Farp1 (FERM, ARH/RhoGEF and pleckstrin domain protein 1) - Rat Genome Database

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Gene: Farp1 (FERM, ARH/RhoGEF and pleckstrin domain protein 1) Heterocephalus glaber
Analyze
Symbol: Farp1
Name: FERM, ARH/RhoGEF and pleckstrin domain protein 1
RGD ID: 18921984
Description: ENCODES a protein that exhibits small GTPase binding (ortholog); INVOLVED IN dendrite morphogenesis (ortholog); enzyme-linked receptor protein signaling pathway (ortholog); positive regulation of skeletal muscle acetylcholine-gated channel clustering (ortholog); ASSOCIATED WITH Anal Atresia, Hypospadias, and Penoscrotal Inversion (ortholog); genetic disease (ortholog); holoprosencephaly 5 (ortholog); FOUND IN cytoplasmic side of plasma membrane (ortholog); extrinsic component of postsynaptic membrane (ortholog); glutamatergic synapse (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: FERM, RhoGEF and pleckstrin domain-containing protein 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462479312,592,574 - 12,796,155 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462479312,595,521 - 12,870,803 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Farp1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462479312,592,574 - 12,796,155 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462479312,595,521 - 12,870,803 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
FARP1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381398,142,589 - 98,455,176 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1398,142,562 - 98,455,176 (+)EnsemblGRCh38hg38GRCh38
GRCh371398,794,843 - 99,107,430 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361397,593,435 - 97,900,024 (+)NCBINCBI36Build 36hg18NCBI36
Build 341397,593,434 - 97,900,022NCBI
Celera1379,642,528 - 79,949,414 (+)NCBICelera
Cytogenetic Map13q32.2NCBI
HuRef1379,393,341 - 79,700,014 (+)NCBIHuRef
CHM1_11398,765,676 - 99,072,533 (+)NCBICHM1_1
T2T-CHM13v2.01397,349,662 - 97,662,977 (+)NCBIT2T-CHM13v2.0
Farp1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3914121,272,563 - 121,521,156 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl14121,272,612 - 121,521,156 (+)EnsemblGRCm39 Ensembl
GRCm3814121,035,168 - 121,283,744 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl14121,035,200 - 121,283,744 (+)EnsemblGRCm38mm10GRCm38
MGSCv3714121,434,796 - 121,682,948 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3614120,237,254 - 120,420,973 (+)NCBIMGSCv36mm8
Celera14119,647,443 - 119,834,111 (+)NCBICelera
Cytogenetic Map14E5NCBI
cM Map1464.86NCBI
Farp1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr815104,531,196 - 104,770,148 (+)NCBIGRCr8
mRatBN7.21598,124,304 - 98,363,299 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1598,182,329 - 98,363,299 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx15102,114,666 - 102,296,077 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.015103,216,836 - 103,397,759 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.015100,143,970 - 100,325,367 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.015106,375,298 - 106,625,837 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl15106,434,177 - 106,625,837 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.015109,772,475 - 110,020,013 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.415106,171,848 - 106,253,441 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.115106,132,880 - 106,268,432 (+)NCBI
Celera1596,990,113 - 97,147,686 (+)NCBICelera
Cytogenetic Map15q24NCBI
Farp1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540412,051,591 - 12,317,035 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540412,050,225 - 12,316,842 (-)NCBIChiLan1.0ChiLan1.0
FARP1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21499,657,079 - 99,968,975 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11398,326,502 - 98,641,059 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01379,300,995 - 79,615,649 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11398,452,203 - 98,762,514 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1398,522,235 - 98,761,085 (+)Ensemblpanpan1.1panPan2
FARP1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12248,284,961 - 48,575,007 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2248,342,521 - 48,573,836 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2248,071,250 - 48,356,468 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02248,731,985 - 49,017,180 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2248,732,020 - 49,017,177 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12248,382,095 - 48,667,283 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02248,416,215 - 48,701,436 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02248,452,007 - 48,737,927 (+)NCBIUU_Cfam_GSD_1.0
Farp1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404945183,796,523 - 184,060,923 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647211,887,767 - 12,100,242 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647211,891,234 - 12,100,202 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FARP1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1167,144,645 - 67,457,548 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11167,144,622 - 67,457,547 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21174,553,756 - 74,694,542 (+)NCBISscrofa10.2Sscrofa10.2susScr3
FARP1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1376,807,172 - 77,102,146 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl376,807,211 - 77,100,720 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604633,286,663 - 33,585,234 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSHGLT00000027689   ⟹   ENSHGLP00000027446
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462479312,592,574 - 12,796,155 (-)Ensembl
RefSeq Acc Id: XM_004858630   ⟹   XP_004858687
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462479312,595,521 - 12,870,802 (-)NCBI
RefSeq Acc Id: XM_004858631   ⟹   XP_004858688
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462479312,595,521 - 12,870,803 (-)NCBI
RefSeq Acc Id: XM_004858632   ⟹   XP_004858689
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462479312,595,521 - 12,870,802 (-)NCBI
RefSeq Acc Id: XM_021239366   ⟹   XP_021095025
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462479312,595,521 - 12,869,537 (-)NCBI
RefSeq Acc Id: XM_021239367   ⟹   XP_021095026
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462479312,595,521 - 12,863,666 (-)NCBI
RefSeq Acc Id: XM_021239368   ⟹   XP_021095027
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462479312,595,521 - 12,870,802 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_004858688   ⟸   XM_004858631
- Peptide Label: isoform X2
- UniProtKB: G5C351 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021095027   ⟸   XM_021239368
- Peptide Label: isoform X4
- UniProtKB: G5C351 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004858689   ⟸   XM_004858632
- Peptide Label: isoform X3
- UniProtKB: G5C351 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004858687   ⟸   XM_004858630
- Peptide Label: isoform X1
- UniProtKB: A0A0P6JBA0 (UniProtKB/TrEMBL),   G5C351 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021095025   ⟸   XM_021239366
- Peptide Label: isoform X1
- UniProtKB: A0A0P6JBA0 (UniProtKB/TrEMBL),   G5C351 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021095026   ⟸   XM_021239367
- Peptide Label: isoform X1
- UniProtKB: A0A0P6JBA0 (UniProtKB/TrEMBL),   G5C351 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSHGLP00000027446   ⟸   ENSHGLT00000027689


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000019518 Ensembl, ENTREZGENE
  ENSHGLG00100000777 UniProtKB/TrEMBL
Ensembl Transcript ENSHGLT00000027689 ENTREZGENE
  ENSHGLT00100000991 UniProtKB/TrEMBL
Gene3D-CATH 1.20.80.10 UniProtKB/TrEMBL
  1.20.900.10 UniProtKB/TrEMBL
  2.30.29.30 UniProtKB/TrEMBL
InterPro Band_41_domain UniProtKB/TrEMBL
  DBL_dom_sf UniProtKB/TrEMBL
  DH-domain UniProtKB/TrEMBL
  Ez/rad/moesin-like UniProtKB/TrEMBL
  FARP1/FARP2/FRMD7_FERM_C UniProtKB/TrEMBL
  FERM-adjacent UniProtKB/TrEMBL
  FERM/acyl-CoA-bd_prot_sf UniProtKB/TrEMBL
  FERM_2 UniProtKB/TrEMBL
  FERM_central UniProtKB/TrEMBL
  FERM_CS UniProtKB/TrEMBL
  FERM_domain UniProtKB/TrEMBL
  FERM_N UniProtKB/TrEMBL
  FERM_PH-like_C UniProtKB/TrEMBL
  PH-like_dom_sf UniProtKB/TrEMBL
  PH_domain UniProtKB/TrEMBL
  Ubiquitin-like_domsf UniProtKB/TrEMBL
KEGG Report hgl:101717806 UniProtKB/TrEMBL
NCBI Gene Farp1 ENTREZGENE
PANTHER FERM DOMAIN CONTAINING PROTEIN UniProtKB/TrEMBL
  FERM, ARHGEF AND PLECKSTRIN DOMAIN-CONTAINING PROTEIN 1 UniProtKB/TrEMBL
Pfam FERM_C UniProtKB/TrEMBL
  FERM_M UniProtKB/TrEMBL
  FERM_N UniProtKB/TrEMBL
  PF00169 UniProtKB/TrEMBL
  PF08736 UniProtKB/TrEMBL
  RhoGEF UniProtKB/TrEMBL
PRINTS BAND41 UniProtKB/TrEMBL
  ERMFAMILY UniProtKB/TrEMBL
PROSITE DH_2 UniProtKB/TrEMBL
  FERM_1 UniProtKB/TrEMBL
  FERM_3 UniProtKB/TrEMBL
  PH_DOMAIN UniProtKB/TrEMBL
SMART B41 UniProtKB/TrEMBL
  FERM_C UniProtKB/TrEMBL
  RhoGEF UniProtKB/TrEMBL
  SM00233 UniProtKB/TrEMBL
  SM01195 UniProtKB/TrEMBL
Superfamily-SCOP PH domain-like UniProtKB/TrEMBL
  SSF47031 UniProtKB/TrEMBL
  SSF48065 UniProtKB/TrEMBL
  SSF54236 UniProtKB/TrEMBL
UniProt A0A0P6JBA0 ENTREZGENE, UniProtKB/TrEMBL
  G5C351 ENTREZGENE, UniProtKB/TrEMBL