Per3 (period circadian regulator 3) - Rat Genome Database

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Gene: Per3 (period circadian regulator 3) Rattus norvegicus
Analyze
Symbol: Per3
Name: period circadian regulator 3
RGD ID: 621581
Description: Predicted to enable enzyme binding activity; transcription cis-regulatory region binding activity; and transcription corepressor binding activity. Predicted to be involved in several processes, including entrainment of circadian clock by photoperiod; protein stabilization; and regulation of gene expression. Predicted to act upstream of or within circadian rhythm. Predicted to be active in cytoplasm and nucleus. Biomarker of alcohol use disorder. Human ortholog(s) of this gene implicated in advanced sleep phase syndrome; advanced sleep phase syndrome 3; and bipolar disorder. Orthologous to human PER3 (period circadian regulator 3); INTERACTS WITH (+)-schisandrin B; 1-naphthyl isothiocyanate; 17beta-estradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: circadian clock protein PERIOD 3; period circadian clock 3; period circadian protein homolog 3; period homolog 3; period homolog 3 (Drosophila); period3; rper3
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85166,740,914 - 166,778,243 (-)NCBIGRCr8
mRatBN7.25161,460,228 - 161,495,404 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5161,459,533 - 161,495,607 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5164,177,009 - 164,211,658 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05165,993,418 - 166,028,287 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05165,955,653 - 165,990,302 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.05168,088,126 - 168,123,482 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5168,086,998 - 168,123,395 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05171,665,221 - 171,700,529 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45168,152,693 - 168,187,442 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.15168,163,026 - 168,197,630 (-)NCBI
Celera5159,712,426 - 159,747,156 (-)NCBICelera
Cytogenetic Map5q36NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model



  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Per3Ratadvanced sleep phase syndrome  ISOPER3 (Homo sapiens)1358557DNA:missense mutations:cds:multiple (human)RGD 
Per3Ratalcohol use disorder  IEP 407572515mRNA:altered expression:suprachiasmatic nucleusRGD 
Per3Ratbipolar disorder sexual_dimorphismISOPER3 (Homo sapiens)405866353associated with Alcohol-Related Disorders and DNA:SNP::(rs228642) (Human)RGD 
Per3RatCOVID-19  ISOPER3 (Homo sapiens)9068941mRNA:decreased expression:peripheral blood mononuclear cell (human)RGDPMID:32228226 and REF_RGD_ID:28912744
Per3RatPrenatal Exposure Delayed Effects  IEP 405866367associated with alcohol use disorder more ...RGD 
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Per3Ratadvanced sleep phase syndrome 3  ISOPER3 (Homo sapiens)8554872ClinVar more ...ClinVarPMID:25741868 more ...
Per3Ratchromosome 1p36 deletion syndrome  ISOPER3 (Homo sapiens)8554872ClinVar Annotator: match by term: Chromosome 1p36 deletion syndromeClinVar 
Per3RatNeurodevelopmental Disorders  ISOPER3 (Homo sapiens)8554872ClinVar Annotator: match by term: Neurodevelopmental disorderClinVarPMID:25741868
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Per3Ratadvanced sleep phase syndrome 1  ISOPER3 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTD 
Per3RatBreast Neoplasms  ISOPER3 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:20625127
Per3Ratchronic myeloid leukemia  ISOPER3 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:16999817
Per3Ratwithdrawal disorder  ISOPER3 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:20738730
Object Symbol
Species
Term
Qualifier
Evidence
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Reference
Notes
Source
Original Reference(s)
Per3Ratadvanced sleep phase syndrome 3  ISOPER3 (Homo sapiens)7240710 OMIM 

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Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Per3Rat(+)-schisandrin B multiple interactionsEXP 6480464schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of PER3 mRNA]CTDPMID:31150632
Per3Rat(1->4)-beta-D-glucan multiple interactionsISOPer3 (Mus musculus)6480464[perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of PER3 mRNACTDPMID:36331819
Per3Rat1,2-dimethylhydrazine decreases expressionISOPer3 (Mus musculus)64804641 and 2-Dimethylhydrazine results in decreased expression of PER3 mRNACTDPMID:22206623
Per3Rat1-naphthyl isothiocyanate increases expressionEXP 64804641-Naphthylisothiocyanate results in increased expression of PER3 mRNACTDPMID:30723492
Per3Rat17beta-estradiol affects expressionEXP 6480464Estradiol affects the expression of PER3 mRNACTDPMID:32145629
Per3Rat17beta-estradiol decreases expressionISOPer3 (Mus musculus)6480464Estradiol results in decreased expression of PER3 mRNACTDPMID:39298647
Per3Rat2,2',4,4',5,5'-hexachlorobiphenyl multiple interactionsISOPer3 (Mus musculus)6480464[Tetrachlorodibenzodioxin co-treated with 2 more ...CTDPMID:28433925
Per3Rat2,3,7,8-tetrachlorodibenzodioxine affects expressionISOPer3 (Mus musculus)6480464Tetrachlorodibenzodioxin affects the expression of PER3 mRNACTDPMID:21570461 and PMID:28922406
Per3Rat2,3,7,8-tetrachlorodibenzodioxine increases expressionEXP 6480464Tetrachlorodibenzodioxin results in increased expression of PER3 mRNACTDPMID:34747641
Per3Rat2,3,7,8-tetrachlorodibenzodioxine multiple interactionsISOPer3 (Mus musculus)6480464[Tetrachlorodibenzodioxin co-treated with 2 more ...CTDPMID:28433925
Per3Rat2,3,7,8-tetrachlorodibenzodioxine decreases expressionEXP 6480464Tetrachlorodibenzodioxin results in decreased expression of PER3 mRNACTDPMID:21215274 and PMID:22808131
Per3Rat2,4-D multiple interactionsISOPer3 (Mus musculus)6480464[lard co-treated with Cholesterol more ...CTDPMID:37567420
Per3Rat3,3',4,4',5-pentachlorobiphenyl increases expressionEXP 64804643 more ...CTDPMID:23196670 and PMID:32119087
Per3Rat3,3',4,4'-tetrachlorobiphenyl multiple interactionsISOPer3 (Mus musculus)64804643 more ...CTDPMID:19467301
Per3Rat3,4-methylenedioxymethamphetamine increases expressionISOPer3 (Mus musculus)6480464N-Methyl-3 and 4-methylenedioxyamphetamine results in increased expression of PER3 mRNACTDPMID:26251327
Per3Rat3,4-methylenedioxymethamphetamine increases methylationISOPer3 (Mus musculus)6480464N-Methyl-3 and 4-methylenedioxyamphetamine results in increased methylation of PER3 promoterCTDPMID:26251327
Per3Rat3,4-methylenedioxymethamphetamine decreases expressionISOPer3 (Mus musculus)6480464N-Methyl-3 and 4-methylenedioxyamphetamine results in decreased expression of PER3 mRNACTDPMID:26251327
Per3Rat4,4'-sulfonyldiphenol decreases expressionISOPer3 (Mus musculus)6480464bisphenol S results in decreased expression of PER3 mRNACTDPMID:33297965 and PMID:39298647
Per3Rat4-hydroxyphenyl retinamide decreases expressionISOPer3 (Mus musculus)6480464Fenretinide results in decreased expression of PER3 mRNACTDPMID:28973697
Per3Rat6-propyl-2-thiouracil decreases expressionEXP 6480464Propylthiouracil results in decreased expression of PER3 mRNACTDPMID:24780913

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Biological Process
1 to 14 of 14 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Per3Ratcircadian regulation of gene expression involved_inIBAFB:FBgn0003068 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Per3Ratcircadian rhythm involved_inIEAARBA:ARBA000279011600115GO_REF:0000117UniProtGO_REF:0000117
Per3Ratcircadian rhythm acts_upstream_of_or_withinISOPer3 (Mus musculus)1624291 PMID:12843397RGDPMID:12843397
Per3Ratentrainment of circadian clock by photoperiod involved_inIBAFB:FBgn0003068 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Per3Ratnegative regulation of transcription by RNA polymerase II involved_inISSUniProtKB:P566451600115GO_REF:0000024UniProtGO_REF:0000024
Per3Ratnegative regulation of transcription by RNA polymerase II acts_upstream_of_or_withinISOPer3 (Mus musculus)1624291 PMID:9989497RGDPMID:9989497
Per3Ratnegative regulation of transcription by RNA polymerase II involved_inIBAFB:FBgn0003068 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Per3Ratnegative regulation of transcription by RNA polymerase II involved_inISOPER3 (Homo sapiens)1624291 PMID:26903630RGDPMID:26903630
Per3Ratprotein stabilization involved_inISSUniProtKB:P566451600115GO_REF:0000024UniProtGO_REF:0000024
Per3Ratprotein stabilization involved_inISOPER3 (Homo sapiens)1624291 PMID:26903630RGDPMID:26903630
Per3Ratregulation of circadian sleep/wake cycle, sleep involved_inISSUniProtKB:P566451600115GO_REF:0000024UniProtGO_REF:0000024
Per3Ratregulation of circadian sleep/wake cycle, sleep involved_inISOPer3 (Mus musculus)1624291 PMID:21957163RGDPMID:21957163
Per3Ratregulation of circadian sleep/wake cycle, sleep involved_inISOPER3 (Homo sapiens)1624291 PMID:17346965 more ...RGDPMID:17346965 more ...
Per3Ratrhythmic process involved_inIEAUniProtKB-KW:KW-00901600115GO_REF:0000043UniProtGO_REF:0000043
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Cellular Component
1 to 10 of 10 rows

  
Object Symbol
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Term
Qualifier
Evidence
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Reference
Notes
Source
Original Reference(s)
Per3Ratcytoplasm located_inISSUniProtKB:P566451600115GO_REF:0000024UniProtGO_REF:0000024
Per3Ratcytoplasm located_inIEAUniProtKB-KW:KW-09631600115GO_REF:0000043UniProtGO_REF:0000043
Per3Ratcytoplasm is_active_inIBAFB:FBgn0003068 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Per3Ratcytoplasm located_inISOPER3 (Homo sapiens)1624291 PMID:26903630RGDPMID:26903630
Per3Ratcytoplasm located_inIEAUniProtKB-SubCell:SL-00861600115GO_REF:0000044UniProtGO_REF:0000044
Per3Ratnucleus located_inIEAUniProtKB-SubCell:SL-01911600115GO_REF:0000044UniProtGO_REF:0000044
Per3Ratnucleus located_inIEAUniProtKB-KW:KW-05391600115GO_REF:0000043UniProtGO_REF:0000043
Per3Ratnucleus is_active_inIBAFB:FBgn0003068 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Per3Ratnucleus located_inISSUniProtKB:P566451600115GO_REF:0000024UniProtGO_REF:0000024
Per3Ratnucleus located_inISOPER3 (Homo sapiens)1624291 PMID:26903630RGDPMID:26903630
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Molecular Function

  


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#
Reference Title
Reference Citation
1. Clock genes polymorphisms in male bipolar patients with comorbid alcohol abuse. Banach E, etal., J Affect Disord. 2018 Dec 1;241:142-146. doi: 10.1016/j.jad.2018.07.080. Epub 2018 Jul 31.
2. Chronic ethanol consumption impairs the circadian rhythm of pro-opiomelanocortin and period genes mRNA expression in the hypothalamus of the male rat. Chen CP, etal., J Neurochem. 2004 Mar;88(6):1547-54. doi: 10.1046/j.1471-4159.2003.02300.x.
3. Prenatal ethanol exposure alters the expression of period genes governing the circadian function of beta-endorphin neurons in the hypothalamus. Chen CP, etal., J Neurochem. 2006 May;97(4):1026-33. doi: 10.1111/j.1471-4159.2006.03839.x.
4. Association of structural polymorphisms in the human period3 gene with delayed sleep phase syndrome. Ebisawa T, etal., EMBO Rep 2001 Apr;2(4):342-6.
5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
6. Implications of circadian gene expression in kidney, liver and the effects of fasting on pharmacogenomic studies. Kita Y, etal., Pharmacogenetics 2002 Jan;12(1):55-65.
7. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
8. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
9. GOA pipeline RGD automated data pipeline
10. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
11. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
12. Effect of fluoxetine and cocaine on the expression of clock genes in the mouse hippocampus and striatum. Uz T, etal., Neuroscience. 2005;134(4):1309-16. doi: 10.1016/j.neuroscience.2005.05.003.
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PMID:9989497   PMID:12843397   PMID:14564007   PMID:15917222   PMID:16267386   PMID:17346965   PMID:19716732   PMID:20738730   PMID:21957163   PMID:24439663   PMID:24577121   PMID:26903630  



Per3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85166,740,914 - 166,778,243 (-)NCBIGRCr8
mRatBN7.25161,460,228 - 161,495,404 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5161,459,533 - 161,495,607 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5164,177,009 - 164,211,658 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05165,993,418 - 166,028,287 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05165,955,653 - 165,990,302 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.05168,088,126 - 168,123,482 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5168,086,998 - 168,123,395 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05171,665,221 - 171,700,529 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45168,152,693 - 168,187,442 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.15168,163,026 - 168,197,630 (-)NCBI
Celera5159,712,426 - 159,747,156 (-)NCBICelera
Cytogenetic Map5q36NCBI
PER3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3817,784,291 - 7,845,177 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl17,784,291 - 7,845,177 (+)EnsemblGRCh38hg38GRCh38
GRCh3717,844,351 - 7,905,237 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3617,767,350 - 7,827,824 (+)NCBINCBI36Build 36hg18NCBI36
Build 3417,779,028 - 7,839,503NCBI
Celera16,952,489 - 7,012,918 (+)NCBICelera
Cytogenetic Map1p36.23NCBI
HuRef16,993,003 - 7,053,532 (+)NCBIHuRef
CHM1_117,832,500 - 7,892,974 (+)NCBICHM1_1
T2T-CHM13v2.017,315,337 - 7,376,224 (+)NCBIT2T-CHM13v2.0
Per3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394151,081,475 - 151,129,167 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4151,088,109 - 151,129,122 (-)EnsemblGRCm39 Ensembl
GRCm384150,997,018 - 151,044,707 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4151,003,652 - 151,044,665 (-)EnsemblGRCm38mm10GRCm38
MGSCv374150,377,764 - 150,418,731 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv364149,848,512 - 149,888,389 (-)NCBIMGSCv36mm8
Celera4153,279,480 - 153,320,397 (-)NCBICelera
Cytogenetic Map4E2NCBI
cM Map481.53NCBI
Per3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554865,059,773 - 5,101,637 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554865,058,602 - 5,101,480 (-)NCBIChiLan1.0ChiLan1.0
PER3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21220,381,214 - 220,442,021 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11219,022,337 - 219,083,038 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v016,547,667 - 6,607,905 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.117,795,549 - 7,855,922 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl17,795,552 - 7,855,922 (+)Ensemblpanpan1.1panPan2
PER3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1561,445,580 - 61,499,393 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl561,445,461 - 61,498,499 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha561,454,281 - 61,508,079 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0561,662,394 - 61,716,172 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl561,662,356 - 61,716,152 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1561,661,665 - 61,715,387 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0561,526,094 - 61,579,868 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0561,929,781 - 61,983,527 (+)NCBIUU_Cfam_GSD_1.0
Per3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505831,805,406 - 31,853,491 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366232,290,614 - 2,336,634 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366232,291,211 - 2,362,693 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PER3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1668,487,634 - 68,548,718 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
PER3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.120123,912,773 - 123,970,440 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl20123,912,208 - 123,970,549 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605427,947,725 - 28,005,720 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Per3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248183,967,333 - 4,007,739 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248183,959,639 - 4,007,739 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

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Variants in Per3
225 total Variants

Predicted Target Of
Summary Value
Count of predictions:157
Count of miRNA genes:128
Interacting mature miRNAs:139
Transcripts:ENSRNOT00000024932
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 20 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
10053720Scort26Serum corticosterone level QTL 262.060.0147blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)5124965598166875058Rat
631272Lanf1Left ventricular atrial natriuretic factor QTL 112heart left ventricle natriuretic peptide A amount (VT:0010596)heart left ventricle natriuretic peptide A level (CMO:0002165)5151113452166875058Rat
1576314Eutr1Estrogen induced uterine response QTL 1uterus integrity trait (VT:0010575)pyometritis severity score (CMO:0002009)52138965166875058Rat
631562Apr2Acute phase response QTL 23.7blood murinoglobulin 1 amount (VT:0010597)plasma murinoglobulin 1 level (CMO:0001931)5135927956166875058Rat
634349Bp139Blood pressure QTL 1390.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5128924607166875058Rat
61444Strs2Sensitivity to stroke QTL 24.7cerebrum integrity trait (VT:0010549)post-insult time to onset of cerebrovascular lesion (CMO:0002343)5135929696166875058Rat
724525Bp147Blood pressure QTL 1474.30.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5126424772166875058Rat
1549904Neuinf1Neuroinflammation QTL 130nervous system integrity trait (VT:0010566)blood T lymphocyte count (CMO:0000110)5154828214166875058Rat
738018Anxrr4Anxiety related response QTL 45.1exploratory behavior trait (VT:0010471)percentage of entries into a discrete space in an experimental apparatus (CMO:0000961)5130130159166875058Rat
8552908Pigfal4Plasma insulin-like growth factor 1 level QTL 46.6blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)5128506074166875058Rat

1 to 10 of 20 rows
D5Mco10  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr85166,764,253 - 166,764,498 (+)Marker Load Pipeline
mRatBN7.25161,481,433 - 161,481,680 (+)MAPPERmRatBN7.2
Rnor_6.05168,109,415 - 168,109,659NCBIRnor6.0
Rnor_5.05171,686,510 - 171,686,754UniSTSRnor5.0
RGSC_v3.45168,173,895 - 168,174,140RGDRGSC3.4
RGSC_v3.45168,173,896 - 168,174,140UniSTSRGSC3.4
RGSC_v3.15168,184,083 - 168,184,328RGD
Celera5159,733,610 - 159,733,854UniSTS
Cytogenetic Map5q36UniSTS
BF419445  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.25161,476,220 - 161,476,346 (+)MAPPERmRatBN7.2
Rnor_6.05168,104,117 - 168,104,242NCBIRnor6.0
Rnor_5.05171,681,212 - 171,681,337UniSTSRnor5.0
RGSC_v3.45168,168,684 - 168,168,809UniSTSRGSC3.4
Celera5159,728,417 - 159,728,542UniSTS
RH 3.4 Map51128.4UniSTS
Cytogenetic Map5q36UniSTS




alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31



Ensembl Acc Id: ENSRNOT00000024932   ⟹   ENSRNOP00000024932
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl5161,460,228 - 161,495,607 (-)Ensembl
Rnor_6.0 Ensembl5168,086,998 - 168,123,395 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000092747   ⟹   ENSRNOP00000076026
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl5161,460,374 - 161,495,607 (-)Ensembl
Rnor_6.0 Ensembl5168,088,272 - 168,123,030 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000092840
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl5168,119,561 - 168,123,030 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000092912
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl5168,109,659 - 168,110,285 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000092923
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl5168,121,316 - 168,123,021 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000093063   ⟹   ENSRNOP00000075932
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl5168,112,376 - 168,120,179 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000093100
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl5168,121,998 - 168,122,977 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000093114
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl5168,121,329 - 168,121,640 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000108999   ⟹   ENSRNOP00000094435
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl5161,459,533 - 161,495,295 (-)Ensembl
RefSeq Acc Id: NM_023978   ⟹   NP_076468
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85166,743,050 - 166,777,800 (-)NCBI
mRatBN7.25161,460,228 - 161,494,982 (-)NCBI
Rnor_6.05168,088,126 - 168,123,030 (-)NCBI
Rnor_5.05171,665,221 - 171,700,529 (-)NCBI
RGSC_v3.45168,152,693 - 168,187,442 (-)RGD
Celera5159,712,426 - 159,747,156 (-)RGD
Sequence:
RefSeq Acc Id: XM_006239504   ⟹   XP_006239566
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85166,740,914 - 166,778,243 (-)NCBI
mRatBN7.25161,460,244 - 161,495,402 (-)NCBI
Rnor_6.05168,088,190 - 168,123,482 (-)NCBI
Rnor_5.05171,665,221 - 171,700,529 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006239505   ⟹   XP_006239567
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85166,740,914 - 166,778,243 (-)NCBI
mRatBN7.25161,460,244 - 161,495,402 (-)NCBI
Rnor_6.05168,088,190 - 168,123,482 (-)NCBI
Rnor_5.05171,665,221 - 171,700,529 (-)NCBI
Sequence:
RefSeq Acc Id: XM_063288459   ⟹   XP_063144529
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85166,740,914 - 166,774,204 (-)NCBI
RefSeq Acc Id: NP_076468   ⟸   NM_023978
- UniProtKB: G3V8D9 (UniProtKB/TrEMBL),   A6IUE8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006239567   ⟸   XM_006239505
- Peptide Label: isoform X2
- UniProtKB: G3V8D9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006239566   ⟸   XM_006239504
- Peptide Label: isoform X1
- UniProtKB: G3V8D9 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000076026   ⟸   ENSRNOT00000092747
Ensembl Acc Id: ENSRNOP00000024932   ⟸   ENSRNOT00000024932
PAC   PAS

Name Modeler Protein Id AA Range Protein Structure
AF-Q8CJE2-F1-model_v2 AlphaFold Q8CJE2 1-1119 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

RGD ID:13694287
Promoter ID:EPDNEW_R4812
Type:initiation region
Name:Per3_1
Description:period circadian regulator 3
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.05168,123,419 - 168,123,479EPDNEW


1 to 31 of 31 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-39044 BioCyc
Ensembl Genes ENSRNOG00000018413 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000024932 ENTREZGENE
  ENSRNOT00000024932.6 UniProtKB/TrEMBL
  ENSRNOT00000092747.2 UniProtKB/TrEMBL
  ENSRNOT00000108999.1 UniProtKB/TrEMBL
Gene3D-CATH PAS domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro PAS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PAS-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PAS_fold_3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Per1-3_PAS-A UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Period_circadian-like_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Period_circadian_regulator UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:78962 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene 78962 ENTREZGENE
PANTHER PERIOD CIRCADIAN PROTEIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR11269:SF13 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam PAS_3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Per3-like_PAS-A UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Period_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Per3 PhenoGen
PROSITE PAS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000018413 RatGTEx
SMART PAS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF55785 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A1B0GWU7_RAT UniProtKB/TrEMBL
  A0A8I6AN92_RAT UniProtKB/TrEMBL
  A6IUE8 ENTREZGENE, UniProtKB/TrEMBL
  A6IUF0_RAT UniProtKB/TrEMBL
  G3V8D9 ENTREZGENE, UniProtKB/TrEMBL
  PER3_RAT UniProtKB/Swiss-Prot, ENTREZGENE
1 to 31 of 31 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2017-10-09 Per3  period circadian regulator 3  Per3  period circadian clock 3  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2013-01-02 Per3  period circadian clock 3  Per3  period homolog 3 (Drosophila)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2004-09-10 Per3  period homolog 3 (Drosophila)      Symbol and Name status set to approved 1299863 APPROVED
2002-08-07 Per3  period homolog 3 (Drosophila)      Symbol and Name status set to provisional 70820 PROVISIONAL