Symbol:
TNP2
Name:
transition protein 2
RGD ID:
736031
HGNC Page
HGNC:11952
Description:
Predicted to enable zinc ion binding activity. Predicted to be involved in several processes, including penetration of zona pellucida; positive regulation of protein processing; and sperm DNA condensation. Predicted to act upstream of or within binding activity of sperm to zona pellucida and flagellated sperm motility. Predicted to be located in male germ cell nucleus. Predicted to be part of nucleosome. Predicted to be active in nucleus.
Type:
protein-coding
RefSeq Status:
VALIDATED
Previously known as:
MGC116783; MGC116785; nuclear transition protein 2; TP-2; TP2; transition protein 2 (during histone to protamine replacement)
RGD Orthologs
Alliance Orthologs
More Info
more info ...
More Info
Species
Gene symbol and name
Data Source
Assertion derived from
less info ...
Orthologs 1
Mus musculus (house mouse):
Tnp2 (transition protein 2) HGNC
Ensembl, HGNC, Inparanoid, NCBI, OMA, OrthoMCL, Panther
Rattus norvegicus (Norway rat):
Tnp2 (transition protein 2) HGNC
Ensembl, Inparanoid, NCBI, OMA, OrthoMCL, Panther
Chinchilla lanigera (long-tailed chinchilla):
Tnp2 (transition protein 2) NCBI
Ortholog
Pan paniscus (bonobo/pygmy chimpanzee):
TNP2 (transition protein 2) NCBI
Ortholog
Canis lupus familiaris (dog):
TNP2 (transition protein 2) HGNC
HomoloGene, NCBI
Sus scrofa (pig):
TNP2 (transition protein 2) HGNC
EggNOG, Ensembl, Inparanoid, NCBI, OMA, OrthoDB, Panther, Treefam
Chlorocebus sabaeus (green monkey):
TNP2 (transition protein 2) NCBI
Ortholog
Heterocephalus glaber (naked mole-rat):
Tnp2 (transition protein 2) NCBI
Ortholog
Alliance orthologs 3
Rattus norvegicus (Norway rat):
Tnp2 (transition protein 2)
Alliance
DIOPT (Ensembl Compara|HGNC|Hieranoid|InParanoid|OMA|OrthoFinder|PANTHER|PhylomeDB)
Mus musculus (house mouse):
Tnp2 (transition protein 2)
Alliance
DIOPT (Ensembl Compara|HGNC|Hieranoid|InParanoid|OMA|OrthoFinder|PANTHER|PhylomeDB)
Allele / Splice:
See ClinVar data
Latest Assembly:
GRCh38 - Human Genome Assembly GRCh38
Position:
Human Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCh38 16 11,267,857 - 11,269,325 (-) NCBI GRCh38 GRCh38 hg38 GRCh38 GRCh38.p14 Ensembl 16 11,267,748 - 11,269,533 (-) Ensembl GRCh38 hg38 GRCh38 GRCh37 16 11,361,714 - 11,363,182 (-) NCBI GRCh37 GRCh37 hg19 GRCh37 Build 36 16 11,269,215 - 11,270,661 (-) NCBI NCBI36 Build 36 hg18 NCBI36 Build 34 16 11,269,214 - 11,270,661 NCBI Celera 16 11,531,105 - 11,532,551 (-) NCBI Celera Cytogenetic Map 16 p13.13 NCBI HuRef 16 11,279,446 - 11,280,892 (-) NCBI HuRef CHM1_1 16 11,361,620 - 11,363,066 (-) NCBI CHM1_1 T2T-CHM13v2.0 16 11,304,079 - 11,305,547 (-) NCBI T2T-CHM13v2.0
JBrowse:
View Region in Genome Browser (JBrowse)
Model
TNP2 Human Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCh38 16 11,267,857 - 11,269,325 (-) NCBI GRCh38 GRCh38 hg38 GRCh38 GRCh38.p14 Ensembl 16 11,267,748 - 11,269,533 (-) Ensembl GRCh38 hg38 GRCh38 GRCh37 16 11,361,714 - 11,363,182 (-) NCBI GRCh37 GRCh37 hg19 GRCh37 Build 36 16 11,269,215 - 11,270,661 (-) NCBI NCBI36 Build 36 hg18 NCBI36 Build 34 16 11,269,214 - 11,270,661 NCBI Celera 16 11,531,105 - 11,532,551 (-) NCBI Celera Cytogenetic Map 16 p13.13 NCBI HuRef 16 11,279,446 - 11,280,892 (-) NCBI HuRef CHM1_1 16 11,361,620 - 11,363,066 (-) NCBI CHM1_1 T2T-CHM13v2.0 16 11,304,079 - 11,305,547 (-) NCBI T2T-CHM13v2.0
Tnp2 Mouse Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCm39 16 10,605,799 - 10,606,519 (-) NCBI GRCm39 GRCm39 mm39 GRCm39 Ensembl 16 10,605,800 - 10,606,524 (-) Ensembl GRCm39 Ensembl GRCm38 16 10,787,935 - 10,788,655 (-) NCBI GRCm38 GRCm38 mm10 GRCm38 GRCm38.p6 Ensembl 16 10,787,936 - 10,788,660 (-) Ensembl GRCm38 mm10 GRCm38 MGSCv37 16 10,788,028 - 10,788,748 (-) NCBI GRCm37 MGSCv37 mm9 NCBIm37 MGSCv36 16 10,701,513 - 10,702,233 (-) NCBI MGSCv36 mm8 Celera 16 11,415,373 - 11,416,093 (-) NCBI Celera Cytogenetic Map 16 A1 NCBI cM Map 16 5.83 NCBI
Tnp2 Rat Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCr8 10 5,386,735 - 5,387,463 (+) NCBI GRCr8 mRatBN7.2 10 4,879,812 - 4,880,540 (+) NCBI mRatBN7.2 mRatBN7.2 mRatBN7.2 Ensembl 10 4,879,812 - 4,880,538 (+) Ensembl mRatBN7.2 Ensembl UTH_Rnor_SHR_Utx 10 9,576,387 - 9,577,115 (+) NCBI Rnor_SHR UTH_Rnor_SHR_Utx UTH_Rnor_SHRSP_BbbUtx_1.0 10 9,097,503 - 9,098,231 (+) NCBI Rnor_SHRSP UTH_Rnor_SHRSP_BbbUtx_1.0 UTH_Rnor_WKY_Bbb_1.0 10 4,735,784 - 4,736,512 (+) NCBI Rnor_WKY UTH_Rnor_WKY_Bbb_1.0 Rnor_6.0 10 4,953,898 - 4,954,626 (+) NCBI Rnor6.0 Rnor_6.0 rn6 Rnor6.0 Rnor_6.0 Ensembl 10 4,953,879 - 4,954,624 (+) Ensembl Rnor6.0 rn6 Rnor6.0 Rnor_5.0 10 3,780,384 - 3,781,112 (+) NCBI Rnor5.0 Rnor_5.0 rn5 Rnor5.0 RGSC_v3.4 10 4,816,612 - 4,817,340 (+) NCBI RGSC3.4 RGSC_v3.4 rn4 RGSC3.4 RGSC_v3.1 10 4,816,611 - 4,817,338 (+) NCBI Celera 10 3,901,408 - 3,902,136 (+) NCBI Celera Cytogenetic Map 10 q11 NCBI
Tnp2 Chinchilla Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl ChiLan1.0 NW_004955442 7,311,826 - 7,314,046 (+) NCBI ChiLan1.0 ChiLan1.0
TNP2 Bonobo Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl NHGRI_mPanPan1-v2 18 11,817,009 - 11,819,356 (-) NCBI NHGRI_mPanPan1-v2 NHGRI_mPanPan1 16 15,587,457 - 15,589,800 (-) NCBI NHGRI_mPanPan1 Mhudiblu_PPA_v0 16 10,209,801 - 10,211,466 (-) NCBI Mhudiblu_PPA_v0 Mhudiblu_PPA_v0 panPan3 PanPan1.1 16 11,431,694 - 11,433,158 (-) NCBI panpan1.1 PanPan1.1 panPan2 PanPan1.1 Ensembl 16 11,431,822 - 11,433,087 (-) Ensembl panpan1.1 panPan2
TNP2 Dog Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl CanFam3.1 6 31,498,361 - 31,498,740 (+) NCBI CanFam3.1 CanFam3.1 canFam3 CanFam3.1 CanFam3.1 Ensembl 6 31,426,715 - 31,499,842 (+) Ensembl CanFam3.1 canFam3 CanFam3.1 Dog10K_Boxer_Tasha 6 32,881,238 - 32,881,617 (+) NCBI Dog10K_Boxer_Tasha ROS_Cfam_1.0 6 31,680,942 - 31,682,492 (+) NCBI ROS_Cfam_1.0 UMICH_Zoey_3.1 6 31,494,292 - 31,494,671 (+) NCBI UMICH_Zoey_3.1 UNSW_CanFamBas_1.0 6 31,368,582 - 31,368,961 (+) NCBI UNSW_CanFamBas_1.0 UU_Cfam_GSD_1.0 6 31,792,757 - 31,794,307 (+) NCBI UU_Cfam_GSD_1.0
TNP2 Pig Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl Sscrofa11.1 Ensembl 3 31,870,068 - 31,871,702 (+) Ensembl Sscrofa11.1 susScr11 Sscrofa11.1 Sscrofa11.1 3 31,868,517 - 31,871,530 (+) NCBI Sscrofa11.1 Sscrofa11.1 susScr11 Sscrofa11.1 Sscrofa10.2 3 32,659,663 - 32,661,176 (+) NCBI Sscrofa10.2 Sscrofa10.2 susScr3 Pig Cytomap 3 p13-cent NCBI
TNP2 Green Monkey Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl ChlSab1.1 5 10,744,762 - 10,746,244 (-) NCBI ChlSab1.1 ChlSab1.1 chlSab2 ChlSab1.1 Ensembl 5 10,744,915 - 10,746,159 (-) Ensembl ChlSab1.1 ChlSab1.1 Ensembl chlSab2 Vero_WHO_p1.0 NW_023666068 19,417,005 - 19,418,243 (+) NCBI Vero_WHO_p1.0 Vero_WHO_p1.0
Tnp2
.
Predicted Target Of
Count of predictions: 249 Count of miRNA genes: 232 Interacting mature miRNAs: 240 Transcripts: ENST00000312693, ENST00000560751 Prediction methods: Miranda, Rnahybrid, Targetscan Result types: miRGate_prediction
RH70860
Human Assembly Chr Position (strand) Source JBrowse GRCh37 16 11,361,741 - 11,361,867 UniSTS GRCh37 Build 36 16 11,269,242 - 11,269,368 RGD NCBI36 Celera 16 11,531,132 - 11,531,258 RGD Cytogenetic Map 16 p13.13 UniSTS HuRef 16 11,279,473 - 11,279,599 UniSTS GeneMap99-GB4 RH Map 16 98.95 UniSTS
UniSTS:482873
Human Assembly Chr Position (strand) Source JBrowse GRCh37 16 11,361,822 - 11,363,138 UniSTS GRCh37 Celera 16 11,531,213 - 11,532,529 UniSTS HuRef 16 11,279,554 - 11,280,870 UniSTS
Click on a value in the shaded box below the category label to view a detailed expression data table for that system.
alimentary part of gastrointestinal system
124
262
212
160
931
367
290
51
279
37
187
691
676
825
83
726
205
14
Too many to show, limit is 500. Download them if you would like to view them all.
Ensembl Acc Id:
ENST00000312693 ⟹ ENSP00000325738
Type:
CODING
Position:
Human Assembly Chr Position (strand) Source GRCh38.p14 Ensembl 16 11,267,857 - 11,269,325 (-) Ensembl
Ensembl Acc Id:
ENST00000560751 ⟹ ENSP00000496261
Type:
CODING
Position:
Human Assembly Chr Position (strand) Source GRCh38.p14 Ensembl 16 11,267,748 - 11,269,533 (-) Ensembl
RefSeq Acc Id:
NM_005425 ⟹ NP_005416
RefSeq Status:
VALIDATED
Type:
CODING
Position:
Human Assembly Chr Position (strand) Source GRCh38 16 11,267,857 - 11,269,325 (-) NCBI GRCh37 16 11,361,714 - 11,363,160 (-) ENTREZGENE Build 36 16 11,269,215 - 11,270,661 (-) NCBI Archive HuRef 16 11,279,446 - 11,280,892 (-) ENTREZGENE CHM1_1 16 11,361,620 - 11,363,066 (-) NCBI T2T-CHM13v2.0 16 11,304,079 - 11,305,547 (-) NCBI
Sequence:
GTAAAGCTAGGCCTGCTGGGAGAGGATGAGGAGGAGGCCCTGCCCCTCCAAACGTGGCCTCCTATGGACACCCAGACTCACAGCCTTCCTATCACCCACACTCAGCTCCATAGCAACTCTCAGCCCCA
hide sequence
RefSeq Acc Id:
NP_005416 ⟸ NM_005425
- UniProtKB:
Q9NZB0 (UniProtKB/Swiss-Prot), Q05952 (UniProtKB/Swiss-Prot), Q4VB56 (UniProtKB/TrEMBL), A0A2R8Y7P0 (UniProtKB/TrEMBL)
- Sequence:
MDTQTHSLPITHTQLHSNSQPQSRTCTRHCQTFSQSCRQSHRGSRSQSSSQSPASHRNPTGAHSSSGHQSQSPNTSPPPKRHKKTMNSHHSPMRPTILHCRCPKNRKNLEGKLKKKKMAKRIQQVYKT
hide sequence
Ensembl Acc Id:
ENSP00000496261 ⟸ ENST00000560751
Ensembl Acc Id:
ENSP00000325738 ⟸ ENST00000312693
RGD ID: 7231331 Promoter ID: EPDNEW_H21411 Type: single initiation site Name: TNP2_1 Description: transition protein 2 SO ACC ID: SO:0000170 Source: EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/ ) Experiment Methods: Single-end sequencing. Position: Human Assembly Chr Position (strand) Source GRCh38 16 11,269,325 - 11,269,385 EPDNEW
Date
Current Symbol
Current Name
Previous Symbol
Previous Name
Description
Reference
Status
2016-07-26
TNP2
transition protein 2
transition protein 2 (during histone to protamine replacement)
Symbol and/or name change
5135510 APPROVED
