Myh14 (myosin heavy chain 14) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: Myh14 (myosin heavy chain 14) Rattus norvegicus
Analyze
Symbol: Myh14
Name: myosin heavy chain 14
RGD ID: 1306821
Description: Predicted to enable several functions, including ATP binding activity; actin filament binding activity; and microfilament motor activity. Predicted to be involved in several processes, including neuronal action potential; sensory perception of sound; and vocalization behavior. Predicted to act upstream of or within actin filament-based movement. Predicted to be located in several cellular components, including brush border; myosin II filament; and stress fiber. Predicted to be part of myosin II complex. Predicted to be active in cytoplasm and myosin filament. Human ortholog(s) of this gene implicated in autosomal dominant nonsyndromic deafness 4A and sensorineural hearing loss. Orthologous to human MYH14 (myosin heavy chain 14); PARTICIPATES IN myocarditis pathway; INTERACTS WITH 17beta-estradiol; 2,2',5,5'-tetrachlorobiphenyl; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: LOC308572; myosin, heavy chain 14; myosin, heavy chain 14, non-muscle; myosin, heavy polypeptide 14; myosin-14
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81104,232,778 - 104,295,369 (-)NCBIGRCr8
mRatBN7.2195,096,266 - 95,158,861 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl195,096,266 - 95,158,836 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1100,481,656 - 100,544,224 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01108,954,312 - 109,016,882 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01102,244,723 - 102,307,289 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01100,608,975 - 100,671,086 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1100,608,966 - 100,671,074 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01101,674,230 - 101,737,060 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4195,081,948 - 95,146,449 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1195,160,058 - 95,224,566 (-)NCBI
Celera189,358,486 - 89,415,924 (-)NCBICelera
Cytogenetic Map1q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model



  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Myh14Ratsensorineural hearing loss  ISOMYH14 (Homo sapiens)1600531DFNA4 more ...RGD 
1 to 11 of 11 rows
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Myh14RatAutosomal Dominant Deafness 4  ISOMYH14 (Homo sapiens)8554872ClinVar Annotator: match by term: Deafness and autosomal dominant 4ClinVarPMID:15015131 more ...
Myh14Ratautosomal dominant nonsyndromic deafness 4A  ISOMYH14 (Homo sapiens)8554872ClinVar more ...ClinVarPMID:15015131 more ...
Myh14RatCharcot-Marie-Tooth disease  ISOMYH14 (Homo sapiens)8554872ClinVar Annotator: match by term: Charcot-Marie-Tooth diseaseClinVarPMID:25741868
Myh14RatColorectal Cancer 10  ISOMYH14 (Homo sapiens)8554872ClinVar Annotator: match by term: Colorectal cancer more ...ClinVarPMID:28492532
Myh14Ratgenetic disease  ISOMYH14 (Homo sapiens)8554872ClinVar Annotator: match by term: Inborn genetic diseasesClinVarPMID:24033266 more ...
Myh14RatHearing Loss  ISOMYH14 (Homo sapiens)8554872ClinVar more ...ClinVarPMID:24033266 more ...
Myh14RatHearing Loss  ISOMYH14 (Homo sapiens)8554872ClinVar Annotator: match by term: Hearing impairmentClinVarPMID:24033266 more ...
Myh14RatMeniere's disease  ISOMYH14 (Homo sapiens)8554872ClinVar Annotator: match by term: Meniere diseaseClinVarPMID:24033266 more ...
Myh14RatNonsyndromic Sensorineural Hearing Loss  ISOMYH14 (Homo sapiens)8554872ClinVar Annotator: match by term: Nonsyndromic Hearing Loss and DominantClinVarPMID:28492532
Myh14RatPeripheral Neuropathy, Myopathy, Hoarseness, and Hearing Loss  ISOMYH14 (Homo sapiens)8554872ClinVar Annotator: match by term: Peripheral neuropathy more ...ClinVarPMID:15015131 more ...
Myh14Ratsensorineural hearing loss  ISOMYH14 (Homo sapiens)8554872ClinVar Annotator: match by term: Sensorineural hearing loss disorderClinVarPMID:25741868
1 to 11 of 11 rows
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Myh14RatProstatic Neoplasms  ISOMYH14 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:17013881

1 to 20 of 109 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Myh14Rat(1->4)-beta-D-glucan multiple interactionsISOMyh14 (Mus musculus)6480464[perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of MYH14 mRNACTDPMID:36331819
Myh14Rat17beta-estradiol increases expressionISOMyh14 (Mus musculus)6480464Estradiol results in increased expression of MYH14 mRNACTDPMID:15289156 and PMID:19484750
Myh14Rat17beta-estradiol decreases expressionEXP 6480464Estradiol results in decreased expression of MYH14 mRNACTDPMID:32145629
Myh14Rat17beta-estradiol multiple interactionsISOMYH14 (Homo sapiens)6480464[Estradiol co-treated with TGFB1 protein] results in decreased expression of MYH14 mRNACTDPMID:30165855
Myh14Rat2,2',5,5'-tetrachlorobiphenyl increases expressionEXP 64804642 more ...CTDPMID:23829299
Myh14Rat2,3,7,8-tetrachlorodibenzodioxine decreases expressionISOMyh14 (Mus musculus)6480464Tetrachlorodibenzodioxin results in decreased expression of MYH14 mRNA and Tetrachlorodibenzodioxin results in decreased expression of MYH14 proteinCTDPMID:21354282 and PMID:27105554
Myh14Rat2,3,7,8-tetrachlorodibenzodioxine decreases expressionEXP 6480464Tetrachlorodibenzodioxin results in decreased expression of MYH14 mRNACTDPMID:21215274
Myh14Rat2,4-dibromophenyl 2,4,5-tribromophenyl ether affects expressionISOMyh14 (Mus musculus)64804642 more ...CTDPMID:38648751
Myh14Rat2,6-dimethyl-4-tridecylmorpholine decreases expressionISOMyh14 (Mus musculus)6480464tridemorph results in decreased expression of MYH14 proteinCTDPMID:34737147
Myh14Rat2-bromohexadecanoic acid multiple interactionsISOMYH14 (Homo sapiens)64804642-bromopalmitate inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased palmitoylation of MYH14 protein]CTDPMID:38195004
Myh14Rat4,4'-sulfonyldiphenol increases expressionISOMyh14 (Mus musculus)6480464bisphenol S results in increased expression of MYH14 mRNACTDPMID:30951980
Myh14Rat4,4'-sulfonyldiphenol affects methylationISOMyh14 (Mus musculus)6480464bisphenol S affects the methylation of MYH14 geneCTDPMID:31683443
Myh14Rat4,4'-sulfonyldiphenol increases expressionISOMYH14 (Homo sapiens)6480464bisphenol S results in increased expression of MYH14 proteinCTDPMID:34186270
Myh14Rat4,4'-sulfonyldiphenol increases methylationISOMYH14 (Homo sapiens)6480464bisphenol S results in increased methylation of MYH14 geneCTDPMID:31601247
Myh14Rat4,4'-sulfonyldiphenol decreases methylationISOMyh14 (Mus musculus)6480464bisphenol S results in decreased methylation of MYH14 exonCTDPMID:33297965
Myh14Rat4-[3-(4-tert-butylphenyl)-2-methylpropyl]-2,6-dimethylmorpholine decreases expressionISOMyh14 (Mus musculus)6480464fenpropimorph results in decreased expression of MYH14 proteinCTDPMID:34737147
Myh14Rat6-propyl-2-thiouracil decreases expressionEXP 6480464Propylthiouracil results in decreased expression of MYH14 mRNACTDPMID:24780913
Myh14Ratacetamide increases expressionEXP 6480464acetamide results in increased expression of MYH14 mRNACTDPMID:31881176
Myh14Rataflatoxin B1 affects expressionISOMYH14 (Homo sapiens)6480464Aflatoxin B1 affects the expression of MYH14 proteinCTDPMID:20106945
Myh14Rataflatoxin B1 increases expressionEXP 6480464Aflatoxin B1 results in increased expression of MYH14 mRNACTDPMID:23630614

1 to 20 of 109 rows

Biological Process
1 to 20 of 20 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Myh14Ratactin filament-based movement acts_upstream_of_or_withinISOMyh14 (Mus musculus)1624291 PMID:14594953 and PMID:15845534RGDPMID:14594953 and PMID:15845534
Myh14Ratactin filament-based movement acts_upstream_of_or_withinIEAUniProtKB:Q6URW6 and ensembl:ENSMUSP000001471151600115GO_REF:0000107EnsemblGO_REF:0000107
Myh14Ratactomyosin structure organization involved_inISOMYH14 (Homo sapiens)1624291 PMID:24072716RGDPMID:24072716
Myh14Ratactomyosin structure organization involved_inIEAUniProtKB:Q7Z406 and ensembl:ENSP000004935941600115GO_REF:0000107EnsemblGO_REF:0000107
Myh14Ratactomyosin structure organization involved_inIBAMGI:1930780 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Myh14Ratbiological_process  ND 15984073/2007: no relevant rat dataRGD 
Myh14Ratmitochondrion organization involved_inISOMYH14 (Homo sapiens)1624291 PMID:21480433RGDPMID:21480433
Myh14Ratmitochondrion organization involved_inIEAUniProtKB:Q7Z406 and ensembl:ENSP000004935941600115GO_REF:0000107EnsemblGO_REF:0000107
Myh14Ratmitotic cytokinesis involved_inIBAMGI:1930780 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Myh14Ratneuronal action potential involved_inISOMYH14 (Homo sapiens)1624291 PMID:21480433RGDPMID:21480433
Myh14Ratneuronal action potential involved_inIEAUniProtKB:Q7Z406 and ensembl:ENSP000004935941600115GO_REF:0000107EnsemblGO_REF:0000107
Myh14Ratregulation of cell shape involved_inIBAMGI:1930780 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Myh14Ratsensory perception of sound involved_inISOMYH14 (Homo sapiens)1624291 PMID:21480433RGDPMID:21480433
Myh14Ratsensory perception of sound involved_inIEAUniProtKB:Q7Z406 and ensembl:ENSP000004935941600115GO_REF:0000107EnsemblGO_REF:0000107
Myh14Ratskeletal muscle contraction involved_inISOMYH14 (Homo sapiens)1624291 PMID:21480433RGDPMID:21480433
Myh14Ratskeletal muscle contraction involved_inIEAUniProtKB:Q7Z406 and ensembl:ENSP000004935941600115GO_REF:0000107EnsemblGO_REF:0000107
Myh14Ratskeletal muscle tissue development involved_inISOMYH14 (Homo sapiens)1624291 PMID:21480433RGDPMID:21480433
Myh14Ratskeletal muscle tissue development involved_inIEAUniProtKB:Q7Z406 and ensembl:ENSP000004935941600115GO_REF:0000107EnsemblGO_REF:0000107
Myh14Ratvocalization behavior involved_inISOMYH14 (Homo sapiens)1624291 PMID:21480433RGDPMID:21480433
Myh14Ratvocalization behavior involved_inIEAUniProtKB:Q7Z406 and ensembl:ENSP000004935941600115GO_REF:0000107EnsemblGO_REF:0000107
1 to 20 of 20 rows

Cellular Component
1 to 20 of 25 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Myh14Ratactomyosin located_inISOMYH14 (Homo sapiens)1624291 PMID:24072716RGDPMID:24072716
Myh14Ratactomyosin located_inIEAUniProtKB:Q7Z406 and ensembl:ENSP000004935941600115GO_REF:0000107EnsemblGO_REF:0000107
Myh14Rataxon located_inISOMyh14 (Mus musculus)1624291 PMID:15880105RGDPMID:15880105
Myh14Rataxon located_inIEAUniProtKB:Q6URW6 and ensembl:ENSMUSP000001471151600115GO_REF:0000107EnsemblGO_REF:0000107
Myh14Ratbrush border located_inIEAUniProtKB:Q6URW6 and ensembl:ENSMUSP000001471151600115GO_REF:0000107EnsemblGO_REF:0000107
Myh14Ratbrush border located_inISOMyh14 (Mus musculus)1624291 PMID:22114352RGDPMID:22114352
Myh14Ratcytoplasm is_active_inIBACGD:CAL0000200546 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Myh14Ratcytoplasm located_inIEAUniProtKB:Q6URW6 and ensembl:ENSMUSP000001471151600115GO_REF:0000107EnsemblGO_REF:0000107
Myh14Ratcytoplasm located_inISOMyh14 (Mus musculus)1624291 PMID:15880105RGDPMID:15880105
Myh14Ratgrowth cone located_inISOMyh14 (Mus musculus)1624291 PMID:15880105RGDPMID:15880105
Myh14Ratgrowth cone located_inIEAUniProtKB:Q6URW6 and ensembl:ENSMUSP000001471151600115GO_REF:0000107EnsemblGO_REF:0000107
Myh14Ratintracellular membraneless organelle located_inIEAARBA:ARBA000290791600115GO_REF:0000117UniProtGO_REF:0000117
Myh14Ratmyosin complex part_ofIEAInterPro:IPR001609 more ...1600115GO_REF:0000002InterProGO_REF:0000002
Myh14Ratmyosin complex part_ofIEAInterPro:IPR001609 and InterPro:IPR0029281600115GO_REF:0000002InterProGO_REF:0000002
Myh14Ratmyosin complex part_ofISOMyh14 (Mus musculus)1624291 PMID:14594953RGDPMID:14594953
Myh14Ratmyosin complex part_ofIEAUniProtKB:Q6URW6 and ensembl:ENSMUSP000001471151600115GO_REF:0000107EnsemblGO_REF:0000107
Myh14Ratmyosin complex part_ofIEAUniProtKB-KW:KW-05181600115GO_REF:0000043UniProtGO_REF:0000043
Myh14Ratmyosin filament is_active_inIBAPANTHER:PTN005210253 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Myh14Ratmyosin II complex part_ofISOMYH14 (Homo sapiens)1624291 PMID:24072716RGDPMID:24072716
Myh14Ratmyosin II complex part_ofIEAUniProtKB:Q7Z406 and ensembl:ENSP000004935941600115GO_REF:0000107EnsemblGO_REF:0000107
1 to 20 of 25 rows

Molecular Function
1 to 20 of 23 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Myh14Ratactin binding enablesIEAUniProtKB-KW:KW-00091600115GO_REF:0000043UniProtGO_REF:0000043
Myh14Ratactin filament binding contributes_toISOMYH14 (Homo sapiens)1624291 PMID:24072716RGDPMID:24072716
Myh14Ratactin filament binding contributes_toIEAUniProtKB:Q7Z406 and ensembl:ENSP000004935941600115GO_REF:0000107EnsemblGO_REF:0000107
Myh14Ratactin filament binding enablesIEAUniProtKB:Q6URW6 and ensembl:ENSMUSP000001471151600115GO_REF:0000107EnsemblGO_REF:0000107
Myh14Ratactin filament binding enablesIEAInterPro:IPR0089891600115GO_REF:0000002InterProGO_REF:0000002
Myh14Ratactin filament binding enablesISOMyh14 (Mus musculus)1624291 PMID:14594953 and PMID:15845534RGDPMID:14594953 and PMID:15845534
Myh14Ratactin filament binding enablesIBAFB:FBgn0026059 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Myh14RatATP binding enablesIEAInterPro:IPR001609 more ...1600115GO_REF:0000002InterProGO_REF:0000002
Myh14RatATP binding enablesISOMyh14 (Mus musculus)1624291 PMID:15845534RGDPMID:15845534
Myh14RatATP binding enablesIEAInterPro:IPR0016091600115GO_REF:0000002InterProGO_REF:0000002
Myh14RatATP binding enablesIEAUniProtKB:Q6URW6 and ensembl:ENSMUSP000001471151600115GO_REF:0000107EnsemblGO_REF:0000107
Myh14RatATP binding enablesIEAUniRule:UR0006864691600115GO_REF:0000104UniProtGO_REF:0000104
Myh14RatATP binding enablesIEAUniProtKB-KW:KW-00671600115GO_REF:0000043UniProtGO_REF:0000043
Myh14Ratcytoskeletal motor activity enablesIEAUniRule:UR0006864691600115GO_REF:0000104UniProtGO_REF:0000104
Myh14Ratcytoskeletal motor activity enablesIEAInterPro:IPR001609 more ...1600115GO_REF:0000002InterProGO_REF:0000002
Myh14Ratcytoskeletal motor activity enablesIEAInterPro:IPR0016091600115GO_REF:0000002InterProGO_REF:0000002
Myh14Ratmicrofilament motor activity contributes_toISOMYH14 (Homo sapiens)1624291 PMID:24072716RGDPMID:24072716
Myh14Ratmicrofilament motor activity contributes_toIEAUniProtKB:Q7Z406 and ensembl:ENSP000004935941600115GO_REF:0000107EnsemblGO_REF:0000107
Myh14Ratmicrofilament motor activity enablesIEAUniProtKB:Q6URW6 and ensembl:ENSMUSP000001471151600115GO_REF:0000107EnsemblGO_REF:0000107
Myh14Ratmicrofilament motor activity enablesISOMyh14 (Mus musculus)1624291 PMID:14594953 and PMID:15845534RGDPMID:14594953 and PMID:15845534
1 to 20 of 23 rows

Imported Annotations - KEGG (archival)

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Myh14Ratmyocarditis pathway  IEA 6907045 KEGGrno:05416

1 to 9 of 9 rows
#
Reference Title
Reference Citation
1. Nonmuscle myosin heavy-chain gene MYH14 is expressed in cochlea and mutated in patients affected by autosomal dominant hearing impairment (DFNA4). Donaudy F, etal., Am J Hum Genet. 2004 Apr;74(4):770-6. Epub 2004 Mar 10.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
5. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
6. GOA pipeline RGD automated data pipeline
7. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
9. Comprehensive gene review and curation RGD comprehensive gene curation
1 to 9 of 9 rows
PMID:14594953   PMID:15774463   PMID:15845534   PMID:15880105   PMID:17634366   PMID:19056867   PMID:19946888   PMID:21480433   PMID:21700703   PMID:22114352   PMID:23376485   PMID:24072716  
PMID:24625528   PMID:35352799  



Myh14
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81104,232,778 - 104,295,369 (-)NCBIGRCr8
mRatBN7.2195,096,266 - 95,158,861 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl195,096,266 - 95,158,836 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1100,481,656 - 100,544,224 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01108,954,312 - 109,016,882 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01102,244,723 - 102,307,289 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01100,608,975 - 100,671,086 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1100,608,966 - 100,671,074 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01101,674,230 - 101,737,060 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4195,081,948 - 95,146,449 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1195,160,058 - 95,224,566 (-)NCBI
Celera189,358,486 - 89,415,924 (-)NCBICelera
Cytogenetic Map1q22NCBI
MYH14
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381950,203,622 - 50,310,540 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1950,188,186 - 50,310,542 (+)EnsemblGRCh38hg38GRCh38
GRCh371950,706,879 - 50,813,797 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361955,398,697 - 55,505,613 (+)NCBINCBI36Build 36hg18NCBI36
Build 341955,398,696 - 55,505,610NCBI
Celera1947,757,054 - 47,864,132 (+)NCBICelera
Cytogenetic Map19q13.33NCBI
HuRef1947,045,574 - 47,152,034 (+)NCBIHuRef
CHM1_11950,708,735 - 50,815,614 (+)NCBICHM1_1
T2T-CHM13v2.01953,291,137 - 53,398,069 (+)NCBIT2T-CHM13v2.0
Myh14
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39744,255,227 - 44,320,296 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl744,255,227 - 44,320,267 (-)EnsemblGRCm39 Ensembl
GRCm38744,605,803 - 44,670,872 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl744,605,803 - 44,670,843 (-)EnsemblGRCm38mm10GRCm38
MGSCv37751,861,189 - 51,920,873 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36744,473,861 - 44,533,545 (-)NCBIMGSCv36mm8
Celera740,055,770 - 40,115,661 (-)NCBICelera
Cytogenetic Map7B3NCBI
cM Map728.85NCBI
Myh14
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955559797,107 - 853,053 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955559796,455 - 856,082 (-)NCBIChiLan1.0ChiLan1.0
MYH14
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22056,271,738 - 56,375,910 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11958,192,707 - 58,297,218 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01947,169,303 - 47,273,815 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11956,076,709 - 56,178,650 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1956,081,644 - 56,177,902 (+)Ensemblpanpan1.1panPan2
MYH14
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11106,371,952 - 106,460,388 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1106,371,939 - 106,458,901 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1105,955,580 - 106,057,500 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01106,893,609 - 106,995,633 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1106,893,609 - 106,977,223 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11106,565,643 - 106,667,627 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01106,207,137 - 106,309,519 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01107,047,874 - 107,149,770 (-)NCBIUU_Cfam_GSD_1.0
Myh14
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934922,245,734 - 22,308,625 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936889122,853 - 183,928 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936889121,724 - 184,374 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MYH14
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl655,113,521 - 55,200,750 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1655,097,851 - 55,200,754 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2650,879,598 - 50,942,693 (+)NCBISscrofa10.2Sscrofa10.2susScr3
MYH14
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1643,270,363 - 43,372,927 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl643,275,715 - 43,372,190 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607323,249,905 - 23,356,116 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Myh14
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248324,176,914 - 4,230,863 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248324,176,632 - 4,234,763 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

.

.
Variants in Myh14
159 total Variants


Assembly: Rnor_5.0

Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Strain Variant Page
1 101693588 101693589 C A snv BBDP/WorN (KNAW) View more Information


Assembly: Rnor_6.0

Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Strain Variant Page
1 100628201 100628202 C A snv BBDP/Wor (RGD) View more Information

Predicted Target Of
Summary Value
Count of predictions:95
Count of miRNA genes:68
Interacting mature miRNAs:80
Transcripts:ENSRNOT00000027132
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 45 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
2313059Bss55Bone structure and strength QTL 553.20.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)143284731118944897Rat
70209Niddm23Non-insulin dependent diabetes mellitus QTL 232.82blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)194494440198324465Rat
631688Hcas2Hepatocarcinoma susceptibility QTL 230.0001liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)15925874115540829Rat
1582234Gluco18Glucose level QTL 183.40.0003blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)178479925123479925Rat
1358359Sradr1Stress Responsive Adrenal Weight QTL 14.74adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)130882023123479925Rat
634314Niddm44Non-insulin dependent diabetes mellitus QTL 44blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)149393289199050459Rat
1578780Cm52Cardiac mass QTL 523.30.0001heart mass (VT:0007028)heart wet weight (CMO:0000069)181591954219808434Rat
1331793Bp200Blood pressure QTL 2003.71601arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)194494440172949803Rat
1578654Bss10Bone structure and strength QTL 104femur morphology trait (VT:0000559)femoral neck cortical cross-sectional area (CMO:0001702)149393172159356837Rat
2300324Fetw1Fetal weight QTL 112.10.005fetal growth trait (VT:0004201)fetal body weight (CMO:0002080)185424647100358001Rat

1 to 10 of 45 rows
D1Got97  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr81104,270,009 - 104,270,199 (+)Marker Load Pipeline
mRatBN7.2195,133,500 - 95,133,690 (+)MAPPERmRatBN7.2
Rnor_6.01100,645,522 - 100,645,711NCBIRnor6.0
Rnor_5.01101,711,501 - 101,711,690UniSTSRnor5.0
RGSC_v3.4195,120,716 - 95,120,903RGDRGSC3.4
RGSC_v3.4195,120,717 - 95,120,906UniSTSRGSC3.4
RGSC_v3.1195,198,827 - 95,199,014RGD
Celera189,395,834 - 89,396,023UniSTS
RH 3.4 Map1903.6RGD
RH 3.4 Map1903.6UniSTS
RH 2.0 Map1589.7RGD
Cytogenetic Map1q22UniSTS
AU048673  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2195,099,704 - 95,099,802 (+)MAPPERmRatBN7.2
Rnor_6.01100,612,414 - 100,612,511NCBIRnor6.0
Rnor_5.01101,677,801 - 101,677,898UniSTSRnor5.0
RGSC_v3.4195,085,387 - 95,085,484UniSTSRGSC3.4
Celera189,361,925 - 89,362,022UniSTS
Cytogenetic Map1q22UniSTS
RH142730  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2195,096,265 - 95,096,365 (+)MAPPERmRatBN7.2
Rnor_6.01100,608,975 - 100,609,074NCBIRnor6.0
Rnor_5.01101,674,362 - 101,674,461UniSTSRnor5.0
RGSC_v3.4195,081,948 - 95,082,047UniSTSRGSC3.4
Celera189,358,486 - 89,358,585UniSTS
RH 3.4 Map1904.9UniSTS
Cytogenetic Map1q22UniSTS
AW532989  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2195,096,410 - 95,096,630 (+)MAPPERmRatBN7.2
Rnor_6.01100,609,120 - 100,609,339NCBIRnor6.0
Rnor_5.01101,674,507 - 101,674,726UniSTSRnor5.0
RGSC_v3.4195,082,093 - 95,082,312UniSTSRGSC3.4
Celera189,358,631 - 89,358,850UniSTS
RH 3.4 Map1903.9UniSTS
Cytogenetic Map1q22UniSTS




alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31



Ensembl Acc Id: ENSRNOT00000027132   ⟹   ENSRNOP00000027132
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl195,096,266 - 95,158,836 (-)Ensembl
Rnor_6.0 Ensembl1100,608,975 - 100,671,074 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000091760   ⟹   ENSRNOP00000072636
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl195,096,266 - 95,158,836 (-)Ensembl
Rnor_6.0 Ensembl1100,608,966 - 100,669,684 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000094017   ⟹   ENSRNOP00000089689
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl195,096,266 - 95,158,836 (-)Ensembl
RefSeq Acc Id: NM_001100690   ⟹   NP_001094160
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81104,232,778 - 104,295,344 (-)NCBI
mRatBN7.2195,096,266 - 95,158,836 (-)NCBI
Rnor_6.01100,608,975 - 100,671,074 (-)NCBI
Rnor_5.01101,674,230 - 101,737,060 (-)NCBI
RGSC_v3.4195,081,948 - 95,146,449 (-)RGD
Celera189,358,486 - 89,415,924 (-)RGD
Sequence:
RefSeq Acc Id: XM_006229056   ⟹   XP_006229118
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81104,232,778 - 104,295,369 (-)NCBI
mRatBN7.2195,096,665 - 95,158,861 (-)NCBI
Rnor_6.01100,608,975 - 100,671,086 (-)NCBI
Rnor_5.01101,674,230 - 101,737,060 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006229057   ⟹   XP_006229119
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81104,232,778 - 104,295,369 (-)NCBI
mRatBN7.2195,096,665 - 95,158,861 (-)NCBI
Rnor_6.01100,608,975 - 100,671,086 (-)NCBI
Rnor_5.01101,674,230 - 101,737,060 (-)NCBI
Sequence:
RefSeq Acc Id: XM_063261923   ⟹   XP_063117993
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81104,232,778 - 104,295,365 (-)NCBI
RefSeq Acc Id: NP_001094160   ⟸   NM_001100690
- UniProtKB: A0A0G2K3H1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006229119   ⟸   XM_006229057
- Peptide Label: isoform X2
- UniProtKB: A0A0G2K3H1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006229118   ⟸   XM_006229056
- Peptide Label: isoform X1
- UniProtKB: A0A0G2K3H1 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000072636   ⟸   ENSRNOT00000091760
Ensembl Acc Id: ENSRNOP00000027132   ⟸   ENSRNOT00000027132
Name Modeler Protein Id AA Range Protein Structure
AF-F1LNF0-F1-model_v2 AlphaFold F1LNF0 1-2000 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

RGD ID:13690004
Promoter ID:EPDNEW_R529
Type:initiation region
Name:Myh14_1
Description:myosin heavy chain 14
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01100,669,569 - 100,669,629EPDNEW


1 to 40 of 44 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-59757 BioCyc
Ensembl Genes ENSRNOG00000020014 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000027132.6 UniProtKB/TrEMBL
  ENSRNOT00000091760.2 UniProtKB/TrEMBL
  ENSRNOT00000094017 ENTREZGENE
  ENSRNOT00000094017.1 UniProtKB/TrEMBL
  ENSRNOT00000139210 ENTREZGENE
Gene3D-CATH 1.10.10.820 UniProtKB/TrEMBL
  1.20.5.340 UniProtKB/TrEMBL
  1.20.5.4820 UniProtKB/TrEMBL
  1.20.58.530 UniProtKB/TrEMBL
  2.30.30.360 UniProtKB/TrEMBL
  3.40.850.10 UniProtKB/TrEMBL
  6.10.250.2420 UniProtKB/TrEMBL
  Myosin VI head, motor domain, U50 subdomain UniProtKB/TrEMBL
InterPro IQ_motif_EF-hand-BS UniProtKB/TrEMBL
  Kinesin_motor_dom_sf UniProtKB/TrEMBL
  Myosin_head_motor_dom UniProtKB/TrEMBL
  Myosin_N UniProtKB/TrEMBL
  Myosin_S1_N UniProtKB/TrEMBL
  Myosin_tail UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/TrEMBL
NCBI Gene 308572 ENTREZGENE
PANTHER MYOSIN UniProtKB/TrEMBL
  MYOSIN HEAVY CHAIN, NON-MUSCLE UniProtKB/TrEMBL
  MYOSIN-11 UniProtKB/TrEMBL
  MYOSIN-14 UniProtKB/TrEMBL
Pfam Myosin_head UniProtKB/TrEMBL
  Myosin_N UniProtKB/TrEMBL
  Myosin_tail_1 UniProtKB/TrEMBL
PhenoGen Myh14 PhenoGen
PRINTS MYOSINHEAVY UniProtKB/TrEMBL
PROSITE MYOSIN_MOTOR UniProtKB/TrEMBL
  PS50096 UniProtKB/TrEMBL
  SH3_LIKE UniProtKB/TrEMBL
RatGTEx ENSRNOG00000020014 RatGTEx
SMART MYSc UniProtKB/TrEMBL
  SM00015 UniProtKB/TrEMBL
Superfamily-SCOP Myosin rod fragments UniProtKB/TrEMBL
  SSF52540 UniProtKB/TrEMBL
1 to 40 of 44 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-08-29 Myh14  myosin heavy chain 14  Myh14  myosin, heavy chain 14, non-muscle  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2011-08-02 Myh14  myosin, heavy chain 14, non-muscle  Myh14  myosin, heavy chain 14  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-10-23 Myh14  myosin, heavy chain 14  Myh14  myosin, heavy polypeptide 14  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-12-06 Myh14  myosin, heavy polypeptide 14  Myh14_predicted  myosin, heavy polypeptide 14 (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Myh14_predicted  myosin, heavy polypeptide 14 (predicted)      Symbol and Name status set to approved 70820 APPROVED