Prg4 (proteoglycan 4) - Rat Genome Database

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Gene: Prg4 (proteoglycan 4) Rattus norvegicus
Analyze
Symbol: Prg4
Name: proteoglycan 4
RGD ID: 1308976
Description: Predicted to enable polysaccharide binding activity and scavenger receptor activity. Predicted to be involved in immune response and vesicle-mediated transport. Predicted to act upstream of or within hematopoietic stem cell proliferation; negative regulation of interleukin-6 production; and regulation of cell population proliferation. Predicted to be active in collagen-containing extracellular matrix and extracellular space. Human ortholog(s) of this gene implicated in camptodactyly-arthropathy-coxa vara-pericarditis syndrome and pericarditis. Orthologous to human PRG4 (proteoglycan 4); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; acetamide; acrylamide.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC289104; lubricin; proteoglycan 4, (megakaryocyte stimulating factor, articular superficial zone protein, camptodactyly, arthropathy, coxa vara, pericarditis syndrome)
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81365,037,363 - 65,054,764 (-)NCBIGRCr8
mRatBN7.21362,487,257 - 62,504,657 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1362,487,257 - 62,504,119 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1365,133,642 - 65,150,474 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01366,404,875 - 66,421,792 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01363,666,116 - 63,683,057 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01367,672,588 - 67,688,902 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1367,672,878 - 67,688,477 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01372,637,409 - 72,653,723 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41364,753,316 - 64,769,533 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11364,767,685 - 64,783,195 (-)NCBI
Celera1362,446,883 - 62,463,361 (-)NCBICelera
Cytogenetic Map13q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model



  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Prg4Ratpericarditis  ISOPRG4 (Homo sapiens)1580712 RGD 
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Prg4Ratarthrogryposis multiplex congenita  ISOPRG4 (Homo sapiens)8554872ClinVar Annotator: match by term: Guérin-Stern syndromeClinVarPMID:25741868 and PMID:31680123
Prg4Ratcamptodactyly-arthropathy-coxa vara-pericarditis syndrome  ISOPRG4 (Homo sapiens)8554872ClinVar more ...ClinVarPMID:10545950 more ...
Prg4Ratfetal akinesia deformation sequence syndrome  ISOPRG4 (Homo sapiens)8554872ClinVar Annotator: match by term: Pena Shokeir syndrome and type 1ClinVarPMID:25741868 and PMID:31680123
Prg4Ratfetal akinesia deformation sequence syndrome 1  ISOPRG4 (Homo sapiens)8554872ClinVar Annotator: match by term: Fetal akinesia sequenceClinVarPMID:25741868 and PMID:31680123
Prg4Ratgastrointestinal stromal tumor  ISOPRG4 (Homo sapiens)8554872ClinVar Annotator: match by term: Gastrointestinal stromal tumorClinVarPMID:28492532
Prg4Ratgenetic disease  ISOPRG4 (Homo sapiens)8554872ClinVar Annotator: match by term: Inborn genetic diseasesClinVar 
Prg4Ratparathyroid carcinoma  ISOPRG4 (Homo sapiens)8554872ClinVar Annotator: match by term: Parathyroid carcinomaClinVarPMID:28492532
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Prg4Ratcamptodactyly-arthropathy-coxa vara-pericarditis syndrome  ISOPRG4 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:10545950
Prg4RatContracture  ISOPRG4 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:10545950
Prg4RatHyperplasia  ISOPRG4 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:10545950
Prg4Ratpericarditis  ISOPRG4 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:10545950
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Prg4Ratcamptodactyly-arthropathy-coxa vara-pericarditis syndrome  ISOPRG4 (Homo sapiens)7240710 OMIM 

1 to 20 of 94 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Prg4Rat(1->4)-beta-D-glucan multiple interactionsISOPrg4 (Mus musculus)6480464[perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of PRG4 mRNACTDPMID:36331819
Prg4Rat(S)-nicotine decreases expressionISOPrg4 (Mus musculus)6480464Nicotine results in decreased expression of PRG4 mRNACTDPMID:33640489
Prg4Rat1,2-dichloroethane increases expressionISOPrg4 (Mus musculus)6480464ethylene dichloride results in increased expression of PRG4 mRNACTDPMID:28960355
Prg4Rat17alpha-ethynylestradiol multiple interactionsISOPrg4 (Mus musculus)6480464[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of PRG4 mRNACTDPMID:17942748
Prg4Rat17beta-estradiol increases expressionISOPrg4 (Mus musculus)6480464Estradiol results in increased expression of PRG4 mRNACTDPMID:19484750 and PMID:39298647
Prg4Rat2,3,7,8-tetrachlorodibenzodioxine multiple interactionsISOPrg4 (Mus musculus)6480464[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of PRG4 mRNACTDPMID:17942748
Prg4Rat2,3,7,8-tetrachlorodibenzodioxine increases expressionEXP 6480464Tetrachlorodibenzodioxin results in increased expression of PRG4 mRNACTDPMID:32109520 and PMID:34747641
Prg4Rat2,3,7,8-tetrachlorodibenzodioxine decreases expressionISOPRG4 (Homo sapiens)6480464Tetrachlorodibenzodioxin results in decreased expression of PRG4 mRNACTDPMID:21296121
Prg4Rat2,4-dibromophenyl 2,4,5-tribromophenyl ether affects expressionISOPrg4 (Mus musculus)64804642 more ...CTDPMID:38648751
Prg4Rat4,4'-sulfonyldiphenol affects expressionISOPrg4 (Mus musculus)6480464bisphenol S affects the expression of PRG4 mRNACTDPMID:39298647
Prg4Ratacetamide decreases expressionEXP 6480464acetamide results in decreased expression of PRG4 mRNACTDPMID:31881176
Prg4Ratacrylamide decreases expressionEXP 6480464Acrylamide results in decreased expression of PRG4 mRNACTDPMID:28959563
Prg4Rataflatoxin B1 decreases expressionISOPRG4 (Homo sapiens)6480464Aflatoxin B1 results in decreased expression of PRG4 mRNACTDPMID:27153756
Prg4Rataflatoxin B1 increases methylationISOPRG4 (Homo sapiens)6480464Aflatoxin B1 results in increased methylation of PRG4 polyA tailCTDPMID:30157460
Prg4Rataflatoxin B1 decreases methylationISOPRG4 (Homo sapiens)6480464Aflatoxin B1 results in decreased methylation of PRG4 geneCTDPMID:27153756
Prg4Ratalpha-Zearalanol multiple interactionsEXP 6480464[Zeranol co-treated with perfluorooctanoic acid] results in decreased expression of PRG4 mRNACTDPMID:35163327
Prg4Ratamphetamine increases expressionEXP 6480464Amphetamine results in increased expression of PRG4 mRNACTDPMID:30779732
Prg4Rataristolochic acid A increases expressionISOPRG4 (Homo sapiens)6480464aristolochic acid I results in increased expression of PRG4 mRNACTDPMID:33212167
Prg4Ratarsenous acid increases expressionISOPRG4 (Homo sapiens)6480464Arsenic Trioxide results in increased expression of PRG4 mRNACTDPMID:20458559
Prg4Ratarsenous acid decreases expressionISOPrg4 (Mus musculus)6480464Arsenic Trioxide results in decreased expression of PRG4 mRNACTDPMID:35676786

1 to 20 of 94 rows

Biological Process

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Prg4Rathematopoietic stem cell proliferation acts_upstream_of_or_withinISOPrg4 (Mus musculus)1624291MGI:3513195 PMID:21939632RGDPMID:21939632
Prg4Ratimmune response involved_inIEAInterPro:IPR0204361600115GO_REF:0000002InterProGO_REF:0000002
Prg4Ratnegative regulation of interleukin-6 production acts_upstream_of_or_withinISOPrg4 (Mus musculus)1624291MGI:3513195 PMID:21939632RGDPMID:21939632
Prg4Ratregulation of cell population proliferation acts_upstream_of_or_withinISOPrg4 (Mus musculus)1624291MGI:3513195 PMID:15719068RGDPMID:15719068
Prg4Ratvesicle-mediated transport involved_inIEAGO:00050441600115GO_REF:0000108GOCGO_REF:0000108

Cellular Component

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Prg4Ratcollagen-containing extracellular matrix is_active_inIBAPANTHER:PTN000531402 and Vtn (Rattus norvegicus)1600115GO_REF:0000033GO_CentralGO_REF:0000033
Prg4Ratextracellular region located_inIEAUniProtKB-KW:KW-09641600115GO_REF:0000043UniProtGO_REF:0000043
Prg4Ratextracellular region located_inIEAUniProtKB-SubCell:SL-02431600115GO_REF:0000044UniProtGO_REF:0000044
Prg4Ratextracellular space located_inISOPrg4 (Mus musculus)1624291 PMID:15719068RGDPMID:15719068
Prg4Ratextracellular space is_active_inIBAMGI:1891344 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033

Molecular Function

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Prg4Ratpolysaccharide binding enablesIEAInterPro:IPR0204361600115GO_REF:0000002InterProGO_REF:0000002
Prg4Ratscavenger receptor activity enablesIEAInterPro:IPR0204361600115GO_REF:0000002InterProGO_REF:0000002


#
Reference Title
Reference Citation
1. Novel PRG4 mutations underlie CACP in Saudi families. Alazami AM, etal., Hum Mutat. 2006 Feb;27(2):213.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
4. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
5. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
PMID:12477932   PMID:15719068   PMID:19790069   PMID:21041994   PMID:21939632   PMID:22009294   PMID:22209395   PMID:22490392   PMID:23176120   PMID:23263781   PMID:24006456   PMID:25039883  
PMID:26631347   PMID:26867127   PMID:26978347   PMID:27559042   PMID:32716572   PMID:34459483   PMID:35917632   PMID:38897120  



Prg4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81365,037,363 - 65,054,764 (-)NCBIGRCr8
mRatBN7.21362,487,257 - 62,504,657 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1362,487,257 - 62,504,119 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1365,133,642 - 65,150,474 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01366,404,875 - 66,421,792 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01363,666,116 - 63,683,057 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01367,672,588 - 67,688,902 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1367,672,878 - 67,688,477 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01372,637,409 - 72,653,723 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41364,753,316 - 64,769,533 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11364,767,685 - 64,783,195 (-)NCBI
Celera1362,446,883 - 62,463,361 (-)NCBICelera
Cytogenetic Map13q21NCBI
PRG4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381186,296,273 - 186,314,567 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1186,296,279 - 186,314,567 (+)EnsemblGRCh38hg38GRCh38
GRCh371186,265,405 - 186,283,699 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361184,532,041 - 184,550,311 (+)NCBINCBI36Build 36hg18NCBI36
Build 341182,997,646 - 183,015,343NCBI
Celera1159,376,110 - 159,394,394 (+)NCBICelera
Cytogenetic Map1q31.1NCBI
HuRef1157,499,953 - 157,518,259 (+)NCBIHuRef
CHM1_11187,687,110 - 187,705,394 (+)NCBICHM1_1
T2T-CHM13v2.01185,650,929 - 185,669,225 (+)NCBIT2T-CHM13v2.0
Prg4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391150,325,163 - 150,341,916 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1150,325,163 - 150,341,916 (-)EnsemblGRCm39 Ensembl
GRCm381150,449,412 - 150,466,221 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1150,449,412 - 150,466,165 (-)EnsemblGRCm38mm10GRCm38
MGSCv371152,296,542 - 152,313,295 (-)NCBIGRCm37MGSCv37mm9NCBIm37
Celera1152,888,564 - 152,905,057 (-)NCBICelera
Cytogenetic Map1G1NCBI
cM Map163.84NCBI
Prg4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495540624,726,483 - 24,742,590 (+)NCBIChiLan1.0ChiLan1.0
PRG4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2163,405,212 - 63,422,384 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1163,086,639 - 63,103,818 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01161,824,271 - 161,842,031 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11165,977,437 - 165,994,170 (+)NCBIpanpan1.1PanPan1.1panPan2
PRG4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1719,360,034 - 19,377,005 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl719,364,609 - 19,376,999 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha718,881,820 - 18,899,655 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0719,096,129 - 19,113,978 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl719,096,096 - 19,113,006 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1719,003,150 - 19,020,789 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0719,112,466 - 19,130,118 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0719,242,817 - 19,260,664 (+)NCBIUU_Cfam_GSD_1.0
Prg4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934486,264,886 - 86,282,252 (-)NCBIHiC_Itri_2
SpeTri2.0NW_0049364814,111,417 - 4,128,411 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PRG4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.19127,463,875 - 127,481,770 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.29139,907,666 - 139,933,143 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PRG4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12543,120,523 - 43,138,886 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2543,120,618 - 43,137,441 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605544,310,416 - 44,327,902 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Prg4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248147,306,190 - 7,320,888 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

.

.
Variants in Prg4
75 total Variants

Predicted Target Of
Summary Value
Count of predictions:130
Count of miRNA genes:98
Interacting mature miRNAs:105
Transcripts:ENSRNOT00000068148
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 30 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
1298066Bp159Blood pressure QTL 1590.004arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)134608804691088046Rat
10755495Bp387Blood pressure QTL 3873.78arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)133466346187525369Rat
1354655Bp241Blood pressure QTL 2413.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1356056920101056920Rat
70220Bp55Blood pressure QTL 555.75arterial blood pressure trait (VT:2000000)blood pressure measurement (CMO:0000003)133737450982374509Rat
71119Thym2Thymus enlargement QTL 23.8thymus mass (VT:0004954)thymus weight to body weight ratio (CMO:0000612)134619797684753113Rat
61391Bp5Blood pressure QTL 55.6arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)132230187567301875Rat
4889861Pur29Proteinuria QTL 2913.80.005urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)133741558480753406Rat
12879441Bp396Blood pressure QTL 396arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)134569998390699983Rat
619615Bp80Blood pressure QTL 800.0354arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)133975454484754544Rat
2303028Bp329Blood pressure QTL 329arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)135849787273485113Rat

1 to 10 of 30 rows
RH138961  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr81365,037,698 - 65,038,519 (+)Marker Load Pipeline
mRatBN7.21362,487,592 - 62,488,413 (+)MAPPERmRatBN7.2
Rnor_6.01367,672,924 - 67,673,744NCBIRnor6.0
Rnor_5.01372,637,745 - 72,638,565UniSTSRnor5.0
RGSC_v3.41364,753,652 - 64,754,472UniSTSRGSC3.4
Celera1362,447,219 - 62,448,039UniSTS
RH 3.4 Map13288.9UniSTS
Cytogenetic Map13q21UniSTS
RH136904  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21362,488,975 - 62,489,188 (+)MAPPERmRatBN7.2
Rnor_6.01367,674,307 - 67,674,519NCBIRnor6.0
Rnor_5.01372,639,128 - 72,639,340UniSTSRnor5.0
RGSC_v3.41364,755,035 - 64,755,247UniSTSRGSC3.4
Celera1362,448,602 - 62,448,814UniSTS
Cytogenetic Map13q21UniSTS




alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 89 91 90 59 25 59 6 218 97 69 45 56 31



Ensembl Acc Id: ENSRNOT00000068148   ⟹   ENSRNOP00000059900
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1362,487,257 - 62,504,119 (-)Ensembl
Rnor_6.0 Ensembl1367,672,878 - 67,688,477 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000113690   ⟹   ENSRNOP00000086666
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1362,487,257 - 62,504,119 (-)Ensembl
RefSeq Acc Id: NM_001105962   ⟹   NP_001099432
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81365,037,363 - 65,054,225 (-)NCBI
mRatBN7.21362,487,257 - 62,504,119 (-)NCBI
Rnor_6.01367,672,588 - 67,688,902 (-)NCBI
Rnor_5.01372,637,409 - 72,653,723 (-)NCBI
RGSC_v3.41364,753,316 - 64,769,533 (-)RGD
Celera1362,446,883 - 62,463,361 (-)RGD
Sequence:
RefSeq Acc Id: XM_039090463   ⟹   XP_038946391
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81365,037,538 - 65,054,764 (-)NCBI
mRatBN7.21362,487,386 - 62,504,657 (-)NCBI
RefSeq Acc Id: XM_039090464   ⟹   XP_038946392
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81365,037,538 - 65,054,762 (-)NCBI
mRatBN7.21362,487,386 - 62,504,654 (-)NCBI
RefSeq Acc Id: XM_039090465   ⟹   XP_038946393
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81365,037,538 - 65,054,763 (-)NCBI
mRatBN7.21362,487,386 - 62,504,656 (-)NCBI
RefSeq Acc Id: XM_039090466   ⟹   XP_038946394
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81365,037,538 - 65,054,758 (-)NCBI
mRatBN7.21362,487,386 - 62,504,650 (-)NCBI
RefSeq Acc Id: XM_039090467   ⟹   XP_038946395
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81365,037,538 - 65,054,756 (-)NCBI
mRatBN7.21362,487,386 - 62,504,648 (-)NCBI
RefSeq Acc Id: NP_001099432   ⟸   NM_001105962
- Peptide Label: precursor
- UniProtKB: F1LRA5 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000059900   ⟸   ENSRNOT00000068148
RefSeq Acc Id: XP_038946391   ⟸   XM_039090463
- Peptide Label: isoform X1
- UniProtKB: F1LRA5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038946393   ⟸   XM_039090465
- Peptide Label: isoform X3
- UniProtKB: F1LRA5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038946392   ⟸   XM_039090464
- Peptide Label: isoform X2
- UniProtKB: F1LRA5 (UniProtKB/TrEMBL)
SMB

Name Modeler Protein Id AA Range Protein Structure
AF-F1LRA5-F1-model_v2 AlphaFold F1LRA5 1-1060 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

RGD ID:13698880
Promoter ID:EPDNEW_R9405
Type:single initiation site
Name:Prg4_1
Description:proteoglycan 4
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01367,688,516 - 67,688,576EPDNEW


1 to 39 of 39 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-17943 BioCyc
Ensembl Genes ENSRNOG00000002385 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000068148 ENTREZGENE
  ENSRNOT00000068148.4 UniProtKB/TrEMBL
  ENSRNOT00000113690 ENTREZGENE
  ENSRNOT00000113690.1 UniProtKB/TrEMBL
  ENSRNOT00000126171 ENTREZGENE
  ENSRNOT00000154575 ENTREZGENE
Gene3D-CATH 2.110.10.10 UniProtKB/TrEMBL
  4.10.410.20 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:9099364 IMAGE-MGC_LOAD
InterPro Heme_transport/Cell_adhesion UniProtKB/TrEMBL
  Hemopexin-like_dom_sf UniProtKB/TrEMBL
  Hemopexin/matrixin UniProtKB/TrEMBL
  Hemopexin/matrixin_CS UniProtKB/TrEMBL
  Hemopexin/matrixin_repeat UniProtKB/TrEMBL
  Somatomedin_B-like_dom UniProtKB/TrEMBL
  Somatomedin_B_chordata UniProtKB/TrEMBL
  Somatomedin_B_dom UniProtKB/TrEMBL
MGC_CLONE MGC:187909 IMAGE-MGC_LOAD
NCBI Gene 289104 ENTREZGENE
PANTHER HEMOPEXIN DOMAIN-CONTAINING PROTEIN UniProtKB/TrEMBL
  PROTEOGLYCAN 4 UniProtKB/TrEMBL
Pfam Hemopexin UniProtKB/TrEMBL
  Somatomedin_B UniProtKB/TrEMBL
PhenoGen Prg4 PhenoGen
PRINTS SOMATOMEDINB UniProtKB/TrEMBL
PROSITE HEMOPEXIN UniProtKB/TrEMBL
  HEMOPEXIN_2 UniProtKB/TrEMBL
  SMB_1 UniProtKB/TrEMBL
  SMB_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000002385 RatGTEx
SMART SM00120 UniProtKB/TrEMBL
  SM00201 UniProtKB/TrEMBL
Superfamily-SCOP Hemopexin UniProtKB/TrEMBL
  SSF90188 UniProtKB/TrEMBL
UniProt A0A8I6A1N7 ENTREZGENE, UniProtKB/TrEMBL
  B0BNA0_RAT UniProtKB/TrEMBL
  F1LRA5 ENTREZGENE, UniProtKB/TrEMBL
1 to 39 of 39 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-03-26 Prg4  proteoglycan 4  Prg4  proteoglycan 4, (megakaryocyte stimulating factor, articular superficial zone protein, camptodactyly, arthropathy, coxa vara, pericarditis syndrome)  Name changed 629549 APPROVED
2008-04-30 Prg4  proteoglycan 4, (megakaryocyte stimulating factor, articular superficial zone protein, camptodactyly, arthropathy, coxa vara, pericarditis syndrome)   Prg4_predicted  proteoglycan 4, (megakaryocyte stimulating factor, articular superficial zone protein, camptodactyly, arthropathy, coxa vara, pericarditis syndrome) (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Prg4_predicted  proteoglycan 4, (megakaryocyte stimulating factor, articular superficial zone protein, camptodactyly, arthropathy, coxa vara, pericarditis syndrome) (predicted)      Symbol and Name status set to approved 70820 APPROVED