Nucb1 (nucleobindin 1) - Rat Genome Database

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Gene: Nucb1 (nucleobindin 1) Rattus norvegicus
Analyze
Symbol: Nucb1
Name: nucleobindin 1
RGD ID: 620030
Description: Enables G-protein alpha-subunit binding activity; calcium ion binding activity; and guanyl-nucleotide exchange factor activity. Involved in regulation of protein targeting and small GTPase-mediated signal transduction. Located in Golgi apparatus; cytoplasmic vesicle; and extracellular space. Is extrinsic component of Golgi membrane. Orthologous to human NUCB1 (nucleobindin 1); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; acrylamide.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: bone 63 kDa calcium-binding protein; CALNUC; Nucb; nucleobindin; nucleobindin-1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81105,104,793 - 105,135,730 (-)NCBIGRCr8
mRatBN7.2195,968,325 - 95,999,183 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl195,968,326 - 96,003,220 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1101,353,752 - 101,373,866 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01109,826,428 - 109,846,542 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01103,116,822 - 103,136,934 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01101,480,160 - 101,511,029 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1101,480,145 - 101,500,850 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01102,559,072 - 102,579,628 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4195,961,163 - 95,981,910 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1196,039,273 - 96,060,021 (-)NCBI
Celera190,224,246 - 90,244,279 (-)NCBICelera
Cytogenetic Map1q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Nucb1RatStevens-Johnson syndrome  ISONUCB1 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:25811541

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Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Nucb1Rat1,2-dimethylhydrazine multiple interactionsISONucb1 (Mus musculus)6480464[1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of NUCB1 mRNACTDPMID:22206623
Nucb1Rat17alpha-ethynylestradiol affects expressionISONucb1 (Mus musculus)6480464Ethinyl Estradiol affects the expression of NUCB1 mRNACTDPMID:17555576
Nucb1Rat17alpha-ethynylestradiol multiple interactionsISONucb1 (Mus musculus)6480464[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of NUCB1 mRNACTDPMID:17942748
Nucb1Rat17alpha-ethynylestradiol increases expressionISONucb1 (Mus musculus)6480464Ethinyl Estradiol results in increased expression of NUCB1 mRNACTDPMID:17942748
Nucb1Rat17beta-estradiol affects expressionISONUCB1 (Homo sapiens)6480464Estradiol affects the expression of NUCB1 mRNACTDPMID:22574217
Nucb1Rat17beta-estradiol decreases expressionISONucb1 (Mus musculus)6480464Estradiol results in decreased expression of NUCB1 mRNACTDPMID:39298647
Nucb1Rat17beta-hydroxy-5alpha-androstan-3-one decreases expressionISONucb1 (Mus musculus)6480464Dihydrotestosterone results in decreased expression of NUCB1 mRNACTDPMID:17023530
Nucb1Rat2,3,7,8-tetrachlorodibenzodioxine multiple interactionsISONucb1 (Mus musculus)6480464[Tetrachlorodibenzodioxin binds to AHR protein] which results in increased expression of NUCB1 mRNA and [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of NUCB1 mRNACTDPMID:16214954 and PMID:17942748
Nucb1Rat2,3,7,8-tetrachlorodibenzodioxine increases expressionEXP 6480464Tetrachlorodibenzodioxin results in increased expression of NUCB1 mRNACTDPMID:33387578 and PMID:34747641
Nucb1Rat2,3,7,8-tetrachlorodibenzodioxine increases expressionISONucb1 (Mus musculus)6480464Tetrachlorodibenzodioxin results in increased expression of NUCB1 mRNACTDPMID:15328365 more ...
Nucb1Rat2,3,7,8-tetrachlorodibenzodioxine affects expressionISONucb1 (Mus musculus)6480464Tetrachlorodibenzodioxin affects the expression of NUCB1 mRNACTDPMID:21570461
Nucb1Rat2,3,7,8-tetrachlorodibenzodioxine increases expressionISONUCB1 (Homo sapiens)6480464Tetrachlorodibenzodioxin results in increased expression of NUCB1 mRNACTDPMID:21632981
Nucb1Rat4,4'-sulfonyldiphenol decreases expressionISONucb1 (Mus musculus)6480464bisphenol S results in decreased expression of NUCB1 mRNACTDPMID:39298647
Nucb1Rat6-propyl-2-thiouracil decreases expressionEXP 6480464Propylthiouracil results in decreased expression of NUCB1 mRNACTDPMID:36843608
Nucb1Ratacrolein multiple interactionsISONUCB1 (Homo sapiens)6480464[Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of NUCB1 mRNA more ...CTDPMID:32699268 and PMID:32845096
Nucb1Ratacrylamide increases expressionEXP 6480464Acrylamide results in increased expression of NUCB1 mRNACTDPMID:28959563
Nucb1Ratacrylamide increases expressionISONUCB1 (Homo sapiens)6480464Acrylamide results in increased expression of NUCB1 mRNACTDPMID:32763439
Nucb1Ratall-trans-retinoic acid increases expressionISONUCB1 (Homo sapiens)6480464Tretinoin results in increased expression of NUCB1 mRNACTDPMID:33167477
Nucb1Ratalpha-pinene multiple interactionsISONUCB1 (Homo sapiens)6480464[Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of NUCB1 mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased oxidation of NUCB1 mRNACTDPMID:32699268
Nucb1Ratammonium chloride affects expressionEXP 6480464Ammonium Chloride affects the expression of NUCB1 mRNACTDPMID:16483693

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Biological Process

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Nucb1Ratregulation of protein targeting  IDA 9831132 RGD 
Nucb1Ratsmall GTPase-mediated signal transduction involved_inIDA 14929204PMID:21653697UniProt 

Cellular Component
1 to 20 of 21 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Nucb1Ratcytoplasm located_inIEAUniProtKB-SubCell:SL-00861600115GO_REF:0000044UniProtGO_REF:0000044
Nucb1Ratcytoplasm located_inIEAUniProtKB-KW:KW-09631600115GO_REF:0000043UniProtGO_REF:0000043
Nucb1Ratcytoplasm located_inIEAARBA:ARBA000269711600115GO_REF:0000117UniProtGO_REF:0000117
Nucb1Ratearly endosome  IDA 9831132 RGD 
Nucb1Ratendomembrane system located_inIEAARBA:ARBA000289531600115GO_REF:0000117UniProtGO_REF:0000117
Nucb1Ratendoplasmic reticulum-Golgi intermediate compartment located_inIEAUniProtKB:Q02818 and ensembl:ENSP000003859231600115GO_REF:0000107EnsemblGO_REF:0000107
Nucb1Ratendoplasmic reticulum-Golgi intermediate compartment is_active_inIBAPANTHER:PTN001059206 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Nucb1Ratendoplasmic reticulum-Golgi intermediate compartment located_inISONUCB1 (Homo sapiens)1624291 PMID:15308636RGDPMID:15308636
Nucb1Ratextracellular region  IDA 9831129 RGD 
Nucb1Ratextracellular region located_inIEAUniProtKB-KW:KW-09641600115GO_REF:0000043UniProtGO_REF:0000043
Nucb1Ratextracellular region located_inIEAUniProtKB-SubCell:SL-02431600115GO_REF:0000044UniProtGO_REF:0000044
Nucb1Ratextracellular space  IDA 9831143 RGD 
Nucb1Ratextrinsic component of Golgi membrane  IDA 9831131 RGD 
Nucb1RatGolgi apparatus located_inIEAUniProtKB-SubCell:SL-01321600115GO_REF:0000044UniProtGO_REF:0000044
Nucb1RatGolgi apparatus located_inIEAUniProtKB-KW:KW-03331600115GO_REF:0000043UniProtGO_REF:0000043
Nucb1RatGolgi cisterna membrane  IDA 9831131 RGD 
Nucb1RatGolgi-associated vesicle  IDA 9831131 RGD 
Nucb1Ratintracellular membrane-bounded organelle located_inIEAARBA:ARBA000290851600115GO_REF:0000117UniProtGO_REF:0000117
Nucb1Ratlumenal side of Golgi membrane  IDA 9831131 RGD 
Nucb1Ratmembrane located_inIEAUniProtKB-KW:KW-04721600115GO_REF:0000043UniProtGO_REF:0000043
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Molecular Function
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#
Reference Title
Reference Citation
1. A systematic analysis of 40 random genes in cultured vascular smooth muscle subtypes reveals a heterogeneity of gene expression and identifies the tight junction gene zonula occludens 2 as a marker of epithelioid "pup" smooth muscle cells and a participant in carotid neointimal formation. Adams LD, etal., Arterioscler Thromb Vasc Biol 1999 Nov;19(11):2600-8.
2. Calnuc binds to LRP9 and affects its endosomal sorting. Brodeur J, etal., Traffic. 2009 Aug;10(8):1098-114. doi: 10.1111/j.1600-0854.2009.00933.x. Epub 2009 May 30.
3. Proteomic analysis of cisplatin-induced cochlear damage: methods and early changes in protein expression. Coling DE, etal., Hear Res. 2007 Apr;226(1-2):140-56. Epub 2007 Jan 24.
4. Nucleobindin-2/nesfatin in the endocrine pancreas: distribution and relationship to glycaemic state. Foo KS, etal., J Endocrinol. 2010 Mar;204(3):255-63. doi: 10.1677/JOE-09-0254. Epub 2009 Dec 23.
5. G Protein binding sites on Calnuc (nucleobindin 1) and NUCB2 (nucleobindin 2) define a new class of G(alpha)i-regulatory motifs. Garcia-Marcos M, etal., J Biol Chem. 2011 Aug 12;286(32):28138-49. doi: 10.1074/jbc.M110.204099. Epub 2011 Jun 8.
6. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
7. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
8. Calnuc, an EF-hand Ca(2+)-binding protein, is stored and processed in the Golgi and secreted by the constitutive-like pathway in AtT20 cells. Lavoie C, etal., Mol Endocrinol. 2002 Nov;16(11):2462-74.
9. The mammalian calcium-binding protein, nucleobindin (CALNUC), is a Golgi resident protein. Lin P, etal., J Cell Biol. 1998 Jun 29;141(7):1515-27.
10. Overexpression of CALNUC (nucleobindin) increases agonist and thapsigargin releasable Ca2+ storage in the Golgi. Lin P, etal., J Cell Biol. 1999 Apr 19;145(2):279-89.
11. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
12. Nucleobindin is produced by bone cells and secreted into the osteoid, with a potential role as a modulator of matrix maturation. Petersson U, etal., Bone. 2004 Jun;34(6):949-60.
13. GOA pipeline RGD automated data pipeline
14. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
15. Isolation, characterization, and primary structure of a calcium-binding 63-kDa bone protein. Wendel M, etal., J Biol Chem 1995 Mar 17;270(11):6125-33.
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PMID:10639138   PMID:12477932   PMID:15308636   PMID:16502470   PMID:16641100   PMID:19199708   PMID:19946888   PMID:20679342   PMID:23533145   PMID:23955309   PMID:25002582   PMID:25736948  
PMID:26666627  



Nucb1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81105,104,793 - 105,135,730 (-)NCBIGRCr8
mRatBN7.2195,968,325 - 95,999,183 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl195,968,326 - 96,003,220 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1101,353,752 - 101,373,866 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01109,826,428 - 109,846,542 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01103,116,822 - 103,136,934 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01101,480,160 - 101,511,029 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1101,480,145 - 101,500,850 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01102,559,072 - 102,579,628 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4195,961,163 - 95,981,910 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1196,039,273 - 96,060,021 (-)NCBI
Celera190,224,246 - 90,244,279 (-)NCBICelera
Cytogenetic Map1q22NCBI
NUCB1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381948,900,312 - 48,923,372 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1948,900,050 - 48,923,473 (+)EnsemblGRCh38hg38GRCh38
GRCh371949,403,569 - 49,426,629 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361954,091,637 - 54,118,340 (+)NCBINCBI36Build 36hg18NCBI36
Build 341954,095,852 - 54,118,337NCBI
Celera1946,270,663 - 46,293,902 (+)NCBICelera
Cytogenetic Map19q13.33NCBI
HuRef1945,779,769 - 45,802,972 (+)NCBIHuRef
CHM1_11949,405,174 - 49,428,729 (+)NCBICHM1_1
T2T-CHM13v2.01951,895,140 - 51,918,232 (+)NCBIT2T-CHM13v2.0
Nucb1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39745,142,300 - 45,159,813 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl745,139,882 - 45,159,830 (-)EnsemblGRCm39 Ensembl
GRCm38745,492,674 - 45,510,408 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl745,490,458 - 45,510,406 (-)EnsemblGRCm38mm10GRCm38
MGSCv37752,748,044 - 52,765,778 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36745,361,150 - 45,378,372 (-)NCBIMGSCv36mm8
Celera740,949,201 - 40,966,928 (-)NCBICelera
Cytogenetic Map7B3NCBI
cM Map729.33NCBI
Nucb1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555591,722,411 - 1,740,596 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555591,723,986 - 1,739,776 (-)NCBIChiLan1.0ChiLan1.0
NUCB1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22055,003,893 - 55,026,955 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11956,930,112 - 56,953,069 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01945,900,098 - 45,923,056 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11954,831,582 - 54,856,711 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1954,832,426 - 54,855,962 (-)Ensemblpanpan1.1panPan2
NUCB1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11107,453,965 - 107,476,458 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1107,454,636 - 107,476,375 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1106,976,497 - 106,999,075 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01107,978,613 - 108,001,223 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1107,978,615 - 108,001,085 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11107,646,057 - 107,668,201 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01107,292,476 - 107,315,053 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01108,128,088 - 108,150,670 (-)NCBIUU_Cfam_GSD_1.0
Nucb1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934921,305,942 - 21,327,980 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366642,924,719 - 2,945,178 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366642,924,186 - 2,946,035 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NUCB1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl654,180,038 - 54,209,930 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1654,186,610 - 54,209,457 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2650,119,224 - 50,141,964 (-)NCBISscrofa10.2Sscrofa10.2susScr3
NUCB1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1642,133,505 - 42,154,461 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366607322,017,037 - 22,040,686 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Nucb1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248325,071,869 - 5,085,623 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248325,073,022 - 5,085,493 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

.

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Variants in Nucb1
96 total Variants

Predicted Target Of
Summary Value
Count of predictions:148
Count of miRNA genes:100
Interacting mature miRNAs:119
Transcripts:ENSRNOT00000028390
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 45 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
2313059Bss55Bone structure and strength QTL 553.20.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)143284731118944897Rat
70209Niddm23Non-insulin dependent diabetes mellitus QTL 232.82blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)194494440198324465Rat
631688Hcas2Hepatocarcinoma susceptibility QTL 230.0001liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)15925874115540829Rat
1582234Gluco18Glucose level QTL 183.40.0003blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)178479925123479925Rat
1358359Sradr1Stress Responsive Adrenal Weight QTL 14.74adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)130882023123479925Rat
634314Niddm44Non-insulin dependent diabetes mellitus QTL 44blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)149393289199050459Rat
1578780Cm52Cardiac mass QTL 523.30.0001heart mass (VT:0007028)heart wet weight (CMO:0000069)181591954219808434Rat
1331793Bp200Blood pressure QTL 2003.71601arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)194494440172949803Rat
1578654Bss10Bone structure and strength QTL 104femur morphology trait (VT:0000559)femoral neck cortical cross-sectional area (CMO:0001702)149393172159356837Rat
2300324Fetw1Fetal weight QTL 112.10.005fetal growth trait (VT:0004201)fetal body weight (CMO:0002080)185424647100358001Rat

1 to 10 of 45 rows
RH127506  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2195,968,419 - 95,968,600 (+)MAPPERmRatBN7.2
Rnor_6.01101,480,255 - 101,480,435NCBIRnor6.0
Rnor_5.01102,559,167 - 102,559,347UniSTSRnor5.0
RGSC_v3.4195,961,257 - 95,961,437UniSTSRGSC3.4
Celera190,224,340 - 90,224,520UniSTS
RH 3.4 Map1909.6UniSTS
Cytogenetic Map1q22UniSTS




alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31



Ensembl Acc Id: ENSRNOT00000028390   ⟹   ENSRNOP00000028390
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl195,968,327 - 95,988,963 (-)Ensembl
Rnor_6.0 Ensembl1101,480,145 - 101,500,850 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000079633   ⟹   ENSRNOP00000075192
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl195,968,326 - 96,003,220 (-)Ensembl
RefSeq Acc Id: NM_053463   ⟹   NP_445915
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81105,104,793 - 105,125,430 (-)NCBI
mRatBN7.2195,968,325 - 95,988,962 (-)NCBI
Rnor_6.01101,480,161 - 101,500,284 (-)NCBI
Rnor_5.01102,559,072 - 102,579,628 (-)NCBI
RGSC_v3.4195,961,163 - 95,981,910 (-)RGD
Celera190,224,246 - 90,244,279 (-)RGD
Sequence:
RefSeq Acc Id: XM_006229164   ⟹   XP_006229226
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81105,104,793 - 105,125,395 (-)NCBI
mRatBN7.2195,968,325 - 95,988,958 (-)NCBI
Rnor_6.01101,480,160 - 101,500,731 (-)NCBI
Rnor_5.01102,559,072 - 102,579,628 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017589801   ⟹   XP_017445290
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81105,104,793 - 105,135,725 (-)NCBI
mRatBN7.2195,968,325 - 95,999,183 (-)NCBI
Rnor_6.01101,480,160 - 101,511,029 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017589802   ⟹   XP_017445291
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81105,104,793 - 105,135,730 (-)NCBI
mRatBN7.2195,968,325 - 95,999,182 (-)NCBI
Rnor_6.01101,480,160 - 101,511,029 (-)NCBI
Sequence:
RefSeq Acc Id: NP_445915   ⟸   NM_053463
- Peptide Label: precursor
- UniProtKB: P97623 (UniProtKB/Swiss-Prot),   Q497A4 (UniProtKB/Swiss-Prot),   Q63083 (UniProtKB/Swiss-Prot),   A6JB42 (UniProtKB/TrEMBL),   A0A8L2UKK1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006229226   ⟸   XM_006229164
- Peptide Label: isoform X3
- UniProtKB: A0A8L2UKK1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017445291   ⟸   XM_017589802
- Peptide Label: isoform X2
- UniProtKB: A0A0G2K9Z3 (UniProtKB/TrEMBL),   A0A8L2UKK1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017445290   ⟸   XM_017589801
- Peptide Label: isoform X1
- UniProtKB: A0A8L2UKK1 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000028390   ⟸   ENSRNOT00000028390
EF-hand

Name Modeler Protein Id AA Range Protein Structure
AF-Q63083-F1-model_v2 AlphaFold Q63083 1-459 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

RGD ID:13690042
Promoter ID:EPDNEW_R567
Type:initiation region
Name:Nucb1_1
Description:nucleobindin 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01101,500,796 - 101,500,856EPDNEW


1 to 32 of 32 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-59679 BioCyc
Ensembl Genes ENSRNOG00000020889 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000028390 ENTREZGENE
  ENSRNOT00000079633 ENTREZGENE
Gene3D-CATH EF-hand UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7930904 IMAGE-MGC_LOAD
InterPro EF-hand-dom_pair UniProtKB/Swiss-Prot
  EF_Hand_1_Ca_BS UniProtKB/Swiss-Prot
  EF_hand_dom UniProtKB/Swiss-Prot
  Nucleobindin UniProtKB/Swiss-Prot
KEGG Report rno:84595 UniProtKB/Swiss-Prot
MGC_CLONE MGC:124586 IMAGE-MGC_LOAD
NCBI Gene 84595 ENTREZGENE
PANTHER PTHR19237 UniProtKB/Swiss-Prot
  PTHR19237:SF21 UniProtKB/Swiss-Prot
PhenoGen Nucb1 PhenoGen
PROSITE EF_HAND_1 UniProtKB/Swiss-Prot
  EF_HAND_2 UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000020889 RatGTEx
Superfamily-SCOP SSF47473 UniProtKB/Swiss-Prot
UniProt A0A0G2K9Z3 ENTREZGENE, UniProtKB/TrEMBL
  A0A8L2UKK1 ENTREZGENE, UniProtKB/TrEMBL
  A6JB39_RAT UniProtKB/TrEMBL
  A6JB42 ENTREZGENE, UniProtKB/TrEMBL
  A6JB44_RAT UniProtKB/TrEMBL
  NUCB1_RAT UniProtKB/Swiss-Prot
  P97623 ENTREZGENE
  Q497A4 ENTREZGENE
  Q63083 ENTREZGENE
  Q6P6Q3_RAT UniProtKB/TrEMBL
UniProt Secondary P97623 UniProtKB/Swiss-Prot
  Q497A4 UniProtKB/Swiss-Prot
1 to 32 of 32 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2005-01-20 Nucb1  nucleobindin 1  Nucb  nucleobindin  Symbol and Name updated 1299863 APPROVED
2002-08-07 Nucb  nucleobindin      Symbol and Name status set to provisional 70820 PROVISIONAL

Note Type Note Reference
gene_expression expressed in calvaria of bone 633377