benzo[a]pyrene | | | | Pig | 70 | GenBank Protein | gene, protein-coding, PROVISIONAL [RefSeq] |
| 14146129 | CLDN7 | claudin 7 | ENCODES a protein that exhibits cell adhesion molecule binding (ortholog); protein domain specific binding (ortholog); INVOLVED IN negative regulation of apoptotic process (ortholog); negative regulation of cell adhesion (ortholog); negative regulation of protein-containing complex assembly (ortholo g); ASSOCIATED WITH allergic rhinitis (ortholog); COVID-19 (ortholog); Neoplasm Metastasis (ortholog); FOUND IN basolateral plasma membrane (ortholog); lateral plasma membrane (ortholog); INTERACTS WITH deoxynivalenol | | | | Pig | 36 | GenBank Protein | gene, protein-coding, PROVISIONAL [RefSeq] |
| 737518 | CRYAB | crystallin alpha B | Mammalian lens crystallins are divided into alpha, beta, and gamma families. Alpha crystallins are composed of two gene products: alpha-A and alpha-B, for acidic and basic, respectively. Alpha crystallins can be induced by heat shock and are members of the small heat shock protein (HSP20) family. Th ey act as molecular chaperones although they do not renature proteins and release them in the fashion of a true chaperone; instead they hold them in large soluble aggregates. These heterogeneous aggregates consist of 30-40 subunits; the alpha-A and alpha-B subunits have a 3:1 ratio, respectively. Two additional functions of alpha crystallins are an autokinase activity and participation in the intracellular architecture. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. Alpha-A and alpha-B gene products are differentially expressed; alpha-A is preferentially restricted to the lens and alpha-B is expressed widely in many tissues and organs. Elevated expression of alpha-B crystallin occurs in many neurological diseases; a missense mutation cosegregated in a family with a desmin-related myopathy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2019] | 11 | 111908564 | 111923740 | Human | 650 | GenBank Protein | gene, protein-coding, REVIEWED [RefSeq] |
| 14177130 | SIRT2 | sirtuin 2 | ENCODES a protein that exhibits histone deacetylase activity, NAD-dependent (ortholog); tubulin deacetylase activity (ortholog); INVOLVED IN chromatin organization (ortholog); negative regulation of apoptotic process (ortholog); negative regulation of NLRP3 inflammasome complex assembly (ortholog); PARTICIPATES IN histone modification pathway; Sirtuin mediated pathway; ASSOCIATED WITH Acute Lung Injury (ortholog); cocaine dependence (ortholog); high grade glioma (ortholog); FOUND IN glial cell projection (ortholog); glutamatergic synapse (ortholog); heterochromatin (ortholog); INTERACTS WITH deoxynivalenol | | | | Pig | 155 | GenBank Protein | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1359566 | Taar3 | trace amine-associated receptor 3 | ENCODES a protein that exhibits trace-amine receptor activity (ortholog); INVOLVED IN sensory perception of chemical stimulus (ortholog); FOUND IN membrane (inferred); plasma membrane (inferred); INTERACTS WITH 17beta-estradiol; bisphenol A; 2,3,7,8-tetrachlorodibenzodioxine (ortholog) | 1 | 23310776 | 23311804 | Rat | 23 | GenBank Protein | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1552316 | Taar3 | trace amine-associated receptor 3 | Enables trace-amine receptor activity. Involved in sensory perception of chemical stimulus. Predicted to be located in membrane. Predicted to be active in plasma membrane. Is expressed in olfactory epithelium. Orthologous to human TAAR3P (trace amine associated receptor 3, pseudogene). [provided by Alliance of Genome Resources, Jul 2025] | 10 | 23825456 | 23826487 | Mouse | 31 | GenBank Protein | gene, protein-coding, PROVISIONAL [RefSeq] |
| 631382 | Taar4 | trace amine-associated receptor 4 | ENCODES a protein that exhibits G protein-coupled amine receptor activity; trace-amine receptor activity; INVOLVED IN G protein-coupled receptor signaling pathway (inferred); signal transduction (inferred); FOUND IN membrane (inferred); plasma membrane (inferred); INTERACTS WITH copper atom; copper( 0) | 1 | 23300288 | 23301331 | Rat | 19 | GenBank Protein | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1550330 | Taar4 | trace amine-associated receptor 4 | Enables 2-phenylethylamine receptor activity and trace-amine receptor activity. Involved in behavioral fear response; chemosensory behavior; and sensory perception of chemical stimulus. Predicted to be active in plasma membrane. Is expressed in Grueneberg ganglion; nasal septum; and olfactory epithe lium. Orthologous to human TAAR4P (trace amine associated receptor 4, pseudogene). [provided by Alliance of Genome Resources, Apr 2025] | 10 | 23836392 | 23837435 | Mouse | 33 | GenBank Protein | gene, protein-coding, PROVISIONAL [RefSeq] |
| 12359182 | TAAR4 | trace amine-associated receptor 4 | ENCODES a protein that exhibits G protein-coupled amine receptor activity (ortholog); INVOLVED IN adenylate cyclase-activating G protein-coupled receptor signaling pathway (ortholog); adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway (ortholog); G protein-coupled receptor sig naling pathway (ortholog); ASSOCIATED WITH schizophrenia (ortholog); FOUND IN endomembrane system (ortholog) | | | | Dog | 25 | GenBank Protein | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1359185 | Taar5 | trace amine-associated receptor 5 | ENCODES a protein that exhibits trace-amine receptor activity; trimethylamine receptor activity (ortholog); INVOLVED IN adenylate cyclase-activating G protein-coupled receptor signaling pathway (ortholog); cognition (ortholog); sensory perception of chemical stimulus (ortholog); FOUND IN plasma memb rane (ortholog); INTERACTS WITH indole-3-methanol; N-nitrosodiethylamine; (+)-catechin (ortholog) | 1 | 23289163 | 23290176 | Rat | 49 | GenBank Protein | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1552024 | Taar5 | trace amine-associated receptor 5 | Enables trimethylamine receptor activity. Involved in adenylate cyclase-activating G protein-coupled receptor signaling pathway; cognition; and sensory perception of chemical stimulus. Predicted to be located in membrane. Predicted to be active in plasma membrane. Is expressed in Grueneberg ganglion ; endolymphatic duct; nasal septum; olfactory epithelium; and utricle. Orthologous to human TAAR5 (trace amine associated receptor 5). [provided by Alliance of Genome Resources, Jul 2025] | 10 | 23846604 | 23847617 | Mouse | 49 | GenBank Protein | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1603706 | TAAR5 | trace amine associated receptor 5 | Enables trimethylamine receptor activity. Involved in adenylate cyclase-activating G protein-coupled receptor signaling pathway. Is active in plasma membrane. [provided by Alliance of Genome Resources, Jul 2025] | 6 | 132588592 | 132616747 | Human | 42 | GenBank Protein | gene, protein-coding, VALIDATED [RefSeq] |
| 12075132 | TAAR5 | trace amine associated receptor 5 | ENCODES a protein that exhibits G protein-coupled receptor activity (inferred); trace-amine receptor activity (inferred); transmembrane signaling receptor activity (inferred); INVOLVED IN adenylate cyclase-activating G protein-coupled receptor signaling pathway (inferred); cell surface receptor sign aling pathway (inferred); cognition (inferred); FOUND IN membrane (inferred); plasma membrane (inferred) | | | | Dog | 19 | GenBank Protein | gene, protein-coding, PROVISIONAL [RefSeq] |
