Ugp2 (UDP-glucose pyrophosphorylase 2) - Rat Genome Database

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Gene: Ugp2 (UDP-glucose pyrophosphorylase 2) Rattus norvegicus
Analyze
Symbol: Ugp2
Name: UDP-glucose pyrophosphorylase 2
RGD ID: 1310210
Description: Enables D-glucose binding activity; UTP:glucose-1-phosphate uridylyltransferase activity; and pyrimidine ribonucleotide binding activity. Involved in UDP-alpha-D-glucose metabolic process and glucose 1-phosphate metabolic process. Predicted to be active in cytoplasm. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 83. Orthologous to human UGP2 (UDP-glucose pyrophosphorylase 2); PARTICIPATES IN congenital sucrase-isomaltase deficiency pathway; galactokinase deficiency pathway; galactose metabolic pathway; INTERACTS WITH 17beta-estradiol; 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC289827; UTP--glucose-1-phosphate uridylyltransferase
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81499,657,637 - 99,698,573 (-)NCBIGRCr8
mRatBN7.21495,456,330 - 95,497,483 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1495,456,330 - 95,496,830 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1499,803,600 - 99,844,293 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.014101,043,941 - 101,084,634 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01497,517,465 - 97,558,157 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.014106,208,174 - 106,249,322 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl14106,208,176 - 106,248,539 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.014106,274,948 - 106,316,095 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.414102,072,724 - 102,113,561 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.114102,091,934 - 102,132,772 (-)NCBI
Celera1494,469,316 - 94,509,727 (-)NCBICelera
Cytogenetic Map14q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Ugp2RatBardet-Biedl syndrome  ISOUGP2 (Homo sapiens)8554872ClinVar Annotator: match by term: Bardet-Biedl syndromeClinVarPMID:28492532
Ugp2Ratdevelopmental and epileptic encephalopathy 83  ISOUGP2 (Homo sapiens)8554872ClinVar Annotator: match by term: Developmental and epileptic encephalopathy and 83ClinVarPMID:25741868 more ...
Ugp2Ratgenetic disease  ISOUGP2 (Homo sapiens)8554872ClinVar Annotator: match by term: Inborn genetic diseasesClinVarPMID:25741868
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Ugp2Ratdevelopmental and epileptic encephalopathy 83  ISOUGP2 (Homo sapiens)7240710 OMIM 

1 to 20 of 126 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Ugp2Rat(S)-nicotine increases expressionISOUGP2 (Homo sapiens)6480464Nicotine results in increased expression of UGP2 mRNACTDPMID:18247414
Ugp2Rat1,2-dimethylhydrazine multiple interactionsISOUgp2 (Mus musculus)6480464[1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of UGP2 mRNACTDPMID:22206623
Ugp2Rat1,2-dimethylhydrazine decreases expressionISOUgp2 (Mus musculus)64804641 and 2-Dimethylhydrazine results in decreased expression of UGP2 mRNACTDPMID:22206623
Ugp2Rat17alpha-ethynylestradiol increases expressionISOUgp2 (Mus musculus)6480464Ethinyl Estradiol results in increased expression of UGP2 mRNACTDPMID:17942748
Ugp2Rat17alpha-ethynylestradiol multiple interactionsISOUgp2 (Mus musculus)6480464[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of UGP2 mRNACTDPMID:17942748
Ugp2Rat17beta-estradiol decreases expressionEXP 6480464Estradiol results in decreased expression of UGP2 mRNACTDPMID:32145629
Ugp2Rat17beta-estradiol decreases expressionISOUgp2 (Mus musculus)6480464Estradiol results in decreased expression of UGP2 mRNACTDPMID:39298647
Ugp2Rat2,2',4,4'-Tetrabromodiphenyl ether decreases expressionEXP 64804642 more ...CTDPMID:21394737
Ugp2Rat2,3,7,8-tetrachlorodibenzodioxine multiple interactionsISOUgp2 (Mus musculus)6480464[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of UGP2 mRNACTDPMID:17942748
Ugp2Rat2,3,7,8-tetrachlorodibenzodioxine affects expressionEXP 6480464Tetrachlorodibenzodioxin affects the expression of UGP2 mRNACTDPMID:34747641
Ugp2Rat2,3,7,8-tetrachlorodibenzodioxine affects expressionISOUgp2 (Mus musculus)6480464Tetrachlorodibenzodioxin affects the expression of UGP2 mRNACTDPMID:21570461 more ...
Ugp2Rat2,3,7,8-tetrachlorodibenzodioxine decreases expressionEXP 6480464Tetrachlorodibenzodioxin results in decreased expression of UGP2 mRNACTDPMID:21215274
Ugp2Rat2,3,7,8-tetrachlorodibenzodioxine decreases expressionISOUgp2 (Mus musculus)6480464Tetrachlorodibenzodioxin results in decreased expression of UGP2 mRNACTDPMID:19770486
Ugp2Rat2,3,7,8-tetrachlorodibenzodioxine increases expressionISOUgp2 (Mus musculus)6480464Tetrachlorodibenzodioxin results in increased expression of UGP2 mRNACTDPMID:19465110
Ugp2Rat2,6-dimethoxyphenol multiple interactionsISOUGP2 (Homo sapiens)6480464[pyrogallol 1 more ...CTDPMID:38598786
Ugp2Rat2-bromohexadecanoic acid multiple interactionsISOUGP2 (Homo sapiens)64804642-bromopalmitate inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased palmitoylation of UGP2 protein]CTDPMID:38195004
Ugp2Rat2-methylcholine affects expressionISOUGP2 (Homo sapiens)6480464beta-methylcholine affects the expression of UGP2 mRNACTDPMID:21179406
Ugp2Rat2-naphthylamine increases expressionISOUGP2 (Homo sapiens)64804642-Naphthylamine results in increased expression of UGP2 mRNACTDPMID:18247414
Ugp2Rat3-chloropropane-1,2-diol increases expressionEXP 6480464alpha-Chlorohydrin results in increased expression of UGP2 proteinCTDPMID:34915118
Ugp2Rat3-phenylprop-2-enal increases expressionISOUGP2 (Homo sapiens)6480464cinnamaldehyde results in increased expression of UGP2 mRNACTDPMID:17178418

1 to 20 of 126 rows

Biological Process
1 to 19 of 19 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Ugp2Ratbrain development involved_inISOUGP2 (Homo sapiens)1624291 PMID:31820119RGDPMID:31820119
Ugp2Ratbrain development involved_inIEAUniProtKB:Q16851 and ensembl:ENSP000003387031600115GO_REF:0000107EnsemblGO_REF:0000107
Ugp2Ratglucose 1-phosphate metabolic process  IDA 2303740 RGD 
Ugp2Ratglucose 1-phosphate metabolic process  IDA 2303737 RGD 
Ugp2Ratglycogen biosynthetic process involved_inIEAUniPathway:UPA001641600115GO_REF:0000041UniProtGO_REF:0000041
Ugp2Ratglycogen biosynthetic process involved_inIEAUniProtKB:Q91ZJ5 and ensembl:ENSMUSP000000999391600115GO_REF:0000107EnsemblGO_REF:0000107
Ugp2Ratglycogen biosynthetic process involved_inIEAUniProtKB:Q16851 and ensembl:ENSP000003387031600115GO_REF:0000107EnsemblGO_REF:0000107
Ugp2Ratglycogen biosynthetic process involved_inISOUgp2 (Mus musculus)1624291 PMID:32286295RGDPMID:32286295
Ugp2Ratglycogen biosynthetic process involved_inISOUGP2 (Homo sapiens)1624291 PMID:31820119RGDPMID:31820119
Ugp2Ratglycogen metabolic process involved_inIBACGD:CAL0000175518 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Ugp2RatUDP-alpha-D-glucose metabolic process  IDA 2303740 RGD 
Ugp2RatUDP-alpha-D-glucose metabolic process  IDA 2303737 RGD 
Ugp2RatUDP-alpha-D-glucose metabolic process involved_inIEAUniProtKB:Q16851 and ensembl:ENSP000003387031600115GO_REF:0000107EnsemblGO_REF:0000107
Ugp2RatUDP-alpha-D-glucose metabolic process involved_inIEAUniRule:UR0006897511600115GO_REF:0000104UniProtGO_REF:0000104
Ugp2RatUDP-alpha-D-glucose metabolic process involved_inIBACGD:CAL0000175518 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Ugp2RatUDP-alpha-D-glucose metabolic process involved_inIEAInterPro:IPR0162671600115GO_REF:0000002InterProGO_REF:0000002
Ugp2RatUDP-alpha-D-glucose metabolic process involved_inISOUGP2 (Homo sapiens)1624291 PMID:22132858 more ...RGDPMID:22132858 more ...
Ugp2RatUDP-glucuronate biosynthetic process involved_inISOUgp2 (Mus musculus)1624291 PMID:32286295RGDPMID:32286295
Ugp2RatUDP-glucuronate biosynthetic process involved_inIEAUniProtKB:Q91ZJ5 and ensembl:ENSMUSP000000999391600115GO_REF:0000107EnsemblGO_REF:0000107
1 to 19 of 19 rows

Cellular Component

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Ugp2Ratcytoplasm is_active_inIBACGD:CAL0000175518 and PANTHER:PTN0002371301600115GO_REF:0000033GO_CentralGO_REF:0000033

Molecular Function
1 to 20 of 22 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Ugp2RatD-glucose binding  IDA 2303737glucose 1-phosphateRGD 
Ugp2RatD-glucose binding  IDA 2303740glucose 1-phosphateRGD 
Ugp2Ratidentical protein binding enablesISOUGP2 (Homo sapiens)1624291UniProtKB:Q16851 more ...RGDPMID:16189514 more ...
Ugp2Ratidentical protein binding enablesIEAUniProtKB:Q16851 and ensembl:ENSP000003387031600115GO_REF:0000107EnsemblGO_REF:0000107
Ugp2Ratnucleotidyltransferase activity enablesIEAUniProtKB-KW:KW-05481600115GO_REF:0000043UniProtGO_REF:0000043
Ugp2Ratprotein binding enablesISOUGP2 (Homo sapiens)1624291UniProtKB:O14901 more ...RGDPMID:16189514 more ...
Ugp2Ratpyrimidine ribonucleotide binding  IDA 2303740UTPRGD 
Ugp2Ratpyrimidine ribonucleotide binding  IDA 2303737UTPRGD 
Ugp2Rattransferase activity enablesIEAUniProtKB-KW:KW-08081600115GO_REF:0000043UniProtGO_REF:0000043
Ugp2Raturidylyltransferase activity enablesIEAInterPro:IPR0026181600115GO_REF:0000002InterProGO_REF:0000002
Ugp2RatUTP-monosaccharide-1-phosphate uridylyltransferase activity enablesIEAUniProtKB:Q91ZJ5 and ensembl:ENSMUSP000000999391600115GO_REF:0000107EnsemblGO_REF:0000107
Ugp2RatUTP-monosaccharide-1-phosphate uridylyltransferase activity enablesISOUgp2 (Mus musculus)1624291 PMID:32286295RGDPMID:32286295
Ugp2RatUTP:glucose-1-phosphate uridylyltransferase activity  IDA 2303740 RGD 
Ugp2RatUTP:glucose-1-phosphate uridylyltransferase activity enablesIEAUniProtKB:Q91ZJ5 and ensembl:ENSMUSP000000999391600115GO_REF:0000107EnsemblGO_REF:0000107
Ugp2RatUTP:glucose-1-phosphate uridylyltransferase activity enablesIEARHEA:198891600115GO_REF:0000116RHEAGO_REF:0000116
Ugp2RatUTP:glucose-1-phosphate uridylyltransferase activity enablesIEAInterPro:IPR0162671600115GO_REF:0000002InterProGO_REF:0000002
Ugp2RatUTP:glucose-1-phosphate uridylyltransferase activity enablesIEAEC:2.7.7.91600115GO_REF:0000003UniProtGO_REF:0000003
Ugp2RatUTP:glucose-1-phosphate uridylyltransferase activity enablesIEAUniProtKB:Q16851 and ensembl:ENSP000003387031600115GO_REF:0000107EnsemblGO_REF:0000107
Ugp2RatUTP:glucose-1-phosphate uridylyltransferase activity enablesISOUgp2 (Mus musculus)1624291 PMID:32286295RGDPMID:32286295
Ugp2RatUTP:glucose-1-phosphate uridylyltransferase activity enablesIBACGD:CAL0000175518 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
1 to 20 of 22 rows

Imported Annotations - KEGG (archival)

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Ugp2Ratamino sugar metabolic pathway  IEA 6907045 KEGGrno:00520
Ugp2Ratgalactose metabolic pathway  IEA 6907045 KEGGrno:00052
Ugp2Ratnucleotide sugar metabolic pathway  IEA 6907045 KEGGrno:00520
Ugp2Ratpentose and glucuronate interconversion pathway  IEA 6907045 KEGGrno:00040
Ugp2Ratstarch and sucrose metabolic pathway  IEA 6907045 KEGGrno:00500

1 to 9 of 9 rows
#
Reference Title
Reference Citation
1. Control of glucuronidation during hypoxia. Limitation by UDP-glucose pyrophosphorylase. Aw TY and Jones DP, Biochem J. 1984 May 1;219(3):707-12.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
4. The concentration and control of cytoplasmic free inorganic pyrophosphate in rat liver in vivo. Guynn RW, etal., Biochem J. 1974 Jun;140(3):369-75.
5. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
6. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
7. SMPDB Annotation Import Pipeline Pipeline to import SMPDB annotations from SMPDB into RGD
8. GOA pipeline RGD automated data pipeline
9. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
1 to 9 of 9 rows
PMID:5427280   PMID:12477932   PMID:16189514   PMID:19056867   PMID:20458337   PMID:21630459   PMID:21988832   PMID:23376485   PMID:23533145   PMID:25416956  



Ugp2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81499,657,637 - 99,698,573 (-)NCBIGRCr8
mRatBN7.21495,456,330 - 95,497,483 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1495,456,330 - 95,496,830 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1499,803,600 - 99,844,293 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.014101,043,941 - 101,084,634 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01497,517,465 - 97,558,157 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.014106,208,174 - 106,249,322 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl14106,208,176 - 106,248,539 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.014106,274,948 - 106,316,095 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.414102,072,724 - 102,113,561 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.114102,091,934 - 102,132,772 (-)NCBI
Celera1494,469,316 - 94,509,727 (-)NCBICelera
Cytogenetic Map14q22NCBI
UGP2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38263,840,969 - 63,891,560 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl263,840,952 - 63,891,562 (+)EnsemblGRCh38hg38GRCh38
GRCh37264,068,103 - 64,118,694 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36263,921,602 - 63,972,200 (+)NCBINCBI36Build 36hg18NCBI36
Build 34263,980,664 - 64,030,346NCBI
Celera263,913,075 - 63,963,963 (+)NCBICelera
Cytogenetic Map2p15NCBI
HuRef263,807,585 - 63,858,409 (+)NCBIHuRef
CHM1_1263,998,438 - 64,048,971 (+)NCBICHM1_1
T2T-CHM13v2.0263,848,515 - 63,899,116 (+)NCBIT2T-CHM13v2.0
Ugp2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391121,271,126 - 21,321,267 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1121,271,138 - 21,321,201 (-)EnsemblGRCm39 Ensembl
GRCm381121,321,126 - 21,371,267 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1121,321,138 - 21,371,201 (-)EnsemblGRCm38mm10GRCm38
MGSCv371121,221,141 - 21,270,882 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361121,221,147 - 21,270,478 (-)NCBIMGSCv36mm8
Celera1123,469,505 - 23,519,228 (-)NCBICelera
Cytogenetic Map11A3.1NCBI
cM Map1113.89NCBI
Ugp2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542420,444,405 - 20,490,379 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495542420,444,974 - 20,490,016 (-)NCBIChiLan1.0ChiLan1.0
UGP2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21262,507,777 - 62,560,210 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12A62,511,728 - 62,564,161 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02A63,906,778 - 63,959,346 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12A65,032,218 - 65,084,510 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A65,043,871 - 65,084,175 (+)Ensemblpanpan1.1panPan2
UGP2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11063,532,366 - 63,598,362 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1063,533,171 - 63,597,452 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1063,421,118 - 63,487,241 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01064,541,209 - 64,607,376 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1064,541,236 - 64,607,362 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11064,223,314 - 64,289,173 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01064,531,998 - 64,598,118 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01064,824,849 - 64,890,750 (+)NCBIUU_Cfam_GSD_1.0
Ugp2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440629219,736,308 - 19,797,383 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364918,773,892 - 8,837,661 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364918,773,910 - 8,834,984 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
UGP2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl377,975,441 - 78,031,703 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1377,975,450 - 78,032,471 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2381,978,534 - 82,014,755 (-)NCBISscrofa10.2Sscrofa10.2susScr3
UGP2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11443,127,718 - 43,181,348 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1443,128,055 - 43,180,569 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604568,680,450 - 68,734,106 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ugp2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247629,564,498 - 9,619,040 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247629,564,500 - 9,619,899 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

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Variants in Ugp2
194 total Variants

Predicted Target Of
Summary Value
Count of predictions:47
Count of miRNA genes:39
Interacting mature miRNAs:45
Transcripts:ENSRNOT00000067668
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 13 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
1582201Sffal2Serum free fatty acids level QTL 240.0002blood free fatty acid amount (VT:0001553)serum free fatty acids level (CMO:0000547)149255388695876975Rat
9590294Uminl4Urine mineral level QTL 45.660.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)1455624247100624247Rat
631213Bw60Body weight QTL604.51retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)147995092195876975Rat
2300197Scl59Serum cholesterol level QTL 59blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)1455147478100147478Rat
631523Pia13Pristane induced arthritis QTL 133.3joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)144079346098037301Rat
1582259Gluco23Glucose level QTL 233.10.0008blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1470053989104886043Rat
634328Hc5Hypercalciuria QTL 52.3urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)1458184885103184885Rat
1582250Gluco26Glucose level QTL 263.30.0009blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)147341532395876975Rat
2317879Alcrsp27Alcohol response QTL 273.30.63response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)1456631369101631369Rat
1641900Alcrsp11Alcohol response QTL 11alcohol metabolism trait (VT:0015089)blood ethanol level (CMO:0000535)1470053989104886043Rat

1 to 10 of 13 rows
RH133427  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21495,456,412 - 95,456,608 (+)MAPPERmRatBN7.2
Rnor_6.014106,208,257 - 106,208,452NCBIRnor6.0
Rnor_5.014106,275,031 - 106,275,226UniSTSRnor5.0
RGSC_v3.414102,072,805 - 102,073,000UniSTSRGSC3.4
Celera1494,469,397 - 94,469,592UniSTS
RH 3.4 Map14755.3UniSTS
Cytogenetic Map14q22UniSTS
BF402398  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21495,461,952 - 95,462,049 (+)MAPPERmRatBN7.2
Rnor_6.014106,213,797 - 106,213,893NCBIRnor6.0
Rnor_5.014106,280,571 - 106,280,667UniSTSRnor5.0
RGSC_v3.414102,078,346 - 102,078,442UniSTSRGSC3.4
Celera1494,474,937 - 94,475,033UniSTS
RH 3.4 Map14755.6UniSTS
Cytogenetic Map14q22UniSTS
RH141780  
Rat AssemblyChrPosition (strand)SourceJBrowse
RH 3.4 Map14753.7UniSTS
Cytogenetic Map14q22UniSTS




alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31



Ensembl Acc Id: ENSRNOT00000067668   ⟹   ENSRNOP00000063786
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1495,456,335 - 95,496,830 (-)Ensembl
Rnor_6.0 Ensembl14106,208,176 - 106,248,539 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000081245   ⟹   ENSRNOP00000073284
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1495,456,330 - 95,482,001 (-)Ensembl
Rnor_6.0 Ensembl14106,208,514 - 106,234,247 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000105335   ⟹   ENSRNOP00000095723
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1495,462,135 - 95,496,830 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000106549   ⟹   ENSRNOP00000081370
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1495,456,330 - 95,482,402 (-)Ensembl
RefSeq Acc Id: NM_001024743   ⟹   NP_001019914
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81499,657,639 - 99,698,002 (-)NCBI
mRatBN7.21495,456,332 - 95,496,695 (-)NCBI
Rnor_6.014106,208,176 - 106,248,539 (-)NCBI
Rnor_5.014106,274,948 - 106,316,095 (-)NCBI
RGSC_v3.414102,072,724 - 102,113,561 (-)RGD
Celera1494,469,316 - 94,509,727 (-)RGD
Sequence:
RefSeq Acc Id: XM_006251538   ⟹   XP_006251600
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81499,657,637 - 99,698,573 (-)NCBI
mRatBN7.21495,456,330 - 95,497,483 (-)NCBI
Rnor_6.014106,208,174 - 106,249,322 (-)NCBI
Rnor_5.014106,274,948 - 106,316,095 (-)NCBI
Sequence:
RefSeq Acc Id: NP_001019914   ⟸   NM_001024743
- UniProtKB: Q4V8I9 (UniProtKB/TrEMBL),   F1LQ84 (UniProtKB/TrEMBL),   A0A9K3Y8H8 (UniProtKB/TrEMBL),   A0A0G2K542 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006251600   ⟸   XM_006251538
- Peptide Label: isoform X1
- Sequence:
Ensembl Acc Id: ENSRNOP00000063786   ⟸   ENSRNOT00000067668
Ensembl Acc Id: ENSRNOP00000073284   ⟸   ENSRNOT00000081245
Ensembl Acc Id: ENSRNOP00000081370   ⟸   ENSRNOT00000106549

Name Modeler Protein Id AA Range Protein Structure
AF-Q4V8I9-F1-model_v2 AlphaFold Q4V8I9 1-508 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

RGD ID:13699514
Promoter ID:EPDNEW_R10038
Type:multiple initiation site
Name:Ugp2_1
Description:UDP-glucose pyrophosphorylase 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.014106,248,567 - 106,248,627EPDNEW


1 to 38 of 38 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-14829 BioCyc
BioCyc Pathway PWY-7343 [UDP-alpha-D-glucose biosynthesis] BioCyc
BioCyc Pathway Image PWY-7343 BioCyc
Ensembl Genes ENSRNOG00000008079 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000067668 ENTREZGENE
  ENSRNOT00000067668.4 UniProtKB/TrEMBL
  ENSRNOT00000081245 ENTREZGENE
  ENSRNOT00000081245.2 UniProtKB/TrEMBL
  ENSRNOT00000105335.1 UniProtKB/TrEMBL
  ENSRNOT00000106549.1 UniProtKB/TrEMBL
Gene3D-CATH Hexapeptide repeat proteins UniProtKB/TrEMBL
  Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7302845 IMAGE-MGC_LOAD
  IMAGE:7443949 IMAGE-MGC_LOAD
InterPro Nucleotide-diphossugar_trans UniProtKB/TrEMBL
  Trimer_LpxA-like_sf UniProtKB/TrEMBL
  UDPGP_trans UniProtKB/TrEMBL
  UDPGP_trans_subgr UniProtKB/TrEMBL
KEGG Report rno:289827 UniProtKB/TrEMBL
MGC_CLONE MGC:105978 IMAGE-MGC_LOAD
  MGC:114404 IMAGE-MGC_LOAD
NCBI Gene 289827 ENTREZGENE
PANTHER PTHR43511 UniProtKB/TrEMBL
Pfam UDPGP UniProtKB/TrEMBL
PhenoGen Ugp2 PhenoGen
PIRSF UDPGP UniProtKB/TrEMBL
RatGTEx ENSRNOG00000008079 RatGTEx
Superfamily-SCOP SSF53448 UniProtKB/TrEMBL
  Trimeric LpxA-like enzymes UniProtKB/TrEMBL
UniProt A0A0G2K542 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6ANT4_RAT UniProtKB/TrEMBL
  A0A8I6G7V9 ENTREZGENE, UniProtKB/TrEMBL
  A0A9K3Y8H8 ENTREZGENE, UniProtKB/TrEMBL
  A6JQ39_RAT UniProtKB/TrEMBL
  F1LQ84 ENTREZGENE
  Q4V8I9 ENTREZGENE, UniProtKB/TrEMBL
  Q5XFW3_RAT UniProtKB/TrEMBL
UniProt Secondary F1LQ84 UniProtKB/TrEMBL
1 to 38 of 38 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2005-12-06 Ugp2  UDP-glucose pyrophosphorylase 2  Ugp2_predicted  UDP-glucose pyrophosphorylase 2 (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Ugp2_predicted  UDP-glucose pyrophosphorylase 2 (predicted)      Symbol and Name status set to approved 70820 APPROVED