Prg4 (proteoglycan 4) - Rat Genome Database

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Gene: Prg4 (proteoglycan 4) Chinchilla lanigera
Analyze
Symbol: Prg4
Name: proteoglycan 4
RGD ID: 9040354
Description: INVOLVED IN hematopoietic stem cell proliferation (ortholog); negative regulation of interleukin-6 production (ortholog); regulation of cell population proliferation (ortholog); ASSOCIATED WITH arthrogryposis multiplex congenita (ortholog); camptodactyly-arthropathy-coxa vara-pericarditis syndrome (ortholog); Contracture (ortholog); FOUND IN extracellular space (ortholog)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495540624,726,483 - 24,742,590 (+)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
2. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Prg4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495540624,726,483 - 24,742,590 (+)NCBIChiLan1.0ChiLan1.0
PRG4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381186,296,273 - 186,314,567 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1186,296,279 - 186,314,567 (+)EnsemblGRCh38hg38GRCh38
GRCh371186,265,405 - 186,283,699 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361184,532,041 - 184,550,311 (+)NCBINCBI36Build 36hg18NCBI36
Build 341182,997,646 - 183,015,343NCBI
Celera1159,376,110 - 159,394,394 (+)NCBICelera
Cytogenetic Map1q31.1NCBI
HuRef1157,499,953 - 157,518,259 (+)NCBIHuRef
CHM1_11187,687,110 - 187,705,394 (+)NCBICHM1_1
T2T-CHM13v2.01185,650,929 - 185,669,225 (+)NCBIT2T-CHM13v2.0
Prg4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391150,325,163 - 150,341,916 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1150,325,163 - 150,341,916 (-)EnsemblGRCm39 Ensembl
GRCm381150,449,412 - 150,466,221 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1150,449,412 - 150,466,165 (-)EnsemblGRCm38mm10GRCm38
MGSCv371152,296,542 - 152,313,295 (-)NCBIGRCm37MGSCv37mm9NCBIm37
Celera1152,888,564 - 152,905,057 (-)NCBICelera
Cytogenetic Map1G1NCBI
cM Map163.84NCBI
Prg4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81365,037,363 - 65,054,764 (-)NCBIGRCr8
mRatBN7.21362,487,257 - 62,504,657 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1362,487,257 - 62,504,119 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1365,133,642 - 65,150,474 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01366,404,875 - 66,421,792 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01363,666,116 - 63,683,057 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01367,672,588 - 67,688,902 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1367,672,878 - 67,688,477 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01372,637,409 - 72,653,723 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41364,753,316 - 64,769,533 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11364,767,685 - 64,783,195 (-)NCBI
Celera1362,446,883 - 62,463,361 (-)NCBICelera
Cytogenetic Map13q21NCBI
PRG4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2163,405,212 - 63,422,384 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1163,086,639 - 63,103,818 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01161,824,271 - 161,842,031 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11165,977,437 - 165,994,170 (+)NCBIpanpan1.1PanPan1.1panPan2
PRG4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1719,360,034 - 19,377,005 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl719,364,609 - 19,376,999 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha718,881,820 - 18,899,655 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0719,096,129 - 19,113,978 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl719,096,096 - 19,113,006 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1719,003,150 - 19,020,789 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0719,112,466 - 19,130,118 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0719,242,817 - 19,260,664 (+)NCBIUU_Cfam_GSD_1.0
Prg4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934486,264,886 - 86,282,252 (-)NCBIHiC_Itri_2
SpeTri2.0NW_0049364814,111,417 - 4,128,411 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PRG4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.19127,463,875 - 127,481,770 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.29139,907,666 - 139,933,143 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PRG4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12543,120,523 - 43,138,886 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2543,120,618 - 43,137,441 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605544,310,416 - 44,327,902 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Prg4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248147,306,190 - 7,320,888 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


RefSeq Acc Id: XM_005375084   ⟹   XP_005375141
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495540624,726,483 - 24,742,590 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005375085   ⟹   XP_005375142
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495540624,726,483 - 24,742,590 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005375086   ⟹   XP_005375143
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495540624,726,483 - 24,742,590 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005375087   ⟹   XP_005375144
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495540624,726,483 - 24,742,590 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013521767   ⟹   XP_013377221
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495540624,726,483 - 24,742,590 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005375141 (Get FASTA)   NCBI Sequence Viewer  
  XP_005375142 (Get FASTA)   NCBI Sequence Viewer  
  XP_005375143 (Get FASTA)   NCBI Sequence Viewer  
  XP_005375144 (Get FASTA)   NCBI Sequence Viewer  
  XP_013377221 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000013322.1
RefSeq Acc Id: XP_005375141   ⟸   XM_005375084
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_005375142   ⟸   XM_005375085
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_005375144   ⟸   XM_005375087
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_005375143   ⟸   XM_005375086
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_013377221   ⟸   XM_013521767
- Peptide Label: isoform X5
- Sequence:
Protein Domains
SMB


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000009204 UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000013474.1 UniProtKB/TrEMBL
Gene3D-CATH 2.110.10.10 UniProtKB/TrEMBL
  4.10.410.20 UniProtKB/TrEMBL
InterPro Heme_transport/Cell_adhesion UniProtKB/TrEMBL
  Hemopexin-like_dom UniProtKB/TrEMBL
  Hemopexin-like_dom_sf UniProtKB/TrEMBL
  Hemopexin-like_repeat UniProtKB/TrEMBL
  Hemopexin_CS UniProtKB/TrEMBL
  SMB_chordata UniProtKB/TrEMBL
  Somatomedin_B-like_dom_sf UniProtKB/TrEMBL
  Somatomedin_B_dom UniProtKB/TrEMBL
NCBI Gene Prg4 ENTREZGENE
PANTHER HEMOPEXIN DOMAIN-CONTAINING PROTEIN UniProtKB/TrEMBL
  PROTEOGLYCAN 4 UniProtKB/TrEMBL
Pfam Hemopexin UniProtKB/TrEMBL
  Somatomedin_B UniProtKB/TrEMBL
PRINTS SOMATOMEDINB UniProtKB/TrEMBL
PROSITE HEMOPEXIN UniProtKB/TrEMBL
  HEMOPEXIN_2 UniProtKB/TrEMBL
  SMB_1 UniProtKB/TrEMBL
  SMB_2 UniProtKB/TrEMBL
SMART SM00120 UniProtKB/TrEMBL
  SM00201 UniProtKB/TrEMBL
Superfamily-SCOP SSF50923 UniProtKB/TrEMBL
  SSF90188 UniProtKB/TrEMBL
UniProt A0A8C2YPA7_CHILA UniProtKB/TrEMBL