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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 731313
Species: Mus musculus
RGD Object: Gene
Symbol: Pth1r
Name: parathyroid hormone 1 receptor
Acc ID: CHEBI:16469
Term: 17beta-estradiol
Definition: The 17beta-isomer of estradiol.
Chemical ID: MESH:D004958
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Pth1raffects expressionISOPth1r (Rattus norvegicus)6480464CTDEstradiol affects the expression of PTH1R mRNAPMID:12810170
Pth1rincreases expressionISOPth1r (Rattus norvegicus)6480464CTDEstradiol results in increased expression of PTH1R mRNAPMID:32145629
Pth1rincreases expressionISOPTH1R (Homo sapiens)6480464CTDEstradiol results in increased expression of PTH1R mRNAPMID:31614463
Pth1rmultiple interactionsISOPTH1R (Homo sapiens)6480464CTD[Estradiol binds to ESR2 protein] which results in increased expression of PTH1R mRNAPMID:20404318
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