PER3 (period circadian regulator 3) - Rat Genome Database

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Gene: PER3 (period circadian regulator 3) Sus scrofa
Analyze
Symbol: PER3
Name: period circadian regulator 3
RGD ID: 14179652
Description: ENCODES a protein that exhibits kinase binding (ortholog); ubiquitin protein ligase binding (ortholog); INVOLVED IN circadian rhythm (ortholog); negative regulation of transcription by RNA polymerase II (ortholog); protein stabilization (ortholog); ASSOCIATED WITH advanced sleep phase syndrome (ortholog); advanced sleep phase syndrome 1 (ortholog); advanced sleep phase syndrome 3 (ortholog); FOUND IN cytoplasm (inferred); nucleus (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: period circadian clock 3; period circadian protein homolog 3; period homolog 3
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1668,487,634 - 68,548,718 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IEA)
nucleus  (IEA)

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
PER3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1668,487,634 - 68,548,718 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
PER3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3817,784,291 - 7,845,177 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl17,784,291 - 7,845,177 (+)EnsemblGRCh38hg38GRCh38
GRCh3717,844,351 - 7,905,237 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3617,767,350 - 7,827,824 (+)NCBINCBI36Build 36hg18NCBI36
Build 3417,779,028 - 7,839,503NCBI
Celera16,952,489 - 7,012,918 (+)NCBICelera
Cytogenetic Map1p36.23NCBI
HuRef16,993,003 - 7,053,532 (+)NCBIHuRef
CHM1_117,832,500 - 7,892,974 (+)NCBICHM1_1
T2T-CHM13v2.017,315,337 - 7,376,224 (+)NCBIT2T-CHM13v2.0
Per3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394151,081,475 - 151,129,167 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4151,088,109 - 151,129,122 (-)EnsemblGRCm39 Ensembl
GRCm384150,997,018 - 151,044,707 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4151,003,652 - 151,044,665 (-)EnsemblGRCm38mm10GRCm38
MGSCv374150,377,764 - 150,418,731 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv364149,848,512 - 149,888,389 (-)NCBIMGSCv36mm8
Celera4153,279,480 - 153,320,397 (-)NCBICelera
Cytogenetic Map4E2NCBI
cM Map481.53NCBI
Per3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85166,740,914 - 166,778,243 (-)NCBIGRCr8
mRatBN7.25161,460,228 - 161,495,404 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5161,459,533 - 161,495,607 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5164,177,009 - 164,211,658 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05165,993,418 - 166,028,287 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05165,955,653 - 165,990,302 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.05168,088,126 - 168,123,482 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5168,086,998 - 168,123,395 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05171,665,221 - 171,700,529 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45168,152,693 - 168,187,442 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.15168,163,026 - 168,197,630 (-)NCBI
Celera5159,712,426 - 159,747,156 (-)NCBICelera
Cytogenetic Map5q36NCBI
Per3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554865,059,773 - 5,101,637 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554865,058,602 - 5,101,480 (-)NCBIChiLan1.0ChiLan1.0
PER3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21220,381,214 - 220,442,021 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11219,022,337 - 219,083,038 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v016,547,667 - 6,607,905 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.117,795,549 - 7,855,922 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl17,795,552 - 7,855,922 (+)Ensemblpanpan1.1panPan2
PER3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1561,445,580 - 61,499,393 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl561,445,461 - 61,498,499 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha561,454,281 - 61,508,079 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0561,662,394 - 61,716,172 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl561,662,356 - 61,716,152 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1561,661,665 - 61,715,387 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0561,526,094 - 61,579,868 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0561,929,781 - 61,983,527 (+)NCBIUU_Cfam_GSD_1.0
Per3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505831,805,406 - 31,853,491 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366232,290,614 - 2,336,634 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366232,291,211 - 2,362,693 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PER3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.120123,912,773 - 123,970,440 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl20123,912,208 - 123,970,549 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605427,947,725 - 28,005,720 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Per3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248183,967,333 - 4,007,739 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248183,959,639 - 4,007,739 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in PER3
1097 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium 4 2
Low 10 4 3 5 2 19 2 1 3
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: XM_021095271   ⟹   XP_020950930
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1668,487,634 - 68,548,718 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021095272   ⟹   XP_020950931
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1668,487,634 - 68,548,705 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021095273   ⟹   XP_020950932
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1668,487,634 - 68,539,647 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021095274   ⟹   XP_020950933
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1668,487,634 - 68,539,647 (+)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_020950930   ⟸   XM_021095271
- Peptide Label: isoform X1
- UniProtKB: A0A480SPB4 (UniProtKB/TrEMBL),   A0A8D0TYG3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020950931   ⟸   XM_021095272
- Peptide Label: isoform X2
- UniProtKB: A0A480QJA7 (UniProtKB/TrEMBL),   A0A480SPB4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020950932   ⟸   XM_021095273
- Peptide Label: isoform X3
- UniProtKB: A0A480SPB4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020950933   ⟸   XM_021095274
- Peptide Label: isoform X4
- UniProtKB: A0A480SPB4 (UniProtKB/TrEMBL)
- Sequence:
Protein Domains
PAS


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000028572 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00015021722 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000027190 ENTREZGENE
  ENSSSCT00000027190.4 UniProtKB/TrEMBL
  ENSSSCT00000104125.1 UniProtKB/TrEMBL
  ENSSSCT00015028666.1 UniProtKB/TrEMBL
Gene3D-CATH PAS domain UniProtKB/TrEMBL
InterPro PAS UniProtKB/TrEMBL
  PAS-like_dom_sf UniProtKB/TrEMBL
  PAS_fold_3 UniProtKB/TrEMBL
  Per1-3_PAS-A UniProtKB/TrEMBL
  Period_circadian-like_C UniProtKB/TrEMBL
NCBI Gene PER3 ENTREZGENE
PANTHER PERIOD CIRCADIAN PROTEIN UniProtKB/TrEMBL
  PTHR11269:SF13 UniProtKB/TrEMBL
Pfam PAS_3 UniProtKB/TrEMBL
  Per3-like_PAS-A UniProtKB/TrEMBL
  Period_C UniProtKB/TrEMBL
PROSITE PAS UniProtKB/TrEMBL
SMART PAS UniProtKB/TrEMBL
Superfamily-SCOP SSF55785 UniProtKB/TrEMBL
UniProt A0A480QJA7 ENTREZGENE, UniProtKB/TrEMBL
  A0A480SPB4 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0TYG3 ENTREZGENE, UniProtKB/TrEMBL
  A0A8W4FLX0_PIG UniProtKB/TrEMBL
  I3LSH1_PIG UniProtKB/TrEMBL