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Gene: Pth1r (parathyroid hormone 1 receptor) Mus musculus
Symbol: Pth1r
Name: parathyroid hormone 1 receptor
RGD ID: 731313
Description: Exhibits parathyroid hormone receptor activity. Involved in several processes, including G protein-coupled receptor signaling pathway; bone resorption; and osteoblast development. Localizes to intracellular. Is expressed in several structures, including extraembryonic component; integumental system; limb; lung; and skeleton. Human ortholog(s) of this gene implicated in Eiken syndrome; Jansen's metaphyseal chondrodysplasia; chondrodysplasia Blomstrand type; osteochondrodysplasia; and primary failure of tooth eruption. Orthologous to human PTH1R (parathyroid hormone 1 receptor); PARTICIPATES IN G protein mediated signaling pathway via Galphaq family; G protein mediated signaling pathway via Galphas family; parathyroid hormone signaling pathway; INTERACTS WITH 1,1-dichloroethene; 1,2-dimethylhydrazine; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: parathyroid hormone receptor 1; parathyroid hormone/parathyroid hormone-related peptide receptor; PPR; PTH; PTH-related peptide receptor; PTH/PTHr receptor; PTH/PTHrP receptor; PTH/PTHrP type I receptor; PTH1 receptor; Pthr; Pthr1
Homo sapiens (human) : PTH1R (parathyroid hormone 1 receptor)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Pth1r (parathyroid hormone 1 receptor)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pth1r (parathyroid hormone 1 receptor)
Pan paniscus (bonobo/pygmy chimpanzee) : PTH1R (parathyroid hormone 1 receptor)
Canis lupus familiaris (dog) : PTH1R (parathyroid hormone 1 receptor)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pth1r (parathyroid hormone 1 receptor)
Sus scrofa (pig) : PTH1R (parathyroid hormone 1 receptor)
Chlorocebus sabaeus (African green monkey) : PTH1R (parathyroid hormone 1 receptor)
Heterocephalus glaber (naked mole-rat) : Pth1r (parathyroid hormone 1 receptor)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm399110,551,132 - 110,576,213 (-)NCBI
GRCm389110,722,085 - 110,747,145 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl9110,722,085 - 110,747,145 (-)EnsemblGRCm38mm10GRCm38
MGSCv379110,624,589 - 110,649,649 (-)NCBIGRCm37mm9NCBIm37
MGSCv369110,567,070 - 110,587,116 (-)NCBImm8
Celera9110,451,883 - 110,476,939 (-)NCBICelera
Cytogenetic Map9F2NCBI
cM Map960.56NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Pth1r
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 731313
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2020-10-13
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.