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Gene: Tgfbr3 (transforming growth factor, beta receptor III) Mus musculus
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Symbol: Tgfbr3
Name: transforming growth factor, beta receptor III
Description: Exhibits several functions, including PDZ domain binding activity; transforming growth factor beta binding activity; and transforming growth factor beta-activated receptor activity. Involved in several processes, including heart development; positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway; and transmembrane receptor protein serine/threonine kinase signaling pathway. Localizes to cell surface and endoplasmic reticulum. Is expressed in several structures, including brain; early conceptus; heart; lower jaw; and ovary. Orthologous to human TGFBR3 (transforming growth factor beta receptor 3); PARTICIPATES IN transforming growth factor-beta Smad dependent signaling pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3,4-methylenedioxymethamphetamine; 4,4'-sulfonyldiphenol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 1110036H20Rik; AU015626; AW215636; betagl; betaglycan; TB; TBRIII; TGF-beta receptor type 3; TGF-beta receptor type III; TGFR-3; transforming growth factor beta receptor III; transforming growth factor beta receptor type 3
Orthologs:
Homo sapiens (human) : TGFBR3 (transforming growth factor beta receptor 3)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Tgfbr3 (transforming growth factor beta receptor 3)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tgfbr3 (transforming growth factor beta receptor 3)
Pan paniscus (bonobo/pygmy chimpanzee) : TGFBR3 (transforming growth factor beta receptor 3)
Canis lupus familiaris (dog) : TGFBR3 (transforming growth factor beta receptor 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tgfbr3 (transforming growth factor beta receptor 3)
Sus scrofa (pig) : TGFBR3 (transforming growth factor beta receptor 3)
Chlorocebus sabaeus (African green monkey) : TGFBR3 (transforming growth factor beta receptor 3)
Heterocephalus glaber (naked mole-rat) : Tgfbr3 (transforming growth factor beta receptor 3)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38.p6 Ensembl5107,106,570 - 107,289,629 (-)EnsemblGRCm38mm10GRCm38
GRCm385107,106,567 - 107,289,629 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv375107,535,589 - 107,718,614 (-)NCBIGRCm37mm9NCBIm37
MGSCv365107,346,872 - 107,529,822 (-)NCBImm8
Celera5104,218,970 - 104,402,013 (-)NCBICelera
Cytogenetic Map5E5NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
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References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
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Additional Information

External Database Links
 
More on Tgfbr3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 62112
Created: 2001-04-11
Species: Mus musculus
Last Modified: 2020-09-09
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.