Taar5 (trace amine-associated receptor 5) - Rat Genome Database

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Gene: Taar5 (trace amine-associated receptor 5) Mus musculus
Analyze
Symbol: Taar5
Name: trace amine-associated receptor 5
RGD ID: 1552024
MGI Page MGI
Description: Enables trimethylamine receptor activity. Involved in adenylate cyclase-activating G protein-coupled receptor signaling pathway; cognition; and sensory perception of chemical stimulus. Predicted to be located in membrane. Predicted to be active in plasma membrane. Is expressed in Grueneberg ganglion; endolymphatic duct; nasal septum; olfactory epithelium; and utricle. Orthologous to human TAAR5 (trace amine associated receptor 5).
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: Gm227; mTaar5; taR-5; trace amine associated receptor 5; trace amine receptor 5; trimethylamine receptor
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391023,846,604 - 23,847,617 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1023,846,604 - 23,847,617 (+)EnsemblGRCm39 Ensembl
GRCm381023,970,706 - 23,971,719 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1023,970,706 - 23,971,719 (+)EnsemblGRCm38mm10GRCm38
MGSCv371023,690,512 - 23,691,525 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361023,660,122 - 23,661,135 (+)NCBIMGSCv36mm8
Celera1024,904,076 - 24,905,089 (+)NCBICelera
Cytogenetic Map10A4NCBI
cM Map1011.4NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
membrane  (RCA)
plasma membrane  (IBA,ISO,ISS)

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

References - curated
# Reference Title Reference Citation
1. Trace amine-associated receptors form structurally and functionally distinct subfamilies of novel G protein-coupled receptors. Lindemann L, etal., Genomics 2005 Mar;85(3):372-85.
2. MGDs mouse GO annotations MGD data from the GO Consortium
3. Mouse MP Annotation Import Pipeline RGD automated import pipeline
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:11459929   PMID:12477932   PMID:16602821   PMID:16878137   PMID:17556730   PMID:21267068   PMID:21677750   PMID:21873635   PMID:22545963   PMID:22837392   PMID:23177478   PMID:25616211  
PMID:25897022   PMID:27208093   PMID:30038239   PMID:32194374   PMID:33132188   PMID:34145235   PMID:34298937   PMID:34845253   PMID:36038766   PMID:37225986  


Genomics

Comparative Map Data
Taar5
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391023,846,604 - 23,847,617 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1023,846,604 - 23,847,617 (+)EnsemblGRCm39 Ensembl
GRCm381023,970,706 - 23,971,719 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1023,970,706 - 23,971,719 (+)EnsemblGRCm38mm10GRCm38
MGSCv371023,690,512 - 23,691,525 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361023,660,122 - 23,661,135 (+)NCBIMGSCv36mm8
Celera1024,904,076 - 24,905,089 (+)NCBICelera
Cytogenetic Map10A4NCBI
cM Map1011.4NCBI
TAAR5
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh386132,588,592 - 132,616,747 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl6132,588,592 - 132,589,741 (-)EnsemblGRCh38hg38GRCh38
GRCh376132,909,731 - 132,937,886 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 366132,951,505 - 132,952,518 (-)NCBINCBI36Build 36hg18NCBI36
Celera6133,656,568 - 133,657,714 (-)NCBICelera
Cytogenetic Map6q23.2NCBI
HuRef6130,484,645 - 130,485,791 (-)NCBIHuRef
CHM1_16133,173,402 - 133,174,548 (-)NCBICHM1_1
T2T-CHM13v2.06133,783,556 - 133,811,705 (-)NCBIT2T-CHM13v2.0
Taar5
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8123,289,163 - 23,290,176 (-)NCBIGRCr8
mRatBN7.2121,469,923 - 21,470,936 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl121,469,923 - 21,470,936 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx121,246,888 - 21,247,901 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0127,246,933 - 27,247,946 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0121,446,572 - 21,447,585 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0122,547,662 - 22,548,675 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl122,547,662 - 22,548,675 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0124,022,589 - 24,023,602 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4121,996,992 - 21,998,005 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1121,999,937 - 22,000,950 (-)NCBI
Celera120,213,693 - 20,214,706 (-)NCBICelera
Cytogenetic Map1p12NCBI
Taar5
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543613,152,345 - 13,153,358 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495543613,152,345 - 13,153,358 (-)NCBIChiLan1.0ChiLan1.0
LOC100976647
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v25152,570,996 - 152,572,333 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan16150,478,084 - 150,506,651 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v06130,364,744 - 130,366,076 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.16134,472,911 - 134,474,045 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl6134,472,986 - 134,473,999 (-)Ensemblpanpan1.1panPan2
TAAR5
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Dog10K_Boxer_Tasha126,626,764 - 26,627,777 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0125,550,851 - 25,551,864 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl125,550,851 - 25,551,864 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1125,596,935 - 25,597,948 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0125,495,726 - 25,496,739 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0125,758,931 - 25,759,944 (-)NCBIUU_Cfam_GSD_1.0
Taar5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404946120,842,255 - 120,843,395 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936560621,557 - 622,573 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936560621,477 - 622,605 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TAAR5
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1131,104,142 - 31,105,153 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2134,624,798 - 34,625,811 (+)NCBISscrofa10.2Sscrofa10.2susScr3
TAAR5
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11340,954,395 - 40,957,978 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1340,956,572 - 40,957,585 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604013,145,071 - 13,146,203 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Taar5
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624952748,649 - 749,660 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624952747,682 - 750,305 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Taar5
26 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:205
Count of miRNA genes:196
Interacting mature miRNAs:205
Transcripts:ENSMUST00000092659
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
11532718Sluc44f_msusceptibility to lung cancer 44f (mouse)10126289265Mouse
11532717Sluc44g_msusceptibility to lung cancer 44g (mouse)10126289265Mouse
1300881Sluc29_msusceptibility to lung cancer 29 (mouse)Not determined10126289265Mouse
12879494Facq1_mfear acquisition QTL 1 (mouse)10131279130Mouse
39128215Lwq17_mliver weight QTL 17 (mouse)101270405184079784Mouse
1302160Mbis2_mMycobacterium bovis-induced systemic lupus erythematosus 2 (mouse)Not determined102028318556031223Mouse
1300759Geot_mgeotaxia (mouse)Not determined10126289265Mouse
1558865Lith21_mlithogenic gene 21 (mouse)Not determined10852500342525126Mouse
15039341Nmrs28_mNAFLD-associated magnetic resonance shift 28 (mouse)1035100134351001Mouse
4141943W6q6_mweight 6 weeks QTL 6 (mouse)Not determined1270405184079784Mouse
1301659Arrd2_mage-related retinal degeneration 2 (mouse)Not determined102028318526890391Mouse
27226772Tibl13_mtibia length 13, 10 week (mouse)1018875748129635869Mouse
1357656Hrtq3_mheart weight QTL 3 (mouse)Not determined101270405184079784Mouse
4142380W3q11_mweight 3 weeks QTL 11 (mouse)Not determined1270405184079784Mouse
1357825Kidpq2_mkidney weight percentage QTL 2 (mouse)Not determined101270405184079784Mouse
1300997Eae15_msusceptibility to experimental allergic encephalomyelitis 15 (mouse)Not determined10440815438408276Mouse
1301003Lmblgq4_mlimb length QTL 4 (mouse)Not determined102159119268091639Mouse
1301386Sysbp1_msystolic blood pressure 1 (mouse)Not determined101010826587401095Mouse
11532725Sluc44b_msusceptibility to lung cancer 44b (mouse)10126289265Mouse
1301129Alcp15_malcohol preference locus 15 (mouse)Not determined10989026443890391Mouse
10755518Chol16_mcholesterol 16 (mouse)101891504352915043Mouse
11532724Sluc44c_msusceptibility to lung cancer 44c (mouse)10126289265Mouse
1301448Pas11_mpulmonary adenoma susceptibility 11 (mouse)Not determined10989026443890391Mouse
11532723Sluc44d_msusceptibility to lung cancer 44d (mouse)10126289265Mouse
11532722Sluc44e_msusceptibility to lung cancer 44e (mouse)10126289265Mouse
11532721Sluc44_msusceptibility to lung cancer 44 (mouse)10126289265Mouse
1558857Igan1_mIgA nephropathy 1 (mouse)Not determined101771831329704155Mouse
11532720Sluc44a_msusceptibility to lung cancer 44a (mouse)10126289265Mouse
1302092Ath11_matherosclerosis 11 (mouse)Not determined10615194558693521Mouse
1302067Scc9_mcolon tumor susceptibility 9 (mouse)Not determined1018259333125575232Mouse
1357813Ath20_matherosclerosis 20 (mouse)Not determined10328318537283334Mouse
1300790Pgia6_mproteoglycan induced arthritis 6 (mouse)Not determined10381017137810295Mouse
1302133Alcp16_malcohol preference locus 16 (mouse)Not determined10989026443890391Mouse
26884403Cvht8_mcranial vault height 8, 16 week (mouse)102287589991035862Mouse
26884394Humsd3_mhumerus midshaft diameter 3, 10 week (mouse)102237589951076096Mouse
11533917Mts2_mmammary tumor susceptibility 2 (mouse)10126289265Mouse
1558757Eae34_mexperimental allergic encephalomyelitis susceptibility 34 (mouse)Not determined1021408154114217230Mouse
13208570Bmiq9_mbody mass index QTL 9 (mouse)101287574424875898Mouse
1301796Mop2_mmorphine preference 2 (mouse)Not determined10928911929028424Mouse
13208561Wght8_mweight 8 (mouse)10495000043875996Mouse
1357740Obsty3_mobesity 3 (mouse)Not determined108235478116190980Mouse
4141956Egq7_mearly growth QTL 7 (mouse)Not determined1270405184079784Mouse
1357864Scfpq1_msubcutaneous fat pad percentage QTL 1 (mouse)Not determined101270405184079784Mouse
4142272W10q5_mweight 10 weeks QTL 5 (mouse)Not determined1270405184079784Mouse

Markers in Region
Taar5  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381023,970,781 - 23,971,587UniSTSGRCm38
MGSCv371023,690,587 - 23,691,393UniSTSGRCm37
Celera1024,904,151 - 24,904,957UniSTS
Cytogenetic Map10A4UniSTS
cM Map10 UniSTS


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSMUST00000092659   ⟹   ENSMUSP00000090329
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1023,846,604 - 23,847,617 (+)Ensembl
GRCm38.p6 Ensembl1023,970,706 - 23,971,719 (+)Ensembl
RefSeq Acc Id: NM_001009574   ⟹   NP_001009574
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391023,846,604 - 23,847,617 (+)NCBI
GRCm381023,970,706 - 23,971,719 (+)ENTREZGENE
MGSCv371023,690,512 - 23,691,525 (+)RGD
Celera1024,904,076 - 24,905,089 (+)RGD
cM Map10 ENTREZGENE
Sequence:
Protein Sequences
Protein RefSeqs NP_001009574 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAI39189 (Get FASTA)   NCBI Sequence Viewer  
  AAI39192 (Get FASTA)   NCBI Sequence Viewer  
  AAV70139 (Get FASTA)   NCBI Sequence Viewer  
  ACP18688 (Get FASTA)   NCBI Sequence Viewer  
  EDL04775 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSMUSP00000090329
  ENSMUSP00000090329.3
GenBank Protein Q5QD14 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_001009574   ⟸   NM_001009574
- UniProtKB: Q5QD14 (UniProtKB/Swiss-Prot),   B2RTA0 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSMUSP00000090329   ⟸   ENSMUST00000092659
Protein Domains
G-protein coupled receptors family 1 profile   G-protein coupled receptors family 2 profile

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q5QD14-F1-model_v2 AlphaFold Q5QD14 1-337 view protein structure

Promoters
RGD ID:8671666
Promoter ID:EPDNEW_M13861
Type:single initiation site
Name:Taar5_1
Description:Mus musculus trace amine-associated receptor 5 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381023,970,717 - 23,970,777EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:2685073 AgrOrtholog
Ensembl Genes ENSMUSG00000069706 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000092659 ENTREZGENE
  ENSMUST00000092659.4 UniProtKB/Swiss-Prot
Gene3D-CATH Rhodopsin 7-helix transmembrane proteins UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro GPCR_2-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GPCR_Rhodpsn UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GPCR_Rhodpsn_7TM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TAAR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TAAR_fam UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:215854 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:2685073 ENTREZGENE
NCBI Gene 215854 ENTREZGENE
PANTHER HISTAMINE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TRACE AMINE-ASSOCIATED RECEPTOR 5 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam 7tm_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Taar5 PhenoGen
PRINTS GPCRRHODOPSN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TRACEAMINER UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F1_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F1_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F2_4 UniProtKB/TrEMBL
SMART 7TM_GPCR_Srsx UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP Family A G protein-coupled receptor-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt B2RTA0 ENTREZGENE, UniProtKB/TrEMBL
  Q5QD14 ENTREZGENE, UniProtKB/Swiss-Prot