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Gene: Ptov1 (PTOV1, extended AT-hook containing adaptor protein) Rattus norvegicus

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Symbol:

Ptov1

Name:

PTOV1, extended AT-hook containing adaptor protein

RGD ID:

1306977

Description:

Predicted to be involved in positive regulation of transcription by RNA polymerase II. Predicted to be located in nucleoplasm. Predicted to be part of transcription regulator complex. Orthologous to human PTOV1 (PTOV1 extended AT-hook containing adaptor protein); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,4,6-trinitrotoluene.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

LOC292888; MGC94482; prostate tumor over expressed gene 1; prostate tumor overexpressed 1; prostate tumor-overexpressed gene 1 protein homolog

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	104,483,553 - 104,496,161 (-)	NCBI		GRCr8
mRatBN7.2	1	95,347,065 - 95,354,514 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	95,347,068 - 95,353,613 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	1	100,732,451 - 100,738,997 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	109,205,116 - 109,211,662 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	102,495,525 - 102,502,071 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	100,859,346 - 100,866,917 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	100,859,349 - 100,865,894 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	1	101,923,967 - 101,931,540 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	1	95,335,898 - 95,342,444 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	1	95,414,009 - 95,420,555 (-)	NCBI
Celera	1	89,608,793 - 89,615,339 (-)	NCBI		Celera
Cytogenetic Map	1	q22	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Ptov1	Rat	developmental and epileptic encephalopathy 12		ISO	PTOV1 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Developmental and epileptic encephalopathy and 12	ClinVar	PMID:27066586 more ...
Ptov1	Rat	long QT syndrome		ISO	PTOV1 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Long QT syndrome	ClinVar	PMID:26132555

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Ptov1	Rat	Disease Progression		ISO	PTOV1 (Homo sapiens)	11554173	CTD Direct Evidence: marker/mechanism	CTD	PMID:21364753
Ptov1	Rat	Stomach Neoplasms		ISO	PTOV1 (Homo sapiens)	11554173	CTD Direct Evidence: marker/mechanism	CTD	PMID:21364753

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Ptov1	Rat	1,2-dimethylhydrazine	increases expression	ISO	Ptov1 (Mus musculus)	6480464	1 and 2-Dimethylhydrazine results in increased expression of PTOV1 mRNA	CTD	PMID:22206623
Ptov1	Rat	1,2-dimethylhydrazine	multiple interactions	ISO	Ptov1 (Mus musculus)	6480464	Folic Acid inhibits the reaction [1 and 2-Dimethylhydrazine results in increased expression of PTOV1 mRNA]	CTD	PMID:22206623
Ptov1	Rat	17alpha-ethynylestradiol	multiple interactions	ISO	Ptov1 (Mus musculus)	6480464	[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of PTOV1 mRNA	CTD	PMID:17942748
Ptov1	Rat	17alpha-ethynylestradiol	affects expression	EXP		6480464	Ethinyl Estradiol affects the expression of PTOV1 mRNA	CTD	PMID:26865667
Ptov1	Rat	17beta-hydroxy-17-methylestra-4,9,11-trien-3-one	increases expression	ISO	PTOV1 (Homo sapiens)	6480464	Metribolone results in increased expression of PTOV1 mRNA	CTD	PMID:17010196
Ptov1	Rat	2,3,7,8-tetrachlorodibenzodioxine	multiple interactions	ISO	Ptov1 (Mus musculus)	6480464	[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of PTOV1 mRNA	CTD	PMID:17942748
Ptov1	Rat	2,3,7,8-tetrachlorodibenzodioxine	increases expression	EXP		6480464	Tetrachlorodibenzodioxin results in increased expression of PTOV1 mRNA	CTD	PMID:34747641
Ptov1	Rat	2,3,7,8-tetrachlorodibenzodioxine	decreases expression	EXP		6480464	Tetrachlorodibenzodioxin results in decreased expression of PTOV1 mRNA	CTD	PMID:32109520
Ptov1	Rat	2,4,6-trinitrotoluene	affects expression	EXP		6480464	Trinitrotoluene affects the expression of PTOV1 mRNA	CTD	PMID:21346803
Ptov1	Rat	3H-1,2-dithiole-3-thione	increases expression	EXP		6480464	1 and 2-dithiol-3-thione results in increased expression of PTOV1 mRNA	CTD	PMID:19162173
Ptov1	Rat	4,4'-sulfonyldiphenol	decreases methylation	ISO	Ptov1 (Mus musculus)	6480464	bisphenol S results in decreased methylation of PTOV1 exon and bisphenol S results in decreased methylation of PTOV1 promoter	CTD	PMID:33297965
Ptov1	Rat	4,4'-sulfonyldiphenol	multiple interactions	EXP		6480464	[bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in decreased expression of PTOV1 mRNA	CTD	PMID:36041667
Ptov1	Rat	4,4'-sulfonyldiphenol	affects methylation	ISO	Ptov1 (Mus musculus)	6480464	bisphenol S affects the methylation of PTOV1 gene	CTD	PMID:31683443
Ptov1	Rat	4,4'-sulfonyldiphenol	decreases methylation	ISO	PTOV1 (Homo sapiens)	6480464	bisphenol S results in decreased methylation of PTOV1 gene	CTD	PMID:31601247
Ptov1	Rat	aflatoxin B1	decreases expression	ISO	PTOV1 (Homo sapiens)	6480464	Aflatoxin B1 results in decreased expression of PTOV1 mRNA	CTD	PMID:27153756
Ptov1	Rat	all-trans-retinoic acid	increases expression	ISO	PTOV1 (Homo sapiens)	6480464	Tretinoin results in increased expression of PTOV1 mRNA	CTD	PMID:23724009
Ptov1	Rat	antirheumatic drug	increases expression	ISO	PTOV1 (Homo sapiens)	6480464	Antirheumatic Agents results in increased expression of PTOV1 mRNA	CTD	PMID:24449571
Ptov1	Rat	arsenite(3-)	increases methylation	ISO	PTOV1 (Homo sapiens)	6480464	arsenite results in increased methylation of PTOV1 promoter	CTD	PMID:23974009
Ptov1	Rat	benzo[a]pyrene	decreases methylation	ISO	PTOV1 (Homo sapiens)	6480464	Benzo(a)pyrene results in decreased methylation of PTOV1 3' UTR	CTD	PMID:27901495
Ptov1	Rat	beta-lapachone	decreases expression	ISO	PTOV1 (Homo sapiens)	6480464	beta-lapachone results in decreased expression of PTOV1 mRNA	CTD	PMID:38218311
Ptov1	Rat	bis(2-ethylhexyl) phthalate	increases expression	ISO	Ptov1 (Mus musculus)	6480464	Diethylhexyl Phthalate results in increased expression of PTOV1 mRNA	CTD	PMID:33754040
Ptov1	Rat	bisphenol A	affects expression	EXP		6480464	bisphenol A affects the expression of PTOV1 mRNA	CTD	PMID:25181051
Ptov1	Rat	bisphenol A	multiple interactions	EXP		6480464	[bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in decreased expression of PTOV1 mRNA	CTD	PMID:36041667
Ptov1	Rat	bisphenol A	increases expression	ISO	Ptov1 (Mus musculus)	6480464	bisphenol A results in increased expression of PTOV1 mRNA	CTD	PMID:33221593
Ptov1	Rat	bisphenol A	increases expression	EXP		6480464	bisphenol A results in increased expression of PTOV1 mRNA	CTD	PMID:34947998 and PMID:38750585
Ptov1	Rat	bisphenol F	multiple interactions	EXP		6480464	[bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in decreased expression of PTOV1 mRNA	CTD	PMID:36041667
Ptov1	Rat	caffeine	decreases phosphorylation	ISO	PTOV1 (Homo sapiens)	6480464	Caffeine results in decreased phosphorylation of PTOV1 protein	CTD	PMID:35688186
Ptov1	Rat	carbon nanotube	decreases expression	ISO	Ptov1 (Mus musculus)	6480464	Nanotubes and Carbon results in decreased expression of PTOV1 mRNA	CTD	PMID:25620056
Ptov1	Rat	chlorpyrifos	increases expression	ISO	Ptov1 (Mus musculus)	6480464	Chlorpyrifos results in increased expression of PTOV1 mRNA	CTD	PMID:37019170
Ptov1	Rat	clofibrate	decreases expression	ISO	Ptov1 (Mus musculus)	6480464	Clofibrate results in decreased expression of PTOV1 mRNA	CTD	PMID:17585979
Ptov1	Rat	clofibrate	multiple interactions	ISO	Ptov1 (Mus musculus)	6480464	[Clofibrate co-treated with Acetaminophen] affects the expression of PTOV1 mRNA and PPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of PTOV1 mRNA]	CTD	PMID:17585979
Ptov1	Rat	cocaine	affects expression	EXP		6480464	Cocaine affects the expression of PTOV1 mRNA	CTD	PMID:20187946
Ptov1	Rat	dioxygen	multiple interactions	ISO	Ptov1 (Mus musculus)	6480464	[sulforaphane affects the susceptibility to Oxygen] which affects the expression of PTOV1 mRNA	CTD	PMID:30529165
Ptov1	Rat	elemental selenium	increases expression	ISO	PTOV1 (Homo sapiens)	6480464	Selenium results in increased expression of PTOV1 mRNA	CTD	PMID:19244175
Ptov1	Rat	endosulfan	increases expression	EXP		6480464	Endosulfan results in increased expression of PTOV1 mRNA	CTD	PMID:29391264
Ptov1	Rat	folic acid	multiple interactions	ISO	Ptov1 (Mus musculus)	6480464	Folic Acid inhibits the reaction [1 and 2-Dimethylhydrazine results in increased expression of PTOV1 mRNA]	CTD	PMID:22206623
Ptov1	Rat	FR900359	increases phosphorylation	ISO	PTOV1 (Homo sapiens)	6480464	FR900359 results in increased phosphorylation of PTOV1 protein	CTD	PMID:37730182
Ptov1	Rat	genistein	decreases expression	ISO	PTOV1 (Homo sapiens)	6480464	Genistein results in decreased expression of PTOV1 mRNA	CTD	PMID:26865667
Ptov1	Rat	hypochlorous acid	decreases expression	ISO	Ptov1 (Mus musculus)	6480464	Hypochlorous Acid results in decreased expression of PTOV1 mRNA	CTD	PMID:19376150
Ptov1	Rat	mercury atom	decreases expression	ISO	Ptov1 (Mus musculus)	6480464	Mercury analog results in decreased expression of PTOV1 mRNA	CTD	PMID:25056781
Ptov1	Rat	mercury(0)	decreases expression	ISO	Ptov1 (Mus musculus)	6480464	Mercury analog results in decreased expression of PTOV1 mRNA	CTD	PMID:25056781
Ptov1	Rat	methotrexate	affects response to substance	ISO	PTOV1 (Homo sapiens)	6480464	PTOV1 protein affects the susceptibility to Methotrexate	CTD	PMID:16217747
Ptov1	Rat	paracetamol	multiple interactions	ISO	Ptov1 (Mus musculus)	6480464	[Clofibrate co-treated with Acetaminophen] affects the expression of PTOV1 mRNA and PPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of PTOV1 mRNA]	CTD	PMID:17585979
Ptov1	Rat	paracetamol	decreases expression	EXP		6480464	Acetaminophen results in decreased expression of PTOV1 mRNA	CTD	PMID:33387578
Ptov1	Rat	pirinixic acid	increases expression	EXP		6480464	pirinixic acid results in increased expression of PTOV1 mRNA	CTD	PMID:19162173
Ptov1	Rat	pyrogallol	increases expression	ISO	Ptov1 (Mus musculus)	6480464	Pyrogallol results in increased expression of PTOV1 mRNA	CTD	PMID:20362636
Ptov1	Rat	pyrogallol	multiple interactions	ISO	Ptov1 (Mus musculus)	6480464	Silymarin inhibits the reaction [Pyrogallol results in increased expression of PTOV1 mRNA]	CTD	PMID:20362636
Ptov1	Rat	resveratrol	multiple interactions	ISO	PTOV1 (Homo sapiens)	6480464	[Plant Extracts co-treated with Resveratrol] results in decreased expression of PTOV1 mRNA	CTD	PMID:23557933
Ptov1	Rat	Salinomycin	decreases expression	ISO	PTOV1 (Homo sapiens)	6480464	salinomycin results in decreased expression of PTOV1 mRNA	CTD	PMID:19682730
Ptov1	Rat	selenium atom	increases expression	ISO	PTOV1 (Homo sapiens)	6480464	Selenium results in increased expression of PTOV1 mRNA	CTD	PMID:19244175
Ptov1	Rat	sodium arsenite	increases expression	ISO	PTOV1 (Homo sapiens)	6480464	sodium arsenite results in increased expression of PTOV1 mRNA	CTD	PMID:38568856
Ptov1	Rat	sulforaphane	multiple interactions	ISO	Ptov1 (Mus musculus)	6480464	[sulforaphane affects the susceptibility to Oxygen] which affects the expression of PTOV1 mRNA	CTD	PMID:30529165
Ptov1	Rat	temozolomide	decreases expression	ISO	PTOV1 (Homo sapiens)	6480464	Temozolomide results in decreased expression of PTOV1 mRNA	CTD	PMID:31758290
Ptov1	Rat	thimerosal	decreases expression	ISO	PTOV1 (Homo sapiens)	6480464	Thimerosal results in decreased expression of PTOV1 mRNA	CTD	PMID:27188386
Ptov1	Rat	thioacetamide	decreases expression	EXP		6480464	Thioacetamide results in decreased expression of PTOV1 mRNA	CTD	PMID:34492290
Ptov1	Rat	thiram	decreases expression	ISO	PTOV1 (Homo sapiens)	6480464	Thiram results in decreased expression of PTOV1 mRNA	CTD	PMID:38568856
Ptov1	Rat	titanium dioxide	decreases methylation	ISO	Ptov1 (Mus musculus)	6480464	titanium dioxide results in decreased methylation of PTOV1 gene	CTD	PMID:35295148
Ptov1	Rat	toluene	increases expression	EXP		6480464	Toluene results in increased expression of PTOV1 mRNA	CTD	PMID:22967744
Ptov1	Rat	triphenyl phosphate	affects expression	ISO	PTOV1 (Homo sapiens)	6480464	triphenyl phosphate affects the expression of PTOV1 mRNA	CTD	PMID:37042841
Ptov1	Rat	triptonide	decreases expression	ISO	Ptov1 (Mus musculus)	6480464	triptonide results in decreased expression of PTOV1 mRNA	CTD	PMID:33045310
Ptov1	Rat	vinclozolin	decreases expression	EXP		6480464	vinclozolin results in decreased expression of PTOV1 mRNA	CTD	PMID:23034163
Ptov1	Rat	vorinostat	decreases expression	ISO	PTOV1 (Homo sapiens)	6480464	vorinostat results in decreased expression of PTOV1 mRNA	CTD	PMID:27188386

Biological Process

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Ptov1	Rat	positive regulation of transcription by RNA polymerase II	involved_in	IBA	MGI:1922863 more ...	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033

Cellular Component

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Ptov1	Rat	cytoplasm	located_in	IEA	UniProtKB-KW:KW-0963	1600115	GO_REF:0000043	UniProt	GO_REF:0000043
Ptov1	Rat	cytoplasm	located_in	IEA	UniProtKB-SubCell:SL-0086	1600115	GO_REF:0000044	UniProt	GO_REF:0000044
Ptov1	Rat	membrane	located_in	IEA	UniProtKB-KW:KW-0472	1600115	GO_REF:0000043	UniProt	GO_REF:0000043
Ptov1	Rat	nucleoplasm	located_in	IEA	UniProtKB:Q86YD1 and ensembl:ENSP00000375717	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Ptov1	Rat	nucleoplasm	located_in	ISO	PTOV1 (Homo sapiens) and UniProtKB:Q86YD1-1	1624291		RGD	GO_REF:0000052
Ptov1	Rat	nucleus	located_in	IEA	UniProtKB-SubCell:SL-0191	1600115	GO_REF:0000044	UniProt	GO_REF:0000044
Ptov1	Rat	nucleus	located_in	IEA	UniProtKB-KW:KW-0539	1600115	GO_REF:0000043	UniProt	GO_REF:0000043
Ptov1	Rat	perinuclear region of cytoplasm	located_in	IEA	UniProtKB-SubCell:SL-0198	1600115	GO_REF:0000044	UniProt	GO_REF:0000044
Ptov1	Rat	plasma membrane	located_in	IEA	UniProtKB-SubCell:SL-0039	1600115	GO_REF:0000044	UniProt	GO_REF:0000044
Ptov1	Rat	plasma membrane	located_in	IEA	UniProtKB-KW:KW-1003	1600115	GO_REF:0000043	UniProt	GO_REF:0000043
Ptov1	Rat	transcription regulator complex	part_of	IBA	MGI:1922863 more ...	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	GOA pipeline	RGD automated data pipeline
3.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

PMID:12477932

Ptov1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	104,483,553 - 104,496,161 (-)	NCBI		GRCr8
mRatBN7.2	1	95,347,065 - 95,354,514 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	95,347,068 - 95,353,613 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	1	100,732,451 - 100,738,997 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	109,205,116 - 109,211,662 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	102,495,525 - 102,502,071 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	100,859,346 - 100,866,917 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	100,859,349 - 100,865,894 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	1	101,923,967 - 101,931,540 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	1	95,335,898 - 95,342,444 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	1	95,414,009 - 95,420,555 (-)	NCBI
Celera	1	89,608,793 - 89,615,339 (-)	NCBI		Celera
Cytogenetic Map	1	q22	NCBI

PTOV1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	19	49,850,705 - 49,860,742 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	19	49,850,735 - 49,860,744 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	19	50,353,962 - 50,363,999 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	19	55,046,228 - 55,055,811 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	19	55,046,293 - 55,055,809	NCBI
Celera	19	47,223,866 - 47,233,449 (+)	NCBI		Celera
Cytogenetic Map	19	q13.33	NCBI
HuRef	19	46,730,759 - 46,740,340 (+)	NCBI		HuRef
CHM1_1	19	50,356,254 - 50,365,835 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	19	52,850,843 - 52,860,879 (+)	NCBI		T2T-CHM13v2.0

Ptov1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	7	44,512,491 - 44,523,542 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	7	44,512,491 - 44,519,212 (-)	Ensembl		GRCm39 Ensembl
GRCm38	7	44,863,067 - 44,870,519 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	7	44,863,067 - 44,869,788 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	7	52,118,438 - 52,125,158 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	7	44,731,110 - 44,737,830 (-)	NCBI		MGSCv36	mm8
Celera	7	40,313,277 - 40,320,004 (-)	NCBI		Celera
Cytogenetic Map	7	B3	NCBI
cM Map	7	28.94	NCBI

Ptov1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955559	1,069,481 - 1,078,735 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955559	1,070,856 - 1,079,052 (-)	NCBI	ChiLan1.0	ChiLan1.0

PTOV1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	20	55,960,378 - 55,977,107 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	19	57,884,596 - 57,897,748 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	19	46,863,575 - 46,874,494 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	19	55,779,380 - 55,789,585 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	19	55,779,915 - 55,789,585 (+)	Ensembl	panpan1.1		panPan2

PTOV1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	1	106,702,970 - 106,711,945 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	1	106,702,971 - 106,711,781 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	1	106,285,880 - 106,294,856 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	1	107,223,889 - 107,232,866 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	1	107,223,897 - 107,232,707 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	1	106,895,973 - 106,904,950 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	1	106,537,957 - 106,546,934 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	1	107,378,439 - 107,387,415 (-)	NCBI		UU_Cfam_GSD_1.0

Ptov1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024409349	22,021,538 - 22,031,225 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936664	3,639,675 - 3,648,919 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936664	3,639,681 - 3,649,415 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

PTOV1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	6	54,865,187 - 54,873,743 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	6	54,865,591 - 54,873,751 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	6	50,594,717 - 50,602,860 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

PTOV1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	6	43,009,167 - 43,018,347 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
Vero_WHO_p1.0	NW_023666073	22,983,767 - 22,993,630 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Ptov1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624832	4,468,426 - 4,476,721 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624832	4,468,427 - 4,476,805 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants in Ptov1
7 total Variants

Predicted Target Of

	Summary Value
Count of predictions:	89
Count of miRNA genes:	74
Interacting mature miRNAs:	78
Transcripts:	ENSRNOT00000027580
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
2313059	Bss55	Bone structure and strength QTL 55	3.2	0.0001	tibia size trait (VT:0100001)	tibia midshaft cross-sectional area (CMO:0001717)	1	43284731	118944897	Rat
70209	Niddm23	Non-insulin dependent diabetes mellitus QTL 23	2.82		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	1	94494440	198324465	Rat
631688	Hcas2	Hepatocarcinoma susceptibility QTL 2	3	0.0001	liver integrity trait (VT:0010547)	liver tumorous lesion number (CMO:0001068)	1	5925874	115540829	Rat
1582234	Gluco18	Glucose level QTL 18	3.4	0.0003	blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	1	78479925	123479925	Rat
1358359	Sradr1	Stress Responsive Adrenal Weight QTL 1	4.74		adrenal gland mass (VT:0010420)	both adrenal glands wet weight (CMO:0000164)	1	30882023	123479925	Rat
634314	Niddm44	Non-insulin dependent diabetes mellitus QTL 44			blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	1	49393289	199050459	Rat
1578780	Cm52	Cardiac mass QTL 52	3.3	0.0001	heart mass (VT:0007028)	heart wet weight (CMO:0000069)	1	81591954	219808434	Rat
1331793	Bp200	Blood pressure QTL 200	3.71601		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	94494440	172949803	Rat
1578654	Bss10	Bone structure and strength QTL 10	4		femur morphology trait (VT:0000559)	femoral neck cortical cross-sectional area (CMO:0001702)	1	49393172	159356837	Rat
2300324	Fetw1	Fetal weight QTL 1	12.1	0.005	fetal growth trait (VT:0004201)	fetal body weight (CMO:0002080)	1	85424647	100358001	Rat
1300121	Hrtrt1	Heart rate QTL 1	3.7		heart pumping trait (VT:2000009)	heart rate (CMO:0000002)	1	65789093	115540829	Rat
1331800	Scl25	Serum cholesterol level QTL 25	3.013		blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	1	94494440	117601394	Rat
7421628	Bp361	Blood pressure QTL 361		0.001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	1	66023617	118608521	Rat
631495	Bp96	Blood pressure QTL 96	4.52		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	22340647	102268831	Rat
70225	Bp58	Blood pressure QTL 58	3.3		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	32356093	162846471	Rat
2298545	Neuinf8	Neuroinflammation QTL 8	4.6		nervous system integrity trait (VT:0010566)	spinal cord beta-2 microglobulin mRNA level (CMO:0002125)	1	57336763	151090257	Rat
2313072	Bss53	Bone structure and strength QTL 53	4.3	0.0001	tibia length (VT:0004357)	tibia length (CMO:0000450)	1	43284731	118944897	Rat
10059597	Bp377	Blood pressure QTL 377	3.42	0.025	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	32737458	199368955	Rat
2313078	Bss54	Bone structure and strength QTL 54	3.5	0.0001	tibia area (VT:1000281)	tibia midshaft cross-sectional area (CMO:0001717)	1	43284731	118944897	Rat
1302788	Scl19	Serum cholesterol QTL 19	4.6	0.001	blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	1	90532338	123479925	Rat
1549903	Bp267	Blood pressure QTL 267			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	77876254	106047988	Rat
2313083	Bmd74	Bone mineral density QTL 74	4	0.0001	tibia mineral mass (VT:1000283)	total volumetric bone mineral density (CMO:0001728)	1	82174743	118944897	Rat
2313402	Anxrr24	Anxiety related response QTL 24			aggression-related behavior trait (VT:0015014)	tameness/aggressiveness composite score (CMO:0002136)	1	48963584	144267916	Rat
4889494	Scort2	Serum corticosterone level QTL 2	4.2		blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	1	80592172	125592172	Rat
724567	Tcas6	Tongue tumor susceptibility QTL 6	6.85		tongue integrity trait (VT:0010553)	number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)	1	92948896	144267916	Rat
61342	Bp27	Blood pressure QTL 27	3.4	0.0006	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	56732668	98773277	Rat
61344	Bp29	Blood pressure QTL 29	7.5		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	78350581	123350581	Rat
724521	Uae1	Urinary albumin excretion QTL 1	3.8	0.0001	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	1	90508614	173018436	Rat
1358902	Bw47	Body weight QTL 47	1.67		body mass (VT:0001259)	body weight (CMO:0000012)	1	90508614	180359386	Rat
1358192	Ept13	Estrogen-induced pituitary tumorigenesis QTL 13	3.4		pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	1	77494165	122494165	Rat
2313094	Bss58	Bone structure and strength QTL 58	3.7	0.0001	tibia strength trait (VT:1000284)	tibia total energy absorbed before break (CMO:0001736)	1	43284731	118944897	Rat
2300164	Bmd44	Bone mineral density QTL 44	5.4	0.0001	lumbar vertebra mineral mass (VT:0010511)	volumetric bone mineral density (CMO:0001553)	1	56949932	101949932	Rat
2313099	Bss56	Bone structure and strength QTL 56	2.4	0.0001	tibia size trait (VT:0100001)	tibia midshaft endosteal cross-sectional area (CMO:0001716)	1	43284731	118944897	Rat
2313098	Bmd70	Bone mineral density QTL 70	3.6	0.0001	tibia mineral mass (VT:1000283)	compact volumetric bone mineral density (CMO:0001730)	1	43284731	118944897	Rat
1300153	Bp171	Blood pressure QTL 171	3.37		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	1	90664883	143200202	Rat
731168	Bp154	Blood pressure QTL 154	3.4		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	94642644	214537671	Rat
738022	Anxrr13	Anxiety related response QTL 13	4.6	0.00039	locomotor behavior trait (VT:0001392)	number of 20 x 20 cm floor squares crossed into, out of or within a discrete space in an experimental apparatus (CMO:0001514)	1	83547917	128547917	Rat
152025249	Scl82	Serum cholesterol level QTL 82	4.77		blood cholesterol amount (VT:0000180)		1	50343510	99980958	Rat
10054135	Gmadr2	Adrenal mass QTL 2	1.97	0.0129	adrenal gland mass (VT:0010420)	both adrenal glands wet weight (CMO:0000164)	1	77857876	122857876	Rat
7411712	Strs4	Sensitivity to stroke QTL 4	8.7		cerebrum integrity trait (VT:0010549)	percentage of study population developing cerebrovascular lesions during a period of time (CMO:0000932)	1	78430536	123430536	Rat
1331749	Hrtrt11	Heart rate QTL 11	2.973		heart pumping trait (VT:2000009)	heart rate (CMO:0000002)	1	94494440	198211706	Rat
1331751	Bp199	Blood pressure QTL 199	3.60022		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	1	94494440	181830018	Rat
2293142	Bp314	Blood pressure QTL 314			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	92184926	137184926	Rat
2313051	Bss57	Bone structure and strength QTL 57	3.7	0.0001	tibia strength trait (VT:1000284)	bone polar moment of inertia (CMO:0001558)	1	43284731	118944897	Rat
724529	Cm16	Cardiac mass QTL 16	2.7		heart mass (VT:0007028)	calculated heart weight (CMO:0000073)	1	87580395	150700247	Rat

AU041779

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	1	95,347,089 - 95,347,307 (+)	MAPPER	mRatBN7.2
Rnor_6.0	1	100,859,371 - 100,859,588	NCBI	Rnor6.0
Rnor_5.0	1	101,923,992 - 101,924,209	UniSTS	Rnor5.0
RGSC_v3.4	1	95,335,921 - 95,336,138	UniSTS	RGSC3.4
Celera	1	89,608,816 - 89,609,033	UniSTS
Cytogenetic Map	1	q22	UniSTS

RH128246

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	1	95,347,246 - 95,347,442 (+)	MAPPER	mRatBN7.2
Rnor_6.0	1	100,859,528 - 100,859,723	NCBI	Rnor6.0
Rnor_5.0	1	101,924,149 - 101,924,344	UniSTS	Rnor5.0
RGSC_v3.4	1	95,336,078 - 95,336,273	UniSTS	RGSC3.4
Celera	1	89,608,973 - 89,609,168	UniSTS
RH 3.4 Map	1	905.09	UniSTS
Cytogenetic Map	1	q22	UniSTS

BI290136

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	1	95,346,681 - 95,346,872 (+)	MAPPER	mRatBN7.2
Rnor_6.0	1	100,858,963 - 100,859,153	NCBI	Rnor6.0
Rnor_5.0	1	101,923,584 - 101,923,774	UniSTS	Rnor5.0
RGSC_v3.4	1	95,335,513 - 95,335,703	UniSTS	RGSC3.4
Celera	1	89,608,408 - 89,608,598	UniSTS
RH 3.4 Map	1	909.6	UniSTS
Cytogenetic Map	1	q22	UniSTS

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	renal system	reproductive system	respiratory system
9	11	49	113	91	90	59	25	59	6	218	97	93	45	60	31


RefSeq Transcripts	NM_001008304	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_350313	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC094894	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC085836	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473979	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000001	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000027580 ⟹ ENSRNOP00000027580

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	1	95,347,068 - 95,353,613 (-)	Ensembl
Rnor_6.0 Ensembl	1	100,859,349 - 100,865,894 (-)	Ensembl

RefSeq Acc Id:

NM_001008304 ⟹ NP_001008305

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	104,483,555 - 104,490,101 (-)	NCBI
mRatBN7.2	1	95,347,067 - 95,353,613 (-)	NCBI
Rnor_6.0	1	100,859,348 - 100,865,894 (-)	NCBI
Rnor_5.0	1	101,923,967 - 101,931,540 (-)	NCBI
RGSC_v3.4	1	95,335,898 - 95,342,444 (-)	RGD
Celera	1	89,608,793 - 89,615,339 (-)	RGD

Sequence:

show sequence

CGCGTCCCCCGCCGCGGTCCCGCTCCGCTTCTCCCCGAAGCCGCGCGCCCGCGCCTGTCGGTCGGCGGACCCGCAGCTCCCCGTGAGGCCCACGGCCTCCTGCTCGCCATGGTCCGCCCGCGCCGTGC
CCCGCACCGCTCCGGCGCCGGGGGCCCCCTCGGAGGTCGTGGCCGGCCACCGCGGCCCCTGGTCGTCCGCGCCGTGCGCTCACGCTCCTGGCCTGCTGGCCCTCGAGGCCCGCAGCCGCCGCGGATCC
GGGCCCGTTCGGCCCCTCCCATGGAAGGTGCTCGAGTCTTTGGGGCCCTGGGGCCGATCGGGCCCTCCTCTCCTGGGCTGACTCTTGGGGGACTCGCAGTGAATGAGCACCGGCTCAGCAACAAACTG
CTGGCCTGGAGTGGCGTGCTGGAGTGGCAGGAGAAGCGTAGACCCTTCTCGGACTCCGCCGCAAAGCTGAAGCGCACCCTGCCCTGCCAGGCCTATGTGAACCAGGGCGAGAACCTGGAGACGGACCA
GTGGCCCCAGAAGCTGATCATGCAGCTCATCCCACAACAGCTGCTGACCACACTGGGCCCCCTGTTCCGAAACTCTCAGCTGGCCCAGTTCCACTTCACCAACAGAGACTGTGACTCCCTCAAGGGCC
TCTGCCGCATCATGGGCAATGGCTTCGCGGGCTGCATGCTCTTCCCCCACATTTCTCCTTGCGAGGTGCGTGTGCTCATGCTCCTGTACTCGTCTAAGAAGAAGATCTTCATGGGCCTCATCCCCTAC
GACCAGAGTGGCTTCGTCAATGCCATACGGCAGGTCATCACCACCCGCAAGCAGGCTGTGGGCCCTGGAGGGGTGCACTCTGGACCTGTTCAGATTGTCAACAACAAATTCTTGGCATGGAGTGGAGT
CATGGAGTGGCAAGAGCCCAGGCCTGAGCCCAACAGCCGGTCCAAGCGGTGGCTGCCATCCCACGTCTATGTGAACCAAGGAGAGATCCTGAGAACGGATCAGTGGCCTCGGAGGCTCTTCATGCAGC
TCATTCCACAGCAGTTGCTGACCACCCTCGTGCCACTGTTCCGGAACTCACGCCTGGTACAGTTCCACTTCACTAAGGACATGGAGACTCTGAAGAGCCTGTGCCGGATCATGGACAATGGCTTCGCG
GGCTGCGTGCACTTCTCCTATAAGGCCTCGTGCGAGGTTCGCGTGCTCATGCTCCTGTACTCCTCGGAGAAGAAGATCTTCATTGGCCTCATCCCGCATGACCAGAGCAACTTTGTCAATGGTATCCG
TCGTGTCATTGCCAACCAGCAGCAGGTCCTGCAGCGAAGCCTGGAGCAGGAGCAGCAGCAGCGAGGGATGGGTGGCTAGTGGACTCCTAGGCTGGGCAGGTCACAGTCCCAGACGAGGCCCCAGTGGA
GACTGGTGAGCGGCACTTGTGTTTGTGGGAAGCAGCAGGGTGACCCTGGCCTTAGACCTGCTGCATGAGTCACTGCCTCCTGTTACCAATATCCCTGGCAAGGAATGGGTGCCAGGGCCACAGCTTAA
GTACTGGGGGGGCAGGGGGCAGTTTCACTAGTAGAAGCCACCCCTCCTACTGCCTCCCAGGTCAGATGCTTCTGAGCAGGGGCTCCTGGGGACTGTACCTGCCCAGCAACCTGGAGGACAGCGTCCTG
AGGTCTCCCAAGGATGGTCCTTGCCCCTGTATGTTTCCCTAATAAAGCCTTTTAACCCAAAAAAAAAAAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XR_350313

Type:

NON-CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	104,483,553 - 104,496,161 (-)	NCBI
mRatBN7.2	1	95,347,065 - 95,354,514 (-)	NCBI
Rnor_6.0	1	100,859,346 - 100,866,917 (-)	NCBI
Rnor_5.0	1	101,923,967 - 101,931,540 (-)	NCBI

Sequence:

show sequence

ATCAATTATAAAACATGAGGTTTTAAAAAGCCAGCCTACAGCTCAGGACATTGCTCCAGTTGACTGGCATCATAGCTTGTGGTGTGCTGACAGGGGCCTGATATAATTTGGTCAAAGTAGTGTATGAA
TCAGCCAGGAAGATGTTTACTAGTTTAAAAGGCGGCGGGAGAGAACTTCTAGCATGCAAGAGGCTATAAATTCAAACCTCAGTACCCTATATATAGCTCGAGAGCCAAGTGTGGTAGTGCACACGCTA
ATAAAGGTGAAGACAGGAGGGTAGGAGTTCGAGGTCGACCTGGGTACATAAGCTAGGTTTTGAGTAGACACAACGCCACTAACACTGAGCTCAGGTAATCTAAGGCTGAATAACAGCACAGGTAAGAA
ACAAACTGAAGCAAGAAATACCACTGTACAGCCCTTTCAGATCAAGAACGTGATCTGGAAGAAGCAATTGCTGGAAGGCACAAGGGACAGTGGGCAGAGCCTGGACAAATAGGCTCGCAGCTACGCCT
GGCCTCTAGGTCACGCCCAGGCAGCGAGCGGCCCGCTGGAAGTTGTAGTCTTTTAGCTACCTTGCCACGTCACCGCCTCCAAGACGCAAGAACTCCTGGGTTCCTACATCTACCCCTCAGTCTGGTGG
TAGGTTCCGTCGCACCACCCATTATCCTGTCTACCGCCTTCTGTCCCTCCAGCGGTGAGGACTTGGTATTGTCTCACCAGCCCGAACTCTGAAAAACAGTTTCTTGTCATTTCCAACTCTAAAATCCT
CCCTCTCCGACCTTCTTGGTTCGCTCCAGCCACACCCCCTACAGTCCTCGATCCCGGTTTGTCAGCGCTGGCTCCCCAGCTCCATAGTCTGTTGGTTAGCGCCGGCTCCTCCTCTCCCCGGCGTTGGT
CCCGGCTCTCCCTCTTCTTCCACGTTGGTAGGCGCCAGCCCCCCCCGCATCCCCCCCTGCTTCGCGTTGGTTGGCGCCGGGCTCCCCTGTTCCCTGCAGTGGTTCGGCCGCGGCGACCCCTCAGCGGC
GCGTCCCCCGCCGCGGTCCCGCTCCGCTTCTCCCCGAAGCCGCGCGCCCGCGCCTGTCGGTCGGCGGACCCGCAGCTCCCCGTGAGGCCCACGGCCTCCTGCTCGCCATGGTCCGCCCGCGCCGTGCC
CCGCACCGCTCCGGCGCCGGGGGCCCCCTCGGAGGTCGTGGCCGGCCACCGCGGCCCCTGGTCGTCCGCGCCGTGCGCTCACGCTCCTGGCCTGCTGGCCCTCGAGGCCCGCAGCCGCCGCGGATCCG
GGCCCGTTCGGCCCCTCCCATGGAAGGTGCTCGAGTCTTTGGGGCCCTGGGGCCGATCGGGCCCTCCTCTCCTGGGCTGACTCTTGGGGGACTCGCAGTGAATGAGCACCGGCTCAGCAACAAACTGC
TGGCCTGGAGTGGCGTGCTGGAGTGGCAGGAGAAGCGTAGACCCTTCTCGGACTCCGCCGCAAAGCTGAAGCGCACCCTGCCCTGCCAGGCCTATGTGAACCAGGGCGAGAACCTGGAGACGGACCAG
TGGCCCCAGAAGCTGATCATGCAGCTCATCCCACAACAGCTGCTGACCACACTGGGCCCCCTGTTCCGAAACTCTCAGCTGGCCCAGTTCCACTTCACCAACAGAGACTGTGACTCCCTCAAGGGCCT
CTGCCGCATCATGGGCAATGGCTTCGCGGGCTGCATGCTCTTCCCCCACATTTCTCCTTGCGAGGTGCGTGTGCTCATGCTCCTGTACTCGTCTAAGAAGAAGATCTTCATGGGCCTCATCCCCTACG
ACCAGAGTGGCTTCGTCAATGCCATACGGCAGGTCATCACCACCCGCAAGCAGGCTGTGGGCCCTGGAGGGGTGCACTCTGGACCTGTTCAGATTGTCAACAACAAATTCTTGGCATGGAGTGGAGTC
ATGGAGTGGCAAGAGCCCAGGCCTGAGCCCAACAGCCGGTCCAAGCGGTGGCTGCCATCCCACGTCTATGTGAACCAAGGAGAGATCCTGAGAACGGATCAGTGGCCTCGGAGGCTCTTCATGCAGCT
CATTCCACAGCAGTTGCTGACCACCCTCGTGCCACTGTTCCGGAACTCACGCCTGGTACAGTTCCACTTCACTAAGGACATGGAGACTCTGAAGAGCCTGTGCCGGATCATGGACAATGGCTTCGCGG
GCTGCGTGCACTTCTCCTATAAGGCCTCGTGCGAGGTTCGCGTGCTCATGCTCCTGTACTCCTCGGAGAAGAAGATCTTCATTGGCCTCATCCCGCATGACCAGAGCAACTTTGTCAATGGTATCCGT
CGTGTCATTGCCAACCAGCAGCAGGTCCTGCAGCGAAGCCTGGAGCAGGAGCAGCAGCAGCGAGGGATGGGTGGCTAGTGGACTCCTAGGCTGGGCAGGTCACAGTCCCAGACGAGGCCCCAGTGGAG
ACTGGTCAGATGCTTCTGAGCAGGGGCTCCTGGGGACTGTACCTGCCCAGCAACCTGGAGGACAGCGTCCTGAGGTCTCCCAAGGATGGTCCTTGCCCCTGTATGTTTCCCTAATAAAGCCTTTTAAC
CCACA

hide sequence


Protein RefSeqs	NP_001008305	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH85836	(Get FASTA)	NCBI Sequence Viewer
	EDM07445	(Get FASTA)	NCBI Sequence Viewer
	EDM07446	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000027580
	ENSRNOP00000027580.3
GenBank Protein	Q5U2W6	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_001008305 ⟸ NM_001008304

- UniProtKB:

Q5U2W6 (UniProtKB/Swiss-Prot), A6JAT8 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MVRPRRAPHRSGAGGPLGGRGRPPRPLVVRAVRSRSWPAGPRGPQPPRIRARSAPPMEGARVFGALGPIGPSSPGLTLGGLAVNEHRLSNKLLAWSGVLEWQEKRRPFSDSAAKLKRTLPCQAYVNQG
ENLETDQWPQKLIMQLIPQQLLTTLGPLFRNSQLAQFHFTNRDCDSLKGLCRIMGNGFAGCMLFPHISPCEVRVLMLLYSSKKKIFMGLIPYDQSGFVNAIRQVITTRKQAVGPGGVHSGPVQIVNNK
FLAWSGVMEWQEPRPEPNSRSKRWLPSHVYVNQGEILRTDQWPRRLFMQLIPQQLLTTLVPLFRNSRLVQFHFTKDMETLKSLCRIMDNGFAGCVHFSYKASCEVRVLMLLYSSEKKIFIGLIPHDQS
NFVNGIRRVIANQQQVLQRSLEQEQQQRGMGG

hide sequence

Ensembl Acc Id:

ENSRNOP00000027580 ⟸ ENSRNOT00000027580

Protein Domains

Mediator complex subunit Med25 PTOV

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q5U2W6-F1-model_v2	AlphaFold	Q5U2W6	1-416	view protein structure

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

RGD ID:

13690011

Promoter ID:

EPDNEW_R536

Type:

initiation region

Name:

Ptov1_1

Description:

prostate tumor overexpressed 1

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	1	100,865,924 - 100,865,984	EPDNEW

Database	Acc Id	Source(s)
BioCyc Gene	G2FUF-59746	BioCyc
Ensembl Genes	ENSRNOG00000020358	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript	ENSRNOT00000027580	ENTREZGENE
	ENSRNOT00000027580.5	UniProtKB/Swiss-Prot
Gene3D-CATH	2.40.290.30	UniProtKB/Swiss-Prot
IMAGE_CLONE	IMAGE:7135127	IMAGE-MGC_LOAD
InterPro	Med25_PTOV	UniProtKB/Swiss-Prot
	PTOV_dom_sf	UniProtKB/Swiss-Prot
KEGG Report	rno:292888	UniProtKB/Swiss-Prot
MGC_CLONE	MGC:94482	IMAGE-MGC_LOAD
NCBI Gene	292888	ENTREZGENE
PANTHER	MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 25	UniProtKB/Swiss-Prot
	PTHR12433	UniProtKB/Swiss-Prot
Pfam	Med25	UniProtKB/Swiss-Prot
PhenoGen	Ptov1	PhenoGen
RatGTEx	ENSRNOG00000020358	RatGTEx
UniProt	A6JAT8	ENTREZGENE, UniProtKB/TrEMBL
	A6JAT9_RAT	UniProtKB/TrEMBL
	PTVO1_RAT	UniProtKB/Swiss-Prot, ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2018-12-04	Ptov1	PTOV1, extended AT-hook containing adaptor protein	Ptov1	prostate tumor overexpressed 1	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-11-06	Ptov1	prostate tumor overexpressed 1	Ptov1	prostate tumor over expressed gene 1	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2005-12-06	Ptov1	prostate tumor over expressed gene 1	Ptov1_predicted	prostate tumor over expressed gene 1 (predicted)	Symbol and Name updated	1559027	APPROVED
2005-01-12	Ptov1_predicted	prostate tumor over expressed gene 1 (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailable


InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailable


Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
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MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD