Farp1 (FERM, ARH/RhoGEF and pleckstrin domain protein 1) - Rat Genome Database

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Gene: Farp1 (FERM, ARH/RhoGEF and pleckstrin domain protein 1) Rattus norvegicus
Analyze
Symbol: Farp1
Name: FERM, ARH/RhoGEF and pleckstrin domain protein 1
RGD ID: 1305346
Description: Enables guanyl-nucleotide exchange factor activity and small GTPase binding activity. Involved in several processes, including dendrite morphogenesis; retrograde trans-synaptic signaling by trans-synaptic protein complex; and synapse organization. Located in cytoplasmic side of plasma membrane; cytosol; and dendrite. Is active in glutamatergic synapse. Is extrinsic component of postsynaptic membrane. Orthologous to human FARP1 (FERM, ARH/RhoGEF and pleckstrin domain protein 1); INTERACTS WITH 17beta-estradiol; 3-chloropropane-1,2-diol; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: FERM, ARHGEF and pleckstrin domain-containing protein 1; FERM, RhoGEF (Arhgef) and pleckstrin domain protein 1 (chondrocyte-derived); FERM, RhoGEF and pleckstrin domain-containing protein 1; FERMRhoGEF (Arhgef) and pleckstrin domain protein 1-like; LOC306183
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr815104,531,196 - 104,770,148 (+)NCBIGRCr8
mRatBN7.21598,124,304 - 98,363,299 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1598,182,329 - 98,363,299 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx15102,114,666 - 102,296,077 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.015103,216,836 - 103,397,759 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.015100,143,970 - 100,325,367 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.015106,375,298 - 106,625,837 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl15106,434,177 - 106,625,837 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.015109,772,475 - 110,020,013 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.415106,171,848 - 106,253,441 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.115106,132,880 - 106,268,432 (+)NCBI
Celera1596,990,113 - 97,147,686 (+)NCBICelera
Cytogenetic Map15q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Farp1RatAnal Atresia, Hypospadias, and Penoscrotal Inversion  ISOFARP1 (Homo sapiens)8554872ClinVar Annotator: match by term: Anal atresia more ...ClinVarPMID:31690835
Farp1Ratholoprosencephaly 5  ISOFARP1 (Homo sapiens)8554872ClinVar Annotator: match by term: Holoprosencephaly 5ClinVarPMID:17274816 more ...
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Farp1Ratbasal cell carcinoma  ISOFARP1 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:36428691
Farp1Ratsubstance-related disorder  ISOFARP1 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:20098672

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Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Farp1Rat(1->4)-beta-D-glucan multiple interactionsISOFarp1 (Mus musculus)6480464[perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of FARP1 mRNACTDPMID:36331819
Farp1Rat1,2-dimethylhydrazine multiple interactionsISOFarp1 (Mus musculus)6480464[1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of FARP1 mRNACTDPMID:22206623
Farp1Rat17beta-estradiol multiple interactionsISOFARP1 (Homo sapiens)6480464Estradiol inhibits the reaction [afimoxifene results in increased expression of FARP1 mRNA]CTDPMID:16849584
Farp1Rat17beta-estradiol increases expressionISOFarp1 (Mus musculus)6480464Estradiol results in increased expression of FARP1 mRNACTDPMID:39298647
Farp1Rat17beta-estradiol decreases expressionEXP 6480464Estradiol results in decreased expression of FARP1 mRNACTDPMID:20068009
Farp1Rat2,2',4,4'-Tetrabromodiphenyl ether affects expressionISOFarp1 (Mus musculus)64804642 more ...CTDPMID:30294300
Farp1Rat2,2',4,4'-Tetrabromodiphenyl ether multiple interactionsISOFarp1 (Mus musculus)6480464[Flame Retardants results in increased abundance of 2 more ...CTDPMID:38995820
Farp1Rat2,3,7,8-tetrachlorodibenzodioxine decreases expressionISOFarp1 (Mus musculus)6480464Tetrachlorodibenzodioxin results in decreased expression of FARP1 mRNACTDPMID:26290441
Farp1Rat3-chloropropane-1,2-diol increases expressionEXP 6480464alpha-Chlorohydrin results in increased expression of FARP1 proteinCTDPMID:34915118
Farp1Rat4,4'-diaminodiphenylmethane affects expressionISOFarp1 (Mus musculus)64804644 and 4'-diaminodiphenylmethane affects the expression of FARP1 mRNACTDPMID:18648102
Farp1Rat4,4'-sulfonyldiphenol increases expressionISOFarp1 (Mus musculus)6480464bisphenol S results in increased expression of FARP1 mRNACTDPMID:30951980 and PMID:39298647
Farp1Rat4,4'-sulfonyldiphenol affects methylationISOFARP1 (Homo sapiens)6480464bisphenol S affects the methylation of FARP1 geneCTDPMID:31601247
Farp1Rat4-hydroxyphenyl retinamide increases expressionISOFarp1 (Mus musculus)6480464Fenretinide results in increased expression of FARP1 mRNACTDPMID:28973697
Farp1Rat4-hydroxyphenyl retinamide decreases expressionISOFarp1 (Mus musculus)6480464Fenretinide results in decreased expression of FARP1 mRNACTDPMID:28973697
Farp1Rat6-propyl-2-thiouracil increases expressionEXP 6480464Propylthiouracil results in increased expression of FARP1 mRNACTDPMID:24780913
Farp1Ratafimoxifene increases expressionISOFARP1 (Homo sapiens)6480464afimoxifene results in increased expression of FARP1 mRNACTDPMID:16849584
Farp1Ratafimoxifene multiple interactionsISOFARP1 (Homo sapiens)6480464ESR2 protein inhibits the reaction [afimoxifene results in increased expression of FARP1 mRNA] more ...CTDPMID:16849584
Farp1Rataflatoxin B1 decreases expressionISOFarp1 (Mus musculus)6480464Aflatoxin B1 results in decreased expression of FARP1 mRNACTDPMID:19770486
Farp1Rataflatoxin B1 increases methylationISOFARP1 (Homo sapiens)6480464Aflatoxin B1 results in increased methylation of FARP1 intronCTDPMID:30157460
Farp1Rataflatoxin B1 decreases methylationISOFARP1 (Homo sapiens)6480464Aflatoxin B1 results in decreased methylation of FARP1 geneCTDPMID:27153756

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Biological Process
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Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Farp1Ratdendrite morphogenesis involved_inIMP 8554251PMID:23209303UniProt 
Farp1Ratenzyme-linked receptor protein signaling pathway involved_inISOFarp1 (Mus musculus)1624291MGI:104683 PMID:14622576RGDPMID:14622576
Farp1Ratenzyme-linked receptor protein signaling pathway involved_inIEAUniProtKB:F8VPU2 and ensembl:ENSMUSP000000266351600115GO_REF:0000107EnsemblGO_REF:0000107
Farp1Ratpositive regulation of skeletal muscle acetylcholine-gated channel clustering involved_inISOFarp1 (Mus musculus)1624291MGI:104683 PMID:14622576RGDPMID:14622576
Farp1Ratpositive regulation of skeletal muscle acetylcholine-gated channel clustering involved_inIEAUniProtKB:F8VPU2 and ensembl:ENSMUSP000000266351600115GO_REF:0000107EnsemblGO_REF:0000107
Farp1Ratpostsynaptic actin cytoskeleton organization involved_inIDA 8554251PMID:23209303SynGO 
Farp1Ratpostsynaptic actin cytoskeleton organization involved_inIMP 8554251PMID:23209303SynGO 
Farp1RatRac protein signal transduction involved_inISOFarp1 (Mus musculus)1624291MGI:88508 PMID:35676269RGDPMID:35676269
Farp1RatRac protein signal transduction involved_inIEAUniProtKB:F8VPU2 and ensembl:ENSMUSP000000266351600115GO_REF:0000107EnsemblGO_REF:0000107
Farp1Ratregulation of presynapse assembly involved_inIMP 8554251PMID:23209303SynGO 
Farp1Ratregulation of presynapse assembly involved_inIDA 8554251PMID:23209303SynGO 
Farp1Ratretrograde trans-synaptic signaling by trans-synaptic protein complex involved_inIMP 8554251PMID:23209303SynGO 
Farp1Ratretrograde trans-synaptic signaling by trans-synaptic protein complex involved_inIDA 8554251PMID:23209303SynGO 
Farp1Ratsynapse assembly involved_inIMP 8554251PMID:23209303UniProt 
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Cellular Component
1 to 20 of 22 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Farp1Ratcell projection located_inIEAUniProtKB-KW:KW-09661600115GO_REF:0000043UniProtGO_REF:0000043
Farp1Ratcytoplasm located_inIEAUniProtKB-KW:KW-09631600115GO_REF:0000043UniProtGO_REF:0000043
Farp1Ratcytoplasmic side of plasma membrane located_inIDA 8554251PMID:23209303UniProt 
Farp1Ratcytoskeleton located_inIEAInterPro:IPR0002991600115GO_REF:0000002InterProGO_REF:0000002
Farp1Ratcytosol located_inIEAUniProtKB-SubCell:SL-00911600115GO_REF:0000044UniProtGO_REF:0000044
Farp1Ratcytosol located_inIDA 8554251PMID:23209303UniProt 
Farp1Ratdendrite located_inIDA 8554251PMID:23209303UniProt 
Farp1Ratdendrite located_inIEAUniProtKB-SubCell:SL-02831600115GO_REF:0000044UniProtGO_REF:0000044
Farp1Ratdendritic spine located_inIEAUniProtKB-SubCell:SL-02841600115GO_REF:0000044UniProtGO_REF:0000044
Farp1Ratextrinsic component of postsynaptic membrane is_active_inIMP 8554251PMID:23209303SynGO 
Farp1Ratextrinsic component of postsynaptic membrane is_active_inIEP 8554251PMID:23209303SynGO 
Farp1Ratextrinsic component of postsynaptic membrane is_active_inIDA 8554251PMID:23209303SynGO 
Farp1Ratfilopodium located_inIEAUniProtKB-SubCell:SL-02861600115GO_REF:0000044UniProtGO_REF:0000044
Farp1Ratglutamatergic synapse is_active_inIMP 8554251PMID:23209303SynGO 
Farp1Ratglutamatergic synapse is_active_inIEP 8554251PMID:23209303SynGO 
Farp1Ratglutamatergic synapse is_active_inIDA 8554251PMID:23209303SynGO 
Farp1Ratmembrane located_inIEAUniProtKB-KW:KW-04721600115GO_REF:0000043UniProtGO_REF:0000043
Farp1Ratneuron projection located_inIEAUniProtKB-KW:KW-07711600115GO_REF:0000043UniProtGO_REF:0000043
Farp1Ratplasma membrane located_inIEAUniProtKB-SubCell:SL-00391600115GO_REF:0000044UniProtGO_REF:0000044
Farp1Ratplasma membrane located_inIEAUniProtKB-KW:KW-10031600115GO_REF:0000043UniProtGO_REF:0000043
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Molecular Function
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1 to 9 of 9 rows


#
Reference Title
Reference Citation
1. The novel synaptogenic protein Farp1 links postsynaptic cytoskeletal dynamics and transsynaptic organization. Cheadle L and Biederer T, J Cell Biol. 2012 Dec 10;199(6):985-1001. doi: 10.1083/jcb.201205041. Epub 2012 Dec 3.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
4. GOA pipeline RGD automated data pipeline
5. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
PMID:19389623   PMID:24899721  



Farp1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr815104,531,196 - 104,770,148 (+)NCBIGRCr8
mRatBN7.21598,124,304 - 98,363,299 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1598,182,329 - 98,363,299 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx15102,114,666 - 102,296,077 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.015103,216,836 - 103,397,759 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.015100,143,970 - 100,325,367 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.015106,375,298 - 106,625,837 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl15106,434,177 - 106,625,837 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.015109,772,475 - 110,020,013 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.415106,171,848 - 106,253,441 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.115106,132,880 - 106,268,432 (+)NCBI
Celera1596,990,113 - 97,147,686 (+)NCBICelera
Cytogenetic Map15q24NCBI
FARP1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381398,142,589 - 98,455,176 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1398,142,562 - 98,455,176 (+)EnsemblGRCh38hg38GRCh38
GRCh371398,794,843 - 99,107,430 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361397,593,435 - 97,900,024 (+)NCBINCBI36Build 36hg18NCBI36
Build 341397,593,434 - 97,900,022NCBI
Celera1379,642,528 - 79,949,414 (+)NCBICelera
Cytogenetic Map13q32.2NCBI
HuRef1379,393,341 - 79,700,014 (+)NCBIHuRef
CHM1_11398,765,676 - 99,072,533 (+)NCBICHM1_1
T2T-CHM13v2.01397,349,662 - 97,662,977 (+)NCBIT2T-CHM13v2.0
Farp1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3914121,272,563 - 121,521,156 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl14121,272,612 - 121,521,156 (+)EnsemblGRCm39 Ensembl
GRCm3814121,035,168 - 121,283,744 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl14121,035,200 - 121,283,744 (+)EnsemblGRCm38mm10GRCm38
MGSCv3714121,434,796 - 121,682,948 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3614120,237,254 - 120,420,973 (+)NCBIMGSCv36mm8
Celera14119,647,443 - 119,834,111 (+)NCBICelera
Cytogenetic Map14E5NCBI
cM Map1464.86NCBI
Farp1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540412,051,591 - 12,317,035 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540412,050,225 - 12,316,842 (-)NCBIChiLan1.0ChiLan1.0
FARP1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21499,657,079 - 99,968,975 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11398,326,502 - 98,641,059 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01379,300,995 - 79,615,649 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11398,452,203 - 98,762,514 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1398,522,235 - 98,761,085 (+)Ensemblpanpan1.1panPan2
FARP1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12248,284,961 - 48,575,007 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2248,342,521 - 48,573,836 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2248,071,250 - 48,356,468 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02248,731,985 - 49,017,180 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2248,732,020 - 49,017,177 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12248,382,095 - 48,667,283 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02248,416,215 - 48,701,436 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02248,452,007 - 48,737,927 (+)NCBIUU_Cfam_GSD_1.0
Farp1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404945183,796,523 - 184,060,923 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647211,887,767 - 12,100,242 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647211,891,234 - 12,100,202 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FARP1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1167,144,645 - 67,457,548 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11167,144,622 - 67,457,547 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21174,553,756 - 74,694,542 (+)NCBISscrofa10.2Sscrofa10.2susScr3
FARP1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1376,807,172 - 77,102,146 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl376,807,211 - 77,100,720 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604633,286,663 - 33,585,234 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Farp1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462479312,592,574 - 12,796,155 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462479312,595,521 - 12,870,803 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

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Variants in Farp1
1784 total Variants

Predicted Target Of
Summary Value
Count of predictions:217
Count of miRNA genes:152
Interacting mature miRNAs:191
Transcripts:ENSRNOT00000015271
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


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The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
731177Uae26Urinary albumin excretion QTL 262.40.025urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)1567588667101769107Rat
1300144Rf23Renal function QTL 233.61renal blood flow trait (VT:2000006)absolute change in renal vascular resistance (CMO:0001900)154063126898288169Rat
1576315Schws6Schwannoma susceptibility QTL 60.0069nervous system integrity trait (VT:0010566)post-insult time of death (CMO:0002005)155380615298806152Rat
1549844Bss7Bone structure and strength QTL 76.4femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)1575788062101769107Rat
2300326Plaw1Placental weight QTL 1150.005placenta mass (VT:0004257)placenta wet weight (CMO:0002088)1568327165100062518Rat
1300118Bp190Blood pressure QTL 1902.94arterial blood pressure trait (VT:2000000)blood pressure measurement (CMO:0000003)158226252098288169Rat
1358354Srcrt5Stress Responsive Cort QTL 53.38blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)159815000199043291Rat
70155Gcs1Gastric cancer susceptibility QTL13.8stomach morphology trait (VT:0000470)stomach tumor susceptibility score (CMO:0002043)1576306099101769107Rat
1300120Kidm7Kidney mass QTL 73.55kidney mass (VT:0002707)left kidney wet weight to body weight ratio (CMO:0001954)158226252098288169Rat
1578646Bmd18Bone mineral density QTL 185.2femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)152280624098288169Rat

1 to 10 of 15 rows
D15Rat106  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr815104,694,807 - 104,695,021 (+)Marker Load Pipeline
mRatBN7.21598,287,955 - 98,288,169 (+)MAPPERmRatBN7.2
Rnor_6.015106,550,444 - 106,550,657NCBIRnor6.0
Rnor_5.015109,944,744 - 109,944,957UniSTSRnor5.0
RGSC_v3.415106,177,703 - 106,177,917RGDRGSC3.4
RGSC_v3.415106,177,704 - 106,177,917UniSTSRGSC3.4
RGSC_v3.115106,193,484 - 106,193,697RGD
Celera1597,072,390 - 97,072,603UniSTS
RH 3.4 Map15688.5UniSTS
RH 3.4 Map15688.5RGD
SHRSP x BN Map1565.3898UniSTS
SHRSP x BN Map1565.3898RGD
FHH x ACI Map1574.04RGD
Cytogenetic Map15q24-q25UniSTS
AW228844  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21598,362,898 - 98,362,996 (+)MAPPERmRatBN7.2
Rnor_6.015106,625,437 - 106,625,534NCBIRnor6.0
Rnor_5.015110,019,613 - 110,019,710UniSTSRnor5.0
RGSC_v3.415106,253,041 - 106,253,138UniSTSRGSC3.4
Celera1597,147,286 - 97,147,383UniSTS
Cytogenetic Map15q24-q25UniSTS
BE116755  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21598,307,851 - 98,308,028 (+)MAPPERmRatBN7.2
Rnor_6.015106,570,339 - 106,570,515NCBIRnor6.0
Rnor_5.015109,964,515 - 109,964,691UniSTSRnor5.0
RGSC_v3.415106,198,014 - 106,198,190UniSTSRGSC3.4
Celera1597,092,171 - 97,092,347UniSTS
RH 3.4 Map15691.5UniSTS
Cytogenetic Map15q24-q25UniSTS
RH138289  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21598,329,592 - 98,329,768 (+)MAPPERmRatBN7.2
Rnor_6.015106,592,079 - 106,592,254NCBIRnor6.0
Rnor_5.015109,986,255 - 109,986,430UniSTSRnor5.0
RGSC_v3.415106,219,753 - 106,219,928UniSTSRGSC3.4
Celera1597,113,923 - 97,114,098UniSTS
RH 3.4 Map15690.3UniSTS
Cytogenetic Map15q24-q25UniSTS
RH139121  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21598,327,184 - 98,327,340 (+)MAPPERmRatBN7.2
Rnor_6.015106,589,670 - 106,589,825NCBIRnor6.0
Rnor_5.015109,983,846 - 109,984,001UniSTSRnor5.0
RGSC_v3.415106,217,345 - 106,217,500UniSTSRGSC3.4
Celera1597,111,515 - 97,111,670UniSTS
RH 3.4 Map15690.21UniSTS
Cytogenetic Map15q24-q25UniSTS
RH139138  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21598,330,204 - 98,330,453 (+)MAPPERmRatBN7.2
Rnor_6.015106,592,691 - 106,592,939NCBIRnor6.0
Rnor_5.015109,986,867 - 109,987,115UniSTSRnor5.0
RGSC_v3.415106,220,365 - 106,220,613UniSTSRGSC3.4
Celera1597,114,535 - 97,114,783UniSTS
RH 3.4 Map15738.99UniSTS
Cytogenetic Map15q24-q25UniSTS
RH141737  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21598,362,040 - 98,362,222 (+)MAPPERmRatBN7.2
Rnor_6.015106,624,579 - 106,624,760NCBIRnor6.0
Rnor_5.015110,018,755 - 110,018,936UniSTSRnor5.0
RGSC_v3.415106,252,183 - 106,252,364UniSTSRGSC3.4
Celera1597,146,428 - 97,146,609UniSTS
RH 3.4 Map15691.3UniSTS
Cytogenetic Map15q24-q25UniSTS
AI229437  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21598,215,978 - 98,216,160 (+)MAPPERmRatBN7.2
Rnor_6.015106,468,712 - 106,468,893NCBIRnor6.0
Rnor_5.015109,863,239 - 109,863,420UniSTSRnor5.0
Celera1597,023,167 - 97,023,348UniSTS
RH 3.4 Map15689.0UniSTS
Cytogenetic Map15q24-q25UniSTS
BE107531  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21598,240,781 - 98,240,931 (+)MAPPERmRatBN7.2
Rnor_6.015106,493,387 - 106,493,536NCBIRnor6.0
Rnor_5.015109,887,914 - 109,888,063UniSTSRnor5.0
Celera1597,047,967 - 97,048,116UniSTS
RH 3.4 Map15690.9UniSTS
Cytogenetic Map15q24-q25UniSTS




alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31



Ensembl Acc Id: ENSRNOT00000015271   ⟹   ENSRNOP00000015271
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1598,182,329 - 98,363,299 (+)Ensembl
Rnor_6.0 Ensembl15106,434,177 - 106,625,837 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000098108   ⟹   ENSRNOP00000080871
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1598,182,329 - 98,363,299 (+)Ensembl
RefSeq Acc Id: NM_001107287   ⟹   NP_001100757
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr815104,589,185 - 104,770,148 (+)NCBI
mRatBN7.21598,182,329 - 98,363,299 (+)NCBI
Rnor_6.015106,434,177 - 106,625,837 (+)NCBI
Rnor_5.015109,772,475 - 110,020,013 (+)NCBI
RGSC_v3.415106,171,848 - 106,253,441 (+)RGD
Celera1596,990,113 - 97,147,686 (+)RGD
Sequence:
RefSeq Acc Id: XM_006252472   ⟹   XP_006252534
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr815104,531,836 - 104,770,146 (+)NCBI
mRatBN7.21598,124,973 - 98,363,298 (+)NCBI
Rnor_6.015106,376,421 - 106,625,836 (+)NCBI
Rnor_5.015109,772,475 - 110,020,013 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006252475   ⟹   XP_006252537
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr815104,531,836 - 104,770,146 (+)NCBI
mRatBN7.21598,124,973 - 98,363,298 (+)NCBI
Rnor_6.015106,376,421 - 106,625,836 (+)NCBI
Rnor_5.015109,772,475 - 110,020,013 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017599720   ⟹   XP_017455209
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr815104,531,196 - 104,770,146 (+)NCBI
mRatBN7.21598,124,304 - 98,363,298 (+)NCBI
Rnor_6.015106,375,298 - 106,625,836 (+)NCBI
Sequence:
RefSeq Acc Id: XM_063274357   ⟹   XP_063130427
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr815104,733,523 - 104,770,146 (+)NCBI
RefSeq Acc Id: XM_063274358   ⟹   XP_063130428
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr815104,733,523 - 104,770,146 (+)NCBI
1 to 10 of 10 rows
Protein RefSeqs NP_001100757 (Get FASTA)   NCBI Sequence Viewer  
  XP_006252534 (Get FASTA)   NCBI Sequence Viewer  
  XP_006252537 (Get FASTA)   NCBI Sequence Viewer  
  XP_017455209 (Get FASTA)   NCBI Sequence Viewer  
  XP_063130427 (Get FASTA)   NCBI Sequence Viewer  
  XP_063130428 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDM02559 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000015271
  ENSRNOP00000015271.5
GenBank Protein F1LYQ8 (Get FASTA)   NCBI Sequence Viewer  
1 to 10 of 10 rows
RefSeq Acc Id: NP_001100757   ⟸   NM_001107287
- UniProtKB: F1LYQ8 (UniProtKB/Swiss-Prot),   A0A8I5ZQU0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006252534   ⟸   XM_006252472
- Peptide Label: isoform X1
- UniProtKB: F1LYQ8 (UniProtKB/Swiss-Prot),   A0A8I5ZQU0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006252537   ⟸   XM_006252475
- Peptide Label: isoform X2
- UniProtKB: A0A8I5ZQU0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017455209   ⟸   XM_017599720
- Peptide Label: isoform X1
- UniProtKB: F1LYQ8 (UniProtKB/Swiss-Prot),   A0A8I5ZQU0 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000015271   ⟸   ENSRNOT00000015271
DH   FERM   PH

Name Modeler Protein Id AA Range Protein Structure
AF-F1LYQ8-F1-model_v2 AlphaFold F1LYQ8 1-1049 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen



1 to 40 of 54 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-12380 BioCyc
Ensembl Genes ENSRNOG00000011203 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000015271 ENTREZGENE
  ENSRNOT00000015271.7 UniProtKB/Swiss-Prot
Gene3D-CATH 1.20.80.10 UniProtKB/Swiss-Prot
  1.20.900.10 UniProtKB/Swiss-Prot
  2.30.29.30 UniProtKB/Swiss-Prot
  Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1 UniProtKB/Swiss-Prot
InterPro Band_41_domain UniProtKB/Swiss-Prot
  DBL_dom_sf UniProtKB/Swiss-Prot
  DH-domain UniProtKB/Swiss-Prot
  Ez/rad/moesin-like UniProtKB/Swiss-Prot
  FARP1/FARP2/FRMD7_FERM_C UniProtKB/Swiss-Prot
  FERM-adjacent UniProtKB/Swiss-Prot
  FERM/acyl-CoA-bd_prot_sf UniProtKB/Swiss-Prot
  FERM_2 UniProtKB/Swiss-Prot
  FERM_central UniProtKB/Swiss-Prot
  FERM_CS UniProtKB/Swiss-Prot
  FERM_domain UniProtKB/Swiss-Prot
  FERM_N UniProtKB/Swiss-Prot
  FERM_PH-like_C UniProtKB/Swiss-Prot
  PH-like_dom_sf UniProtKB/Swiss-Prot
  PH_domain UniProtKB/Swiss-Prot
  RAC1-GEF UniProtKB/Swiss-Prot
  Ubiquitin-like_domsf UniProtKB/Swiss-Prot
KEGG Report rno:306183 UniProtKB/Swiss-Prot
NCBI Gene 306183 ENTREZGENE
PANTHER FERM DOMAIN CONTAINING PROTEIN UniProtKB/Swiss-Prot
  FERM, ARHGEF AND PLECKSTRIN DOMAIN-CONTAINING PROTEIN 1 UniProtKB/Swiss-Prot
Pfam FERM_C UniProtKB/Swiss-Prot
  FERM_M UniProtKB/Swiss-Prot
  FERM_N UniProtKB/Swiss-Prot
  PF00169 UniProtKB/Swiss-Prot
  PF08736 UniProtKB/Swiss-Prot
  RhoGEF UniProtKB/Swiss-Prot
PhenoGen Farp1 PhenoGen
PRINTS BAND41 UniProtKB/Swiss-Prot
  ERMFAMILY UniProtKB/Swiss-Prot
PROSITE DH_2 UniProtKB/Swiss-Prot
  FERM_1 UniProtKB/Swiss-Prot
1 to 40 of 54 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-11-19 Farp1  FERM, ARH/RhoGEF and pleckstrin domain protein 1  Farp1  FERM, RhoGEF (Arhgef) and pleckstrin domain protein 1 (chondrocyte-derived)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2013-05-24 Farp1  FERM, RhoGEF (Arhgef) and pleckstrin domain protein 1 (chondrocyte-derived)  LOC100361560  FERMRhoGEF (Arhgef) and pleckstrin domain protein 1-like  Data merged from RGD:2319908 1643240 APPROVED
2010-05-05 LOC100361560  FERMRhoGEF (Arhgef) and pleckstrin domain protein 1-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2008-04-30 Farp1  FERM, RhoGEF (Arhgef) and pleckstrin domain protein 1 (chondrocyte-derived)   Farp1_predicted  FERM, RhoGEF (Arhgef) and pleckstrin domain protein 1 (chondrocyte-derived) (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Farp1_predicted  FERM, RhoGEF (Arhgef) and pleckstrin domain protein 1 (chondrocyte-derived) (predicted)      Symbol and Name status set to approved 70820 APPROVED