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Gene: Skp2 (S-phase kinase associated protein 2) Chinchilla lanigera

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Symbol:

Skp2

Name:

S-phase kinase associated protein 2

RGD ID:

8910470

Description:

ENCODES a protein that exhibits identical protein binding (ortholog); ubiquitin-like ligase-substrate adaptor activity (ortholog); INVOLVED IN cellular response to cell-matrix adhesion (ortholog); defense response to virus (ortholog); G1/S transition of mitotic cell cycle (ortholog); PARTICIPATES IN Notch signaling pathway; p53 signaling pathway; ASSOCIATED WITH Brain Injuries (ortholog); breast cancer (ortholog); cervix uteri carcinoma in situ (ortholog); FOUND IN cytosol (ortholog); nucleolus (ortholog); nucleoplasm (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

S-phase kinase-associated protein 2; S-phase kinase-associated protein 2, E3 ubiquitin protein ligase

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

ChiLan1.0 - Chinchilla ChiLan1.0 Assembly

Position:

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955426	20,972,663 - 20,999,769 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955426	20,972,663 - 20,999,769 (+)	NCBI	ChiLan1.0	ChiLan1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Skp2	Chinchilla	Brain Injuries		ISO	RGD:1562456	9068941	protein:increased expression:brain	RGD	PMID:19852587\|REF_RGD_ID:2315049
Skp2	Chinchilla	breast cancer		ISO	RGD:1607086	9068941	protein:increased expression:breast	RGD	PMID:19350629\|REF_RGD_ID:2315035
Skp2	Chinchilla	cervix uteri carcinoma in situ	severity	ISO	RGD:1607086	9068941	associated with Papillomavirus Infections	RGD	PMID:19094580\|REF_RGD_ID:2315036
Skp2	Chinchilla	endometrial hyperplasia		ISO	RGD:1607086	9068941	associated with Endometrial Neoplasms;protein:increased expression:endometrium	RGD	PMID:16080017\|REF_RGD_ID:2315043
Skp2	Chinchilla	Endometrial Neoplasms		ISO	RGD:1607086	9068941		RGD	PMID:15220466\|REF_RGD_ID:2315045
Skp2	Chinchilla	hepatocellular carcinoma		ISO	RGD:1562456	9068941	protein:increased expression:liver	RGD	PMID:19533683\|REF_RGD_ID:2315050
Skp2	Chinchilla	lung small cell carcinoma		ISO	RGD:1607086	9068941	mRNA:increased expression:lung:	RGD	PMID:12107105\|REF_RGD_ID:13825152
Skp2	Chinchilla	Lymphatic Metastasis		ISO	RGD:1607086	9068941	associated with Endometrial Neoplasms;protein:increased expression:endometrium	RGD	PMID:16080017\|REF_RGD_ID:2315043
Skp2	Chinchilla	oral squamous cell carcinoma		ISO	RGD:1607086	9068941	protein:increased expression:mucosa of oral region (human)	RGD	PMID:24743017\|REF_RGD_ID:151665336
Skp2	Chinchilla	Ovarian Neoplasms	disease_progression	ISO	RGD:1607086	9068941		RGD	PMID:16525656\|REF_RGD_ID:2315042
Skp2	Chinchilla	prostate cancer	disease_progression	ISO	RGD:1607086	9068941		RGD	PMID:19450994\|REF_RGD_ID:2315029
Skp2	Chinchilla	prostate carcinoma		ISO	RGD:1607086	9068941		RGD	PMID:12670908\|REF_RGD_ID:2315046
Skp2	Chinchilla	renal cell carcinoma	disease_progression	ISO	RGD:1607086	9068941		RGD	PMID:18922157\|REF_RGD_ID:2315038
Skp2	Chinchilla	transitional cell carcinoma	disease_progression	ISO	RGD:1607086	9068941	protein:increased expression:kidney	RGD	PMID:15351619\|REF_RGD_ID:2315044
Skp2	Chinchilla	Uterine Cervical Neoplasms	disease_progression	ISO	RGD:1607086	9068941	associated with Papillomavirus Infections	RGD	PMID:19094580\|REF_RGD_ID:2315036
Skp2	Chinchilla	Uterine Cervical Neoplasms		ISO	RGD:1607086	9068941	DNA, mRNA:amplification, increased expression:uterine cervix	RGD	PMID:18559093\|REF_RGD_ID:2302384

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Skp2	Chinchilla	Neurodevelopmental Disorders		ISO	RGD:1607086	8554872	ClinVar Annotator: match by term: Neurodevelopmental disorder	ClinVar	PMID:25741868

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Skp2	Chinchilla	diffuse large B-cell lymphoma		ISO	RGD:1607086	9068941	CTD Direct Evidence: marker/mechanism	CTD	PMID:18850583
Skp2	Chinchilla	disease of cellular proliferation		ISO	RGD:1607086	9068941	CTD Direct Evidence: marker/mechanism	CTD	PMID:18451165
Skp2	Chinchilla	hepatocellular carcinoma		ISO	RGD:1607086	9068941	CTD Direct Evidence: marker/mechanism	CTD	PMID:12717389
Skp2	Chinchilla	medulloblastoma		ISO	RGD:1607086	9068941	CTD Direct Evidence: marker/mechanism	CTD	PMID:19270706
Skp2	Chinchilla	Ovarian Neoplasms		ISO	RGD:1607086	9068941	CTD Direct Evidence: marker/mechanism	CTD	PMID:19636294
Skp2	Chinchilla	Spine Osteoarthritis		ISO	RGD:1607086	9068941	CTD Direct Evidence: marker/mechanism	CTD	PMID:34697729

Biological Process

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Skp2	Chinchilla	cellular response to cell-matrix adhesion		ISO	RGD:1562456	9068941		RGD	PMID:11425869\|REF_RGD_ID:2315071
Skp2	Chinchilla	defense response to virus	involved_in	ISO	RGD:1607086	9068941	PMID:27194766	UniProt	PMID:27194766
Skp2	Chinchilla	G1/S transition of mitotic cell cycle	acts_upstream_of_or_within	ISO	RGD:1552631	9068941	PMID:10790373	MGI	PMID:10790373
Skp2	Chinchilla	G2/M transition of mitotic cell cycle	acts_upstream_of_or_within	ISO	RGD:1552631	9068941	PMID:19056892	MGI	PMID:19056892
Skp2	Chinchilla	G2/M transition of mitotic cell cycle	acts_upstream_of_or_within	ISO	MGI:108061	9068941	PMID:19056892	MGI	PMID:19056892
Skp2	Chinchilla	innate immune response	involved_in	ISO	RGD:1607086	9068941	PMID:27194766	UniProt	PMID:27194766
Skp2	Chinchilla	positive regulation of double-strand break repair via homologous recombination	involved_in	ISO	RGD:1552631	9068941	PMID:22464731	UniProt	PMID:22464731
Skp2	Chinchilla	positive regulation of double-strand break repair via homologous recombination	involved_in	ISO	RGD:1607086	9068941	PMID:22464731	UniProt	PMID:22464731
Skp2	Chinchilla	positive regulation of intracellular estrogen receptor signaling pathway	acts_upstream_of_or_within	ISO	MGI:102520	9068941	PMID:17785450	MGI	PMID:17785450
Skp2	Chinchilla	positive regulation of protein polyubiquitination	acts_upstream_of_or_within	ISO	RGD:1552631	9068941	PMID:23277542	MGI	PMID:23277542
Skp2	Chinchilla	positive regulation of smooth muscle cell proliferation		ISO	RGD:1562456	9068941		RGD	PMID:19878790\|REF_RGD_ID:2315048
Skp2	Chinchilla	proteasome-mediated ubiquitin-dependent protein catabolic process	involved_in	ISO	RGD:1607086	9068941	PMID:27194766	UniProt	PMID:27194766
Skp2	Chinchilla	protein K48-linked ubiquitination	involved_in	ISO	RGD:1607086	9068941	PMID:27194766	UniProt	PMID:27194766
Skp2	Chinchilla	protein K63-linked ubiquitination	involved_in	ISO	RGD:1552631	9068941	PMID:22464731	UniProt	PMID:22464731
Skp2	Chinchilla	protein K63-linked ubiquitination	involved_in	ISO	RGD:1607086	9068941	PMID:22464731	UniProt	PMID:22464731
Skp2	Chinchilla	protein polyubiquitination	acts_upstream_of_or_within	ISO	RGD:1552631	9068941	PMID:17785450	MGI	PMID:17785450
Skp2	Chinchilla	regulation of apoptotic process	acts_upstream_of_or_within	ISO	RGD:1607086	9068941	PMID:23277542	MGI	PMID:23277542
Skp2	Chinchilla	regulation of cell cycle	acts_upstream_of_or_within	ISO	PR:Q61457	9068941	PMID:10790373	MGI	PMID:10790373
Skp2	Chinchilla	ubiquitin-dependent protein catabolic process	acts_upstream_of_or_within	ISO	RGD:1552631	9068941	PMID:19056892	MGI	PMID:19056892
Skp2	Chinchilla	ubiquitin-dependent protein catabolic process	acts_upstream_of_or_within	ISO	RGD:1552631	9068941	PMID:10790373	MGI	PMID:10790373

Cellular Component

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Skp2	Chinchilla	cytosol	located_in	ISO	RGD:1607086	9068941		HPA	GO_REF:0000052
Skp2	Chinchilla	nucleolus	located_in	ISO	RGD:1607086	9068941		HPA	GO_REF:0000052
Skp2	Chinchilla	nucleoplasm	located_in	ISO	RGD:1607086	9068941		HPA	GO_REF:0000052
Skp2	Chinchilla	SCF ubiquitin ligase complex	part_of	ISO	RGD:1552631	9068941	PMID:17785450, PMID:22464731	MGI	PMID:17785450\|PMID:22464731
Skp2	Chinchilla	SCF ubiquitin ligase complex	part_of	ISO	RGD:1607086	9068941	PMID:16880511, PMID:22464731	UniProt	PMID:16880511\|PMID:22464731

Molecular Function

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Skp2	Chinchilla	identical protein binding	enables	ISO	UniProtKB:Q13309	9068941	PMID:22770219	IntAct	PMID:22770219
Skp2	Chinchilla	protein binding	enables	ISO	UniProtKB:P19474	9068941	PMID:16880511	UniProt	PMID:16880511
Skp2	Chinchilla	protein binding	enables	ISO	PR:P01108	9068941	PMID:23277542	MGI	PMID:23277542
Skp2	Chinchilla	protein binding	enables	ISO	PR:P62878\|PR:Q9WTX5\|PR:Q9WTX6	9068941	PMID:19398581	MGI	PMID:19398581
Skp2	Chinchilla	protein binding	enables	ISO	UniProtKB:P63208\|UniProtKB:Q13616	9068941	PMID:12609982	IntAct	PMID:12609982
Skp2	Chinchilla	protein binding	enables	ISO	UniProtKB:P09803\|UniProtKB:Q09472\|UniProtKB:Q9NTG7\|UniProtKB:Q9UM11	9068941	PMID:22770219	IntAct	PMID:22770219
Skp2	Chinchilla	protein binding	enables	ISO	UniProtKB:P61024\|UniProtKB:Q13616	9068941	PMID:28514442	IntAct	PMID:28514442
Skp2	Chinchilla	protein binding	enables	ISO	UniProtKB:P38936\|UniProtKB:P63208\|UniProtKB:Q4AE16	9068941	PMID:16376880	IntAct	PMID:16376880
Skp2	Chinchilla	protein binding	enables	ISO	UniProtKB:P46527\|UniProtKB:P61024	9068941	PMID:16209941	IntAct	PMID:16209941
Skp2	Chinchilla	protein binding	enables	ISO	UniProtKB:P46527	9068941	PMID:18805092	IntAct	PMID:18805092
Skp2	Chinchilla	protein binding	enables	ISO	UniProtKB:P46527\|UniProtKB:P63208	9068941	PMID:22632967	IntAct	PMID:22632967
Skp2	Chinchilla	protein binding	enables	ISO	UniProtKB:A5D8W4\|UniProtKB:P61024\|UniProtKB:P62877\|UniProtKB:P63208\|UniProtKB:Q13616	9068941	PMID:18239684	IntAct	PMID:18239684
Skp2	Chinchilla	protein binding	enables	ISO	UniProtKB:Q13616	9068941	PMID:12504026, PMID:21145461, PMID:27542266	IntAct	PMID:12504026\|PMID:21145461\|PMID:27542266
Skp2	Chinchilla	protein binding	enables	ISO	UniProtKB:P38936	9068941	PMID:25241761, PMID:30833792	IntAct	PMID:25241761\|PMID:30833792
Skp2	Chinchilla	protein binding	enables	ISO	UniProtKB:P61024\|UniProtKB:P63208	9068941	PMID:12813041	IntAct	PMID:12813041
Skp2	Chinchilla	protein binding	enables	ISO	UniProtKB:Q13415	9068941	PMID:11931757	IntAct	PMID:11931757
Skp2	Chinchilla	protein binding	enables	ISO	UniProtKB:P35232	9068941	PMID:20134482	IntAct	PMID:20134482
Skp2	Chinchilla	protein binding	enables	ISO	UniProtKB:P27958	9068941	PMID:27194766	UniProt	PMID:27194766
Skp2	Chinchilla	protein binding		ISO	RGD:69062	9068941		RGD	PMID:19852587\|REF_RGD_ID:2315049
Skp2	Chinchilla	protein binding		ISO	RGD:727892	9068941		RGD	PMID:19533683\|REF_RGD_ID:2315050
Skp2	Chinchilla	protein binding		ISO	RGD:3541	9068941		RGD	PMID:19533683\|REF_RGD_ID:2315050
Skp2	Chinchilla	protein binding		ISO	RGD:69328	9068941		RGD	PMID:19533683\|REF_RGD_ID:2315050
Skp2	Chinchilla	protein binding		ISO	RGD:1359383	9068941		RGD	PMID:19533683\|REF_RGD_ID:2315050
Skp2	Chinchilla	protein binding	enables	ISO	UniProtKB:Q96Q27	9068941	PMID:21119685	UniProt	PMID:21119685
Skp2	Chinchilla	protein binding	enables	ISO	UniProtKB:P63208-1	9068941	PMID:11099048, PMID:18667692	IntAct	PMID:11099048\|PMID:18667692
Skp2	Chinchilla	protein binding	enables	ISO	UniProtKB:P28562	9068941	PMID:16286470	IntAct	PMID:16286470
Skp2	Chinchilla	protein binding	enables	ISO	UniProtKB:P63208	9068941	PMID:18818696, PMID:23911321, PMID:27705803, PMID:29997244, PMID:31467278, PMID:37398436	IntAct	PMID:18818696\|PMID:23911321\|PMID:27705803\|PMID:29997244\|PMID:31467278\|PMID:37398436
Skp2	Chinchilla	protein binding	enables	ISO	UniProtKB:P38936\|UniProtKB:P61024\|UniProtKB:P62877\|UniProtKB:P63208\|UniProtKB:Q9UM11	9068941	PMID:33961781	IntAct	PMID:33961781
Skp2	Chinchilla	protein binding	enables	ISO	PR:O35129	9068941	PMID:17785450	MGI	PMID:17785450
Skp2	Chinchilla	protein binding	enables	ISO	UniProtKB:P12004,UniProtKB:Q9H211	9068941	PMID:21856198	CAFA	PMID:21856198
Skp2	Chinchilla	protein binding	enables	ISO	UniProtKB:Q03164	9068941	PMID:20818375	IntAct	PMID:20818375
Skp2	Chinchilla	protein binding	enables	ISO	UniProtKB:P01106	9068941	PMID:17157259	IntAct	PMID:17157259
Skp2	Chinchilla	ubiquitin-like ligase-substrate adaptor activity	enables	ISO	RGD:1552631	9068941	PMID:22464731	UniProt	PMID:22464731
Skp2	Chinchilla	ubiquitin-like ligase-substrate adaptor activity	enables	ISO	RGD:1607086	9068941	PMID:22464731	UniProt	PMID:22464731

Imported Annotations - PID (archival)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Skp2	Chinchilla	Notch signaling pathway		ISO	RGD:1607086	9068941		PID	PID:200015
Skp2	Chinchilla	p53 signaling pathway		ISO	RGD:1607086	9068941		PID	PID:200206

#	Reference Title	Reference Citation
1.	Transitive Annotation Pipeline	Automated assignment of GO, PW and RDO ISO annotations across species

PMID:22301074

Skp2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955426	20,972,663 - 20,999,769 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955426	20,972,663 - 20,999,769 (+)	NCBI	ChiLan1.0	ChiLan1.0

SKP2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	5	36,152,111 - 36,193,530 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	5	36,151,989 - 36,196,849 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	5	36,152,213 - 36,184,421 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	5	36,187,946 - 36,219,904 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	5	36,037,882 - 36,069,833 (+)	NCBI		Celera
Cytogenetic Map	5	p13.2	NCBI
HuRef	5	36,103,294 - 36,135,146 (+)	NCBI		HuRef
CHM1_1	5	36,154,887 - 36,186,889 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	5	36,400,405 - 36,441,818 (+)	NCBI		T2T-CHM13v2.0

Skp2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	15	9,112,070 - 9,155,512 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	15	9,112,073 - 9,155,512 (-)	Ensembl		GRCm39 Ensembl
GRCm38	15	9,111,982 - 9,155,425 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	15	9,111,985 - 9,155,425 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	15	9,041,742 - 9,070,207 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	15	9,038,867 - 9,067,333 (-)	NCBI		MGSCv36	mm8
Celera	15	8,929,103 - 8,957,934 (-)	NCBI		Celera
Cytogenetic Map	15	A1	NCBI
cM Map	15	3.84	NCBI

Skp2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	2	59,888,406 - 59,916,471 (-)	NCBI		GRCr8
mRatBN7.2	2	58,161,226 - 58,189,293 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	2	58,161,229 - 58,189,338 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	2	65,259,097 - 65,287,393 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	2	63,371,360 - 63,399,422 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	2	58,372,679 - 58,400,741 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	2	58,506,146 - 58,534,211 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	2	58,506,151 - 58,534,211 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	2	77,593,574 - 77,621,639 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	2	58,769,164 - 58,797,229 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	2	53,770,002 - 53,798,066 (-)	NCBI		Celera
Cytogenetic Map	2	q16	NCBI

SKP2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	4	74,145,802 - 74,177,662 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	5	72,299,431 - 72,331,350 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	5	74,179,608 - 74,211,563 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	5	79,460,989 - 79,493,000 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	5	79,461,018 - 79,492,311 (-)	Ensembl	panpan1.1		panPan2

SKP2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	4	72,352,966 - 72,386,469 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	4	72,352,986 - 72,386,307 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	4	71,962,697 - 71,996,249 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	4	72,860,285 - 72,892,402 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	4	72,861,375 - 72,892,173 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	4	72,606,024 - 72,639,558 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	4	72,729,654 - 72,763,206 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	4	73,263,074 - 73,296,649 (-)	NCBI		UU_Cfam_GSD_1.0

Skp2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024407213	225,707,776 - 225,735,425 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936518	5,637,331 - 5,664,778 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936518	5,635,856 - 5,664,057 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

SKP2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	16	21,463,012 - 21,509,310 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	16	21,463,270 - 21,500,925 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	16	22,480,017 - 22,517,706 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

SKP2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	4	35,009,114 - 35,040,518 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	4	35,009,076 - 35,042,632 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666071	25,339,782 - 25,375,466 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Skp2
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624759	18,830,323 - 18,858,712 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624759	18,796,055 - 18,858,692 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.


RefSeq Transcripts	XM_005386206	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_005386207	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AGCD01026576	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	GBDF01112275	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSCLAT00000021555 ⟹ ENSCLAP00000021352

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0 Ensembl	NW_004955426	20,972,663 - 20,999,769 (+)	Ensembl

Ensembl Acc Id:

ENSCLAT00000021556 ⟹ ENSCLAP00000021353

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0 Ensembl	NW_004955426	20,972,750 - 20,999,769 (+)	Ensembl

RefSeq Acc Id:

XM_005386206 ⟹ XP_005386263

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0	NW_004955426	20,972,663 - 20,999,769 (+)	NCBI

Sequence:

show sequence

AAAGCGGGAATCCAGGAGGCGGGCAGTTCTGCAATTAATGCACGTATTTAAAACTCCGGACCTGGTGGACGCCATGCACAGGAAGCACCTCCAGGAGATTCCGGACCAGAGTAGCAACGTTACCACCA
GCTTCACATGGGGCTGGGACTCCAGCAAGACCTCTGAGCTGTTGTCAGGCATGGGGGTCTCCGCCCTTGAGAAGGAGGAGGTGGACAGTGAGAACATCCCCCAGGAACTGCTCTCAAACCTGGGCCAC
TCGCAGAGCCCCCCACGGAAAAGGCTGAAGAGCAAAGAAAATGATAAAGATTTTGTGATCATCCGCAGGCCTAGGCTCAATCGAGAGAACTTTCCAGGTGTTTCCTGGGACTCCCTCCCGGATGAGCT
TCTCCTGGGGATCTTTTCCTGTCTGTGCCTCCCCGAGTTGCTGAGAGTCTCCAGTGTCTGTAGGAGATGGTACTGCCTGGCGTTTGATGAGTCTCTTTGGCAGACTCTAGACCTCTCAGGTAGAAATC
TACACCCAGATGTGATTGGTCGCTTGCTGTCTCGAGGCGTGGTTGCCTTCCGCTGCTCACGATCCTTCATGGACCAACCACTGGTTGAACATTTCAGCCCTTTCCGCGTACAGCACATGGACCTGTCA
AACTCTGTTATAAATGTGAATACCCTCCACGGCATTCTGGCTCATTGCGCCAAGCTGCAGAATCTAAGCCTGGAAGGCCTACAGCTTTCAGATCCCATTGTCAATAATCTTGCACAGAACTCAAATTT
AGTGCGACTAAACCTTTGTGGGTGTTCTGGATTTTCGGAATCTGCCCTGAAGACTTTGCTAAGCAGCTGTTCCAGACTGGATGAGCTGAACCTGTCCTGGTGTTTTGATTTCACTGAGAAGCATGTGC
AAGTGGCTGTCACACATGTGTCAGAAACAATCACCCAGCTAAATCTCAGTGGCTATAGGAAGAATCTCCAGAAGTCAGATGTCTGTACCTTAATTAGAAGATGCCCCAACCTTGTCCATCTAGATTTA
AGTGATAGTATCATGCTGAAGAACGACTGCTTTCCAGAATTTTTCCAGCTCAACTACCTCCAACACTTATCACTCAGTCGGTGCTACGATATAATACCTGAAACGCTACTTGAACTTGGAGAAATCCC
TACACTGAAAACACTACAAGTTTTTGGAATCGTGCCAGACGGTACCCTTCAACTGTTAAGGGAAGCCCTTCCTCATCTGCAGATTAATTGCTCCTATTTCACCACCATTGCCAGGCCAACTGTTGGCA
ACAAAAAGAACCAGGAGATATGGGGCATCAAATGCCGCCTGACGCTGCAAAAGCCCAGTTGTCTATGAGGTACTTGCTGCAGGATAGTGTTTTCTCTCCCTTTGGAGTGGGGGAAGCAGGGAGGAAGC
CCAACTGCTGGACACTTGGCTAGTTTTGTTACTGATTTCCCTGTAGCCTTTATCCTGCAAGTATTTTAGGGAAGCATTTAAGAGAAAAAACTATGAGGTGTTGCTTTTTAAAAATGACTTTAAAAGAT
TCTGTCAATGCTGGGCCCTTAAGAGTCTTTGGAGATTTTAGGAGAAGAAGCCTATAATTTCCAGATGACTTTTTAAAGATCAGAACTTGAACCACCTTTCAAGTGCCCTTTTGATTAAGTCTATTTCC
AATCAAGCTTAAAAAATTACCACAGGCTCATAGTCGTCACAGCCTATGTGGTAACTTTTATGCATTTAATTTTCCAGTATTGTTTTTTAAGACACGGCTTATAAGAACATTAAGCTATGTTTGTGCTG
TGAGCTTAACGGTCACAGAATAGTGTTTGAGGTAATCGTTTCTGGGGGTTAGTGCATTTCAGTTTTATCTTTATTTTTAAAATCAGTTTATCGGACAACCCCAAGTAATTCACCATAACCCCTCAATA
AAAAGAAAGAAACAAAGGTGATTGGAGGTTTAAAATTGGTATAGGATTTGAAGGCTCAGGAGGCAATTTTCTATGCCAGGTTAATCTGAAGACTCCTTTAATGTTCATTAATGTACTGTGTTCTCAGA
ATTTCGAATTAGGTAAAGAAATTTTGTGGTTTTCTAACTTTATAATCGAATTATATTATTATGGGTTGTGTAGCTTTTTAAAATGGCTTGCTTTTAGAAAGGATATTATCGTAATCAGTTTATTATTG
AAAAGTTGGATGAAGAATTCTGAACTGATACTGCCTGTTTTCCTTTAGTGCTGACGTTATTTTTATATTACTCTGGAATCAAGTATTTTAAATTGTCTGTTTTAATGGTCTCTCAGAATAACTGTTTG
AAACTACCCACTTTATAAGGTTACTGGACCTACAAACAGCGTATTAAGTCTGAAATGCACTAGAAGCAGGTGTTCCCTGCAGTGCACTTGGCCACTACTTACATCTTATAGAGTTTAGTCACATTGAA
ACTTTTGATGGCACGAGTGATTTTTTTAGAAAACCTAGTACATAGAAGCAAAGAGTTAAATTTTTAAAAAATCACCAAAATATAAATAAATAAACCTAGTTCTAAGTTGATGACGTATTTTCACAACG
CAACAAAAAAGCCAAAACCCATCATCTTTTCTACGAACCACTTAAGTTTACCCCGAGCATCACTCGGGCAGCATATATGTTTACATACCATCCCGAGTTTCACTCGAGCTGTATTGAATACCTATAAA
ATCGTCATTCTTTTATTTCCTGTTACATTATCTTATAAAATTAATGAAAAAATGCAATTTTTGGTCATCCTGTTTATAAATAATT

hide sequence

RefSeq Acc Id:

XM_005386207 ⟹ XP_005386264

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0	NW_004955426	20,972,750 - 20,999,769 (+)	NCBI

Sequence:

show sequence

CGATTGCAAAGAGGTCGGACCGTGGATAGACCTGCTGAATTATTTTAGGCCGCGAATATTGCTACTTGCTAAGATTATTAATGCAGAAGCACCTCCAGGAGATTCCGGACCAGAGTAGCAACGTTACC
ACCAGCTTCACATGGGGCTGGGACTCCAGCAAGACCTCTGAGCTGTTGTCAGGCATGGGGGTCTCCGCCCTTGAGAAGGAGGAGGTGGACAGTGAGAACATCCCCCAGGAACTGCTCTCAAACCTGGG
CCACTCGCAGAGCCCCCCACGGAAAAGGCTGAAGAGCAAAGAAAATGATAAAGATTTTGTGATCATCCGCAGGCCTAGGCTCAATCGAGAGAACTTTCCAGGTGTTTCCTGGGACTCCCTCCCGGATG
AGCTTCTCCTGGGGATCTTTTCCTGTCTGTGCCTCCCCGAGTTGCTGAGAGTCTCCAGTGTCTGTAGGAGATGGTACTGCCTGGCGTTTGATGAGTCTCTTTGGCAGACTCTAGACCTCTCAGGTAGA
AATCTACACCCAGATGTGATTGGTCGCTTGCTGTCTCGAGGCGTGGTTGCCTTCCGCTGCTCACGATCCTTCATGGACCAACCACTGGTTGAACATTTCAGCCCTTTCCGCGTACAGCACATGGACCT
GTCAAACTCTGTTATAAATGTGAATACCCTCCACGGCATTCTGGCTCATTGCGCCAAGCTGCAGAATCTAAGCCTGGAAGGCCTACAGCTTTCAGATCCCATTGTCAATAATCTTGCACAGAACTCAA
ATTTAGTGCGACTAAACCTTTGTGGGTGTTCTGGATTTTCGGAATCTGCCCTGAAGACTTTGCTAAGCAGCTGTTCCAGACTGGATGAGCTGAACCTGTCCTGGTGTTTTGATTTCACTGAGAAGCAT
GTGCAAGTGGCTGTCACACATGTGTCAGAAACAATCACCCAGCTAAATCTCAGTGGCTATAGGAAGAATCTCCAGAAGTCAGATGTCTGTACCTTAATTAGAAGATGCCCCAACCTTGTCCATCTAGA
TTTAAGTGATAGTATCATGCTGAAGAACGACTGCTTTCCAGAATTTTTCCAGCTCAACTACCTCCAACACTTATCACTCAGTCGGTGCTACGATATAATACCTGAAACGCTACTTGAACTTGGAGAAA
TCCCTACACTGAAAACACTACAAGTTTTTGGAATCGTGCCAGACGGTACCCTTCAACTGTTAAGGGAAGCCCTTCCTCATCTGCAGATTAATTGCTCCTATTTCACCACCATTGCCAGGCCAACTGTT
GGCAACAAAAAGAACCAGGAGATATGGGGCATCAAATGCCGCCTGACGCTGCAAAAGCCCAGTTGTCTATGAGGTACTTGCTGCAGGATAGTGTTTTCTCTCCCTTTGGAGTGGGGGAAGCAGGGAGG
AAGCCCAACTGCTGGACACTTGGCTAGTTTTGTTACTGATTTCCCTGTAGCCTTTATCCTGCAAGTATTTTAGGGAAGCATTTAAGAGAAAAAACTATGAGGTGTTGCTTTTTAAAAATGACTTTAAA
AGATTCTGTCAATGCTGGGCCCTTAAGAGTCTTTGGAGATTTTAGGAGAAGAAGCCTATAATTTCCAGATGACTTTTTAAAGATCAGAACTTGAACCACCTTTCAAGTGCCCTTTTGATTAAGTCTAT
TTCCAATCAAGCTTAAAAAATTACCACAGGCTCATAGTCGTCACAGCCTATGTGGTAACTTTTATGCATTTAATTTTCCAGTATTGTTTTTTAAGACACGGCTTATAAGAACATTAAGCTATGTTTGT
GCTGTGAGCTTAACGGTCACAGAATAGTGTTTGAGGTAATCGTTTCTGGGGGTTAGTGCATTTCAGTTTTATCTTTATTTTTAAAATCAGTTTATCGGACAACCCCAAGTAATTCACCATAACCCCTC
AATAAAAAGAAAGAAACAAAGGTGATTGGAGGTTTAAAATTGGTATAGGATTTGAAGGCTCAGGAGGCAATTTTCTATGCCAGGTTAATCTGAAGACTCCTTTAATGTTCATTAATGTACTGTGTTCT
CAGAATTTCGAATTAGGTAAAGAAATTTTGTGGTTTTCTAACTTTATAATCGAATTATATTATTATGGGTTGTGTAGCTTTTTAAAATGGCTTGCTTTTAGAAAGGATATTATCGTAATCAGTTTATT
ATTGAAAAGTTGGATGAAGAATTCTGAACTGATACTGCCTGTTTTCCTTTAGTGCTGACGTTATTTTTATATTACTCTGGAATCAAGTATTTTAAATTGTCTGTTTTAATGGTCTCTCAGAATAACTG
TTTGAAACTACCCACTTTATAAGGTTACTGGACCTACAAACAGCGTATTAAGTCTGAAATGCACTAGAAGCAGGTGTTCCCTGCAGTGCACTTGGCCACTACTTACATCTTATAGAGTTTAGTCACAT
TGAAACTTTTGATGGCACGAGTGATTTTTTTAGAAAACCTAGTACATAGAAGCAAAGAGTTAAATTTTTAAAAAATCACCAAAATATAAATAAATAAACCTAGTTCTAAGTTGATGACGTATTTTCAC
AACGCAACAAAAAAGCCAAAACCCATCATCTTTTCTACGAACCACTTAAGTTTACCCCGAGCATCACTCGGGCAGCATATATGTTTACATACCATCCCGAGTTTCACTCGAGCTGTATTGAATACCTA
TAAAATCGTCATTCTTTTATTTCCTGTTACATTATCTTATAAAATTAATGAAAAAATGCAATTTTTGGTCATCCTGTTTATAAATAATT

hide sequence


Protein RefSeqs	XP_005386263	(Get FASTA)	NCBI Sequence Viewer
	XP_005386264	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCLAP00000021352
	ENSCLAP00000021352.1
	ENSCLAP00000021353
	ENSCLAP00000021353.1

RefSeq Acc Id:	XP_005386263 ⟸ XM_005386206
- Peptide Label:	isoform X1
- UniProtKB:	A0A8C2VW30 (UniProtKB/TrEMBL)
- Sequence:	show sequence MHVFKTPDLVDAMHRKHLQEIPDQSSNVTTSFTWGWDSSKTSELLSGMGVSALEKEEVDSENIPQELLSNLGHSQSPPRKRLKSKENDKDFVIIRRPRLNRENFPGVSWDSLPDELLLGIFSCLCLPE LLRVSSVCRRWYCLAFDESLWQTLDLSGRNLHPDVIGRLLSRGVVAFRCSRSFMDQPLVEHFSPFRVQHMDLSNSVINVNTLHGILAHCAKLQNLSLEGLQLSDPIVNNLAQNSNLVRLNLCGCSGFS ESALKTLLSSCSRLDELNLSWCFDFTEKHVQVAVTHVSETITQLNLSGYRKNLQKSDVCTLIRRCPNLVHLDLSDSIMLKNDCFPEFFQLNYLQHLSLSRCYDIIPETLLELGEIPTLKTLQVFGIVP DGTLQLLREALPHLQINCSYFTTIARPTVGNKKNQEIWGIKCRLTLQKPSCL hide sequence

RefSeq Acc Id:	XP_005386264 ⟸ XM_005386207
- Peptide Label:	isoform X2
- UniProtKB:	A0A8C2VW30 (UniProtKB/TrEMBL)
- Sequence:	show sequence MQKHLQEIPDQSSNVTTSFTWGWDSSKTSELLSGMGVSALEKEEVDSENIPQELLSNLGHSQSP PRKRLKSKENDKDFVIIRRPRLNRENFPGVSWDSLPDELLLGIFSCLCLPELLRVSSVCRRWYCLAFDESLWQTLDLSGRNLHPDVIGRLLSRGVVAFRCSRSFMDQPLVEHFSPFRVQHMDLSNSVI NVNTLHGILAHCAKLQNLSLEGLQLSDPIVNNLAQNSNLVRLNLCGCSGFSESALKTLLSSCSRLDELNLSWCFDFTEKHVQVAVTHVSETITQLNLSGYRKNLQKSDVCTLIRRCPNLVHLDLSDSI MLKNDCFPEFFQLNYLQHLSLSRCYDIIPETLLELGEIPTLKTLQVFGIVPDGTLQLLREALPHLQINCSYFTTIARPTVGNKKNQEIWGIKCRLTLQKPSCL hide sequence

Ensembl Acc Id:

ENSCLAP00000021353 ⟸ ENSCLAT00000021556

Ensembl Acc Id:

ENSCLAP00000021352 ⟸ ENSCLAT00000021555

Protein Domains

F-box

Database	Acc Id	Source(s)
Ensembl Genes	ENSCLAG00000014622	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCLAT00000021555	ENTREZGENE
	ENSCLAT00000021555.1	UniProtKB/TrEMBL
	ENSCLAT00000021556	ENTREZGENE
	ENSCLAT00000021556.1	UniProtKB/TrEMBL
Gene3D-CATH	3.80.10.10	UniProtKB/TrEMBL
InterPro	F-box-like_dom_sf	UniProtKB/TrEMBL
	F-box_dom	UniProtKB/TrEMBL
	Leu-rich_rpt_Cys-con_subtyp	UniProtKB/TrEMBL
	LRR_dom_sf	UniProtKB/TrEMBL
NCBI Gene	Skp2	ENTREZGENE
PANTHER	PROTEIN ARABIDILLO 1	UniProtKB/TrEMBL
	PROTEIN ARABIDILLO 1	UniProtKB/TrEMBL
Pfam	F-box-like	UniProtKB/TrEMBL
PROSITE	FBOX	UniProtKB/TrEMBL
SMART	FBOX	UniProtKB/TrEMBL
	LRR_CC	UniProtKB/TrEMBL
Superfamily-SCOP	RNI-like	UniProtKB/TrEMBL
	SSF81383	UniProtKB/TrEMBL
UniProt	A0A8C2VW30	ENTREZGENE, UniProtKB/TrEMBL
	A0A8C2YT44_CHILA	UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2016-09-20	Skp2	S-phase kinase associated protein 2		S-phase kinase-associated protein 2, E3 ubiquitin protein ligase	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailable


InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailable


Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
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MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Annotations - PID (archival)

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Annotations - PID (archival)