Bp356 QTL Report (Rattus norvegicus) - Rat Genome Database

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QTL: Bp356 (Blood pressure QTL 356) Rattus norvegicus

Symbol: Bp356
Name: Blood pressure QTL 356
RGD ID: 6903937
Trait: arterial blood pressure trait   (VT:2000000)    
Measurement Type: systolic blood pressure   (CMO:0000004)    
LOD Score: Not Available
P Value: 0.001
Variance: Not Available
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2947,902,208 - 52,283,252RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.0952,686,874 - 57,216,771RGD_MAPPER_PIPELINERnor6.0
Rnor_5.0952,352,690 - 97,352,690RGDRnor5.0
RGSC_v3.4944,842,118 - 89,842,118RGDRGSC3.4
Cross Type: Not Available
Strains Crossed: SS.SHR-(D9Mco72-D9Mco105)/Mco 
JBrowse: View Region in Genome Browser (JBrowse)
Model



Disease Annotations     Click to see Annotation Detail View
Hypotension  (IAGP)

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
Experimental Data Annotations     Click to see Annotation Detail View

Clinical Measurement

Experimental Condition

Measurement Method

Vertebrate Trait

Rat Strain

References

References - curated
# Reference Title Reference Citation
1. Refined mapping of blood pressure quantitative trait loci using congenic strains developed from two genetically hypertensive rat models. Kumarasamy S, etal., Hypertens Res. 2011 Dec;34(12):1263-70. doi: 10.1038/hr.2011.116. Epub 2011 Aug 4.
Related QTLs

Related QTL Description Reference
Bp333 sub_region RGD:6903249


Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
70882Nab1Ngfi-A binding protein 194905357949093078Rat
70994Myo1bmyosin Ib94969004349852373Rat
2707Glsglutaminase94934461649416900Rat
620180Slc40a1solute carrier family 40 member 194803352648053876Rat
3115Mstnmyostatin94845398248458809Rat
1305575Osgepl1O-sialoglycoprotein endopeptidase-like 194821499548229440Rat
3771Stat1signal transducer and activator of transcription 194941956149459969Rat
1306332Asnsd1asparagine synthetase domain containing 194812680248139073Rat
1305747Stat4signal transducer and activator of transcription 494947266049588540Rat
1306658Nabp1nucleic acid binding protein 195009855250133982Rat
1306071Inpp1inositol polyphosphate-1-phosphatase94868803748717793Rat
1308392Hibch3-hydroxyisobutyryl-CoA hydrolase94859009748669896Rat
2300146Ormdl1ORMDL sphingolipid biosynthesis regulator 194824336548253316Rat
1308839Tmeff2transmembrane protein with EGF-like and two follistatin-like domains 295044555050733482Rat
1561618Rpl23-ps2ribosomal protein L23,pseudogene 295014337250154483Rat
1560421Nemp2nuclear envelope integral membrane protein 294886125248880565Rat
1562317Mfsd6major facilitator superfamily domain containing 694877317148858471Rat
1359511Pms1PMS1 homolog 1, mismatch repair system component94822940348340237Rat
1359345Cavin2caveolae associated protein 295030207950314096Rat
1561071Ankarankyrin and armadillo repeat containing94814153448215400Rat
1564869Wdr75WD repeat domain 7594790316647933399Rat
1565371Bnip3-ps1BCL2 interacting protein 3, pseudogene 194876280448764417Rat
1591348Mettl6-ps1methyltransferase like 6, pseudogene 195151474651515605Rat
1595308Smc6-ps1structural maintenance of chromosomes 6, pseudogene 194852114648522274Rat
1597774LOC685108similar to proteolipid protein 294807677548077809Rat
1596493LOC685203hypothetical protein LOC68520394853914048584882Rat
1596442Pgap2-ps2post-GPI attachment to proteins 2, pseudogene 294874157148760802Rat
2323350Got2-ps3glutamic-oxaloacetic transaminase 2, pseudogene 394799538648000701Rat
2323836Ccdc126-ps1coiled-coil domain containing 126, pseudogene 195124491251245507Rat
6486560Srsf7-ps4serine and arginine rich splicing factor 7, pseudogene 494858786548589638Rat
6487672Dppa3-ps5developmental pluripotency-associated 3, pseudogene 594888215848883075Rat
6501804Rpl12-ps4ribosomal protein L12, pseudogene 494999652149997143Rat
7640284Aasdhppt-ps1aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase, pseudogene 195073524950746852Rat
7543919Npm1-ps7nucleophosmin 1, pseudogene 795056244350587615Rat
9346435LOC103690550uncharacterized LOC10369055094968777449689862Rat
11362092LOC108351929uncharacterized LOC10835192995048922750559755Rat
11474459LOC108352026high mobility group protein B1 pseudogene94921481949215542Rat
11436408LOC10835192460S ribosomal protein L37 pseudogene94828521248287989Rat
11444870LOC108351925glyceraldehyde-3-phosphate dehydrogenase pseudogene94927239849273479Rat
11446793LOC10835202740S ribosomal protein S28-like95151597051516251Rat
11365277LOC108351926thymosin beta-10 pseudogene94997482349975501Rat
41234631LOC120094970U6 spliceosomal RNA95042574950425855Rat
41174017AsdurfASNSD1 upstream open reading frame94812677648139054Rat
41096178Rps7-ps13ribosomal protein S7, pseudogene 1395087190650872667Rat
41180480LOC120094929small nucleolar RNA SNORA1795209028852090429Rat
41107517LOC120094903small nucleolar RNA SNORA4895032157750321728Rat
41015968LOC120094683uncharacterized LOC12009468395017283950187261Rat
41298570LOC120094923small nucleolar RNA SNORA1794839195548392087Rat
41300716LOC120094969U4 spliceosomal RNA95031778850317913Rat
41074009NEWGENE_40934091transfer RNA alanine (anticodon AGC)95010982550109905Rat

Markers in Region
The following Markers overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolExpected SizeChrStartStopSpeciesMatch
10658D9Wox1518494941569249415876Ratregion
36582D9Rat2117294920974149209920Ratregion
35010D9Rat2416894920978849209967Ratregion
35833D9Rat2014195006217650062324Ratregion
39872D9Rat11920895107333651073542Ratregion
38716D9Rat6014794803593448036057Ratregion
40304D9Rat12114095099769550997861Ratregion
39362D9Rat9220494996854649968732Ratregion
1638988D9Got23915694929512749295283Ratregion
2302881D9Mco7324895068715250687400Ratregion
2302905D9Mco7220794790220847902417Ratregion
7206036Bnip322294876389648764118Ratregion
5036203D1Ncl318594933205249332237Ratregion
7206688UniSTS:54753922495030327950303503Ratregion
5034490BF41582514295057023150570373Ratregion
5026542RH13260917094909284849093018Ratregion
5034724BF39162112095043516150435281Ratregion
5032633RH13472620994871755148717760Ratregion
5028069U2729515194871762148717772Ratregion
5028079U4700810094909028249090382Ratregion
5054883RH14347914394939532149395464Ratregion
5050180RH13390820495030250350302705Ratregion
5053295RH14256617495066394950664123Ratregion
5043414RH13001219194793308547933276Ratregion
5049298RH13340015094858878748588937Ratregion
5046912RH13202621094886132348861533Ratregion
5049588RH13356720094813875348138953Ratregion
5042354RH12938619794803386748034064Ratregion
5043276RH12993318294942041649420598Ratregion
5072522RH13689818094803470648034886Ratregion
5076298RH13909522394939544049395663Ratregion
5076874RH13942923994858721848587457Ratregion
5077804RH13996918394941886449419047Ratregion
5079692RH14114818794941963049419817Ratregion
5073104RH13724018594939238149392566Ratregion
5071472RH13510218094934395249344132Ratregion
5067858AU04749317295110741251107584Ratregion
5067974AU04742526794903512749035389Ratregion
5068006AU04740616995069253150692695Ratregion
5064676BF39954921295043383350434045Ratregion
5084132AA84864613194909195449092085Ratregion
5084678AI17124115894823315548233547Ratregion
5083507AI54748218594824892548249110Ratregion
5504346D11S3330095122376851224061Ratregion
5499561AI8525619695013848050138576Ratregion
5501782MARC_12193-12194:1004713732:141594906312949063544Ratregion
5502335RH12454922394985184049852063Ratregion
5502790GDF819094845411048454300Ratregion
5502885Gls86494941458549415449Ratregion
6903883D9Mco10323795047329250473531Ratregion
6903886D9Mco10420095217623152176433Ratregion
6903888D9Mco10521395228303952283252Ratregion
Position Markers

Flank 1: (D9Mco72)
Rat AssemblyChrPosition (strand)Source
mRatBN7.2947,902,208 - 47,902,417 (+)MAPPER
Rnor_6.0952,686,874 - 52,687,080NCBI
Rnor_5.0952,352,690 - 52,352,896UniSTS
RGSC_v3.4944,842,118 - 44,842,324UniSTS
Celera945,571,224 - 45,571,428UniSTS
Cytogenetic Map9 RGD
Flank 2: (D9Mco105)
Rat AssemblyChrPosition (strand)Source
mRatBN7.2952,283,039 - 52,283,252 (+)MAPPER
Rnor_6.0957,216,559 - 57,216,771NCBI
Cytogenetic Map9 RGD


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
10054125Srcrt7Stress Responsive Cort QTL 73.330.0011blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)9187073594Rat
1331757Cdexp1CD45RC expression in CD8 T cells QTL 14.3CD8-positive T cell quantity (VT:0008077)blood CD45RC(high) CD8 T cell count to CD45RC(low) CD8 T cell count ratio (CMO:0001990)9102453767509080Rat
631211Bw4Body weight QTL45.31retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)9510982650109826Rat
11353947Bp392Blood pressure QTL 392arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)9728325252283252Rat
9589133Insul26Insulin level QTL 2617.960.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)9895256053952560Rat
7411609Foco16Food consumption QTL 1625.60.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)9895256053952560Rat
631680Cm11Cardiac mass QTL 113.10.00089heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)92043051965430519Rat
70186Niddm26Non-insulin dependent diabetes mellitus QTL 263.87blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)92207116986369743Rat
631643Bp120Blood pressure QTL 12030.004arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)92207120067071200Rat
1598823Memor16Memory QTL 161.9exploratory behavior trait (VT:0010471)difference between time of physical contact/close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)92213332249968732Rat
7207805Bmd88Bone mineral density QTL 884femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)92375402458157242Rat
1300180Bw14Body weight QTL 143.776body mass (VT:0001259)body weight (CMO:0000012)92375402461381613Rat
7207814Bmd91Bone mineral density QTL 913.5femur size trait (VT:1000369)femoral neck cross-sectional area (CMO:0001697)92375414483851531Rat
70218Cm28Cardiac mass QTL 288.30.0001heart mass (VT:0007028)heart wet weight (CMO:0000069)92526804479271759Rat
724544Uae9Urinary albumin excretion QTL 94.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)925268044114175309Rat
731164Uae25Urinary albumin excretion QTL 253.50.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)925661188100929786Rat
1641894Alcrsp12Alcohol response QTL 12response to alcohol trait (VT:0010489)brain neurotensin receptor 1 density (CMO:0002068)92746863972468639Rat
7411656Foco26Food consumption QTL 269.80.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)93253550577535505Rat
7411571Bw138Body weight QTL 13814.30.001body mass (VT:0001259)body weight gain (CMO:0000420)93253550577535505Rat
1598834Memor11Memory QTL 112.5exploratory behavior trait (VT:0010471)average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)93696235977814038Rat
8662828Vetf6Vascular elastic tissue fragility QTL 63.9artery integrity trait (VT:0010639)patent ductus arteriosus score (CMO:0002566)93696235992058970Rat
2290450Scl57Serum cholesterol level QTL 574.15blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)93696235995410867Rat
6903941Pur31Proteinuria QTL 310.036total urine protein amount (VT:0000032)urine protein excretion rate (CMO:0000759)94019418885194188Rat
11353949Bp393Blood pressure QTL 393arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)94019418885194188Rat
61352Bp34Blood pressure QTL 345arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)94249534379271511Rat
10058949Gmadr5Adrenal mass QTL 520.014adrenal gland mass (VT:0010420)both adrenal glands wet weight to body weight ratio (CMO:0002411)94279151387976209Rat
11353951Bp394Blood pressure QTL 394arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)94464992189649921Rat
12879506Pur33Proteinuria QTL 33total urine protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)94464992189649921Rat
11353957Bmd92Bone mineral density QTL 920.01tibia mineral mass (VT:1000283)volumetric bone mineral density (CMO:0001553)94611419991114199Rat
6903937Bp356Blood pressure QTL 3560.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)94790220852283252Rat
631656Bp108Blood pressure QTL 1085.970.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)94859825193598251Rat
1598849Memor17Memory QTL 172.2exploratory behavior trait (VT:0010471)difference between time of physical contact/close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)94996854671098346Rat


Additional Information

RGD Curation Notes
Note Type Note Reference
qtl_general this region spans 2.05 Mb 6903249
qtl_general measurement method: animals were on 0.3% NaCl diet, at 40-42 of age they were on 2% NaCl diet; systolic blood pressure was measured by tail-cuff method on days 25-28 of high salt regimen; 4 days after this telemetric probes were implanted and blood pressure measured after recovery 6903249
qtl_general this region does not effect urine protein excretion 6903249