TAAR5 (trace amine associated receptor 5)

Gene: TAAR5 (trace amine associated receptor 5) Canis lupus familiaris

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Symbol:

TAAR5

Name:

trace amine associated receptor 5

RGD ID:

12075132

Description:

ENCODES a protein that exhibits G protein-coupled receptor activity (inferred); trace-amine receptor activity (inferred); trimethylamine receptor activity (inferred); INVOLVED IN cell surface receptor signaling pathway (inferred); G protein-coupled receptor signaling pathway (inferred); sensory perception of chemical stimulus (inferred); ASSOCIATED WITH genetic disease (ortholog); FOUND IN membrane (inferred); plasma membrane (inferred)

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

trace amine-associated receptor 5

RGD Orthologs

Alliance Genes

More Info

more info ...

Latest Assembly:

CanFam3.1 - Dog CanFam3.1 Assembly

Position:

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Dog10K_Boxer_Tasha	1	26,626,764 - 26,627,777 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	1	25,550,851 - 25,551,864 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	1	25,550,851 - 25,551,864 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	1	25,596,935 - 25,597,948 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	1	25,495,726 - 25,496,739 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	1	25,758,931 - 25,759,944 (-)	NCBI		UU_Cfam_GSD_1.0

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

genetic disease (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cell surface receptor signaling pathway (IEA)

G protein-coupled receptor signaling pathway (IEA)

sensory perception of chemical stimulus (IEA)

Cellular Component

membrane (IEA)

plasma membrane (IEA)

Molecular Function

G protein-coupled receptor activity (IEA)

trace-amine receptor activity (IBA,IEA)

trimethylamine receptor activity (IEA)

References

Additional References at PubMed

PMID:20559446	PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

TAAR5
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Dog10K_Boxer_Tasha	1	26,626,764 - 26,627,777 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	1	25,550,851 - 25,551,864 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	1	25,550,851 - 25,551,864 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	1	25,596,935 - 25,597,948 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	1	25,495,726 - 25,496,739 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	1	25,758,931 - 25,759,944 (-)	NCBI		UU_Cfam_GSD_1.0

TAAR5
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	6	132,588,592 - 132,616,747 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	6	132,588,592 - 132,589,741 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	6	132,909,731 - 132,937,886 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	6	132,951,505 - 132,952,518 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	6	133,656,568 - 133,657,714 (-)	NCBI		Celera
Cytogenetic Map	6	q23.2	NCBI
HuRef	6	130,484,645 - 130,485,791 (-)	NCBI		HuRef
CHM1_1	6	133,173,402 - 133,174,548 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	6	133,783,556 - 133,811,705 (-)	NCBI		T2T-CHM13v2.0

Taar5
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	10	23,846,604 - 23,847,617 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	10	23,846,604 - 23,847,617 (+)	Ensembl		GRCm39 Ensembl
GRCm38	10	23,970,706 - 23,971,719 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	10	23,970,706 - 23,971,719 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	10	23,690,512 - 23,691,525 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	10	23,660,122 - 23,661,135 (+)	NCBI		MGSCv36	mm8
Celera	10	24,904,076 - 24,905,089 (+)	NCBI		Celera
Cytogenetic Map	10	A4	NCBI
cM Map	10	11.4	NCBI

Taar5
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	23,289,163 - 23,290,176 (-)	NCBI		GRCr8
mRatBN7.2	1	21,469,923 - 21,470,936 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	21,469,923 - 21,470,936 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	1	21,246,888 - 21,247,901 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	27,246,933 - 27,247,946 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	21,446,572 - 21,447,585 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	22,547,662 - 22,548,675 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	22,547,662 - 22,548,675 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	1	24,022,589 - 24,023,602 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	1	21,996,992 - 21,998,005 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	1	21,999,937 - 22,000,950 (-)	NCBI
Celera	1	20,213,693 - 20,214,706 (-)	NCBI		Celera
Cytogenetic Map	1	p12	NCBI

Taar5
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955436	13,152,345 - 13,153,358 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955436	13,152,345 - 13,153,358 (-)	NCBI	ChiLan1.0	ChiLan1.0

LOC100976647
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	5	152,570,996 - 152,572,333 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	6	150,478,084 - 150,506,651 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	6	130,364,744 - 130,366,076 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	6	134,472,911 - 134,474,045 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	6	134,472,986 - 134,473,999 (-)	Ensembl	panpan1.1		panPan2

Taar5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404946	120,842,255 - 120,843,395 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936560	621,557 - 622,573 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936560	621,477 - 622,605 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

TAAR5
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1	1	31,104,142 - 31,105,153 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	1	34,624,798 - 34,625,811 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

TAAR5
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	13	40,954,395 - 40,957,978 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	13	40,956,572 - 40,957,585 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666040	13,145,071 - 13,146,203 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Taar5
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624952	748,649 - 749,660 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624952	747,682 - 750,305 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	hemolymphoid system	reproductive system
High
Medium
Low
Below cutoff	1	1	1

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001197146	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AAEX04000001	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FJ372543	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAHUQ010000004	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAQRD010000001	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAUVH010000354	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	REHQ01000001	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSCAFT00845008358 ⟹ ENSCAFP00845006577

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	1	25,550,851 - 25,551,864 (-)	Ensembl

RefSeq Acc Id:

NM_001197146 ⟹ NP_001184075

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
Dog10K_Boxer_Tasha	1	26,626,764 - 26,627,777 (-)	NCBI
ROS_Cfam_1.0	1	25,550,851 - 25,551,864 (-)	NCBI
UMICH_Zoey_3.1	1	25,596,935 - 25,597,948 (-)	NCBI
UNSW_CanFamBas_1.0	1	25,495,726 - 25,496,739 (-)	NCBI
UU_Cfam_GSD_1.0	1	25,758,931 - 25,759,944 (-)	NCBI

Sequence:

show sequence

ATGGACACTGTCCTCAGCCAAGGTTCTGAAGAACGCCCCACCACTTTCTGCTACCAGGTGAATG
GGTCTTGCCCCAGGACAGTCCATCCTCTGGACATCCAGTTGGCCATCTACATGGCCTGTGCAGT
AGGCATGCTGATTACAGTCCTGGGAAATTTGTTTGTGGTGTTTGCTGTGTCCTACTTCAAAGTG
CTTCACACTCCCACCAACTTCTTGCTGCTTTCCCTGGCCCTGGCTGACATGTTTCTGGGTCTGC
TGGTGCTGCCCCTCAGTACCATTCGCTCAGTGGAGAGCTGCTGGTTCTTTGGAGACTTCCTCTG
CCGCCTGCATACCTACCTGGACACCCTCTTCTGTCTCACCTCCATCTTTCATCTCTGTTTCATT
TCCATTGACCGCCACTGTGCCATCTGTGAGCCCCTGATCTATCCTTCCAAGTTCACAGTCAGGG
TGGCTGTCAGGTACATCCTGGCAGGGTGGGGGATTCCAGCGGCTTACACTGCCTTCTTCCTCTA
CACAGATGTGGTAGAAAATGGGCTCAGTCAGTGGCTGGAAGAGATGCCTTGTGTGGGCAGTTGC
CAGCTGCTATTCAATAAGTTTTGGGGCTGGTTAAATTTTCCTATGTTCTTTTTCCCCTGCCTCA
TCATGATCAGCTTGTATGTGAAGATTTTTGTGGTTGCTACTAAGCAGGCTCAGCAGATCAGCAC
CTTGAGCAAAAACCTGGCTGGGGCTGCCAAACGTGAAAGAAAAGCTGCCAAGACCCTGGGCATC
GCTGTGGGCATATACCTCTTGTGCTGGCTTCCCTTCACCATTGACACTCTGGTTGACAGCCTCC
TTAACTTCATCACACCACCACTGGTTTTTGACATCTTTATCTGGTTTGCTTATTTCAACTCAGC
CTGCAACCCTATCATCTATGTCTTTTCCTACCGGTGGTTCAGAAAGGCACTGAAACTCTGCCTG
AGTCAGGAGATCTTCTCACCTCGGACACCCACTATTGATTTGTACCAAGAATGA

hide sequence

Protein Sequences


Protein RefSeqs	NP_001184075	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	ACP18678	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCAFP00000000267.3
	ENSCAFP00040022025.1
	ENSCAFP00845006577
	ENSCAFP00845006577.1

RefSeq Acc Id:

NP_001184075 ⟸ NM_001197146

- UniProtKB:

D8KZR7 (UniProtKB/TrEMBL), H9GW46 (UniProtKB/TrEMBL), A0A8C0LC51 (UniProtKB/TrEMBL), A0A8C0SKC5 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MDTVLSQGSEERPTTFCYQVNGSCPRTVHPLDIQLAIYMACAVGMLITVLGNLFVVFAVSYFKV
LHTPTNFLLLSLALADMFLGLLVLPLSTIRSVESCWFFGDFLCRLHTYLDTLFCLTSIFHLCFI
SIDRHCAICEPLIYPSKFTVRVAVRYILAGWGIPAAYTAFFLYTDVVENGLSQWLEEMPCVGSC
QLLFNKFWGWLNFPMFFFPCLIMISLYVKIFVVATKQAQQISTLSKNLAGAAKRERKAAKTLGI
AVGIYLLCWLPFTIDTLVDSLLNFITPPLVFDIFIWFAYFNSACNPIIYVFSYRWFRKALKLCL
SQEIFSPRTPTIDLYQE

hide sequence

RefSeq Acc Id:

ENSCAFP00845006577 ⟸ ENSCAFT00845008358

Protein Domains

G-protein coupled receptors family 1 profile G-protein coupled receptors family 2 profile

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCAFG00000000187	UniProtKB/TrEMBL
	ENSCAFG00040013729	UniProtKB/TrEMBL
	ENSCAFG00845004676	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCAFT00000000296.4	UniProtKB/TrEMBL
	ENSCAFT00040025339.1	UniProtKB/TrEMBL
	ENSCAFT00845008358	ENTREZGENE
	ENSCAFT00845008358.1	UniProtKB/TrEMBL
Gene3D-CATH	Rhodopsin 7-helix transmembrane proteins	UniProtKB/TrEMBL
InterPro	GPCR_2-like	UniProtKB/TrEMBL
	GPCR_Rhodpsn	UniProtKB/TrEMBL
	GPCR_Rhodpsn_7TM	UniProtKB/TrEMBL
	TAAR_fam	UniProtKB/TrEMBL
KEGG Report	cfa:483989	UniProtKB/TrEMBL
NCBI Gene	TAAR5	ENTREZGENE
PANTHER	HISTAMINE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR	UniProtKB/TrEMBL
	TRACE AMINE-ASSOCIATED RECEPTOR 5	UniProtKB/TrEMBL
Pfam	7tm_1	UniProtKB/TrEMBL
PRINTS	GPCRRHODOPSN	UniProtKB/TrEMBL
	TRACEAMINER	UniProtKB/TrEMBL
PROSITE	G_PROTEIN_RECEP_F1_1	UniProtKB/TrEMBL
	G_PROTEIN_RECEP_F1_2	UniProtKB/TrEMBL
	G_PROTEIN_RECEP_F2_4	UniProtKB/TrEMBL
SMART	7TM_GPCR_Srsx	UniProtKB/TrEMBL
Superfamily-SCOP	Family A G protein-coupled receptor-like	UniProtKB/TrEMBL
UniProt	A0A8C0LC51	ENTREZGENE
	A0A8C0SKC5	ENTREZGENE, UniProtKB/TrEMBL
	D8KZR7	ENTREZGENE, UniProtKB/TrEMBL
	H9GW46	ENTREZGENE
UniProt Secondary	H9GW46	UniProtKB/TrEMBL
VGNC ID	VGNC:47059	ENTREZGENE

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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