Advanced Search (OLGA)

Gene: SKP2 (S-phase kinase associated protein 2) Sus scrofa

Subscribe to Updates

Analyze

Symbol:

SKP2

Name:

S-phase kinase associated protein 2

RGD ID:

13937049

Description:

ENCODES a protein that exhibits identical protein binding (inferred); kinase activity (inferred); ubiquitin-like ligase-substrate adaptor activity (inferred); INVOLVED IN cellular response to cell-matrix adhesion (ortholog); positive regulation of smooth muscle cell proliferation (ortholog); PARTICIPATES IN Notch signaling pathway; p53 signaling pathway; ASSOCIATED WITH Brain Injuries (ortholog); breast cancer (ortholog); cervix uteri carcinoma in situ (ortholog); FOUND IN cytosol (inferred); nucleolus (inferred); nucleoplasm (inferred); INTERACTS WITH deoxynivalenol

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

S-phase kinase-associated protein 2; S-phase kinase-associated protein 2 (p45)

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

Sscrofa11.1 - Pig Sscrofa11.1 Assembly

Position:

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	16	21,463,012 - 21,509,310 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	16	21,463,270 - 21,500,925 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	16	22,480,017 - 22,517,706 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
SKP2	Pig	Brain Injuries		ISO	RGD:1562456	9068941	protein:increased expression:brain	RGD	PMID:19852587\|REF_RGD_ID:2315049
SKP2	Pig	breast cancer		ISO	RGD:1607086	9068941	protein:increased expression:breast	RGD	PMID:19350629\|REF_RGD_ID:2315035
SKP2	Pig	cervix uteri carcinoma in situ	severity	ISO	RGD:1607086	9068941	associated with Papillomavirus Infections	RGD	PMID:19094580\|REF_RGD_ID:2315036
SKP2	Pig	endometrial hyperplasia		ISO	RGD:1607086	9068941	associated with Endometrial Neoplasms;protein:increased expression:endometrium	RGD	PMID:16080017\|REF_RGD_ID:2315043
SKP2	Pig	Endometrial Neoplasms		ISO	RGD:1607086	9068941		RGD	PMID:15220466\|REF_RGD_ID:2315045
SKP2	Pig	hepatocellular carcinoma		ISO	RGD:1562456	9068941	protein:increased expression:liver	RGD	PMID:19533683\|REF_RGD_ID:2315050
SKP2	Pig	lung small cell carcinoma		ISO	RGD:1607086	9068941	mRNA:increased expression:lung:	RGD	PMID:12107105\|REF_RGD_ID:13825152
SKP2	Pig	Lymphatic Metastasis		ISO	RGD:1607086	9068941	associated with Endometrial Neoplasms;protein:increased expression:endometrium	RGD	PMID:16080017\|REF_RGD_ID:2315043
SKP2	Pig	oral squamous cell carcinoma		ISO	RGD:1607086	9068941	protein:increased expression:mucosa of oral region (human)	RGD	PMID:24743017\|REF_RGD_ID:151665336
SKP2	Pig	Ovarian Neoplasms	disease_progression	ISO	RGD:1607086	9068941		RGD	PMID:16525656\|REF_RGD_ID:2315042
SKP2	Pig	prostate cancer	disease_progression	ISO	RGD:1607086	9068941		RGD	PMID:19450994\|REF_RGD_ID:2315029
SKP2	Pig	prostate carcinoma		ISO	RGD:1607086	9068941		RGD	PMID:12670908\|REF_RGD_ID:2315046
SKP2	Pig	renal cell carcinoma	disease_progression	ISO	RGD:1607086	9068941		RGD	PMID:18922157\|REF_RGD_ID:2315038
SKP2	Pig	transitional cell carcinoma	disease_progression	ISO	RGD:1607086	9068941	protein:increased expression:kidney	RGD	PMID:15351619\|REF_RGD_ID:2315044
SKP2	Pig	Uterine Cervical Neoplasms		ISO	RGD:1607086	9068941	DNA, mRNA:amplification, increased expression:uterine cervix	RGD	PMID:18559093\|REF_RGD_ID:2302384
SKP2	Pig	Uterine Cervical Neoplasms	disease_progression	ISO	RGD:1607086	9068941	associated with Papillomavirus Infections	RGD	PMID:19094580\|REF_RGD_ID:2315036

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
SKP2	Pig	Neurodevelopmental Disorders		ISO	RGD:1607086	8554872	ClinVar Annotator: match by term: Neurodevelopmental disorder	ClinVar	PMID:25741868

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
SKP2	Pig	diffuse large B-cell lymphoma		ISO	RGD:1607086	9068941	CTD Direct Evidence: marker/mechanism	CTD	PMID:18850583
SKP2	Pig	disease of cellular proliferation		ISO	RGD:1607086	9068941	CTD Direct Evidence: marker/mechanism	CTD	PMID:18451165
SKP2	Pig	hepatocellular carcinoma		ISO	RGD:1607086	9068941	CTD Direct Evidence: marker/mechanism	CTD	PMID:12717389
SKP2	Pig	medulloblastoma		ISO	RGD:1607086	9068941	CTD Direct Evidence: marker/mechanism	CTD	PMID:19270706
SKP2	Pig	Ovarian Neoplasms		ISO	RGD:1607086	9068941	CTD Direct Evidence: marker/mechanism	CTD	PMID:19636294
SKP2	Pig	Spine Osteoarthritis		ISO	RGD:1607086	9068941	CTD Direct Evidence: marker/mechanism	CTD	PMID:34697729

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
SKP2	Pig	deoxynivalenol	decreases expression	EXP		6480464	deoxynivalenol results in decreased expression of SKP2 mRNA	CTD	PMID:35307453

Biological Process

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
SKP2	Pig	cellular response to cell-matrix adhesion		ISO	RGD:1562456	9068941		RGD	PMID:11425869\|REF_RGD_ID:2315071
SKP2	Pig	defense response to virus	involved_in	IEA	UniProtKB:Q13309\|ensembl:ENSP00000274255	150520179		Ensembl	GO_REF:0000107
SKP2	Pig	G1/S transition of mitotic cell cycle	acts_upstream_of_or_within	IEA	UniProtKB:Q9Z0Z3\|ensembl:ENSMUSP00000094225	150520179		Ensembl	GO_REF:0000107
SKP2	Pig	G2/M transition of mitotic cell cycle	involved_in	IBA	MGI:1351663\|PANTHER:PTN002700216	150520179		GO_Central	GO_REF:0000033
SKP2	Pig	G2/M transition of mitotic cell cycle	acts_upstream_of_or_within	IEA	UniProtKB:Q9Z0Z3\|ensembl:ENSMUSP00000094225	150520179		Ensembl	GO_REF:0000107
SKP2	Pig	innate immune response	involved_in	IEA	UniProtKB:Q13309\|ensembl:ENSP00000274255	150520179		Ensembl	GO_REF:0000107
SKP2	Pig	positive regulation of double-strand break repair via homologous recombination	involved_in	IEA	UniProtKB:Q13309\|UniProtKB:Q9Z0Z3\|ensembl:ENSMUSP00000094225\|ensembl:ENSP00000274255	150520179		Ensembl	GO_REF:0000107
SKP2	Pig	positive regulation of intracellular estrogen receptor signaling pathway	acts_upstream_of_or_within	IEA	UniProtKB:Q9Z0Z3\|ensembl:ENSMUSP00000094225	150520179		Ensembl	GO_REF:0000107
SKP2	Pig	positive regulation of protein polyubiquitination	acts_upstream_of_or_within	IEA	UniProtKB:Q9Z0Z3\|ensembl:ENSMUSP00000094225	150520179		Ensembl	GO_REF:0000107
SKP2	Pig	positive regulation of smooth muscle cell proliferation		ISO	RGD:1562456	9068941		RGD	PMID:19878790\|REF_RGD_ID:2315048
SKP2	Pig	proteasome-mediated ubiquitin-dependent protein catabolic process	involved_in	IEA	UniProtKB:Q13309\|ensembl:ENSP00000274255	150520179		Ensembl	GO_REF:0000107
SKP2	Pig	protein K48-linked ubiquitination	involved_in	IEA	UniProtKB:Q13309\|ensembl:ENSP00000274255	150520179		Ensembl	GO_REF:0000107
SKP2	Pig	protein K63-linked ubiquitination	involved_in	IEA	UniProtKB:Q13309\|UniProtKB:Q9Z0Z3\|ensembl:ENSMUSP00000094225\|ensembl:ENSP00000274255	150520179		Ensembl	GO_REF:0000107
SKP2	Pig	protein polyubiquitination	acts_upstream_of_or_within	IEA	UniProtKB:Q9Z0Z3\|ensembl:ENSMUSP00000094225	150520179		Ensembl	GO_REF:0000107
SKP2	Pig	regulation of apoptotic process	acts_upstream_of_or_within	IEA	UniProtKB:Q13309\|ensembl:ENSP00000274255	150520179		Ensembl	GO_REF:0000107
SKP2	Pig	regulation of cell cycle	involved_in	IBA	MGI:1351663\|PANTHER:PTN002700216	150520179		GO_Central	GO_REF:0000033
SKP2	Pig	regulation of cell cycle	acts_upstream_of_or_within	IEA	UniProtKB:Q9Z0Z3\|ensembl:ENSMUSP00000094225	150520179		Ensembl	GO_REF:0000107
SKP2	Pig	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process	involved_in	IBA	PANTHER:PTN001923412\|TAIR:locus:2061136\|UniProtKB:Q9UF56	150520179		GO_Central	GO_REF:0000033
SKP2	Pig	ubiquitin-dependent protein catabolic process	acts_upstream_of_or_within	IEA	UniProtKB:Q9Z0Z3\|ensembl:ENSMUSP00000094225	150520179		Ensembl	GO_REF:0000107

Cellular Component

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
SKP2	Pig	cytosol	is_active_in	IBA	PANTHER:PTN002700216\|UniProtKB:Q13309	150520179		GO_Central	GO_REF:0000033
SKP2	Pig	cytosol	located_in	IEA	UniProtKB:Q13309\|ensembl:ENSP00000274255	150520179		Ensembl	GO_REF:0000107
SKP2	Pig	nucleolus	located_in	IEA	UniProtKB:Q13309\|ensembl:ENSP00000274255	150520179		Ensembl	GO_REF:0000107
SKP2	Pig	nucleoplasm	located_in	IEA	UniProtKB:Q13309\|ensembl:ENSP00000274255	150520179		Ensembl	GO_REF:0000107
SKP2	Pig	nucleus	is_active_in	IBA	PANTHER:PTN002700216\|UniProtKB:Q13309	150520179		GO_Central	GO_REF:0000033
SKP2	Pig	SCF ubiquitin ligase complex	part_of	IEA	UniProtKB:Q13309\|UniProtKB:Q9Z0Z3\|ensembl:ENSMUSP00000094225\|ensembl:ENSP00000274255	150520179		Ensembl	GO_REF:0000107
SKP2	Pig	SCF ubiquitin ligase complex	part_of	IBA	FB:FBgn0037236\|MGI:1351663\|PANTHER:PTN001923412\|RGD:1311830\|TAIR:locus:2099237\|TAIR:locus:2125527\|TAIR:locus:2135942\|TAIR:locus:2158824\|UniProtKB:Q13309\|UniProtKB:Q9UF56	150520179		GO_Central	GO_REF:0000033

Molecular Function

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
SKP2	Pig	identical protein binding	enables	IEA	UniProtKB:Q13309\|ensembl:ENSP00000274255	150520179		Ensembl	GO_REF:0000107
SKP2	Pig	kinase activity	enables	IEA	UniProtKB-KW:KW-0418	150520179		UniProt	GO_REF:0000043
SKP2	Pig	protein binding	enables	ISO	PR:P01108	9068941	PMID:23277542	MGI	PMID:23277542
SKP2	Pig	protein binding	enables	ISO	PR:P62878\|PR:Q9WTX5\|PR:Q9WTX6	9068941	PMID:19398581	MGI	PMID:19398581
SKP2	Pig	protein binding	enables	ISO	PR:O35129	9068941	PMID:17785450	MGI	PMID:17785450
SKP2	Pig	protein binding	enables	ISO	UniProtKB:P61024\|UniProtKB:P63208	9068941	PMID:12813041	IntAct	PMID:12813041
SKP2	Pig	protein binding	enables	ISO	UniProtKB:P38936	9068941	PMID:25241761, PMID:30833792	IntAct	PMID:25241761\|PMID:30833792
SKP2	Pig	protein binding	enables	ISO	UniProtKB:P61024\|UniProtKB:Q13616	9068941	PMID:28514442	IntAct	PMID:28514442
SKP2	Pig	protein binding	enables	ISO	UniProtKB:P46527\|UniProtKB:P61024	9068941	PMID:16209941	IntAct	PMID:16209941
SKP2	Pig	protein binding	enables	ISO	UniProtKB:P38936\|UniProtKB:P63208\|UniProtKB:Q4AE16	9068941	PMID:16376880	IntAct	PMID:16376880
SKP2	Pig	protein binding	enables	ISO	UniProtKB:P46527	9068941	PMID:18805092	IntAct	PMID:18805092
SKP2	Pig	protein binding	enables	ISO	UniProtKB:A5D8W4\|UniProtKB:P61024\|UniProtKB:P62877\|UniProtKB:P63208\|UniProtKB:Q13616	9068941	PMID:18239684	IntAct	PMID:18239684
SKP2	Pig	protein binding	enables	ISO	UniProtKB:Q13616	9068941	PMID:12504026, PMID:21145461, PMID:27542266	IntAct	PMID:12504026\|PMID:21145461\|PMID:27542266
SKP2	Pig	protein binding	enables	ISO	UniProtKB:P63208\|UniProtKB:Q13616	9068941	PMID:12609982	IntAct	PMID:12609982
SKP2	Pig	protein binding	enables	ISO	UniProtKB:P09803\|UniProtKB:Q09472\|UniProtKB:Q9NTG7\|UniProtKB:Q9UM11	9068941	PMID:22770219	IntAct	PMID:22770219
SKP2	Pig	protein binding	enables	ISO	UniProtKB:P46527\|UniProtKB:P63208	9068941	PMID:22632967	IntAct	PMID:22632967
SKP2	Pig	protein binding	enables	ISO	UniProtKB:P63208-1	9068941	PMID:11099048, PMID:18667692	IntAct	PMID:11099048\|PMID:18667692
SKP2	Pig	protein binding	enables	ISO	UniProtKB:P35232	9068941	PMID:20134482	IntAct	PMID:20134482
SKP2	Pig	protein binding	enables	ISO	UniProtKB:P28562	9068941	PMID:16286470	IntAct	PMID:16286470
SKP2	Pig	protein binding	enables	ISO	UniProtKB:Q03164	9068941	PMID:20818375	IntAct	PMID:20818375
SKP2	Pig	protein binding	enables	ISO	UniProtKB:P01106	9068941	PMID:17157259	IntAct	PMID:17157259
SKP2	Pig	protein binding	enables	ISO	UniProtKB:P19474	9068941	PMID:16880511	UniProt	PMID:16880511
SKP2	Pig	protein binding		ISO	RGD:1359383	9068941		RGD	PMID:19533683\|REF_RGD_ID:2315050
SKP2	Pig	protein binding		ISO	RGD:727892	9068941		RGD	PMID:19533683\|REF_RGD_ID:2315050
SKP2	Pig	protein binding		ISO	RGD:69328	9068941		RGD	PMID:19533683\|REF_RGD_ID:2315050
SKP2	Pig	protein binding		ISO	RGD:3541	9068941		RGD	PMID:19533683\|REF_RGD_ID:2315050
SKP2	Pig	protein binding	enables	ISO	UniProtKB:Q96Q27	9068941	PMID:21119685	UniProt	PMID:21119685
SKP2	Pig	protein binding	enables	ISO	UniProtKB:Q13415	9068941	PMID:11931757	IntAct	PMID:11931757
SKP2	Pig	protein binding	enables	ISO	UniProtKB:P12004,UniProtKB:Q9H211	9068941	PMID:21856198	CAFA	PMID:21856198
SKP2	Pig	protein binding	enables	ISO	UniProtKB:P27958	9068941	PMID:27194766	UniProt	PMID:27194766
SKP2	Pig	protein binding		ISO	RGD:69062	9068941		RGD	PMID:19852587\|REF_RGD_ID:2315049
SKP2	Pig	protein binding	enables	ISO	UniProtKB:P38936\|UniProtKB:P61024\|UniProtKB:P62877\|UniProtKB:P63208\|UniProtKB:Q9UM11	9068941	PMID:33961781	IntAct	PMID:33961781
SKP2	Pig	protein binding	enables	ISO	UniProtKB:P63208	9068941	PMID:18818696, PMID:23911321, PMID:27705803, PMID:29997244, PMID:31467278, PMID:37398436	IntAct	PMID:18818696\|PMID:23911321\|PMID:27705803\|PMID:29997244\|PMID:31467278\|PMID:37398436
SKP2	Pig	ubiquitin-like ligase-substrate adaptor activity	enables	IEA	UniProtKB:Q13309\|UniProtKB:Q9Z0Z3\|ensembl:ENSMUSP00000094225\|ensembl:ENSP00000274255	150520179		Ensembl	GO_REF:0000107

Imported Annotations - PID (archival)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
SKP2	Pig	Notch signaling pathway		ISO	RGD:1607086	9068941		PID	PID:200015
SKP2	Pig	p53 signaling pathway		ISO	RGD:1607086	9068941		PID	PID:200206

PMID:19322678	PMID:22301074

SKP2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	16	21,463,012 - 21,509,310 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	16	21,463,270 - 21,500,925 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	16	22,480,017 - 22,517,706 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

SKP2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	5	36,152,111 - 36,193,530 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	5	36,151,989 - 36,196,849 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	5	36,152,213 - 36,184,421 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	5	36,187,946 - 36,219,904 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	5	36,037,882 - 36,069,833 (+)	NCBI		Celera
Cytogenetic Map	5	p13.2	NCBI
HuRef	5	36,103,294 - 36,135,146 (+)	NCBI		HuRef
CHM1_1	5	36,154,887 - 36,186,889 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	5	36,400,405 - 36,441,818 (+)	NCBI		T2T-CHM13v2.0

Skp2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	15	9,112,070 - 9,155,512 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	15	9,112,073 - 9,155,512 (-)	Ensembl		GRCm39 Ensembl
GRCm38	15	9,111,982 - 9,155,425 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	15	9,111,985 - 9,155,425 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	15	9,041,742 - 9,070,207 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	15	9,038,867 - 9,067,333 (-)	NCBI		MGSCv36	mm8
Celera	15	8,929,103 - 8,957,934 (-)	NCBI		Celera
Cytogenetic Map	15	A1	NCBI
cM Map	15	3.84	NCBI

Skp2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	2	59,888,406 - 59,916,471 (-)	NCBI		GRCr8
mRatBN7.2	2	58,161,226 - 58,189,293 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	2	58,161,229 - 58,189,338 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	2	65,259,097 - 65,287,393 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	2	63,371,360 - 63,399,422 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	2	58,372,679 - 58,400,741 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	2	58,506,146 - 58,534,211 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	2	58,506,151 - 58,534,211 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	2	77,593,574 - 77,621,639 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	2	58,769,164 - 58,797,229 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	2	53,770,002 - 53,798,066 (-)	NCBI		Celera
Cytogenetic Map	2	q16	NCBI

Skp2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955426	20,972,663 - 20,999,769 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955426	20,972,663 - 20,999,769 (+)	NCBI	ChiLan1.0	ChiLan1.0

SKP2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	4	74,145,802 - 74,177,662 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	5	72,299,431 - 72,331,350 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	5	74,179,608 - 74,211,563 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	5	79,460,989 - 79,493,000 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	5	79,461,018 - 79,492,311 (-)	Ensembl	panpan1.1		panPan2

SKP2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	4	72,352,966 - 72,386,469 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	4	72,352,986 - 72,386,307 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	4	71,962,697 - 71,996,249 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	4	72,860,285 - 72,892,402 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	4	72,861,375 - 72,892,173 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	4	72,606,024 - 72,639,558 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	4	72,729,654 - 72,763,206 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	4	73,263,074 - 73,296,649 (-)	NCBI		UU_Cfam_GSD_1.0

Skp2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024407213	225,707,776 - 225,735,425 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936518	5,637,331 - 5,664,778 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936518	5,635,856 - 5,664,057 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

SKP2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	4	35,009,114 - 35,040,518 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	4	35,009,076 - 35,042,632 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666071	25,339,782 - 25,375,466 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Skp2
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624759	18,830,323 - 18,858,712 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624759	18,796,055 - 18,858,692 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants in SKP2
1584 total Variants

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

alimentary part of gastrointestinal system	circulatory system	ectoderm	endocrine system	endoderm	hemolymphoid system	mesenchyme	mesoderm	nervous system	renal system	reproductive system	respiratory system
10	4	23	3	2	5	14	12	23	3	6	3


RefSeq Transcripts	NM_001171755	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AEMK02000102	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK395880	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CU856110	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FJ536864	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FJ536865	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FJ536866	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	GFLN01061128	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSSSCT00000018330 ⟹ ENSSSCP00000017834

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1 Ensembl	16	21,463,012 - 21,502,542 (+)	Ensembl

Ensembl Acc Id:

ENSSSCT00000067576 ⟹ ENSSSCP00000071639

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1 Ensembl	16	21,463,165 - 21,502,544 (+)	Ensembl

Ensembl Acc Id:

ENSSSCT00000081046 ⟹ ENSSSCP00000061963

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1 Ensembl	16	21,463,697 - 21,502,542 (+)	Ensembl

Ensembl Acc Id:

ENSSSCT00000090589 ⟹ ENSSSCP00000066987

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1 Ensembl	16	21,463,012 - 21,502,542 (+)	Ensembl

Ensembl Acc Id:

ENSSSCT00000097271 ⟹ ENSSSCP00000078707

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1 Ensembl	16	21,463,012 - 21,509,310 (+)	Ensembl

Ensembl Acc Id:

ENSSSCT00000106329 ⟹ ENSSSCP00000080541

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1 Ensembl	16	21,480,055 - 21,502,544 (+)	Ensembl

Ensembl Acc Id:

ENSSSCT00000106493 ⟹ ENSSSCP00000080292

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1 Ensembl	16	21,463,012 - 21,496,206 (+)	Ensembl

RefSeq Acc Id:

NM_001171755 ⟹ NP_001165226

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1	16	21,463,270 - 21,500,925 (+)	NCBI

Sequence:

show sequence

CGGACGCCATGCACAGGAAGCACCTCCAGGAGATTCCCGACCAGAGTAGCAACGTTACCACCAGCTTCACATGGGGATGGGATTCTAGCAAGACTTCTGAACTGCTTTCAGGCATGGGGGTCTCTGCC
TTGGAGAAGGAGGAGGTGGACAGTGAGAACATCCCCCAGGAACTGCTTTCAAACCTGGGCCACCCGCAGAGCCCTCCACGAAAACGGCTGAAGAGCAAAGGGAATGAAAAGGACTTTGTGATCGTCCG
CAGACCTAAGCTAAATCGAGAGAACTTTCCAGGTGTTTCATGGGACTCCCTTCCAGATGAGCTGCTCTTAGGAATCTTTTCCTGTCTATGCCTCCCTGAGCTCCTGAAAGTCTCCAGCGTTTGTAAAA
GATGGTATCATCTAGCGTTTGACGAGTCTCTCTGGCAGACCTTAGACCTCACAGGTAGGAACCTCCACCCAGATGTGACTGGTCGGCTGCTGTCTCGAGGGGTGGTTGCCTTCCGCTGTCCACGATCA
TTTATGGACCAACCGCTAGTCGAACATTTCAGCCCTTTTCGTGTACAGCACATGGACTTGTCAAACTCTGTGATCGATGTGTCTACCCTCCACGGCCTTCTGTCCCAGTGCTCCAAGTTGCAGAATCT
CAGCCTGGAAGGCCTGCGGCTTTCGGATCCCATTGTCAATAATCTTGCTCAGAACACAAATTTAGTGCGACTAAACCTTTCTGGGTGTTCTGGATTCTCCGAATCTGCCCTAAAGACCTTGCTGAGCA
GCTGTTCCAGATTGGATGAGCTGAACCTCTCCTGGTGTTATGACTTCACTGAAAAGCACGTGCAGGTGGCTGTTGCACACGTGTCAGAGACCATCACCCAGCTGAATCTCAGCGGCTACCGAAAGAAT
CTGCAGAAATCAGATGTCTCCACCTTAGTTGGAAGATGTCCCAATCTGGTCCACCTAGATTTAAGTGACAGTGTCATGCTGAAGAATGACTGCTTTCAGGAATTTTACCAGCTCAACTACCTCCAACA
CCTATCCCTCAGTCGATGCTATGACATAATACCCGAAACTTTACTGGAACTTGGAGAAATTCCCACACTAAAAACACTACAAGTCTTTGGAATCGTGCCAGACGGTACCCTTCAACTGTTAAAAGAAG
CCCTTCCTCATCTACAGATTAATTGTTCCCATTTTACCACCATTGCCAGGCCAACCATCGGCAACAAAAAGAACCAGGAGATATGGGGCATCAAATGCCGACTGACACTGCAGAAGCCCAGTTGTCTA
TGAAGTATCTGTTGCAGGATGGTGTCTCCTCTTTTCTTTGAACAGGGAAAGTAGGCAGGAAGCCCAGTTGCTGGAGAACTCAGCTATTTTTATTCTTGGTTTTCCCTTGCCTTCCTTCTCCA

hide sequence


Protein RefSeqs	NP_001165226	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	ACT32454	(Get FASTA)	NCBI Sequence Viewer
	ACT32455	(Get FASTA)	NCBI Sequence Viewer
	ACT32456	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSSSCP00000017834
	ENSSSCP00000017834.3
	ENSSSCP00000061963.1
	ENSSSCP00000066987.2
	ENSSSCP00000071639.2
	ENSSSCP00000078707.1
	ENSSSCP00000080292.1
	ENSSSCP00000080541.1
	ENSSSCP00015036039.1
	ENSSSCP00025009369.1
	ENSSSCP00030028633.1
	ENSSSCP00035035769.1
	ENSSSCP00040034672.1
	ENSSSCP00045006102.1
	ENSSSCP00055003664.1
	ENSSSCP00060043326.1
	ENSSSCP00065016984.1
	ENSSSCP00070012781.1

RefSeq Acc Id:

NP_001165226 ⟸ NM_001171755

- UniProtKB:

D2DGZ0 (UniProtKB/TrEMBL), A0A4X1T9Q5 (UniProtKB/TrEMBL), A0A5G2QBS4 (UniProtKB/TrEMBL), A0A8D0PMB8 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MHRKHLQEIPDQSSNVTTSFTWGWDSSKTSELLSGMGVSALEKEEVDSENIPQELLSNLGHPQSPPRKRLKSKGNEKDFVIVRRPKLNRENFPGVSWDSLPDELLLGIFSCLCLPELLKVSSVCKRWY
HLAFDESLWQTLDLTGRNLHPDVTGRLLSRGVVAFRCPRSFMDQPLVEHFSPFRVQHMDLSNSVIDVSTLHGLLSQCSKLQNLSLEGLRLSDPIVNNLAQNTNLVRLNLSGCSGFSESALKTLLSSCS
RLDELNLSWCYDFTEKHVQVAVAHVSETITQLNLSGYRKNLQKSDVSTLVGRCPNLVHLDLSDSVMLKNDCFQEFYQLNYLQHLSLSRCYDIIPETLLELGEIPTLKTLQVFGIVPDGTLQLLKEALP
HLQINCSHFTTIARPTIGNKKNQEIWGIKCRLTLQKPSCL

hide sequence

Ensembl Acc Id:

ENSSSCP00000066987 ⟸ ENSSSCT00000090589

Ensembl Acc Id:

ENSSSCP00000061963 ⟸ ENSSSCT00000081046

Ensembl Acc Id:

ENSSSCP00000017834 ⟸ ENSSSCT00000018330

Ensembl Acc Id:

ENSSSCP00000071639 ⟸ ENSSSCT00000067576

Protein Domains

F-box

Database	Acc Id	Source(s)
Ensembl Genes	ENSSSCG00000016835	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
	ENSSSCG00015064880	UniProtKB/TrEMBL
	ENSSSCG00025016607	UniProtKB/TrEMBL
	ENSSSCG00030044758	UniProtKB/TrEMBL
	ENSSSCG00035063834	UniProtKB/TrEMBL
	ENSSSCG00040058520	UniProtKB/TrEMBL
	ENSSSCG00045005385	UniProtKB/TrEMBL
	ENSSSCG00055002432	UniProtKB/TrEMBL
	ENSSSCG00060072587	UniProtKB/TrEMBL
	ENSSSCG00065029758	UniProtKB/TrEMBL
	ENSSSCG00070007944	UniProtKB/TrEMBL
Ensembl Transcript	ENSSSCT00000018330	ENTREZGENE
	ENSSSCT00000018330.5	UniProtKB/TrEMBL
	ENSSSCT00000067576.2	UniProtKB/TrEMBL
	ENSSSCT00000081046.2	UniProtKB/TrEMBL
	ENSSSCT00000090589.2	UniProtKB/TrEMBL
	ENSSSCT00000097271.1	UniProtKB/TrEMBL
	ENSSSCT00000106329.1	UniProtKB/TrEMBL
	ENSSSCT00000106493.1	UniProtKB/TrEMBL
	ENSSSCT00015088391.1	UniProtKB/TrEMBL
	ENSSSCT00025022616.1	UniProtKB/TrEMBL
	ENSSSCT00030062622.1	UniProtKB/TrEMBL
	ENSSSCT00035085942.1	UniProtKB/TrEMBL
	ENSSSCT00040080130.1	UniProtKB/TrEMBL
	ENSSSCT00045008977.1	UniProtKB/TrEMBL
	ENSSSCT00055004737.1	UniProtKB/TrEMBL
	ENSSSCT00060099868.1	UniProtKB/TrEMBL
	ENSSSCT00065040192.1	UniProtKB/TrEMBL
	ENSSSCT00070015456.1	UniProtKB/TrEMBL
Gene3D-CATH	3.80.10.10	UniProtKB/TrEMBL
InterPro	F-box-like_dom_sf	UniProtKB/TrEMBL
	F-box_dom	UniProtKB/TrEMBL
	Leu-rich_rpt_Cys-con_subtyp	UniProtKB/TrEMBL
	LRR_dom_sf	UniProtKB/TrEMBL
KEGG Report	ssc:100329128	UniProtKB/TrEMBL
NCBI Gene	SKP2	ENTREZGENE
PANTHER	F-BOX PROTEIN YLR352W	UniProtKB/TrEMBL
	PARTNER OF PAIRED, ISOFORM B-RELATED	UniProtKB/TrEMBL
	PROTEIN ARABIDILLO 1	UniProtKB/TrEMBL
	PROTEIN ARABIDILLO 1	UniProtKB/TrEMBL
Pfam	F-box-like	UniProtKB/TrEMBL
PROSITE	FBOX	UniProtKB/TrEMBL
SMART	FBOX	UniProtKB/TrEMBL
	LRR_CC	UniProtKB/TrEMBL
Superfamily-SCOP	RNI-like	UniProtKB/TrEMBL
	SSF81383	UniProtKB/TrEMBL
UniProt	A0A4X1T9Q5	ENTREZGENE, UniProtKB/TrEMBL
	A0A5G2QBS4	ENTREZGENE
	A0A5G2QQI0_PIG	UniProtKB/TrEMBL
	A0A5G2RIX7_PIG	UniProtKB/TrEMBL
	A0A8D0PMB8	ENTREZGENE, UniProtKB/TrEMBL
	A0A8W4FHJ2_PIG	UniProtKB/TrEMBL
	A0A8W4FM66_PIG	UniProtKB/TrEMBL
	A0A8W4FMG5_PIG	UniProtKB/TrEMBL
	D2DGZ0	ENTREZGENE, UniProtKB/TrEMBL
	D2DGZ1_PIG	UniProtKB/TrEMBL
	D2DGZ2_PIG	UniProtKB/TrEMBL
	F6Q6U7_PIG	UniProtKB/TrEMBL
UniProt Secondary	A0A5G2QBS4	UniProtKB/TrEMBL
	A0A8D1FD99	UniProtKB/TrEMBL
VGNC ID	VGNC:92907	ENTREZGENE

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailable


InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailable


Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
		Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Annotations - PID (archival)

Send us a Message

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Annotations - PID (archival)