Mzb1 (marginal zone B and B1 cell-specific protein) - Rat Genome Database

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Gene: Mzb1 (marginal zone B and B1 cell-specific protein) Rattus norvegicus
Analyze
Symbol: Mzb1
Name: marginal zone B and B1 cell-specific protein
RGD ID: 1310251
Description: Predicted to be involved in several processes, including integrin activation; positive regulation of immunoglobulin production; and regulation of B cell proliferation. Predicted to be located in endoplasmic reticulum lumen. Predicted to be part of endoplasmic reticulum chaperone complex. Predicted to be active in extracellular region. Orthologous to human MZB1 (marginal zone B and B1 cell specific protein); INTERACTS WITH 17beta-estradiol; 17beta-estradiol 3-benzoate; alpha-Zearalanol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: LOC291675; marginal zone B- and B1-cell-specific protein; MGC112758; PACAP; pERp1; plasma cell-induced resident endoplasmic reticulum protein; plasma cell-induced resident ER protein; proapoptotic caspase adapter protein; RGD1310251; similar to RIKEN cDNA 2010001M09
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81827,513,087 - 27,515,148 (-)NCBIGRCr8
mRatBN7.21827,238,999 - 27,241,060 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1827,239,001 - 27,241,094 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1827,366,417 - 27,368,478 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01828,128,528 - 28,130,589 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01827,463,414 - 27,465,475 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01828,436,546 - 28,438,607 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1828,436,548 - 28,438,654 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01828,149,656 - 28,151,717 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41828,261,741 - 28,263,802 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11828,288,388 - 28,290,448 (-)NCBI
Celera1826,972,541 - 26,974,602 (-)NCBICelera
Cytogenetic Map18p11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model



  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Mzb1RatCOVID-19  ISOMZB1 (Homo sapiens)9068941mRNA:increased expression:peripheral blood mononuclear cell (human)RGDPMID:32228226 and REF_RGD_ID:28912744
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Mzb1Ratautosomal dominant intellectual developmental disorder 31  ISOMZB1 (Homo sapiens)8554872ClinVar Annotator: match by term: NEURODEVELOPMENTAL DISORDER WITH NEONATAL RESPIRATORY INSUFFICIENCY more ...ClinVarPMID:28492532
Mzb1Ratfamilial adenomatous polyposis 1  ISOMZB1 (Homo sapiens)8554872ClinVar Annotator: match by term: Familial adenomatous polyposis 1ClinVarPMID:17963004 more ...
Mzb1RatHereditary Neoplastic Syndromes  ISOMZB1 (Homo sapiens)8554872ClinVar Annotator: match by term: Hereditary cancer-predisposing syndromeClinVarPMID:17963004 more ...
Mzb1RatNeurodevelopmental Disorders  ISOMZB1 (Homo sapiens)8554872ClinVar Annotator: match by term: Neurodevelopmental disorderClinVarPMID:25741868
Mzb1RatSTING-associated vasculopathy with onset in infancy  ISOMZB1 (Homo sapiens)8554872ClinVar Annotator: match by term: STING-associated vasculopathy with onset in infancyClinVarPMID:28492532

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Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Mzb1Rat(-)-demecolcine decreases expressionISOMZB1 (Homo sapiens)6480464Demecolcine results in decreased expression of MZB1 mRNACTDPMID:23649840
Mzb1Rat17beta-estradiol multiple interactionsEXP 6480464[estradiol 3-benzoate co-treated with [Testosterone co-treated with Estradiol]] results in increased expression of MZB1 mRNACTDPMID:32741896
Mzb1Rat17beta-estradiol 3-benzoate multiple interactionsEXP 6480464[estradiol 3-benzoate co-treated with [Testosterone co-treated with Estradiol]] results in increased expression of MZB1 mRNACTDPMID:32741896
Mzb1Rat2,4-dibromophenyl 2,4,5-tribromophenyl ether affects expressionISOMzb1 (Mus musculus)64804642 more ...CTDPMID:38648751
Mzb1Rat4,4'-sulfonyldiphenol decreases expressionISOMzb1 (Mus musculus)6480464bisphenol S results in decreased expression of MZB1 mRNACTDPMID:39298647
Mzb1Ratalpha-Zearalanol increases expressionEXP 6480464Zeranol results in increased expression of MZB1 mRNACTDPMID:35163327
Mzb1Ratbenzo[a]pyrene decreases methylationISOMZB1 (Homo sapiens)6480464Benzo(a)pyrene results in decreased methylation of MZB1 promoterCTDPMID:27901495
Mzb1Ratbis(2-ethylhexyl) phthalate decreases expressionISOMZB1 (Homo sapiens)6480464Diethylhexyl Phthalate results in decreased expression of MZB1 mRNACTDPMID:31163220
Mzb1Ratbisphenol A decreases expressionEXP 6480464bisphenol A results in decreased expression of MZB1 mRNACTDPMID:25181051
Mzb1Ratbisphenol A increases expressionISOMzb1 (Mus musculus)6480464bisphenol A results in increased expression of MZB1 mRNACTDPMID:32156529
Mzb1Ratbisphenol A decreases methylationISOMZB1 (Homo sapiens)6480464bisphenol A results in decreased methylation of MZB1 geneCTDPMID:31601247
Mzb1Ratbuta-1,3-diene decreases expressionISOMzb1 (Mus musculus)64804641 and 3-butadiene results in decreased expression of MZB1 mRNACTDPMID:29038090
Mzb1Ratcarbon nanotube affects expressionISOMzb1 (Mus musculus)6480464Nanotubes and Carbon affects the expression of MZB1 mRNACTDPMID:25554681
Mzb1Ratcarbon nanotube decreases expressionISOMzb1 (Mus musculus)6480464Nanotubes and Carbon analog results in decreased expression of MZB1 mRNACTDPMID:25554681
Mzb1Ratchlordecone increases expressionISOMzb1 (Mus musculus)6480464Chlordecone results in increased expression of MZB1 mRNACTDPMID:33711761
Mzb1Ratchloroprene decreases expressionISOMzb1 (Mus musculus)6480464Chloroprene results in decreased expression of MZB1 mRNACTDPMID:23125180
Mzb1Ratcisplatin decreases expressionISOMZB1 (Homo sapiens)6480464Cisplatin results in decreased expression of MZB1 mRNACTDPMID:27594783
Mzb1Ratdextran sulfate multiple interactionsISOMzb1 (Mus musculus)6480464evodiamine inhibits the reaction [Dextran Sulfate results in decreased expression of MZB1 protein]CTDPMID:35362542
Mzb1Ratdextran sulfate decreases expressionISOMzb1 (Mus musculus)6480464Dextran Sulfate results in decreased expression of MZB1 proteinCTDPMID:35362542
Mzb1Ratdimethylarsinic acid multiple interactionsISOMzb1 (Mus musculus)6480464[sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results in increased expression of MZB1 mRNACTDPMID:34876320

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Biological Process
1 to 20 of 21 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Mzb1Ratbiological_process  ND 159840702/2015: no relevant rat dataRGD 
Mzb1Ratintegrin activation involved_inISOMzb1 (Mus musculus)1624291 PMID:21093319RGDPMID:21093319
Mzb1Ratintegrin activation involved_inIEAUniProtKB:Q9D8I1 and ensembl:ENSMUSP000000252111600115GO_REF:0000107EnsemblGO_REF:0000107
Mzb1Ratintegrin activation involved_inISSUniProtKB:Q9D8I11600115GO_REF:0000024UniProtGO_REF:0000024
Mzb1Ratpositive regulation of cell population proliferation involved_inISSUniProtKB:Q9D8I11600115GO_REF:0000024UniProtGO_REF:0000024
Mzb1Ratpositive regulation of cell population proliferation involved_inIEAUniProtKB:Q9D8I1 and ensembl:ENSMUSP000000252111600115GO_REF:0000107EnsemblGO_REF:0000107
Mzb1Ratpositive regulation of cell population proliferation involved_inISOMzb1 (Mus musculus)1624291 PMID:21688198RGDPMID:21688198
Mzb1Ratpositive regulation of cell population proliferation involved_inISOMZB1 (Homo sapiens) and UniProtKB:Q8WU39-11624291 PMID:21688198RGDPMID:21688198
Mzb1Ratpositive regulation of immunoglobulin production involved_inISSUniProtKB:Q9D8I11600115GO_REF:0000024UniProtGO_REF:0000024
Mzb1Ratpositive regulation of immunoglobulin production involved_inIEAUniProtKB:Q9D8I1 and ensembl:ENSMUSP000000252111600115GO_REF:0000107EnsemblGO_REF:0000107
Mzb1Ratpositive regulation of immunoglobulin production involved_inISOMzb1 (Mus musculus)1624291 PMID:19805154 and PMID:19805157RGDPMID:19805154 and PMID:19805157
Mzb1Ratregulation of B cell proliferation involved_inISSUniProtKB:Q9D8I11600115GO_REF:0000024UniProtGO_REF:0000024
Mzb1Ratregulation of B cell proliferation involved_inIEAUniProtKB:Q9D8I1 and ensembl:ENSMUSP000000252111600115GO_REF:0000107EnsemblGO_REF:0000107
Mzb1Ratregulation of B cell proliferation involved_inISOMzb1 (Mus musculus)1624291 PMID:21093319RGDPMID:21093319
Mzb1Ratregulation of B cell proliferation involved_inIBAMGI:1917066 and PANTHER:PTN0010404901600115GO_REF:0000033GO_CentralGO_REF:0000033
Mzb1Ratregulation of cell population proliferation involved_inISSUniProtKB:Q9D8I11600115GO_REF:0000024UniProtGO_REF:0000024
Mzb1Ratregulation of cell population proliferation involved_inIEAUniProtKB:Q9D8I1 and ensembl:ENSMUSP000000252111600115GO_REF:0000107EnsemblGO_REF:0000107
Mzb1Ratregulation of cell population proliferation involved_inISOMzb1 (Mus musculus)1624291 PMID:21093319RGDPMID:21093319
Mzb1Ratregulation of insulin receptor signaling pathway involved_inISSUniProtKB:Q9D8I11600115GO_REF:0000024UniProtGO_REF:0000024
Mzb1Ratregulation of insulin receptor signaling pathway involved_inIEAUniProtKB:Q9D8I1 and ensembl:ENSMUSP000000252111600115GO_REF:0000107EnsemblGO_REF:0000107
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Cellular Component
1 to 17 of 17 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Mzb1Ratcytoplasm located_inISOMZB1 (Homo sapiens) and UniProtKB:Q8WU39-21624291 PMID:11350957RGDPMID:11350957
Mzb1Ratendoplasmic reticulum located_inIEAUniProtKB-KW:KW-02561600115GO_REF:0000043UniProtGO_REF:0000043
Mzb1Ratendoplasmic reticulum chaperone complex part_ofISOMzb1 (Mus musculus)1624291 PMID:19805157RGDPMID:19805157
Mzb1Ratendoplasmic reticulum chaperone complex part_ofIEAUniProtKB:Q9D8I1 and ensembl:ENSMUSP000000252111600115GO_REF:0000107EnsemblGO_REF:0000107
Mzb1Ratendoplasmic reticulum chaperone complex part_ofIBAMGI:1917066 and PANTHER:PTN0010404901600115GO_REF:0000033GO_CentralGO_REF:0000033
Mzb1Ratendoplasmic reticulum chaperone complex part_ofISSUniProtKB:Q9D8I11600115GO_REF:0000024UniProtGO_REF:0000024
Mzb1Ratendoplasmic reticulum lumen located_inISSUniProtKB:Q9D8I11600115GO_REF:0000024UniProtGO_REF:0000024
Mzb1Ratendoplasmic reticulum lumen located_inIEAUniProtKB:Q9D8I1 and ensembl:ENSMUSP000000252111600115GO_REF:0000107EnsemblGO_REF:0000107
Mzb1Ratendoplasmic reticulum lumen located_inISOMzb1 (Mus musculus)1624291 PMID:21093319RGDPMID:21093319
Mzb1Ratendoplasmic reticulum lumen located_inIEAUniProtKB-SubCell:SL-00961600115GO_REF:0000044UniProtGO_REF:0000044
Mzb1Ratextracellular region located_inISSUniProtKB:Q9D8I11600115GO_REF:0000024UniProtGO_REF:0000024
Mzb1Ratextracellular region located_inIEAUniProtKB-SubCell:SL-02431600115GO_REF:0000044UniProtGO_REF:0000044
Mzb1Ratextracellular region located_inIEAUniProtKB-KW:KW-09641600115GO_REF:0000043UniProtGO_REF:0000043
Mzb1Ratextracellular region is_active_inIBAMGI:1917066 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Mzb1Ratextracellular region located_inIEAUniProtKB:Q9D8I1 and ensembl:ENSMUSP000000252111600115GO_REF:0000107EnsemblGO_REF:0000107
Mzb1Ratextracellular region located_inISOMzb1 (Mus musculus)1624291 PMID:21688198RGDPMID:21688198
Mzb1Ratextracellular region located_inISOMZB1 (Homo sapiens) and UniProtKB:Q8WU39-11624291 PMID:21688198RGDPMID:21688198
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Molecular Function

  


#
Reference Title
Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
3. GOA pipeline RGD automated data pipeline
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
5. Comprehensive gene review and curation RGD comprehensive gene curation
PMID:11350957   PMID:12477932   PMID:19805154   PMID:19805157   PMID:20379803   PMID:20387008   PMID:20387010   PMID:20407844   PMID:20414744   PMID:20428965   PMID:20443077   PMID:20449688  
PMID:20449689   PMID:20461496   PMID:20567937   PMID:20692466   PMID:20699230   PMID:20703829   PMID:20728507   PMID:21093319   PMID:21688198  



Mzb1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81827,513,087 - 27,515,148 (-)NCBIGRCr8
mRatBN7.21827,238,999 - 27,241,060 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1827,239,001 - 27,241,094 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1827,366,417 - 27,368,478 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01828,128,528 - 28,130,589 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01827,463,414 - 27,465,475 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01828,436,546 - 28,438,607 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1828,436,548 - 28,438,654 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01828,149,656 - 28,151,717 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41828,261,741 - 28,263,802 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11828,288,388 - 28,290,448 (-)NCBI
Celera1826,972,541 - 26,974,602 (-)NCBICelera
Cytogenetic Map18p11NCBI
MZB1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh385139,387,467 - 139,389,913 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl5139,387,467 - 139,390,081 (-)EnsemblGRCh38hg38GRCh38
GRCh375138,723,156 - 138,725,602 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 365138,751,156 - 138,753,504 (-)NCBINCBI36Build 36hg18NCBI36
Cytogenetic Map5q31.2NCBI
HuRef5133,912,990 - 133,915,337 (-)NCBIHuRef
CHM1_15138,155,878 - 138,158,225 (-)NCBICHM1_1
T2T-CHM13v2.05139,913,564 - 139,916,009 (-)NCBIT2T-CHM13v2.0
Mzb1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391835,780,318 - 35,782,420 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1835,780,320 - 35,782,420 (-)EnsemblGRCm39 Ensembl
GRCm381835,647,265 - 35,650,266 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1835,647,267 - 35,649,367 (-)EnsemblGRCm38mm10GRCm38
MGSCv371835,806,919 - 35,809,021 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361835,773,246 - 35,775,341 (-)NCBIMGSCv36mm8
Celera1836,103,387 - 36,105,489 (-)NCBICelera
Cytogenetic Map18B2NCBI
cM Map1819.19NCBI
Mzb1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554181,170,365 - 1,172,581 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554181,170,365 - 1,172,581 (+)NCBIChiLan1.0ChiLan1.0
MZB1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v24134,654,445 - 134,668,804 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan15132,793,895 - 132,808,366 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v05134,758,631 - 134,772,992 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.15140,881,415 - 140,883,756 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl5140,881,415 - 140,883,756 (-)Ensemblpanpan1.1panPan2
MZB1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1234,710,487 - 34,712,660 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl234,706,007 - 34,712,626 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha231,812,781 - 31,814,951 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0235,164,568 - 35,166,738 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl235,164,553 - 35,166,707 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1232,217,016 - 32,219,186 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0233,083,316 - 33,085,486 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0233,834,939 - 33,837,109 (-)NCBIUU_Cfam_GSD_1.0
Mzb1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213153,134,080 - 153,136,601 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365318,474,954 - 8,476,936 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365318,474,721 - 8,477,479 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MZB1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl2141,277,544 - 141,279,641 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.12141,277,541 - 141,279,652 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.22147,108,147 - 147,110,263 (-)NCBISscrofa10.2Sscrofa10.2susScr3
MZB1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12342,059,984 - 42,062,700 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2342,060,290 - 42,062,334 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603435,825,018 - 35,827,881 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Mzb1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474332,192,251 - 32,194,376 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474332,192,264 - 32,194,848 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

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Variants in Mzb1
8 total Variants

Predicted Target Of
Summary Value
Count of predictions:38
Count of miRNA genes:34
Interacting mature miRNAs:38
Transcripts:ENSRNOT00000036301
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 33 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
1331733Bp233Blood pressure QTL 2333.97196arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)182479697779788953Rat
1358358Sradr6Stress Responsive Adrenal Weight QTL 62.49adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)181194429959330563Rat
1331735Rf44Renal function QTL 442.981urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)181823456431359530Rat
61382Bp46Blood pressure QTL 4618.8arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)181194179131393320Rat
2301413Bp318Blood pressure QTL 3180.002arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)182654808246969551Rat
1331741Bp232Blood pressure QTL 2323.59112arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)182137289383213037Rat
61388Bp2Blood pressure QTL 23.23arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)18135374722Rat
6903359Bp355Blood pressure QTL 3553.6arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)181194454459796478Rat
12904668Bw188Body weight QTL 1880.03body mass (VT:0001259)body weight (CMO:0000012)182654808246969551Rat
2313082Bss85Bone structure and strength QTL 850.80.0001long bone metaphysis morphology trait (VT:0000133)tibia midshaft total cross-sectional area (CMO:0001715)181495133759951337Rat

1 to 10 of 33 rows
RH131353  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21827,239,020 - 27,239,205 (+)MAPPERmRatBN7.2
Rnor_6.01828,436,568 - 28,436,752NCBIRnor6.0
Rnor_5.01828,149,678 - 28,149,862UniSTSRnor5.0
RGSC_v3.41828,261,763 - 28,261,947UniSTSRGSC3.4
Celera1826,972,563 - 26,972,747UniSTS
Cytogenetic Map18p11UniSTS




alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 104 91 90 59 25 59 6 218 97 84 45 59 31



Ensembl Acc Id: ENSRNOT00000036301   ⟹   ENSRNOP00000030810
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1827,239,001 - 27,241,094 (-)Ensembl
Rnor_6.0 Ensembl1828,436,548 - 28,438,654 (-)Ensembl
RefSeq Acc Id: NM_001024240   ⟹   NP_001019411
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81827,513,087 - 27,515,148 (-)NCBI
mRatBN7.21827,238,999 - 27,241,060 (-)NCBI
Rnor_6.01828,436,546 - 28,438,607 (-)NCBI
Rnor_5.01828,149,656 - 28,151,717 (-)NCBI
RGSC_v3.41828,261,741 - 28,263,802 (-)RGD
Celera1826,972,541 - 26,974,602 (-)RGD
Sequence:
Protein RefSeqs NP_001019411 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH93397 (Get FASTA)   NCBI Sequence Viewer  
  EDL76270 (Get FASTA)   NCBI Sequence Viewer  
  EDL76271 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000030810
  ENSRNOP00000030810.4
GenBank Protein Q561R0 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_001019411   ⟸   NM_001024240
- Peptide Label: precursor
- UniProtKB: Q561R0 (UniProtKB/Swiss-Prot),   A6J2Y9 (UniProtKB/TrEMBL),   A6J2Y8 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000030810   ⟸   ENSRNOT00000036301
DUF3456

Name Modeler Protein Id AA Range Protein Structure
AF-Q561R0-F1-model_v2 AlphaFold Q561R0 1-188 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

RGD ID:13700709
Promoter ID:EPDNEW_R11233
Type:multiple initiation site
Name:Mzb1_1
Description:marginal zone B and B1 cell-specific protein
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01828,438,641 - 28,438,701EPDNEW


1 to 19 of 19 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-7900 BioCyc
Ensembl Genes ENSRNOG00000022009 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000036301 ENTREZGENE
  ENSRNOT00000036301.7 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7389084 IMAGE-MGC_LOAD
InterPro DUF3456 UniProtKB/Swiss-Prot
  MZB1 UniProtKB/Swiss-Prot
KEGG Report rno:291675 UniProtKB/Swiss-Prot
MGC_CLONE MGC:112758 IMAGE-MGC_LOAD
NCBI Gene 291675 ENTREZGENE
PANTHER MARGINAL ZONE B- AND B1-CELL-SPECIFIC PROTEIN UniProtKB/Swiss-Prot
  MARGINAL ZONE B- AND B1-CELL-SPECIFIC PROTEIN UniProtKB/Swiss-Prot
Pfam DUF3456 UniProtKB/Swiss-Prot
PhenoGen Mzb1 PhenoGen
PROSITE ER_TARGET UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000022009 RatGTEx
UniProt A6J2Y8 ENTREZGENE, UniProtKB/TrEMBL
  A6J2Y9 ENTREZGENE, UniProtKB/TrEMBL
  MZB1_RAT UniProtKB/Swiss-Prot, ENTREZGENE
1 to 19 of 19 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2011-08-02 Mzb1  marginal zone B and B1 cell-specific protein  Pacap  proapoptotic caspase adapter protein  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2010-11-12 Pacap  proapoptotic caspase adapter protein  RGD1310251  similar to RIKEN cDNA 2010001M09  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-12-06 RGD1310251  similar to RIKEN cDNA 2010001M09  RGD1310251_predicted  similar to RIKEN cDNA 2010001M09 (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-20 RGD1310251_predicted  similar to RIKEN cDNA 2010001M09 (predicted)  LOC291675_predicted    Symbol and Name status set to approved 1331353 APPROVED
2005-01-12 LOC291675_predicted  similar to RIKEN cDNA 2010001M09 (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL