TNP2 (transition protein 2) - Rat Genome Database

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Gene: TNP2 (transition protein 2) Chlorocebus sabaeus
Analyze
Symbol: TNP2
Name: transition protein 2
RGD ID: 18535592
Description: ENCODES a protein that exhibits zinc ion binding (ortholog); INVOLVED IN acrosome reaction (ortholog); binding of sperm to zona pellucida (ortholog); flagellated sperm motility (ortholog); ASSOCIATED WITH Charcot-Marie-Tooth disease type 1C (ortholog); Landau-Kleffner syndrome (ortholog); MHC class II deficiency (ortholog); FOUND IN male germ cell nucleus (ortholog); nucleus (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: nuclear transition protein 2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1510,744,762 - 10,746,244 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl510,744,915 - 10,746,159 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606819,417,005 - 19,418,243 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
TNP2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1510,744,762 - 10,746,244 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl510,744,915 - 10,746,159 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606819,417,005 - 19,418,243 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
TNP2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381611,267,857 - 11,269,325 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1611,267,748 - 11,269,533 (-)EnsemblGRCh38hg38GRCh38
GRCh371611,361,714 - 11,363,182 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361611,269,215 - 11,270,661 (-)NCBINCBI36Build 36hg18NCBI36
Build 341611,269,214 - 11,270,661NCBI
Celera1611,531,105 - 11,532,551 (-)NCBICelera
Cytogenetic Map16p13.13NCBI
HuRef1611,279,446 - 11,280,892 (-)NCBIHuRef
CHM1_11611,361,620 - 11,363,066 (-)NCBICHM1_1
T2T-CHM13v2.01611,304,079 - 11,305,547 (-)NCBIT2T-CHM13v2.0
Tnp2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391610,605,799 - 10,606,519 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1610,605,800 - 10,606,524 (-)EnsemblGRCm39 Ensembl
GRCm381610,787,935 - 10,788,655 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1610,787,936 - 10,788,660 (-)EnsemblGRCm38mm10GRCm38
MGSCv371610,788,028 - 10,788,748 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361610,701,513 - 10,702,233 (-)NCBIMGSCv36mm8
Celera1611,415,373 - 11,416,093 (-)NCBICelera
Cytogenetic Map16A1NCBI
cM Map165.83NCBI
Tnp2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8105,386,735 - 5,387,463 (+)NCBIGRCr8
mRatBN7.2104,879,812 - 4,880,540 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl104,879,812 - 4,880,538 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx109,576,387 - 9,577,115 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0109,097,503 - 9,098,231 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0104,735,784 - 4,736,512 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0104,953,898 - 4,954,626 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl104,953,879 - 4,954,624 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0103,780,384 - 3,781,112 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4104,816,612 - 4,817,340 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1104,816,611 - 4,817,338 (+)NCBI
Celera103,901,408 - 3,902,136 (+)NCBICelera
Cytogenetic Map10q11NCBI
Tnp2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049554427,311,826 - 7,314,046 (+)NCBIChiLan1.0ChiLan1.0
TNP2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21811,817,009 - 11,819,356 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11615,587,457 - 15,589,800 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01610,209,801 - 10,211,466 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11611,431,694 - 11,433,158 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1611,431,822 - 11,433,087 (-)Ensemblpanpan1.1panPan2
TNP2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1631,498,361 - 31,498,740 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl631,426,715 - 31,499,842 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha632,881,238 - 32,881,617 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0631,680,942 - 31,682,492 (+)NCBIROS_Cfam_1.0
UMICH_Zoey_3.1631,494,292 - 31,494,671 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0631,368,582 - 31,368,961 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0631,792,757 - 31,794,307 (+)NCBIUU_Cfam_GSD_1.0
TNP2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl331,870,068 - 31,871,702 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1331,868,517 - 31,871,530 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2332,659,663 - 32,661,176 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Pig Cytomap3p13-centNCBI
Tnp2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248248,453,667 - 8,454,987 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in TNP2
27 total Variants

Expression

RNA-SEQ Expression

ectoderm
endocrine system
hemolymphoid system
mesenchyme
mesoderm
nervous system
reproductive system
36 6 18 18 18 36 6

Sequence


Ensembl Acc Id: ENSCSAT00000006442   ⟹   ENSCSAP00000004646
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl510,744,915 - 10,746,159 (-)Ensembl
RefSeq Acc Id: XM_037989854   ⟹   XP_037845782
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366606819,417,005 - 19,418,243 (+)NCBI
Protein Sequences
Protein RefSeqs XP_037845782 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000004646.1
Ensembl Acc Id: ENSCSAP00000004646   ⟸   ENSCSAT00000006442
RefSeq Acc Id: XP_037845782   ⟸   XM_037989854


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000008391 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000006442.1 UniProtKB/TrEMBL
InterPro TP2 UniProtKB/TrEMBL
KEGG Report csab:103228304 UniProtKB/TrEMBL
NCBI Gene TNP2 ENTREZGENE
PANTHER NUCLEAR TRANSITION PROTEIN 2 UniProtKB/TrEMBL
  PTHR17488 UniProtKB/TrEMBL
Pfam TP2 UniProtKB/TrEMBL
PROSITE TP2_1 UniProtKB/TrEMBL
  TP2_2 UniProtKB/TrEMBL
UniProt A0A0D9R7Q7_CHLSB UniProtKB/TrEMBL