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Gene: Dclre1b (DNA cross-link repair 1B) Rattus norvegicus

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Symbol:

Dclre1b

Name:

DNA cross-link repair 1B

RGD ID:

1310343

Description:

Predicted to enable several functions, including 5'-3' DNA exonuclease activity; beta-lactamase activity; and protein homodimerization activity. Predicted to be involved in DNA metabolic process. Predicted to be located in centrosome; chromosome, telomeric region; and nuclear body. Human ortholog(s) of this gene implicated in dyskeratosis congenita. Orthologous to human DCLRE1B (DNA cross-link repair 1B); INTERACTS WITH 17beta-estradiol; bisphenol A; fenvalerate.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

5' exonuclease Apollo; beta-lactamase MBLAC2; DNA cross-link repair 1B protein; DNA cross-link repair 1B, PSO2 homolog; DNA cross-link repair 1B, PSO2 homolog (S. cerevisiae); LOC310745; MGC114481; SNM1 homolog B

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	DCLRE1B (DNA cross-link repair 1B)	HGNC	EggNOG, Ensembl, HomoloGene, NCBI, OMA, OrthoDB, OrthoMCL, Panther, Treefam
Mus musculus (house mouse):	Dclre1b (DNA cross-link repair 1B)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Dclre1b (DNA cross-link repair 1B)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	DCLRE1B (DNA cross-link repair 1B)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	DCLRE1B (DNA cross-link repair 1B)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	DCLRE1B (DNA cross-link repair 1B)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	DCLRE1B (DNA cross-link repair 1B)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	DCLRE1C (DNA cross-link repair 1C)	HGNC	Inparanoid
Homo sapiens (human):	NDUFA13 (NADH:ubiquinone oxidoreductase subunit A13)	HGNC	OMA
Alliance orthologs ³
Homo sapiens (human):	DCLRE1B (DNA cross-link repair 1B)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Dclre1b (DNA cross-link repair 1B)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	dclre1b (DNA cross-link repair 1B)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	mrt-1	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	dclre1b	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PANTHER\|PhylomeDB)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	2	193,998,350 - 194,006,873 (-)	NCBI		GRCr8
mRatBN7.2	2	191,309,909 - 191,318,399 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	2	191,309,913 - 191,318,423 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	2	198,906,905 - 198,915,386 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	2	196,779,634 - 196,788,115 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	2	191,596,608 - 191,605,089 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	2	206,285,085 - 206,293,599 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	2	206,285,089 - 206,293,599 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	2	225,708,795 - 225,717,309 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	2	199,025,718 - 199,034,230 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	2	198,988,471 - 198,996,984 (-)	NCBI
Celera	2	183,781,669 - 183,790,181 (-)	NCBI		Celera
Cytogenetic Map	2	q34	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Dclre1b	Rat	Autosomal Recessive Dyskeratosis Congenita		ISO	DCLRE1B (Homo sapiens)	8554872	ClinVar Annotator: match by term: Autosomal recessive dyskeratosis congenita	ClinVar	PMID:25741868 and PMID:28492532
Dclre1b	Rat	Autosomal Recessive Dyskeratosis Congenita 8		ISO	DCLRE1B (Homo sapiens)	8554872	ClinVar Annotator: match by term: Dyskeratosis congenita and autosomal recessive 8	ClinVar	PMID:28492532 and PMID:35007328
Dclre1b	Rat	Fanconi anemia complementation group C		ISO	DCLRE1B (Homo sapiens)	8554872	ClinVar Annotator: match by term: Fanconi anemia complementation group C	ClinVar	PMID:25741868
Dclre1b	Rat	genetic disease		ISO	DCLRE1B (Homo sapiens)	8554872	ClinVar Annotator: match by term: Inborn genetic diseases	ClinVar	PMID:25741868 and PMID:28492532
Dclre1b	Rat	hereditary spastic paraplegia		ISO	DCLRE1B (Homo sapiens)	8554872	ClinVar Annotator: match by term: Hereditary spastic paraplegia	ClinVar	PMID:25741868 and PMID:28492532
Dclre1b	Rat	hereditary spastic paraplegia 47		ISO	DCLRE1B (Homo sapiens)	8554872	ClinVar Annotator: match by term: Hereditary spastic paraplegia 47	ClinVar	PMID:22290197 more ...
Dclre1b	Rat	Hoyeraal Hreidarsson Syndrome		ISO	DCLRE1B (Homo sapiens)	8554872	ClinVar Annotator: match by term: Hoyeraal-Hreidarsson syndrome	ClinVar	PMID:17576681 more ...
Dclre1b	Rat	RASopathy		ISO	DCLRE1B (Homo sapiens)	8554872	ClinVar Annotator: match by term: RASopathy	ClinVar	PMID:28492532

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Dclre1b	Rat	Autosomal Recessive Dyskeratosis Congenita 8		ISO	DCLRE1B (Homo sapiens)	7240710		OMIM

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Dclre1b	Rat	17beta-estradiol	multiple interactions	EXP		6480464	[bisphenol A co-treated with Estradiol] results in increased expression of DCLRE1B mRNA	CTD	PMID:26496021
Dclre1b	Rat	2,3,7,8-tetrachlorodibenzodioxine	increases expression	ISO	Dclre1b (Mus musculus)	6480464	Tetrachlorodibenzodioxin results in increased expression of DCLRE1B mRNA	CTD	PMID:19465110
Dclre1b	Rat	2,3,7,8-tetrachlorodibenzodioxine	affects expression	ISO	Dclre1b (Mus musculus)	6480464	Tetrachlorodibenzodioxin affects the expression of DCLRE1B mRNA	CTD	PMID:21570461
Dclre1b	Rat	4,4'-diaminodiphenylmethane	decreases expression	ISO	Dclre1b (Mus musculus)	6480464	4 and 4'-diaminodiphenylmethane results in decreased expression of DCLRE1B mRNA	CTD	PMID:18648102
Dclre1b	Rat	all-trans-retinoic acid	decreases expression	ISO	DCLRE1B (Homo sapiens)	6480464	Tretinoin results in decreased expression of DCLRE1B mRNA	CTD	PMID:33167477
Dclre1b	Rat	arecoline	decreases expression	ISO	DCLRE1B (Homo sapiens)	6480464	Arecoline results in decreased expression of DCLRE1B mRNA	CTD	PMID:17682004
Dclre1b	Rat	arsane	affects methylation	ISO	DCLRE1B (Homo sapiens)	6480464	Arsenic affects the methylation of DCLRE1B gene	CTD	PMID:25304211
Dclre1b	Rat	arsenic atom	affects methylation	ISO	DCLRE1B (Homo sapiens)	6480464	Arsenic affects the methylation of DCLRE1B gene	CTD	PMID:25304211
Dclre1b	Rat	benzo[a]pyrene	increases expression	ISO	Dclre1b (Mus musculus)	6480464	Benzo(a)pyrene results in increased expression of DCLRE1B mRNA	CTD	PMID:22228805
Dclre1b	Rat	benzo[a]pyrene	increases expression	ISO	DCLRE1B (Homo sapiens)	6480464	Benzo(a)pyrene results in increased expression of DCLRE1B mRNA	CTD	PMID:32234424
Dclre1b	Rat	benzo[a]pyrene diol epoxide I	decreases expression	ISO	DCLRE1B (Homo sapiens)	6480464	7 more ...	CTD	PMID:20382639
Dclre1b	Rat	bisphenol A	multiple interactions	EXP		6480464	[bisphenol A co-treated with Estradiol] results in increased expression of DCLRE1B mRNA	CTD	PMID:26496021
Dclre1b	Rat	bisphenol A	decreases expression	ISO	DCLRE1B (Homo sapiens)	6480464	bisphenol A results in decreased expression of DCLRE1B mRNA	CTD	PMID:29275510
Dclre1b	Rat	bisphenol A	decreases expression	EXP		6480464	bisphenol A results in decreased expression of DCLRE1B mRNA	CTD	PMID:25181051 and PMID:34947998
Dclre1b	Rat	cannabidiol	decreases expression	ISO	DCLRE1B (Homo sapiens)	6480464	Cannabidiol results in decreased expression of DCLRE1B mRNA	CTD	PMID:36519830
Dclre1b	Rat	CGP 52608	multiple interactions	ISO	DCLRE1B (Homo sapiens)	6480464	CGP 52608 promotes the reaction [RORA protein binds to DCLRE1B gene]	CTD	PMID:28238834
Dclre1b	Rat	coumestrol	multiple interactions	ISO	DCLRE1B (Homo sapiens)	6480464	[Coumestrol co-treated with 2 more ...	CTD	PMID:19167446
Dclre1b	Rat	coumestrol	increases expression	ISO	DCLRE1B (Homo sapiens)	6480464	Coumestrol results in increased expression of DCLRE1B mRNA	CTD	PMID:19167446
Dclre1b	Rat	cyclosporin A	decreases expression	ISO	DCLRE1B (Homo sapiens)	6480464	Cyclosporine results in decreased expression of DCLRE1B mRNA	CTD	PMID:25562108
Dclre1b	Rat	Dibutyl phosphate	affects expression	ISO	DCLRE1B (Homo sapiens)	6480464	di-n-butylphosphoric acid affects the expression of DCLRE1B mRNA	CTD	PMID:37042841
Dclre1b	Rat	dioxygen	increases expression	ISO	Dclre1b (Mus musculus)	6480464	Oxygen deficiency results in increased expression of DCLRE1B mRNA	CTD	PMID:22629407
Dclre1b	Rat	dioxygen	decreases expression	ISO	DCLRE1B (Homo sapiens)	6480464	Oxygen deficiency results in decreased expression of DCLRE1B mRNA	CTD	PMID:26516004
Dclre1b	Rat	dioxygen	multiple interactions	ISO	Dclre1b (Mus musculus)	6480464	Oxygen inhibits the reaction [Oxygen deficiency results in increased expression of DCLRE1B mRNA]	CTD	PMID:22629407
Dclre1b	Rat	doxorubicin	decreases expression	ISO	DCLRE1B (Homo sapiens)	6480464	Doxorubicin results in decreased expression of DCLRE1B mRNA	CTD	PMID:29803840
Dclre1b	Rat	Enterolactone	multiple interactions	ISO	DCLRE1B (Homo sapiens)	6480464	[Coumestrol co-treated with 2 and 3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of DCLRE1B mRNA	CTD	PMID:19167446
Dclre1b	Rat	ethanol	affects expression	ISO	Dclre1b (Mus musculus)	6480464	Ethanol affects the expression of DCLRE1B mRNA	CTD	PMID:30319688
Dclre1b	Rat	fenvalerate	increases expression	EXP		6480464	fenvalerate results in increased expression of DCLRE1B mRNA	CTD	PMID:30307764
Dclre1b	Rat	formaldehyde	decreases expression	ISO	DCLRE1B (Homo sapiens)	6480464	Formaldehyde results in decreased expression of DCLRE1B mRNA	CTD	PMID:20655997
Dclre1b	Rat	gentamycin	increases expression	EXP		6480464	Gentamicins results in increased expression of DCLRE1B mRNA	CTD	PMID:33387578
Dclre1b	Rat	glyphosate	increases expression	ISO	Dclre1b (Mus musculus)	6480464	Glyphosate results in increased expression of DCLRE1B mRNA	CTD	PMID:35897073
Dclre1b	Rat	leflunomide	decreases expression	ISO	DCLRE1B (Homo sapiens)	6480464	leflunomide results in decreased expression of DCLRE1B mRNA	CTD	PMID:28988120
Dclre1b	Rat	maneb	multiple interactions	ISO	Dclre1b (Mus musculus)	6480464	[Maneb co-treated with Paraquat] results in decreased expression of DCLRE1B mRNA	CTD	PMID:36117858
Dclre1b	Rat	N-ethyl-N-nitrosourea	increases mutagenesis	ISO	Dclre1b (Mus musculus)	6480464	Ethylnitrosourea results in increased mutagenesis of DCLRE1B mRNA	CTD	PMID:27776689
Dclre1b	Rat	nickel atom	increases expression	ISO	DCLRE1B (Homo sapiens)	6480464	Nickel results in increased expression of DCLRE1B mRNA	CTD	PMID:24768652 and PMID:25583101
Dclre1b	Rat	oxaliplatin	multiple interactions	EXP		6480464	[oxaliplatin co-treated with Topotecan] results in decreased expression of DCLRE1B mRNA	CTD	PMID:25729387
Dclre1b	Rat	paracetamol	increases expression	ISO	DCLRE1B (Homo sapiens)	6480464	Acetaminophen results in increased expression of DCLRE1B mRNA	CTD	PMID:22230336
Dclre1b	Rat	paracetamol	increases expression	EXP		6480464	Acetaminophen results in increased expression of DCLRE1B mRNA	CTD	PMID:33387578
Dclre1b	Rat	paraquat	multiple interactions	ISO	Dclre1b (Mus musculus)	6480464	[Maneb co-treated with Paraquat] results in decreased expression of DCLRE1B mRNA	CTD	PMID:36117858
Dclre1b	Rat	perfluorohexanesulfonic acid	decreases expression	ISO	Dclre1b (Mus musculus)	6480464	perfluorohexanesulfonic acid results in decreased expression of DCLRE1B mRNA	CTD	PMID:37995155
Dclre1b	Rat	resveratrol	multiple interactions	ISO	DCLRE1B (Homo sapiens)	6480464	[Coumestrol co-treated with resveratrol] results in increased expression of DCLRE1B mRNA	CTD	PMID:19167446
Dclre1b	Rat	rifampicin	decreases expression	ISO	DCLRE1B (Homo sapiens)	6480464	Rifampin results in decreased expression of DCLRE1B mRNA	CTD	PMID:24552687
Dclre1b	Rat	sodium arsenite	increases expression	ISO	DCLRE1B (Homo sapiens)	6480464	sodium arsenite results in increased expression of DCLRE1B mRNA	CTD	PMID:28595984
Dclre1b	Rat	sodium arsenite	affects expression	ISO	DCLRE1B (Homo sapiens)	6480464	sodium arsenite affects the expression of DCLRE1B mRNA	CTD	PMID:34032870
Dclre1b	Rat	sodium arsenite	decreases expression	ISO	DCLRE1B (Homo sapiens)	6480464	sodium arsenite results in decreased expression of DCLRE1B mRNA	CTD	PMID:38568856
Dclre1b	Rat	titanium dioxide	increases methylation	ISO	Dclre1b (Mus musculus)	6480464	titanium dioxide results in increased methylation of DCLRE1B gene	CTD	PMID:35295148
Dclre1b	Rat	topotecan	decreases expression	EXP		6480464	Topotecan results in decreased expression of DCLRE1B mRNA	CTD	PMID:25729387
Dclre1b	Rat	topotecan	multiple interactions	EXP		6480464	[oxaliplatin co-treated with Topotecan] results in decreased expression of DCLRE1B mRNA	CTD	PMID:25729387
Dclre1b	Rat	triphenyl phosphate	affects expression	ISO	DCLRE1B (Homo sapiens)	6480464	triphenyl phosphate affects the expression of DCLRE1B mRNA	CTD	PMID:37042841
Dclre1b	Rat	valproic acid	increases expression	ISO	DCLRE1B (Homo sapiens)	6480464	Valproic Acid results in increased expression of DCLRE1B mRNA	CTD	PMID:23179753
Dclre1b	Rat	valproic acid	affects expression	ISO	DCLRE1B (Homo sapiens)	6480464	Valproic Acid affects the expression of DCLRE1B mRNA	CTD	PMID:25979313
Dclre1b	Rat	vinclozolin	decreases expression	EXP		6480464	vinclozolin results in decreased expression of DCLRE1B mRNA	CTD	PMID:23034163

Biological Process

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Dclre1b	Rat	biological_process		ND		1598407	02/2010: no relevant rat data	RGD
Dclre1b	Rat	DNA repair	involved_in	IEA	UniProtKB-KW:KW-0234	1600115	GO_REF:0000043	UniProt	GO_REF:0000043
Dclre1b	Rat	double-strand break repair via nonhomologous end joining	involved_in	IBA	PANTHER:PTN000581728 and dictyBase:DDB_G0277755	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033
Dclre1b	Rat	interstrand cross-link repair	involved_in	ISO	DCLRE1B (Homo sapiens)	1624291	PMID:20479256	RGD	PMID:20479256
Dclre1b	Rat	interstrand cross-link repair	involved_in	IBA	PANTHER:PTN000581728 more ...	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033
Dclre1b	Rat	interstrand cross-link repair	involved_in	IEA	UniProtKB:Q9H816 and ensembl:ENSP00000498042	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Dclre1b	Rat	protection from non-homologous end joining at telomere	involved_in	ISO	DCLRE1B (Homo sapiens)	1624291	PMID:16730175 and PMID:20479256	RGD	PMID:16730175 and PMID:20479256
Dclre1b	Rat	protection from non-homologous end joining at telomere	involved_in	ISO	Dclre1b (Mus musculus)	1624291	PMID:20551906 and PMID:20619712	RGD	PMID:20551906 and PMID:20619712
Dclre1b	Rat	protection from non-homologous end joining at telomere	involved_in	ISS	UniProtKB:Q9H816	1600115	GO_REF:0000024	UniProt	GO_REF:0000024
Dclre1b	Rat	protection from non-homologous end joining at telomere	involved_in	IEA	UniProtKB:Q9H816 and ensembl:ENSP00000498042	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Dclre1b	Rat	protection from non-homologous end joining at telomere	involved_in	ISS	UniProtKB:Q8C7W7	1600115	GO_REF:0000024	UniProt	GO_REF:0000024
Dclre1b	Rat	protection from non-homologous end joining at telomere	involved_in	IEA	UniProtKB:Q8C7W7 and ensembl:ENSMUSP00000029435	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Dclre1b	Rat	telomere capping	involved_in	ISO	DCLRE1B (Homo sapiens)	1624291	PMID:20479256	RGD	PMID:20479256
Dclre1b	Rat	telomere maintenance	involved_in	ISS	UniProtKB:Q9H816	1600115	GO_REF:0000024	UniProt	GO_REF:0000024
Dclre1b	Rat	telomere maintenance	involved_in	IBA	MGI:2156057 more ...	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033
Dclre1b	Rat	telomere maintenance	involved_in	ISO	DCLRE1B (Homo sapiens)	1624291	PMID:20655466	RGD	PMID:20655466
Dclre1b	Rat	telomere maintenance via telomere lengthening	involved_in	IEA	UniProtKB:Q9H816 and ensembl:ENSP00000498042	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Dclre1b	Rat	telomere maintenance via telomere lengthening	involved_in	ISO	DCLRE1B (Homo sapiens)	1624291	PMID:20479256	RGD	PMID:20479256
Dclre1b	Rat	telomeric 3' overhang formation	involved_in	IEA	UniProtKB:Q8C7W7 and ensembl:ENSMUSP00000029435	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Dclre1b	Rat	telomeric 3' overhang formation	involved_in	ISO	Dclre1b (Mus musculus)	1624291	PMID:20551906 and PMID:20619712	RGD	PMID:20551906 and PMID:20619712
Dclre1b	Rat	telomeric 3' overhang formation	involved_in	ISS	UniProtKB:Q8C7W7	1600115	GO_REF:0000024	UniProt	GO_REF:0000024
Dclre1b	Rat	telomeric loop formation	involved_in	IEA	UniProtKB:Q8C7W7 and ensembl:ENSMUSP00000029435	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Dclre1b	Rat	telomeric loop formation	involved_in	ISO	Dclre1b (Mus musculus)	1624291	PMID:20619712	RGD	PMID:20619712
Dclre1b	Rat	telomeric loop formation	involved_in	ISS	UniProtKB:Q8C7W7	1600115	GO_REF:0000024	UniProt	GO_REF:0000024

Cellular Component

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Dclre1b	Rat	centrosome	located_in	ISS	UniProtKB:Q9H816	1600115	GO_REF:0000024	UniProt	GO_REF:0000024
Dclre1b	Rat	centrosome	located_in	ISO	DCLRE1B (Homo sapiens)	1624291	PMID:19197158	RGD	PMID:19197158
Dclre1b	Rat	centrosome	located_in	IEA	UniProtKB:Q9H816 and ensembl:ENSP00000498042	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Dclre1b	Rat	chromosome, telomeric region	located_in	ISS	UniProtKB:Q8C7W7	1600115	GO_REF:0000024	UniProt	GO_REF:0000024
Dclre1b	Rat	chromosome, telomeric region	located_in	IEA	UniProtKB-SubCell:SL-0276	1600115	GO_REF:0000044	UniProt	GO_REF:0000044
Dclre1b	Rat	chromosome, telomeric region	located_in	ISO	DCLRE1B (Homo sapiens)	1624291	PMID:16730175 more ...	RGD	PMID:16730175 more ...
Dclre1b	Rat	chromosome, telomeric region	located_in	ISO	Dclre1b (Mus musculus)	1624291	PMID:20551906 and PMID:20619712	RGD	PMID:20551906 and PMID:20619712
Dclre1b	Rat	chromosome, telomeric region	located_in	ISS	UniProtKB:Q9H816	1600115	GO_REF:0000024	UniProt	GO_REF:0000024
Dclre1b	Rat	cytoplasm	located_in	IEA	UniProtKB-KW:KW-0963	1600115	GO_REF:0000043	UniProt	GO_REF:0000043
Dclre1b	Rat	nuclear body	located_in	IEA	UniProtKB:Q9H816 and ensembl:ENSP00000498042	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Dclre1b	Rat	nuclear body	located_in	ISO	DCLRE1B (Homo sapiens)	1624291		RGD	GO_REF:0000052
Dclre1b	Rat	nucleoplasm	located_in	ISO	DCLRE1B (Homo sapiens)	1624291		RGD	GO_REF:0000052
Dclre1b	Rat	nucleus	located_in	IEA	UniProtKB-SubCell:SL-0191	1600115	GO_REF:0000044	UniProt	GO_REF:0000044

Molecular Function

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Dclre1b	Rat	5'-3' DNA exonuclease activity	enables	IBA	PANTHER:PTN000581728 and UniProtKB:Q6PJP8	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033
Dclre1b	Rat	5'-3' exonuclease activity	enables	IEA	UniProtKB:Q9H816 and ensembl:ENSP00000498042	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Dclre1b	Rat	5'-3' exonuclease activity	enables	ISO	Dclre1b (Mus musculus)	1624291	PMID:20551906 and PMID:20619712	RGD	PMID:20551906 and PMID:20619712
Dclre1b	Rat	5'-3' exonuclease activity	enables	ISO	DCLRE1B (Homo sapiens)	1624291	PMID:16730175 more ...	RGD	PMID:16730175 more ...
Dclre1b	Rat	5'-3' exonuclease activity	enables	ISS	UniProtKB:Q9H816	1600115	GO_REF:0000024	UniProt	GO_REF:0000024
Dclre1b	Rat	5'-3' exonuclease activity	enables	ISS	UniProtKB:Q8C7W7	1600115	GO_REF:0000024	UniProt	GO_REF:0000024
Dclre1b	Rat	5'-3' exonuclease activity	enables	IEA	UniProtKB:Q8C7W7 and ensembl:ENSMUSP00000029435	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Dclre1b	Rat	beta-lactamase activity	enables	ISO	DCLRE1B (Homo sapiens)	1624291	PMID:31434986	RGD	PMID:31434986
Dclre1b	Rat	beta-lactamase activity	enables	ISS	UniProtKB:Q9H816	1600115	GO_REF:0000024	UniProt	GO_REF:0000024
Dclre1b	Rat	beta-lactamase activity	enables	IEA	UniProtKB:Q9H816 and ensembl:ENSP00000498042	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Dclre1b	Rat	damaged DNA binding	enables	IBA	PANTHER:PTN000581728 and SGD:S000004745	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033
Dclre1b	Rat	exonuclease activity	enables	IEA	UniProtKB-KW:KW-0269	1600115	GO_REF:0000043	UniProt	GO_REF:0000043
Dclre1b	Rat	protein binding	enables	ISO	DCLRE1B (Homo sapiens)	1624291	UniProtKB:O76024 more ...	RGD	PMID:16730175 more ...
Dclre1b	Rat	protein binding	enables	ISO	Dclre1b (Mus musculus)	1624291	UniProtKB:O35144 and PMID:20619712	RGD	PMID:20619712
Dclre1b	Rat	protein homodimerization activity	enables	IEA	UniProtKB:Q9H816 and ensembl:ENSP00000498042	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Dclre1b	Rat	protein homodimerization activity	enables	ISO	DCLRE1B (Homo sapiens)	1624291	PMID:20479256	RGD	PMID:20479256
Dclre1b	Rat	protein-containing complex binding	enables	ISO	DCLRE1B (Homo sapiens)	1624291	ComplexPortal:CPX-152 PMID:18202258	RGD	PMID:18202258
Dclre1b	Rat	protein-containing complex binding	enables	IEA	UniProtKB:Q9H816 and ensembl:ENSP00000498042	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
3.	Comprehensive gene review and curation	RGD comprehensive gene curation

PMID:12477932	PMID:16730175	PMID:18202258	PMID:19135898	PMID:19197158	PMID:20479256	PMID:20551906	PMID:20619712	PMID:20655466	PMID:22692201	PMID:24270157	PMID:25943107

Dclre1b
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	2	193,998,350 - 194,006,873 (-)	NCBI		GRCr8
mRatBN7.2	2	191,309,909 - 191,318,399 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	2	191,309,913 - 191,318,423 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	2	198,906,905 - 198,915,386 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	2	196,779,634 - 196,788,115 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	2	191,596,608 - 191,605,089 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	2	206,285,085 - 206,293,599 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	2	206,285,089 - 206,293,599 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	2	225,708,795 - 225,717,309 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	2	199,025,718 - 199,034,230 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	2	198,988,471 - 198,996,984 (-)	NCBI
Celera	2	183,781,669 - 183,790,181 (-)	NCBI		Celera
Cytogenetic Map	2	q34	NCBI

DCLRE1B
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	1	113,904,619 - 113,914,086 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	1	113,904,619 - 113,914,086 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	1	114,447,241 - 114,456,708 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	1	114,249,561 - 114,258,217 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	1	114,160,079 - 114,168,734	NCBI
Celera	1	112,677,139 - 112,685,932 (+)	NCBI		Celera
Cytogenetic Map	1	p13.2	NCBI
HuRef	1	112,306,040 - 112,314,841 (+)	NCBI		HuRef
CHM1_1	1	114,562,775 - 114,571,568 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	1	113,916,281 - 113,925,748 (+)	NCBI		T2T-CHM13v2.0

Dclre1b
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	3	103,707,921 - 103,716,703 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	3	103,707,921 - 103,716,760 (-)	Ensembl		GRCm39 Ensembl
GRCm38	3	103,800,605 - 103,809,387 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	3	103,800,605 - 103,809,444 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	3	103,604,528 - 103,613,310 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	3	103,929,666 - 103,938,448 (-)	NCBI		MGSCv36	mm8
Celera	3	106,003,520 - 106,012,334 (-)	NCBI		Celera
Cytogenetic Map	3	F2.2	NCBI
cM Map	3	45.52	NCBI

Dclre1b
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0	NW_004955435	17,173,975 - 17,179,986 (+)	NCBI	ChiLan1.0	ChiLan1.0

DCLRE1B
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	1	106,564,031 - 106,571,091 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	1	106,157,486 - 106,164,503 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	1	88,643,664 - 88,651,962 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	1	123,692,921 - 123,701,403 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	1	123,692,915 - 123,701,403 (-)	Ensembl	panpan1.1		panPan2

DCLRE1B
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	17	51,711,267 - 51,716,806 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	17	51,711,284 - 51,716,345 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	17	51,362,655 - 51,368,194 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	17	52,589,546 - 52,595,104 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	17	52,589,468 - 52,595,469 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	17	51,596,829 - 51,602,368 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	17	51,665,109 - 51,670,657 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	17	52,237,640 - 52,243,174 (+)	NCBI		UU_Cfam_GSD_1.0

DCLRE1B
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	4	106,646,011 - 106,656,452 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	4	106,646,591 - 106,656,490 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	4	116,854,880 - 116,861,827 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

DCLRE1B
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	20	19,750,106 - 19,757,190 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	20	19,748,898 - 19,756,901 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666038	22,518,633 - 22,527,397 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Variants in Dclre1b
40 total Variants

Predicted Target Of

	Summary Value
Count of predictions:	328
Count of miRNA genes:	210
Interacting mature miRNAs:	259
Transcripts:	ENSRNOT00000026213
Prediction methods:	Miranda, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1578648	Bss11	Bone structure and strength QTL 11	4.7		femur morphology trait (VT:0000559)	femoral neck cortical cross-sectional area (CMO:0001702)	2	114837527	211674221	Rat
1358356	Srcrt1	Stress Responsive Cort QTL1	3.66		blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	2	161699179	222436696	Rat
1331734	Bp204	Blood pressure QTL 204	3.61192		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	2	168358098	223265385	Rat
1298074	Bp164	Blood pressure QTL 164		0.003	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	42804607	202447032	Rat
1354648	Bp239	Blood pressure QTL 239		0.001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	66118463	226797303	Rat
1354649	Kidm17	Kidney mass QTL 17	2.9		kidney mass (VT:0002707)	calculated kidney weight (CMO:0000160)	2	81754530	227146641	Rat
10755499	Bp389	Blood pressure QTL 389	2.61		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	2	18960362	228801039	Rat
1298076	Bp166	Blood pressure QTL 166		0.0009	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	136445150	202447032	Rat
152025245	Scl81	Serum cholesterol level QTL 81	3.49		blood cholesterol amount (VT:0000180)		2	122609194	206936711	Rat
61458	Bp10	Blood pressure QTL 10	3.42		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	189020722	215287351	Rat
70162	Bp63	Blood pressure QTL 63	5.64		arterial blood pressure trait (VT:2000000)	blood pressure measurement (CMO:0000003)	2	169745596	214745596	Rat
1554319	Bmd2	Bone mineral density QTL 2	13.4	0.0001	lumbar vertebra area (VT:0010570)	lumbar vertebra cross-sectional area (CMO:0001689)	2	114837675	212549332	Rat
1581569	Uae32	Urinary albumin excretion QTL 32		0.0001	urine protein amount (VT:0005160)	urine albumin excretion rate (CMO:0000757)	2	78665619	219826953	Rat
1302793	Bw16	Body weight QTL 16	5	0.0001	body mass (VT:0001259)	body weight (CMO:0000012)	2	157142209	202446871	Rat
10043139	Iddm55	Insulin dependent diabetes mellitus QTL 55	3.1	0.0001	blood glucose amount (VT:0000188)	age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)	2	190602746	192625452	Rat
61467	Bp14	Blood pressure QTL 14	2.2		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	43154682	202446871	Rat
61469	Bp16	Blood pressure QTL 16	5.64		arterial blood pressure trait (VT:2000000)	blood pressure measurement (CMO:0000003)	2	169745596	214745596	Rat
70175	BpQTLCluster3	Blood pressure QTL cluster 3	4.128		arterial blood pressure trait (VT:2000000)	absolute change in systolic blood pressure (CMO:0000607)	2	135552573	202446871	Rat
1358900	Bw48	Body weight QTL 48	4.88		body mass (VT:0001259)	body weight (CMO:0000012)	2	157142078	211086598	Rat
4889834	Pur24	Proteinuria QTL 24	5.8	0.014	urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	2	184114274	202447032	Rat
1359031	Bp275	Blood pressure QTL 275			arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	2	185876309	219753474	Rat
1581499	Esta2	Estrogen-induced thymic atrophy QTL 2			thymus mass (VT:0004954)	thymus wet weight (CMO:0000855)	2	189599258	226936289	Rat
1331760	Bp206	Blood pressure QTL 206	3.62454		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	2	56043031	202447032	Rat
9589044	Scfw1	Subcutaneous fat weight QTL 1	5.8	0.001	subcutaneous adipose mass (VT:1000472)	abdominal subcutaneous fat pad weight (CMO:0002069)	2	182171407	227171407	Rat
8694435	Bw166	Body weight QTL 166	14.08	0.001	retroperitoneal fat pad mass (VT:0010430)	retroperitoneal fat pad weight to body weight ratio (CMO:0000635)	2	182171407	227171407	Rat
1359032	Hrtrt18	Heart rate QTL 18			heart pumping trait (VT:2000009)	heart rate (CMO:0000002)	2	157142078	192625452	Rat
2301966	Bp322	Blood pressure QTL 322	3.58		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	150540301	202447032	Rat
1298083	Bp158	Blood pressure QTL 158	2.62		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	189020722	215287351	Rat
1298080	Bp163	Blood pressure QTL 163		0.02	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	66118275	202447032	Rat
8662832	Vetf7	Vascular elastic tissue fragility QTL 7	3.5		aorta elastin amount (VT:0003905)	aorta wall extracellular elastin dry weight to aorta wall dry weight ratio (CMO:0002002)	2	81689826	221035911	Rat
1331745	Bp203	Blood pressure QTL 203	4.377		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	2	189599258	218414891	Rat
1298085	Bp165	Blood pressure QTL 165		0.0006	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	42804607	202447032	Rat
8694194	Abfw1	Abdominal fat weight QTL 1	11.7	0.001	visceral adipose mass (VT:0010063)	abdominal fat pad weight to body weight ratio (CMO:0000095)	2	182171407	227171407	Rat
61366	Iddm3	Insulin dependent diabetes mellitus QTL 3	4.7		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	2	189599258	234599258	Rat
1359022	Ppulsi1	Prepulse inhibition QTL 1	3.63		prepulse inhibition trait (VT:0003088)	acoustic startle response measurement (CMO:0001519)	2	136916935	213594495	Rat
1641891	Alcrsp17	Alcohol response QTL 17			response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	2	149559561	249053267	Rat
724534	Uae6	Urinary albumin excretion QTL 6	10		urine albumin amount (VT:0002871)	urine albumin level (CMO:0000130)	2	78665619	249053267	Rat
61374	Edpm2	Estrogen-dependent pituitary mass QTL 2	4.42	0.86	pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	2	76539322	202447032	Rat
2300189	Bmd48	Bone mineral density QTL 48	5.8	0.0001	femur mineral mass (VT:0010011)	volumetric bone mineral density (CMO:0001553)	2	179335906	224335906	Rat
8662843	Vetf9	Vascular elastic tissue fragility QTL 9	2.05		thoracic aorta molecular composition trait (VT:0010568)	aorta wall extracellular elastin dry weight to aorta wall extracellular collagen weight ratio (CMO:0002003)	2	157142078	226277316	Rat
2301408	Kidm36	Kidney mass QTL 36		0.002	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	2	190613715	226808892	Rat
631501	Bp101	Blood pressure QTL 101	2.4		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	150341684	202446871	Rat
2307174	Activ3	Activity QTL 3	4.83	0.000058	locomotor behavior trait (VT:0001392)	number of entries into a discrete space in an experimental apparatus (CMO:0000960)	2	168594495	213594495	Rat
1331794	Bp202	Blood pressure QTL 202	3.66819		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	141194931	223265385	Rat
71113	Cari2	Carrageenan-induced inflammation QTL 2	2.7	0.009	hypodermis integrity trait (VT:0010550)	inflammatory exudate volume (CMO:0001429)	2	141596551	202447032	Rat
1331805	Cm29	Cardiac mass QTL 29	3.50746		heart mass (VT:0007028)	heart wet weight (CMO:0000069)	2	141194931	223265385	Rat
634308	Sach6	Saccharin preference QTL 6	4.9		taste sensitivity trait (VT:0001986)	saccharin intake volume to total fluid intake volume ratio (CMO:0001601)	2	112456140	212696837	Rat
1358917	Cm42	Cardiac mass QTL 42	2.82		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	2	25413423	203928301	Rat
724568	Uae13	Urinary albumin excretion QTL 13	4.4		urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	2	143157029	210020885	Rat
7488929	Bp366	Blood pressure QTL 366		0.001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	2	184974550	193094998	Rat
1358913	Cm41	Cardiac mass QTL 41	2.73		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	2	25413423	203928301	Rat
1300165	Rf9	Renal function QTL 9	3.28		kidney glomerulus integrity trait (VT:0010546)	index of glomerular damage (CMO:0001135)	2	133914684	202447032	Rat
738013	Alc15	Alcohol consumption QTL 15	4.1	0.00022	consumption behavior trait (VT:0002069)	ethanol drink intake rate to body weight ratio (CMO:0001616)	2	184165752	229165752	Rat
61398	Bp50	Blood pressure QTL 50	4.4		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	189599258	234599258	Rat
631507	Bp105	Blood pressure QTL 105		0.001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	2	112456140	212696837	Rat
1641925	Alcrsp2	Alcohol response QTL 2			response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	2	149559561	221167075	Rat
1354609	Niddm62	Non-insulin dependent diabetes mellitus QTL 62	4.72	0.000006	insulin secretion trait (VT:0003564)	plasma insulin level (CMO:0000342)	2	150540301	202447032	Rat
1598833	Bp295	Blood pressure QTL 295	3.5		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	147798556	192798556	Rat
61417	Cia10	Collagen induced arthritis QTL 10	3.4		joint integrity trait (VT:0010548)	experimental arthritis severity measurement (CMO:0001459)	2	179946951	224946951	Rat
1354622	Kidm16	Kidney mass QTL 16	3		kidney mass (VT:0002707)	left kidney wet weight (CMO:0000083)	2	81754530	222436696	Rat
631266	Bp132	Blood pressure QTL 132		0.0005	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	46123260	202447032	Rat
8694383	Bw158	Body weight QTL 158	7.69	0.001	body lean mass (VT:0010483)	lean tissue morphological measurement (CMO:0002184)	2	182171407	227171407	Rat
7488927	Bp365	Blood pressure QTL 365		0.008	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	2	162765032	207765032	Rat
1598838	Bp290	Blood pressure QTL 290	1.9		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	166539266	211539266	Rat
7488925	Bp364	Blood pressure QTL 364		0.001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	2	160564068	205564068	Rat
2306901	Bp337	Blood pressure QTL 337		0.01	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	164073756	227146641	Rat
1354605	Rf48	Renal function QTL 48	2.9		blood creatinine amount (VT:0005328)	plasma creatinine level (CMO:0000537)	2	74786664	206665859	Rat
2293084	Iddm26	Insulin dependent diabetes mellitus QTL 26	2.9		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	2	174930955	213594495	Rat

RH133747

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	2	191,309,976 - 191,310,126 (+)	MAPPER	mRatBN7.2
Rnor_6.0	2	206,285,153 - 206,285,302	NCBI	Rnor6.0
Rnor_5.0	2	225,708,863 - 225,709,012	UniSTS	Rnor5.0
RGSC_v3.4	2	199,025,784 - 199,025,933	UniSTS	RGSC3.4
Celera	2	183,781,735 - 183,781,884	UniSTS
RH 3.4 Map	2	1327.9	UniSTS
Cytogenetic Map	2	q34	UniSTS

AA957141

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	2	191,311,825 - 191,312,073 (+)	MAPPER	mRatBN7.2
Rnor_6.0	2	206,287,002 - 206,287,249	NCBI	Rnor6.0
Rnor_5.0	2	225,710,712 - 225,710,959	UniSTS	Rnor5.0
RGSC_v3.4	2	199,027,633 - 199,027,880	UniSTS	RGSC3.4
Celera	2	183,783,584 - 183,783,831	UniSTS
RH 3.4 Map	2	1323.7	UniSTS
Cytogenetic Map	2	q34	UniSTS

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	renal system	reproductive system	respiratory system
9	11	49	113	91	90	59	25	59	6	218	97	93	45	60	31


RefSeq Transcripts	NM_001025687	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001389222	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006233078	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006233079	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006233080	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039102403	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039102405	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039102406	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	BC098939	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH474015	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000002	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000026213 ⟹ ENSRNOP00000026213

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	2	191,309,913 - 191,318,423 (-)	Ensembl
Rnor_6.0 Ensembl	2	206,285,089 - 206,293,599 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000080702 ⟹ ENSRNOP00000072954

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	2	191,316,299 - 191,318,423 (-)	Ensembl
Rnor_6.0 Ensembl	2	206,287,245 - 206,293,275 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000115006 ⟹ ENSRNOP00000086363

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	2	191,309,913 - 191,318,367 (-)	Ensembl

RefSeq Acc Id:

NM_001025687 ⟹ NP_001020858

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	2	193,998,350 - 194,006,840 (-)	NCBI
mRatBN7.2	2	191,309,909 - 191,318,399 (-)	NCBI
Rnor_6.0	2	206,285,087 - 206,293,599 (-)	NCBI
Rnor_5.0	2	225,708,795 - 225,717,309 (-)	NCBI
RGSC_v3.4	2	199,025,718 - 199,034,230 (-)	RGD
Celera	2	183,781,669 - 183,790,181 (-)	RGD

Sequence:

show sequence

CGGAAATCAGCTACTAGAGTCTGTCTCCCCGCCGCCGCGCGCGCTTTGACAAAGTTGCGGACTGGGCCTAAGCTCCCGCGCACGGGTGGCTTCTGGCCTTGTTCTTGAATCCACATGTCGTTGGGACG
CTGTCGTGGAAGCCTCACCCAGGAGTGCAGTTCCCGCGAAGACCCCACTGGGTGACTCCTCAACTCTGCCACCATGAACGGGGTCGTAATCCCCCAAACACCCATCGCTGTGGATTTTTGGAGCCTGC
GCCGTGCTGGTACCGCGCGGCTCTTCTTCTTATCCCACATGCACTGTGACCACACGGTGGGCCTGTCTAGCACTTGGGCACGGCCCCTCTACTGCTCTCCCATCACTGCCCACCTCTTGCATCGTCGC
CTGCAGGTGTCTAAGCAGTGGATCCGAGCTCTGGAGATTGGTGAGAGCCATGTATTACTTCTAGATGAAATTGGACAAGAAACCATGACTGTAACCCTCATAGATGCCAATCACTGTCCTGGTTCTGT
CATGTTTCTCTTTGAAGGATACTTTGGAACAATTCTCTACACAGGTGATTTTCGATATACACCGTCCATGCTGAAGGAGCCTGCTCTGACACTAGGGAAACAGATTCATACTTTATATCTAGACAACA
CCAATTGCAACCCAGCCCTTGTTCTTCCTTCCCGACAGGAAGCTACTCAACAGATTATCCAGCTAATCCGACAGTTCCCCCAACACAACATAAAGATTGGCCTCTATAGTCTAGGAAAAGAATCACTG
CTGGAGCAGCTAGCCCTTGAGTTTCAGACCTGGGTGGTATTGAGTCCTCAACGCCTGGAGTTGGTACAGCTGCTGGGCCTGGCAGACGTGTTCACAGTGGAGGAAGAAGCTGGGCGAATCCACGCTGT
GGACCACATGGAAATCTGCCATTCGGCCATGCTTCAGTGGAACCAGACCCACCCCACCATTGCTATTTTCCCCACAAGCCGGAAAATACGAAGCCCTCACCCCAGCATCTACAGCATCCCTTACTCTG
ACCATTCATCCTACTCTGAGCTTCGAGCATTTGTTGCAGCTCTGAGGCCTTGCCAGGTGGTGCCCATAGTCCGTGAACAGCCTTGTGGAGAGTTTTTTTCAGGATAGCTTGAGTCCTAGACTCTCTAT
GCCTCTGATTCCACACTCTGTGCAACAATACATGAGTTCCTCCTCGAGGAAAACAAATGTGTTTTGGCAGTTAGAAAGGAGGCTAAAGAGGCCAAGAACCCAGGGTGTTGTGTTTGAATCCCCTGAGG
AGAAAGCTGATCAGGTTAAAGTTGACAGAGACTCAAAGAAACACAAAAAAGAAAGCCTCTCCCCCTGGGCTGGGTGCCTTTCGAGGCTTTGCCCCCATCCTCTGCAGGCCAGGAAGCAGTTGTTCCCA
GATTTCTGCAGAAAAGAAGGTGATGAGCCAGTTCTTTTCTGTGACTCCAACAAGATGGCGACTGTGTTGACTGCCCCATTGGAACTTTCAGTGCAGTTACAGCCTGTAGATGAGTTTCCCTTTCCAGA
AACCAGGGAGGAAATTGGCTTAGGGTCCCCATTGTGGTCAGGGGGAGGCAGTGGCTCACCAACGAGAGGGAAGCAAAGCAATGGCATGGGCTGTGGTTCTCCCCCAACTCACATTAGCAGAACCACTC
ATCTAACTCCTGAGTCCGGGGGCCTGGCGTTAAAATACCTTCTTACTCCAGTGGATTTCCTCCAAGCAGGGTTCTCCTCCAGGAACTTTGACCAGCAAGTGGAAAAACACCAGAGAGTGCAGTGTAAC
AATCCTGCAGTTATGAACACAGTGGATGATGTCTAGTGGCAAGAGTTGGCTTGGTGTCTTCCTTTACAGAATCCTGTGGCTCACTCTGAGTGGCTCTTCTAAAGCTTTTTATGAAGTCCTGGTGCCTA
AGAAACCCTTAGTTTTATAGTACATTTATTGCTTAATTTTATTATATTTAAGAAACAGTTTTCATTATATAAACTATTCAGTGTTCATAAGCACATTGAAAGTTCTTAGAAGTTCCATAGCAATTTAA
TTTGTTCCACTTGGTTTAACCCAGTTTTTCTCAACCCTTTATCAGCATCAAGTTTGTTTGTTTTTTTGTTTTGTTAGAGTCTGAATCAAAAAGAATCAGGCTTGTCCCGTTGTCATTTCCTTTGTTAT
ATCCCAGTCCCCAAGTTCCCATCACCCTTTTTCCAGATAAAAGTCTACATTATTTATTTTCAGACTGTAATTTATAGTGCTGGAGGATAAAGTGGGGGTGCAGAGCAGCATGTTCTAACCCTGACTGT
CACTGACTCGCTGTGACATGACCCTACCCAAGTAACTTCCTGTCTCTGCCTCTTGGAGTGAACAGGAAACCATGAAAAGGCATTGAAACAGTGTTAGGAAAATAACACCTTCCTCCTGCGTGAAGGGG
TTTAGTAACTGTCATGAGACCTCCATCTGGAACATAGCCGTTTGGAGGTTAGACACCACGCACCATGGTGGCGCATGGGACAAGCTGAACATTAAGGTTTAGAACATGTCAGTGCTACTGGATGCTTG
CAGACACTGCTTTGTTAAAGCTACAGAAGATCAAATGTGCTGCCAGATATCCTCTGATGGTTCACATAGCTGGGATTTTCCCCCCCACCCCCACAAGTTTGAATTAGGGAGCCAGAGCACAGAGCTTG
TTTGTTTTAGTATCCAGGGGAGAGAGACCAAGGAGCCAGCTGGCTGGAACGGGTCAGAGTATGCAGTTCTACCCTGCCCTGCTCATAACCTGACAAAATGCCAAACCAATAAGCAAGACAGCTGATAG
CAGAGCCATGAGGAAATGTGCTCTGGGAGGGTGCAGGCAAGGAGCAGCTTAGGCCTGGAACCATGAGCAGTAACAATAAAGAAAGTCGCCTCACCCTTGGGAAGGAGGGAGGAGCTCTGCTACTTTGG
GAGGGAGAAGTGGAGTTTATTGAGCAAAATAAGACTTTGCTCTCGGACACACTGTACTCAGTTCTGTTTTTGTCAGTGACCTTCCTATAAACCTCTAAGGGCTTCATAGGAACTGCAGCAGGTGAGGC
ATGTGGTTCAACAGGAAACCTAGACATTGGCTGGAATCCAGGGCACATGGCAAATTGTTTGAATAGATGAGCCTTACTCAGCTGCAATGTGGGGGCTGAGATATCTACCTCCCATGATTGCTATGCAG
ACTATTGGTAAAATTCCCTAGCTCATTGCCTGGCACATGACAGTATTTCAAATATTGGTTTTCGTAGCTAAAAGTCTAGCTCTGGTAGGATGGGTGCTTAGCAAACTGAAATTCTGGATTCTATCCTG
AGTGCCAAAAAAAGAGGCAATCTTCAAAACAATTTTCTATGAAAACACAAAGTTAAATGTTTTCCACGTAGACTAGTTGATGGGCATTTTTCTAGTCTTTCTGAGGATATGTGTAAAATCTGTACATT
TTCAGAAGTAGGATATTTCACACATGTGCACACACACAAAGGGTGCAGAACAGATGGCCAAGTGGTTAAGAGCTCTTAATGTGCTGCTCTTGAAGACCTGACTTTGGTTCCCAGCACCTTCATTGGGT
TGATCATAACTCAAGTTCCAGGGGTCTTTCACCTTCTGACCTCTGTGAATAACTGCACAAAAACTTGTATGGTCTCACACAATACACATAAATAAAAATTTTTAAATAATGTTTTGAAGGGGGCCAGG
GAGATGGCTCAGTGGGTAAAAGCACTTGTCACACAAACTGGTGAACTAGATTCAATCCCCAGAACCCACATAAAAGTGAAGGAGAACTGAGTCAATAAAGCTGTCCTCCAGCTGGTTGCCATGCTTGC
CTATGAACAATACTAAAAGGGGGGCCATAAGATAACACTGTATATGATTCCTTAATTCCTTAATTGGAACTCAAAGTGCCATTATAAAAAATGCTTTGTTAATAGGATGTAACTACATGTTAATAAAT
CATTCTCATATTATTCAAAAAAAAAAAAAAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

NM_001389222 ⟹ NP_001376151

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	2	193,998,350 - 194,006,840 (-)	NCBI
mRatBN7.2	2	191,309,909 - 191,318,399 (-)	NCBI

RefSeq Acc Id:

XM_006233080 ⟹ XP_006233142

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	2	193,998,352 - 194,006,873 (-)	NCBI
mRatBN7.2	2	191,309,909 - 191,318,137 (-)	NCBI
Rnor_6.0	2	206,285,085 - 206,293,564 (-)	NCBI
Rnor_5.0	2	225,708,795 - 225,717,309 (-)	NCBI

Sequence:

show sequence

CGCGCGCGCTTTGACAAAGTTGCGGACTGGGCCTAAGCTCCCGCGCACGGGTGTGAGTAATGCT
CTCCGGGCTTCTTCCGCGTTGGGCGCTTCCACCCTGGCTGTCCCGAGCGCGGCCACCCTCTTTTTCTTCACCCTGTCTACTTCTTCCATTTCTGGGATGGTTTTCCTTTAGGGCTTCTGGCCTTGTTC
TTGAATCCACATGTCGTTGGGACGCTGTCGTGGAAGCCTCACCCAGGAGTGCAGTTCCCGCGAAGACCCCACTGGGTGACTCCTCAACTCTGCCACCATGAACGGGGTCGTAATCCCCCAAACACCCA
TCGCTGTGGATTTTTGGAGCCTGCGCCGTGCTGGTACCGCGCGGCTCTTCTTCTTATCCCACATGCACTGTGACCACACGGTGGGCCTGTCTAGCACTTGGGCACGGCCCCTCTACTGCTCTCCCATC
ACTGCCCACCTCTTGCATCGTCGCCTGCAGGTGTCTAAGCAGTGGATCCGAGCTCTGGAGATTGGTGAGAGCCATGTATTACCTCTAGATGAAATTGGACAAGAAACCATGACTGTAACCCTCATAGA
TGCCAATCACTGTCCTGGTTCTGTCATGTTTCTCTTTGAAGGATACTTTGGAACAATTCTCTACACAGGCCTCTATAGTCTAGGAAAAGAATCACTGCTGGAGCAGCTAGCCCTTGAGTTTCAGACCT
GGGTGGTATTGAGTCCTCAACGCCTGGAGTTGGTACAGCTGCTGGGCCTGGCAGACGTGTTCACAGTGGAGGAAGAAGCTGGGCGAATCCACGCTGTGGACCACATGGAAATCTGCCATTCGGCCATG
CTTCAGTGGAACCAGACCCACCCCACCATTGCTATTTTCCCCACAAGCCGGAAAATACGAAGCCCTCACCCCAGCATCTACAGCATCCCTTACTCTGACCATTCATCCTACTCTGAGCTTCGAGCATT
TGTTGCAGCTCTGAGGCCTTGCCAGGTGGTGCCCATAGTCCGTGAACAGCCTTGTGGAGAGTTTTTTCAGGATAGCTTGAGTCCTAGACTCTCTATGCCTCTGATTCCACACTCTGTGCAACAATACA
TGAGTTCCTCCTCGAGGAAAACAAATGTGTTTTGGCAGTTAGAAAGGAGGCTAAAGAGGCCAAGAACCCAGGGTGTTGTGTTTGAATCCCCTGAGGAGAAAGCTGATCAGGTTAAAGTTGACAGAGAC
TCAAAGAAACACAAAAAAGAAAGCCTCTCCCCCTGGGCTGGGTGCCTTTCGAGGCTTTGCCCCCATCCTCTGCAGGCCAGGAAGCAGTTGTTCCCAGATTTCTGCAGAAAAGAAGGTGATGAGCCAGT
TCTTTTCTGTGACTCCAACAAGATGGCGACTGTGTTGACTGCCCCATTGGAACTTTCAGTGCAGTTACAGCCTGTAGATGAGTTTCCCTTTCCAGAAACCAGGGAGGAAATTGGCTTAGGGTCCCCAT
TGTGGTCAGGGGGAGGCAGTGGCTCACCAACGAGAGGGAAGCAAAGCAATGGCATGGGCTGTGGTTCTCCCCCAACTCACATTAGCAGAACCACTCATCTAACTCCTGAGTCCGGGGGCCTGGCGTTA
AAATACCTTCTTACTCCAGTGGATTTCCTCCAAGCAGGGTTCTCCTCCAGGAACTTTGACCAGCAAGTGGAAAAACACCAGAGAGTGCAGTGTAACAATCCTGCAGTTATGAACACAGTGGATGATGT
CTAGTGGCAAGAGTTGGCTTGGTGTCTTCCTTTACAGAATCCTGTGGCTCACTCTGAGTGGCTCTTCTAAAGCTTTTTATGAAGTCCTGGTGCCTAAGAAACCCTTAGTTTTATAGTACATTTATTGC
TTAATTTTATTATATTTAAGAAACAGTTTTCATTATATAAACTATTCAGTGTTCATAAGCACATTGAAAGTTCTTAGAAGTTCCATAGCAATTTAATTTGTTCCACTTGGTTTAACCCAGTTTTTCTC
AACCCTTTATCAGCATCAAGTTTGTTTGTTTTTTTGTTTTGTTAGAGTCTGAATCAAAAAGAATCAGGCTTGTCCCGTTGTCATTTCCTTTGTTATATCCCAGTCCCCAAGTTCCCATCACCCTTTTT
CCAGATAAAAGTCTACATTATTTATTTTCAGACTGTAATTTATAGTGCTGGAGGATAAAGTGGGGGTGCAGAGCAGCATGTTCTAACCCTGACTGTCACTGACTCGCTGTGACATGACCCTACCCAAG
TAACTTCCTGTCTCTGCCTCTTGGAGTGAACAGGAAACCATGAAAAGGCATTGAAACAGTGTTAGGAAAATAACACCTTCCTCCTGCGTGAAGGGGTTTAGTAACTGTCATGAGACCTCCATCTGGAA
CATAGCCGTTTGGAGGTTAGACACCACGCACCATGGTGGCGCATGGGACAAGCTGAACATTAAGGTTTAGAACATGTCAGTGCTACTGGATGCTTGCAGACACTGCTTTGTTAAAGCTACAGAAGATC
AAATGTGCTGCCAGATATCCTCTGATGGTTCACATAGCTGGGATTTTCCCCCCCACCCCCACAAGTTTGAATTAGGGAGCCAGAGCACAGAGCTTGTTTGTTTTAGTATCCAGGGGAGAGAGACCAAG
GAGCCAGCTGGCTGGAACGGGTCAGAGTATGCAGTTCTACCCTGCCCTGCTCATAACCTGACAAAATGCCAAACCAATAAGCAAGACAGCTGATAGCAGAGCCATGAGGAAATGTGCTCTGGGAGGGT
GCAGGCAAGGAGCAGCTTAGGCCTGGAACCATGAGCAGTAACAATAAAGAAAGTCGCCTCACCCTTGGGAAGGAGGGAGGAGCTCTGCTACTTTGGGAGGGAGAAGTGGAGTTTATTGAGCAAAATAA
GACTTTGCTCTCGGACACACTGTACTCAGTTCTGTTTTTGTCAGTGACCTTCCTATAAACCTCTAAGGGCTTCATAGGAACTGCAGCAGGTGAGGCATGTGGTTCAACAGGAAACCTAGACATTGGCT
GGAATCCAGGGCACATGGCAAATTGTTTGAATAGATGAGCCTTACTCAGCTGCAATGTGGGGGCTGAGATATCTACCTCCCATGATTGCTATGCAGACTATTGGTAAAATTCCCTAGCTCATTGCCTG
GCACATGACAGTATTTCAAATATTGGTTTTCGTAGCTAAAAGTCTAGCTCTGGTAGGATGGGTGCTTAGCAAACTGAAATTCTGGATTCTATCCTGAGTGCCAAAAAAAGAGGCAATCTTCAAAACAA
TTTTCTATGAAAACACAAAGTTAAATGTTTTCCACGTAGACTAGTTGATGGGCATTTTTCTAGTCTTTCTGAGGATATGTGTAAAATCTGTACATTTTCAGAAGTAGGATATTTCACACATGTGCACA
CACACAAAGGGTGCAGAACAGATGGCCAAGTGGTTAAGAGCTCTTAATGTGCTGCTCTTGAAGACCTGACTTTGGTTCCCAGCACCTTCATTGGGTTGATCATAACTCAAGTTCCAGGGGTCTTTCAC
CTTCTGACCTCTGTGAATAACTGCACAAAAACTTGTATGGTCTCACACAATACACATAAATAAAAATTTTTAAATAATGTTTTGAAGGGGGCCAGGGAGATGGCTCAGTGGGTAAAAGCACTTGTCAC
ACAAACTGGTGAACTAGATTCAATCCCCAGAACCCACATAAAAGTGAAGGAGAACTGAGTCAATAAAGCTGTCCTCCAGCTGGTTGCCATGCTTGCCTATGAACAATACTAAAAGGGGGGCCATAAGA
TAACACTGTATATGATTCCTTAATTCCTTAATTGGAACTCAAAGTGCCATTATAAAAAATGCTTTGTTAATAGGATGTAACTACATGTTAATAAATCATTCTCATATTATTCAACA

hide sequence

RefSeq Acc Id:

XM_039102403 ⟹ XP_038958331

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	2	193,998,352 - 194,005,632 (-)	NCBI
mRatBN7.2	2	191,309,909 - 191,317,191 (-)	NCBI

RefSeq Acc Id:

XM_039102405 ⟹ XP_038958333

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	2	194,001,699 - 194,006,851 (-)	NCBI
mRatBN7.2	2	191,313,258 - 191,318,137 (-)	NCBI

RefSeq Acc Id:

XM_039102406 ⟹ XP_038958334

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	2	194,001,699 - 194,006,846 (-)	NCBI
mRatBN7.2	2	191,313,258 - 191,318,137 (-)	NCBI


Protein RefSeqs	NP_001020858	(Get FASTA)	NCBI Sequence Viewer
	NP_001376151	(Get FASTA)	NCBI Sequence Viewer
	XP_006233142	(Get FASTA)	NCBI Sequence Viewer
	XP_038958331	(Get FASTA)	NCBI Sequence Viewer
	XP_038958333	(Get FASTA)	NCBI Sequence Viewer
	XP_038958334	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH98939	(Get FASTA)	NCBI Sequence Viewer
	EDL85472	(Get FASTA)	NCBI Sequence Viewer
	EDL85473	(Get FASTA)	NCBI Sequence Viewer
	EDL85474	(Get FASTA)	NCBI Sequence Viewer
	EDL85475	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000026213.7
	ENSRNOP00000072954.2
	ENSRNOP00000086363.1
GenBank Protein	Q4KLY6	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_001020858 ⟸ NM_001025687

- UniProtKB:

Q4KLY6 (UniProtKB/Swiss-Prot), G3V8I3 (UniProtKB/TrEMBL), A6K3M4 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MNGVVIPQTPIAVDFWSLRRAGTARLFFLSHMHCDHTVGLSSTWARPLYCSPITAHLLHRRLQVSKQWIRALEIGESHVLLLDEIGQETMTVTLIDANHCPGSVMFLFEGYFGTILYTGDFRYTPSML
KEPALTLGKQIHTLYLDNTNCNPALVLPSRQEATQQIIQLIRQFPQHNIKIGLYSLGKESLLEQLALEFQTWVVLSPQRLELVQLLGLADVFTVEEEAGRIHAVDHMEICHSAMLQWNQTHPTIAIFP
TSRKIRSPHPSIYSIPYSDHSSYSELRAFVAALRPCQVVPIVREQPCGEFFSG

hide sequence

RefSeq Acc Id:	XP_006233142 ⟸ XM_006233080
- Peptide Label:	isoform X1
- UniProtKB:	Q4KLY6 (UniProtKB/Swiss-Prot)
- Sequence:	show sequence MNGVVIPQTPIAVDFWSLRRAGTARLFFLSHMHCDHTVGLSSTWARPLYCSPITAHLLHRRLQV SKQWIRALEIGESHVLPLDEIGQETMTVTLIDANHCPGSVMFLFEGYFGTILYTGLYSLGKESLLEQLALEFQTWVVLSPQRLELVQLLGLADVFTVEEEAGRIHAVDHMEICHSAMLQWNQTHPTIA IFPTSRKIRSPHPSIYSIPYSDHSSYSELRAFVAALRPCQVVPIVREQPCGEFFQDSLSPRLSMPLIPHSVQQYMSSSSRKTNVFWQLERRLKRPRTQGVVFESPEEKADQVKVDRDSKKHKKESLSP WAGCLSRLCPHPLQARKQLFPDFCRKEGDEPVLFCDSNKMATVLTAPLELSVQLQPVDEFPFPETREEIGLGSPLWSGGGSGSPTRGKQSNGMGCGSPPTHISRTTHLTPESGGLALKYLLTPVDFLQ AGFSSRNFDQQVEKHQRVQCNNPAVMNTVDDV hide sequence

Ensembl Acc Id:

ENSRNOP00000072954 ⟸ ENSRNOT00000080702

Ensembl Acc Id:

ENSRNOP00000026213 ⟸ ENSRNOT00000026213

RefSeq Acc Id:	NP_001376151 ⟸ NM_001389222
- UniProtKB:	Q4KLY6 (UniProtKB/Swiss-Prot), G3V8I3 (UniProtKB/TrEMBL), A6K3M4 (UniProtKB/TrEMBL)

Protein Domains

DNA repair metallo-beta-lactamase Metallo-beta-lactamase

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q4KLY6-F1-model_v2	AlphaFold	Q4KLY6	1-541	view protein structure

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

RGD ID:

13691630

Promoter ID:

EPDNEW_R2155

Type:

initiation region

Name:

Dclre1b_1

Description:

DNA cross-link repair 1B

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	2	206,293,506 - 206,293,566	EPDNEW

Database	Acc Id	Source(s)
BioCyc Gene	G2FUF-51794	BioCyc
Ensembl Genes	ENSRNOG00000019367	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000026213.7	UniProtKB/TrEMBL
	ENSRNOT00000080702.2	UniProtKB/TrEMBL
	ENSRNOT00000115006.1	UniProtKB/TrEMBL
Gene3D-CATH	3.40.50.12650	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	3.60.15.10	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE	IMAGE:7455348	IMAGE-MGC_LOAD
InterPro	DRMBL	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Metallo-B-lactamas	UniProtKB/TrEMBL
	RibonucZ/Hydroxyglut_hydro	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	rno:310745	UniProtKB/Swiss-Prot
MGC_CLONE	MGC:114481	IMAGE-MGC_LOAD
NCBI Gene	310745	ENTREZGENE
PANTHER	5' EXONUCLEASE APOLLO	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	DNA CROSS-LINK REPAIR PROTEIN PSO2/SNM1-RELATED	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam	DRMBL	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Lactamase_B_2	UniProtKB/TrEMBL
PharmGKB	DCLRE1B	RGD
PhenoGen	Dclre1b	PhenoGen
RatGTEx	ENSRNOG00000019367	RatGTEx
Superfamily-SCOP	SSF56281	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt	A0A0G2K494	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I6A125_RAT	UniProtKB/TrEMBL
	A6K3M4	ENTREZGENE, UniProtKB/TrEMBL
	A6K3M5	ENTREZGENE, UniProtKB/TrEMBL
	A6K3M8_RAT	UniProtKB/TrEMBL
	DCR1B_RAT	UniProtKB/Swiss-Prot
	G3V8I3	ENTREZGENE, UniProtKB/TrEMBL
	Q4KLY6	ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2011-08-02	Dclre1b	DNA cross-link repair 1B	Dclre1b	DNA cross-link repair 1B, PSO2 homolog (S. cerevisiae)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2005-12-06	Dclre1b	DNA cross-link repair 1B, PSO2 homolog (S. cerevisiae)	Dclre1b_predicted	DNA cross-link repair 1B, PSO2 homolog (S. cerevisiae) (predicted)	Symbol and Name updated	1559027	APPROVED
2005-01-12	Dclre1b_predicted	DNA cross-link repair 1B, PSO2 homolog (S. cerevisiae) (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailable


InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailable


Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
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MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable

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