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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 731313
Species: Mus musculus
RGD Object: Gene
Symbol: Pth1r
Name: parathyroid hormone 1 receptor
Acc ID: CHEBI:28119
Term: 2,3,7,8-tetrachlorodibenzodioxine
Definition: A polychlorinated dibenzodioxine that has formula C12H4Cl4O2.
Chemical ID: MESH:D013749
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Pth1rdecreases expressionEXP 6480464CTDTetrachlorodibenzodioxin results in decreased expression of PTH1R mRNAPMID:26290441
Pth1rdecreases expressionISOPth1r (Rattus norvegicus)6480464CTDTetrachlorodibenzodioxin results in decreased expression of PTH1R mRNAPMID:19490992 PMID:22808131 PMID:32109520 PMID:34747641
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