Symbol:
Hibch
Name:
3-hydroxyisobutyryl-CoA hydrolase
RGD ID:
1308392
Description:
Predicted to enable 3-hydroxyisobutyryl-CoA hydrolase activity. Predicted to be involved in valine catabolic process. Predicted to be located in membrane. Predicted to be active in mitochondrion. Human ortholog(s) of this gene implicated in 3-hydroxyisobutryl-CoA hydrolase deficiency. Orthologous to human HIBCH (3-hydroxyisobutyryl-CoA hydrolase); PARTICIPATES IN 3-hydroxy-3-methylglutaryl-CoA lyase deficiency pathway; 3-hydroxyisobutyric aciduria pathway; 3-methylcrotonyl CoA carboxylase 1 deficiency pathway; INTERACTS WITH 3-chloropropane-1,2-diol; bisphenol A; Brodifacoum.
Type:
protein-coding
RefSeq Status:
VALIDATED
Previously known as:
3-hydroxyisobutyryl-CoA hydrolase, mitochondrial; 3-hydroxyisobutyryl-Coenzyme A hydrolase; HIB-CoA hydrolase; HIBYL-CoA-H; LOC301384
RGD Orthologs
Alliance Orthologs
More Info
more info ...
More Info
Latest Assembly:
GRCr8 - GRCr8 Assembly
Position:
Rat Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCr8 9 56,082,082 - 56,161,796 (-) NCBI GRCr8 mRatBN7.2 9 48,590,097 - 48,669,896 (-) NCBI mRatBN7.2 mRatBN7.2 mRatBN7.2 Ensembl 9 48,590,099 - 48,669,824 (-) Ensembl mRatBN7.2 Ensembl UTH_Rnor_SHR_Utx 9 57,131,763 - 57,211,849 (-) NCBI Rnor_SHR UTH_Rnor_SHR_Utx UTH_Rnor_SHRSP_BbbUtx_1.0 9 62,254,592 - 62,334,677 (-) NCBI Rnor_SHRSP UTH_Rnor_SHRSP_BbbUtx_1.0 UTH_Rnor_WKY_Bbb_1.0 9 60,550,578 - 60,630,667 (-) NCBI Rnor_WKY UTH_Rnor_WKY_Bbb_1.0 Rnor_6.0 9 53,446,185 - 53,526,727 (-) NCBI Rnor6.0 Rnor_6.0 rn6 Rnor6.0 Rnor_6.0 Ensembl 9 53,446,194 - 53,526,728 (-) Ensembl Rnor6.0 rn6 Rnor6.0 Rnor_5.0 9 53,112,579 - 53,193,190 (-) NCBI Rnor5.0 Rnor_5.0 rn5 Rnor5.0 RGSC_v3.4 9 45,564,702 - 45,645,252 (-) NCBI RGSC3.4 RGSC_v3.4 rn4 RGSC3.4 RGSC_v3.1 9 45,566,124 - 45,624,624 (-) NCBI Celera 9 46,259,906 - 46,339,124 (-) NCBI Celera Cytogenetic Map 9 q22 NCBI
JBrowse:
View Region in Genome Browser (JBrowse)
Model
Hibch Rat 3-hydroxyisobutryl-CoA hydrolase deficiency ISO RGD:1318134 8554872 ClinVar Annotator: match by term: 3-hydroxyisobutyryl-CoA hydrolase deficiency | ClinVar Annotator: match by term: Neurodegeneration more ... ClinVar PMID:16199547|PMID:17160907|PMID:17576681|PMID:24033266|PMID:24299452|PMID:25251209|PMID:25591832|PMID:25741868|PMID:26026795|PMID:26163321|PMID:26717663|PMID:27400804|PMID:27435318|PMID:27896122|PMID:28454995|PMID:28492532|PMID:29703962|PMID:30111474|PMID:30847210|PMID:32022391|PMID:32334381|PMID:32677093|PMID:33762937|PMID:36200804|PMID:7122152|PMID:9536098 Hibch Rat genetic disease ISO RGD:1318134 8554872 ClinVar Annotator: match by term: Inborn genetic diseases ClinVar PMID:17160907|PMID:25741868|PMID:27896122|PMID:28492532|PMID:32677093 Hibch Rat immunodeficiency 31B ISO RGD:1318134 8554872 ClinVar Annotator: match by term: Immunodeficiency 31B ClinVar PMID:28492532 Hibch Rat mitochondrial metabolism disease ISO RGD:1318134 8554872 ClinVar Annotator: match by term: Mitochondrial disease ClinVar Hibch Rat Neurodevelopmental Disorders ISO RGD:1318134 8554872 ClinVar Annotator: match by term: Neurodevelopmental disorder ClinVar PMID:25741868
Only show annotations with direct experimental evidence (0 objects hidden)
Hibch Rat (-)-epigallocatechin 3-gallate multiple interactions ISO RGD:1318134 6480464 [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of HIBCH mRNA CTD PMID:22079256 Hibch Rat (1->4)-beta-D-glucan multiple interactions ISO RGD:1318135 6480464 [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of HIBCH mRNA CTD PMID:36331819 Hibch Rat 1,1-dichloroethene decreases expression ISO RGD:1318135 6480464 vinylidene chloride results in decreased expression of HIBCH mRNA CTD PMID:26682919 Hibch Rat 1,2-dimethylhydrazine multiple interactions ISO RGD:1318135 6480464 [1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of HIBCH mRNA CTD PMID:22206623 Hibch Rat 1,2-dimethylhydrazine decreases expression ISO RGD:1318135 6480464 1,2-Dimethylhydrazine results in decreased expression of HIBCH mRNA CTD PMID:22206623 Hibch Rat 17beta-estradiol multiple interactions ISO RGD:1318134 6480464 [Estradiol co-treated with Progesterone] results in increased expression of HIBCH mRNA CTD PMID:20660070 Hibch Rat 2-methylcholine affects expression ISO RGD:1318134 6480464 beta-methylcholine affects the expression of HIBCH mRNA CTD PMID:21179406 Hibch Rat 3-chloropropane-1,2-diol increases expression EXP 6480464 alpha-Chlorohydrin results in increased expression of HIBCH protein CTD PMID:34915118 Hibch Rat 4,4'-sulfonyldiphenol increases expression ISO RGD:1318135 6480464 bisphenol S results in increased expression of HIBCH mRNA CTD PMID:39298647 Hibch Rat 4,4'-sulfonyldiphenol increases expression ISO RGD:1318134 6480464 bisphenol S results in increased expression of HIBCH protein CTD PMID:34186270 Hibch Rat 4-hydroxyphenyl retinamide decreases expression ISO RGD:1318135 6480464 Fenretinide results in decreased expression of HIBCH mRNA CTD PMID:28973697 Hibch Rat acryloyl-CoA increases abundance ISO RGD:1318134 6480464 HIBCH gene mutant form results in increased abundance of acryloyl-coenzyme A CTD PMID:25125611 Hibch Rat aflatoxin B1 decreases expression ISO RGD:1318134 6480464 Aflatoxin B1 results in decreased expression of HIBCH mRNA CTD PMID:27153756 Hibch Rat aflatoxin B1 decreases methylation ISO RGD:1318134 6480464 Aflatoxin B1 results in decreased methylation of HIBCH gene CTD PMID:27153756 Hibch Rat aldehydo-D-glucose decreases secretion ISO RGD:1318134 6480464 Glucose deficiency results in decreased secretion of HIBCH protein CTD PMID:24802182 Hibch Rat all-trans-retinoic acid decreases expression ISO RGD:1318134 6480464 Tretinoin results in decreased expression of HIBCH mRNA CTD PMID:33167477 Hibch Rat antirheumatic drug increases expression ISO RGD:1318134 6480464 Antirheumatic Agents results in increased expression of HIBCH mRNA CTD PMID:24449571 Hibch Rat aristolochic acid A decreases expression ISO RGD:1318134 6480464 aristolochic acid I results in decreased expression of HIBCH mRNA CTD PMID:33212167 Hibch Rat aristolochic acid A increases expression ISO RGD:1318134 6480464 aristolochic acid I results in increased expression of HIBCH protein CTD PMID:33212167 Hibch Rat benzo[a]pyrene decreases methylation ISO RGD:1318134 6480464 Benzo(a)pyrene results in decreased methylation of HIBCH promoter CTD PMID:27901495 Hibch Rat benzo[a]pyrene decreases expression ISO RGD:1318134 6480464 Benzo(a)pyrene results in decreased expression of HIBCH protein CTD PMID:33278487 Hibch Rat beta-lapachone decreases expression ISO RGD:1318134 6480464 beta-lapachone results in decreased expression of HIBCH mRNA CTD PMID:38218311 Hibch Rat bis(2-ethylhexyl) phthalate increases expression ISO RGD:1318135 6480464 Diethylhexyl Phthalate results in increased expression of HIBCH mRNA CTD PMID:19850644|PMID:34319233 Hibch Rat bis(2-ethylhexyl) phthalate multiple interactions ISO RGD:1318135 6480464 PPARA protein promotes the reaction [Diethylhexyl Phthalate results in increased expression of HIBCH mRNA] CTD PMID:19850644 Hibch Rat bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of HIBCH mRNA CTD PMID:25181051|PMID:30816183|PMID:32528016|PMID:34947998 Hibch Rat bisphenol A increases expression ISO RGD:1318134 6480464 bisphenol A results in increased expression of HIBCH protein CTD PMID:37567409 Hibch Rat bisphenol A decreases expression ISO RGD:1318134 6480464 bisphenol A results in decreased expression of HIBCH protein CTD PMID:34186270 Hibch Rat bisphenol AF increases expression ISO RGD:1318134 6480464 bisphenol AF results in increased expression of HIBCH protein CTD PMID:34186270 Hibch Rat Bisphenol B increases expression ISO RGD:1318134 6480464 bisphenol B results in increased expression of HIBCH protein CTD PMID:34186270 Hibch Rat bisphenol F increases expression ISO RGD:1318134 6480464 bisphenol F results in increased expression of HIBCH protein CTD PMID:34186270 Hibch Rat Brodifacoum increases expression EXP 6480464 bromfenacoum results in increased expression of HIBCH protein CTD PMID:28903499 Hibch Rat buspirone increases expression EXP 6480464 Buspirone results in increased expression of HIBCH mRNA CTD PMID:24136188 Hibch Rat cadmium atom increases oxidation ISO RGD:1318135 6480464 Cadmium results in increased oxidation of HIBCH protein CTD PMID:24496640 Hibch Rat cadmium atom multiple interactions ISO RGD:1318134 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of HIBCH more ... CTD PMID:35301059 Hibch Rat cadmium dichloride multiple interactions ISO RGD:1318134 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of HIBCH more ... CTD PMID:35301059 Hibch Rat calcitriol multiple interactions ISO RGD:1318134 6480464 [Testosterone co-treated with Calcitriol] results in increased expression of HIBCH mRNA CTD PMID:21592394 Hibch Rat calcitriol increases expression ISO RGD:1318134 6480464 Calcitriol results in increased expression of HIBCH mRNA CTD PMID:21592394 Hibch Rat chlorpyrifos decreases expression ISO RGD:1318135 6480464 Chlorpyrifos results in decreased expression of HIBCH mRNA CTD PMID:37019170 Hibch Rat cisplatin increases expression ISO RGD:1318134 6480464 Cisplatin results in increased expression of HIBCH mRNA CTD PMID:27392435 Hibch Rat cisplatin multiple interactions ISO RGD:1318134 6480464 [Cisplatin co-treated with jinfukang] results in increased expression of HIBCH mRNA CTD PMID:27392435 Hibch Rat clofibrate increases expression EXP 6480464 Clofibrate results in increased expression of HIBCH mRNA CTD PMID:12851107 Hibch Rat cobalt dichloride decreases expression ISO RGD:1318134 6480464 cobaltous chloride results in decreased expression of HIBCH mRNA CTD PMID:19376846 Hibch Rat copper atom multiple interactions ISO RGD:1318134 6480464 [NSC 689534 binds to Copper] which results in decreased expression of HIBCH mRNA CTD PMID:20971185 Hibch Rat copper(0) multiple interactions ISO RGD:1318134 6480464 [NSC 689534 binds to Copper] which results in decreased expression of HIBCH mRNA CTD PMID:20971185 Hibch Rat cyclosporin A decreases expression ISO RGD:1318134 6480464 Cyclosporine results in decreased expression of HIBCH mRNA CTD PMID:20106945|PMID:25562108 Hibch Rat D-glucose decreases secretion ISO RGD:1318134 6480464 Glucose deficiency results in decreased secretion of HIBCH protein CTD PMID:24802182 Hibch Rat Dibutyl phosphate affects expression ISO RGD:1318134 6480464 di-n-butylphosphoric acid affects the expression of HIBCH mRNA CTD PMID:37042841 Hibch Rat dibutyl phthalate decreases expression EXP 6480464 Dibutyl Phthalate results in decreased expression of HIBCH mRNA CTD PMID:21266533 Hibch Rat dicrotophos decreases expression ISO RGD:1318134 6480464 dicrotophos results in decreased expression of HIBCH mRNA CTD PMID:28302478 Hibch Rat finasteride increases expression EXP 6480464 Finasteride results in increased expression of HIBCH mRNA CTD PMID:24136188 Hibch Rat flutamide increases expression EXP 6480464 Flutamide results in increased expression of HIBCH mRNA CTD PMID:24136188 Hibch Rat folic acid multiple interactions ISO RGD:1318135 6480464 [1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of HIBCH mRNA CTD PMID:22206623 Hibch Rat furan increases expression EXP 6480464 furan results in increased expression of HIBCH mRNA CTD PMID:25539665|PMID:26194646 Hibch Rat gentamycin decreases expression EXP 6480464 Gentamicins results in decreased expression of HIBCH mRNA CTD PMID:33387578 Hibch Rat glafenine decreases expression EXP 6480464 Glafenine results in decreased expression of HIBCH mRNA CTD PMID:24136188 Hibch Rat glucose decreases secretion ISO RGD:1318134 6480464 Glucose deficiency results in decreased secretion of HIBCH protein CTD PMID:24802182 Hibch Rat glyphosate increases expression ISO RGD:1318135 6480464 Glyphosate results in increased expression of HIBCH protein CTD PMID:36173347 Hibch Rat indometacin decreases expression EXP 6480464 Indomethacin results in decreased expression of HIBCH mRNA CTD PMID:36868495 Hibch Rat inulin multiple interactions ISO RGD:1318135 6480464 [perfluorooctane sulfonic acid co-treated with Inulin] results in increased expression of HIBCH mRNA CTD PMID:36331819 Hibch Rat isoflavones increases expression ISO RGD:1318134 6480464 Isoflavones results in increased expression of HIBCH mRNA CTD PMID:17374662 Hibch Rat isotretinoin decreases expression ISO RGD:1318134 6480464 Isotretinoin results in decreased expression of HIBCH mRNA CTD PMID:20436886 Hibch Rat ivermectin decreases expression ISO RGD:1318134 6480464 Ivermectin results in decreased expression of HIBCH protein CTD PMID:32959892 Hibch Rat ketamine decreases expression EXP 6480464 Ketamine results in decreased expression of HIBCH mRNA CTD PMID:20080153 Hibch Rat kojic acid decreases expression ISO RGD:1318134 6480464 kojic acid results in decreased expression of HIBCH mRNA CTD PMID:16595896 Hibch Rat leflunomide increases expression EXP 6480464 leflunomide results in increased expression of HIBCH mRNA CTD PMID:24136188 Hibch Rat methacrylyl-CoA increases abundance ISO RGD:1318134 6480464 HIBCH gene mutant form results in increased abundance of methacrylyl-coenzyme A CTD PMID:25125611 Hibch Rat methapyrilene decreases expression EXP 6480464 Methapyrilene results in decreased expression of HIBCH mRNA; Methapyrilene results in decreased expression of HIBCH more ... CTD PMID:30467583 Hibch Rat methotrexate increases expression ISO RGD:1318134 6480464 Methotrexate results in increased expression of HIBCH mRNA CTD PMID:17400583 Hibch Rat Muraglitazar increases expression EXP 6480464 muraglitazar results in increased expression of HIBCH mRNA CTD PMID:21515302 Hibch Rat nefazodone increases expression EXP 6480464 nefazodone results in increased expression of HIBCH mRNA CTD PMID:24136188 Hibch Rat nimesulide increases expression EXP 6480464 nimesulide results in increased expression of HIBCH mRNA CTD PMID:24136188 Hibch Rat okadaic acid decreases expression ISO RGD:1318134 6480464 Okadaic Acid results in decreased expression of HIBCH mRNA CTD PMID:38832940 Hibch Rat paracetamol affects expression ISO RGD:1318135 6480464 Acetaminophen affects the expression of HIBCH mRNA CTD PMID:17562736 Hibch Rat paracetamol decreases expression EXP 6480464 Acetaminophen results in decreased expression of HIBCH mRNA CTD PMID:33387578 Hibch Rat paracetamol decreases expression ISO RGD:1318134 6480464 Acetaminophen results in decreased expression of HIBCH mRNA CTD PMID:29067470 Hibch Rat pentachlorophenol decreases expression ISO RGD:1318135 6480464 Pentachlorophenol results in decreased expression of HIBCH mRNA CTD PMID:23892564 Hibch Rat perfluorooctane-1-sulfonic acid multiple interactions ISO RGD:1318135 6480464 [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of HIBCH mRNA; [perfluorooctane sulfonic more ... CTD PMID:36331819 Hibch Rat perfluorooctanoic acid increases expression ISO RGD:1318134 6480464 perfluorooctanoic acid results in increased expression of HIBCH protein CTD PMID:26879310 Hibch Rat PhIP decreases expression EXP 6480464 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased expression of HIBCH mRNA CTD PMID:33945839 Hibch Rat piperonyl butoxide increases expression EXP 6480464 Piperonyl Butoxide results in increased expression of HIBCH mRNA CTD PMID:22484513 Hibch Rat pirinixic acid decreases expression ISO RGD:1318135 6480464 pirinixic acid results in decreased expression of HIBCH mRNA CTD PMID:18445702 Hibch Rat pirinixic acid increases expression ISO RGD:1318135 6480464 pirinixic acid results in increased expression of HIBCH mRNA CTD PMID:18301758|PMID:23811191 Hibch Rat pirinixic acid increases expression EXP 6480464 pirinixic acid results in increased expression of HIBCH mRNA CTD PMID:22484513 Hibch Rat potassium chromate multiple interactions ISO RGD:1318134 6480464 [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of HIBCH mRNA CTD PMID:22079256 Hibch Rat potassium chromate decreases expression ISO RGD:1318134 6480464 potassium chromate(VI) results in decreased expression of HIBCH mRNA CTD PMID:22079256 Hibch Rat progesterone multiple interactions ISO RGD:1318134 6480464 [Estradiol co-treated with Progesterone] results in increased expression of HIBCH mRNA CTD PMID:20660070 Hibch Rat quercetin decreases expression ISO RGD:1318134 6480464 Quercetin results in decreased expression of HIBCH mRNA CTD PMID:21632981 Hibch Rat resveratrol multiple interactions ISO RGD:1318134 6480464 [Plant Extracts co-treated with Resveratrol] results in increased expression of HIBCH mRNA CTD PMID:23557933 Hibch Rat rotenone increases expression EXP 6480464 Rotenone results in increased expression of HIBCH mRNA; Rotenone results in increased expression of HIBCH more ... CTD PMID:28374803|PMID:35544339 Hibch Rat SB 431542 multiple interactions ISO RGD:1318134 6480464 [LDN 193189 co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide co-treated with FGF2 protein] results in increased expression of HIBCH more ... CTD PMID:37664457 Hibch Rat sodium arsenite decreases expression ISO RGD:1318135 6480464 sodium arsenite results in decreased expression of HIBCH protein CTD PMID:29044176 Hibch Rat sulforaphane increases expression ISO RGD:1318135 6480464 sulforaphane results in increased expression of HIBCH mRNA CTD PMID:30529165 Hibch Rat sunitinib decreases expression ISO RGD:1318134 6480464 Sunitinib results in decreased expression of HIBCH mRNA CTD PMID:31533062 Hibch Rat Tesaglitazar increases expression EXP 6480464 tesaglitazar results in increased expression of HIBCH mRNA CTD PMID:21515302 Hibch Rat testosterone multiple interactions ISO RGD:1318134 6480464 [Testosterone co-treated with Calcitriol] results in increased expression of HIBCH mRNA CTD PMID:21592394 Hibch Rat testosterone increases expression ISO RGD:1318134 6480464 Testosterone results in increased expression of HIBCH mRNA CTD PMID:21592394 Hibch Rat testosterone enanthate affects expression ISO RGD:1318134 6480464 testosterone enanthate affects the expression of HIBCH mRNA CTD PMID:17440010 Hibch Rat tetrachloromethane decreases expression ISO RGD:1318135 6480464 Carbon Tetrachloride results in decreased expression of HIBCH mRNA CTD PMID:27339419|PMID:31919559 Hibch Rat tetrahydropalmatine increases expression ISO RGD:1318134 6480464 tetrahydropalmatine results in increased expression of HIBCH protein CTD PMID:20109541 Hibch Rat thioacetamide decreases expression EXP 6480464 Thioacetamide results in decreased expression of HIBCH mRNA CTD PMID:34492290 Hibch Rat titanium dioxide decreases expression ISO RGD:1318135 6480464 titanium dioxide results in decreased expression of HIBCH mRNA CTD PMID:23557971 Hibch Rat triphenyl phosphate increases expression EXP 6480464 triphenyl phosphate results in increased expression of HIBCH mRNA CTD PMID:30589522 Hibch Rat triphenyl phosphate affects expression ISO RGD:1318134 6480464 triphenyl phosphate affects the expression of HIBCH mRNA CTD PMID:37042841 Hibch Rat triptonide decreases expression ISO RGD:1318135 6480464 triptonide results in decreased expression of HIBCH mRNA CTD PMID:33045310 Hibch Rat troglitazone increases expression ISO RGD:1318135 6480464 troglitazone results in increased expression of HIBCH protein CTD PMID:18495193 Hibch Rat troglitazone increases expression EXP 6480464 troglitazone results in increased expression of HIBCH mRNA CTD PMID:21515302 Hibch Rat valdecoxib increases expression EXP 6480464 valdecoxib results in increased expression of HIBCH mRNA CTD PMID:24136188 Hibch Rat valproic acid increases expression ISO RGD:1318134 6480464 Valproic Acid results in increased expression of HIBCH mRNA CTD PMID:23179753 Hibch Rat valproic acid affects expression ISO RGD:1318134 6480464 Valproic Acid affects the expression of HIBCH mRNA CTD PMID:25979313 Hibch Rat vorinostat increases expression ISO RGD:1318134 6480464 vorinostat results in increased expression of HIBCH mRNA CTD PMID:27188386
Imported Annotations - SMPDB
Imported Annotations - KEGG (archival)
Hibch Rat Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCr8 9 56,082,082 - 56,161,796 (-) NCBI GRCr8 mRatBN7.2 9 48,590,097 - 48,669,896 (-) NCBI mRatBN7.2 mRatBN7.2 mRatBN7.2 Ensembl 9 48,590,099 - 48,669,824 (-) Ensembl mRatBN7.2 Ensembl UTH_Rnor_SHR_Utx 9 57,131,763 - 57,211,849 (-) NCBI Rnor_SHR UTH_Rnor_SHR_Utx UTH_Rnor_SHRSP_BbbUtx_1.0 9 62,254,592 - 62,334,677 (-) NCBI Rnor_SHRSP UTH_Rnor_SHRSP_BbbUtx_1.0 UTH_Rnor_WKY_Bbb_1.0 9 60,550,578 - 60,630,667 (-) NCBI Rnor_WKY UTH_Rnor_WKY_Bbb_1.0 Rnor_6.0 9 53,446,185 - 53,526,727 (-) NCBI Rnor6.0 Rnor_6.0 rn6 Rnor6.0 Rnor_6.0 Ensembl 9 53,446,194 - 53,526,728 (-) Ensembl Rnor6.0 rn6 Rnor6.0 Rnor_5.0 9 53,112,579 - 53,193,190 (-) NCBI Rnor5.0 Rnor_5.0 rn5 Rnor5.0 RGSC_v3.4 9 45,564,702 - 45,645,252 (-) NCBI RGSC3.4 RGSC_v3.4 rn4 RGSC3.4 RGSC_v3.1 9 45,566,124 - 45,624,624 (-) NCBI Celera 9 46,259,906 - 46,339,124 (-) NCBI Celera Cytogenetic Map 9 q22 NCBI
HIBCH Human Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCh38 2 190,189,735 - 190,319,826 (-) NCBI GRCh38 GRCh38 hg38 GRCh38 GRCh38.p14 Ensembl 2 190,189,735 - 190,344,193 (-) Ensembl GRCh38 hg38 GRCh38 GRCh37 2 191,068,646 - 191,184,552 (-) NCBI GRCh37 GRCh37 hg19 GRCh37 Build 36 2 190,777,605 - 190,892,804 (-) NCBI NCBI36 Build 36 hg18 NCBI36 Build 34 2 190,894,866 - 191,010,065 NCBI Celera 2 184,664,402 - 184,779,775 (-) NCBI Celera Cytogenetic Map 2 q32.2 NCBI HuRef 2 182,929,253 - 183,044,631 (-) NCBI HuRef CHM1_1 2 191,075,217 - 191,190,581 (-) NCBI CHM1_1 T2T-CHM13v2.0 2 190,693,510 - 190,809,397 (-) NCBI T2T-CHM13v2.0
Hibch Mouse Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCm39 1 52,884,197 - 52,960,145 (+) NCBI GRCm39 GRCm39 mm39 GRCm39 Ensembl 1 52,884,088 - 52,960,145 (+) Ensembl GRCm39 Ensembl GRCm38 1 52,845,038 - 52,920,986 (+) NCBI GRCm38 GRCm38 mm10 GRCm38 GRCm38.p6 Ensembl 1 52,844,929 - 52,920,986 (+) Ensembl GRCm38 mm10 GRCm38 MGSCv37 1 52,901,890 - 52,977,704 (+) NCBI GRCm37 MGSCv37 mm9 NCBIm37 MGSCv36 1 52,789,591 - 52,865,405 (+) NCBI MGSCv36 mm8 Celera 1 53,386,006 - 53,461,488 (+) NCBI Celera Cytogenetic Map 1 C1.1 NCBI cM Map 1 26.99 NCBI
Hibch Chinchilla Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl ChiLan1.0 Ensembl NW_004955403 8,752,309 - 8,792,927 (+) Ensembl ChiLan1.0 ChiLan1.0 NW_004955403 8,752,339 - 8,796,693 (+) NCBI ChiLan1.0 ChiLan1.0
HIBCH Bonobo Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl NHGRI_mPanPan1-v2 13 92,896,951 - 93,041,587 (-) NCBI NHGRI_mPanPan1-v2 NHGRI_mPanPan1 2B 92,911,935 - 93,053,182 (-) NCBI NHGRI_mPanPan1 Mhudiblu_PPA_v0 2B 77,510,938 - 77,652,911 (-) NCBI Mhudiblu_PPA_v0 Mhudiblu_PPA_v0 panPan3 PanPan1.1 2B 195,429,787 - 195,544,564 (-) NCBI panpan1.1 PanPan1.1 panPan2
HIBCH Dog Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl CanFam3.1 37 841,385 - 943,972 (-) NCBI CanFam3.1 CanFam3.1 canFam3 CanFam3.1 CanFam3.1 Ensembl 37 841,414 - 943,941 (-) Ensembl CanFam3.1 canFam3 CanFam3.1 Dog10K_Boxer_Tasha 37 1,797,343 - 1,893,653 (-) NCBI Dog10K_Boxer_Tasha ROS_Cfam_1.0 37 735,664 - 832,314 (-) NCBI ROS_Cfam_1.0 ROS_Cfam_1.0 Ensembl 37 735,666 - 832,320 (-) Ensembl ROS_Cfam_1.0 Ensembl UMICH_Zoey_3.1 37 746,020 - 842,670 (-) NCBI UMICH_Zoey_3.1 UNSW_CanFamBas_1.0 37 713,636 - 809,463 (-) NCBI UNSW_CanFamBas_1.0 UU_Cfam_GSD_1.0 37 742,338 - 838,606 (-) NCBI UU_Cfam_GSD_1.0
Hibch Squirrel Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl HiC_Itri_2 NW_024405303 148,955,211 - 149,026,449 (-) NCBI HiC_Itri_2 SpeTri2.0 Ensembl NW_004936506 7,811,600 - 7,882,642 (+) Ensembl SpeTri2.0 SpeTri2.0 Ensembl SpeTri2.0 NW_004936506 7,811,624 - 7,882,861 (+) NCBI SpeTri2.0 SpeTri2.0 SpeTri2.0
HIBCH Pig Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl Sscrofa11.1 Ensembl 15 94,792,985 - 94,941,266 (-) Ensembl Sscrofa11.1 susScr11 Sscrofa11.1 Sscrofa11.1 15 94,795,744 - 94,941,362 (-) NCBI Sscrofa11.1 Sscrofa11.1 susScr11 Sscrofa11.1 Sscrofa10.2 15 105,964,875 - 105,973,529 (-) NCBI Sscrofa10.2 Sscrofa10.2 susScr3
HIBCH Green Monkey Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl ChlSab1.1 10 75,711,829 - 75,852,055 (-) NCBI ChlSab1.1 ChlSab1.1 chlSab2 ChlSab1.1 Ensembl 10 75,715,996 - 75,828,310 (-) Ensembl ChlSab1.1 ChlSab1.1 Ensembl chlSab2 Vero_WHO_p1.0 NW_023666040 123,643,515 - 123,757,713 (+) NCBI Vero_WHO_p1.0 Vero_WHO_p1.0
Hibch
.
Predicted Target Of
Count of predictions: 404 Count of miRNA genes: 214 Interacting mature miRNAs: 251 Transcripts: ENSRNOT00000029677, ENSRNOT00000040650 Prediction methods: Microtar, Miranda, Rnahybrid Result types: miRGate_prediction
7411571 Bw138 Body weight QTL 138 14.3 0.001 body mass (VT:0001259) body weight gain (CMO:0000420) 9 32535505 77535505 Rat 1300180 Bw14 Body weight QTL 14 3.776 body mass (VT:0001259) body weight (CMO:0000012) 9 23754024 61381613 Rat 11353957 Bmd92 Bone mineral density QTL 92 0.01 tibia mineral mass (VT:1000283) volumetric bone mineral density (CMO:0001553) 9 46114199 91114199 Rat 631680 Cm11 Cardiac mass QTL 11 3.1 0.00089 heart left ventricle mass (VT:0007031) heart left ventricle weight to body weight ratio (CMO:0000530) 9 20430519 65430519 Rat 70218 Cm28 Cardiac mass QTL 28 8.3 0.0001 heart mass (VT:0007028) heart wet weight (CMO:0000069) 9 25268044 79271759 Rat 724544 Uae9 Urinary albumin excretion QTL 9 4.5 urine albumin amount (VT:0002871) urine albumin level (CMO:0000130) 9 25268044 114175309 Rat 7207805 Bmd88 Bone mineral density QTL 88 4 femur mineral mass (VT:0010011) total volumetric bone mineral density (CMO:0001728) 9 23754024 58157242 Rat 631643 Bp120 Blood pressure QTL 120 3 0.004 arterial blood pressure trait (VT:2000000) systolic blood pressure (CMO:0000004) 9 22071200 67071200 Rat 12879506 Pur33 Proteinuria QTL 33 urine total protein amount (VT:0000032) urine total protein excretion rate (CMO:0000756) 9 44649921 89649921 Rat 731164 Uae25 Urinary albumin excretion QTL 25 3.5 0.0001 urine albumin amount (VT:0002871) urine albumin excretion rate (CMO:0000757) 9 25661188 100929786 Rat 10058949 Gmadr5 Adrenal mass QTL 5 2 0.014 adrenal gland mass (VT:0010420) both adrenal glands wet weight to body weight ratio (CMO:0002411) 9 42791513 87976209 Rat 9589133 Insul26 Insulin level QTL 26 17.96 0.001 blood insulin amount (VT:0001560) plasma insulin level (CMO:0000342) 9 8952560 53952560 Rat 631656 Bp108 Blood pressure QTL 108 5.97 0.0001 arterial blood pressure trait (VT:2000000) systolic blood pressure (CMO:0000004) 9 48598251 93598251 Rat 631211 Bw4 Body weight QTL4 5.31 retroperitoneal fat pad mass (VT:0010430) retroperitoneal fat pad weight to body weight ratio (CMO:0000635) 9 5109826 50109826 Rat 7411609 Foco16 Food consumption QTL 16 25.6 0.001 eating behavior trait (VT:0001431) feed conversion ratio (CMO:0001312) 9 8952560 53952560 Rat 8662828 Vetf6 Vascular elastic tissue fragility QTL 6 3.9 artery integrity trait (VT:0010639) patent ductus arteriosus score (CMO:0002566) 9 36962359 92058970 Rat 61352 Bp34 Blood pressure QTL 34 5 arterial blood pressure trait (VT:2000000) systolic blood pressure (CMO:0000004) 9 42495343 79271511 Rat 6903937 Bp356 Blood pressure QTL 356 0.001 arterial blood pressure trait (VT:2000000) systolic blood pressure (CMO:0000004) 9 47902208 52283252 Rat 1598834 Memor11 Memory QTL 11 2.5 exploratory behavior trait (VT:0010471) average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674) 9 36962359 77814038 Rat 70186 Niddm26 Non-insulin dependent diabetes mellitus QTL 26 3.87 blood glucose amount (VT:0000188) blood glucose level area under curve (AUC) (CMO:0000350) 9 22071169 86369743 Rat 7207814 Bmd91 Bone mineral density QTL 91 3.5 femur size trait (VT:1000369) femoral neck cross-sectional area (CMO:0001697) 9 23754144 83851531 Rat 6903941 Pur31 Proteinuria QTL 31 0.036 urine total protein amount (VT:0000032) urine protein excretion rate (CMO:0000759) 9 40194188 85194188 Rat 2290450 Scl57 Serum cholesterol level QTL 57 4.15 blood cholesterol amount (VT:0000180) plasma total cholesterol level (CMO:0000585) 9 36962359 95410867 Rat 11353949 Bp393 Blood pressure QTL 393 arterial blood pressure trait (VT:2000000) systolic blood pressure (CMO:0000004) 9 40194188 85194188 Rat 11353951 Bp394 Blood pressure QTL 394 arterial blood pressure trait (VT:2000000) systolic blood pressure (CMO:0000004) 9 44649921 89649921 Rat 10054125 Srcrt7 Stress Responsive Cort QTL 7 3.33 0.0011 blood corticosterone amount (VT:0005345) plasma corticosterone level (CMO:0001173) 9 1 87073594 Rat 11353947 Bp392 Blood pressure QTL 392 arterial blood pressure trait (VT:2000000) systolic blood pressure (CMO:0000004) 9 7283252 52283252 Rat 1331757 Cdexp1 CD45RC expression in CD8 T cells QTL 1 4.3 CD8-positive T cell quantity (VT:0008077) blood CD45RC(high) CD8 T cell count to CD45RC(low) CD8 T cell count ratio (CMO:0001990) 9 1024537 67509080 Rat 7411656 Foco26 Food consumption QTL 26 9.8 0.001 eating behavior trait (VT:0001431) feed conversion ratio (CMO:0001312) 9 32535505 77535505 Rat 1598823 Memor16 Memory QTL 16 1.9 exploratory behavior trait (VT:0010471) difference between time of physical contact/close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678) 9 22133322 49968732 Rat 1641894 Alcrsp12 Alcohol response QTL 12 response to alcohol trait (VT:0010489) brain neurotensin receptor 1 density (CMO:0002068) 9 27468639 72468639 Rat
Click on a value in the shaded box below the category label to view a detailed expression data table for that system.
alimentary part of gastrointestinal system
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Ensembl Acc Id:
ENSRNOT00000029677 ⟹ ENSRNOP00000032041
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source mRatBN7.2 Ensembl 9 48,590,101 - 48,669,798 (-) Ensembl Rnor_6.0 Ensembl 9 53,446,593 - 53,526,728 (-) Ensembl
Ensembl Acc Id:
ENSRNOT00000040650 ⟹ ENSRNOP00000046370
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source mRatBN7.2 Ensembl 9 48,590,099 - 48,669,824 (-) Ensembl Rnor_6.0 Ensembl 9 53,446,194 - 53,526,641 (-) Ensembl
Ensembl Acc Id:
ENSRNOT00000111639 ⟹ ENSRNOP00000078527
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source mRatBN7.2 Ensembl 9 48,590,101 - 48,663,172 (-) Ensembl
Ensembl Acc Id:
ENSRNOT00000116077 ⟹ ENSRNOP00000084082
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source mRatBN7.2 Ensembl 9 48,590,101 - 48,656,597 (-) Ensembl
RefSeq Acc Id:
NM_001013112 ⟹ NP_001013130
RefSeq Status:
VALIDATED
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 9 56,082,082 - 56,161,796 (-) NCBI mRatBN7.2 9 48,590,097 - 48,669,815 (-) NCBI Rnor_6.0 9 53,446,185 - 53,526,641 (-) NCBI Rnor_5.0 9 53,112,579 - 53,193,190 (-) NCBI RGSC_v3.4 9 45,564,702 - 45,645,252 (-) RGD Celera 9 46,259,906 - 46,339,124 (-) RGD
Sequence:
GTCAGTGACCCTGGCTCTTCTAGGTTCTGGTCGGCGGTGGGCGGGTCTGAGAAGTGCAGGTGGAGTTGCTACGTTCTGCTAATTCATCTCTAGGGTTTTAGGCCATGGGGCAGCAGTTTGTGTGGCGG
hide sequence
RefSeq Acc Id:
NM_001398668 ⟹ NP_001385597
RefSeq Status:
VALIDATED
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 9 56,082,082 - 56,161,796 (-) NCBI mRatBN7.2 9 48,590,097 - 48,669,815 (-) NCBI
RefSeq Acc Id:
XM_039083288 ⟹ XP_038939216
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 9 56,082,082 - 56,148,344 (-) NCBI mRatBN7.2 9 48,590,121 - 48,656,290 (-) NCBI
RefSeq Acc Id:
XM_039083289 ⟹ XP_038939217
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 9 56,082,082 - 56,151,645 (-) NCBI mRatBN7.2 9 48,590,121 - 48,662,740 (-) NCBI
RefSeq Acc Id:
XM_063266936 ⟹ XP_063123006
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 9 56,082,082 - 56,148,344 (-) NCBI
RefSeq Acc Id:
XM_063266937 ⟹ XP_063123007
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 9 56,088,967 - 56,148,344 (-) NCBI
RefSeq Acc Id:
XM_063266938 ⟹ XP_063123008
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 9 56,082,667 - 56,148,344 (-) NCBI
RefSeq Acc Id:
XM_063266939 ⟹ XP_063123009
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 9 56,092,615 - 56,161,792 (-) NCBI
RefSeq Acc Id:
NP_001013130 ⟸ NM_001013112
- Peptide Label:
isoform 2
- UniProtKB:
Q5XIE6 (UniProtKB/Swiss-Prot)
- Sequence:
MGQQFVWRLQSRFSSIRRASVILQHLRMSKHTETAEVLLERRGCAGVITLNRPKLLNALSLNMIRQIYPQLKKWERDPDTFLIIIKGAGGKAFCAGGDIKALSEAKKAGQTLSQDLFREEYILNNAIA
hide sequence
Ensembl Acc Id:
ENSRNOP00000032041 ⟸ ENSRNOT00000029677
Ensembl Acc Id:
ENSRNOP00000046370 ⟸ ENSRNOT00000040650
RefSeq Acc Id:
XP_038939217 ⟸ XM_039083289
- Peptide Label:
isoform X2
- UniProtKB:
A0A8I5ZL23 (UniProtKB/TrEMBL)
RefSeq Acc Id:
XP_038939216 ⟸ XM_039083288
- Peptide Label:
isoform X1
- UniProtKB:
A0A8I5ZL23 (UniProtKB/TrEMBL), A0A8I6A0J8 (UniProtKB/TrEMBL)
Ensembl Acc Id:
ENSRNOP00000084082 ⟸ ENSRNOT00000116077
Ensembl Acc Id:
ENSRNOP00000078527 ⟸ ENSRNOT00000111639
RefSeq Acc Id:
NP_001385597 ⟸ NM_001398668
- Peptide Label:
isoform 1
- UniProtKB:
Q5XIE6 (UniProtKB/Swiss-Prot), A0A8I5ZL23 (UniProtKB/TrEMBL), A6INV5 (UniProtKB/TrEMBL)
RefSeq Acc Id:
XP_063123006 ⟸ XM_063266936
- Peptide Label:
isoform X3
RefSeq Acc Id:
XP_063123008 ⟸ XM_063266938
- Peptide Label:
isoform X4
RefSeq Acc Id:
XP_063123007 ⟸ XM_063266937
- Peptide Label:
isoform X4
RefSeq Acc Id:
XP_063123009 ⟸ XM_063266939
- Peptide Label:
isoform X5
RGD ID: 13696652 Promoter ID: EPDNEW_R7176 Type: initiation region Name: Hibch_1 Description: 3-hydroxyisobutyryl-CoA hydrolase SO ACC ID: SO:0000170 Source: EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/ ) Experiment Methods: Single-end sequencing. Position: Rat Assembly Chr Position (strand) Source Rnor_6.0 9 53,526,668 - 53,526,728 EPDNEW
Date
Current Symbol
Current Name
Previous Symbol
Previous Name
Description
Reference
Status
2011-08-02
Hibch
3-hydroxyisobutyryl-CoA hydrolase
Hibch
3-hydroxyisobutyryl-Coenzyme A hydrolase
Nomenclature updated to reflect human and mouse nomenclature
1299863 APPROVED
2005-12-06
Hibch
3-hydroxyisobutyryl-Coenzyme A hydrolase
Hibch_predicted
3-hydroxyisobutyryl-Coenzyme A hydrolase (predicted)
Symbol and Name updated
1559027 APPROVED
2005-01-12
Hibch_predicted
3-hydroxyisobutyryl-Coenzyme A hydrolase (predicted)
Symbol and Name status set to approved
70820 APPROVED
