Tgfbr3 (transforming growth factor beta receptor 3) - Rat Genome Database

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Gene: Tgfbr3 (transforming growth factor beta receptor 3) Ictidomys tridecemlineatus
Analyze
Symbol: Tgfbr3
Name: transforming growth factor beta receptor 3
RGD ID: 12621976
Description: ENCODES a protein that exhibits activin binding (ortholog); coreceptor activity (ortholog); fibroblast growth factor binding (ortholog); INVOLVED IN animal organ regeneration (ortholog); blastocyst development (ortholog); blood vessel development (ortholog); PARTICIPATES IN transforming growth factor-beta Smad dependent signaling pathway; ASSOCIATED WITH connective tissue disease (ortholog); COVID-19 (ortholog); endometrial adenocarcinoma (ortholog); FOUND IN cell surface (ortholog); cytoplasm (ortholog); endoplasmic reticulum (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: transforming growth factor beta receptor type 3
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405058101,608,922 - 101,793,829 (-)NCBI
SpeTri2.0NW_0049365377,154,125 - 7,340,218 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
animal organ regeneration  (ISO)
blastocyst development  (ISO)
blood vessel development  (ISO)
blood vessel remodeling  (ISO)
BMP signaling pathway  (ISO)
cardiac epithelial to mesenchymal transition  (ISO)
cardiac muscle cell proliferation  (ISO)
collagen metabolic process  (ISO)
definitive erythrocyte differentiation  (ISO)
definitive hemopoiesis  (ISO)
epicardium-derived cardiac fibroblast cell development  (ISO)
epithelial to mesenchymal transition  (ISO)
heart trabecula formation  (ISO)
heart trabecula morphogenesis  (ISO)
immune response  (ISO)
in utero embryonic development  (ISO)
intracellular signal transduction  (ISO)
liver development  (ISO)
muscular septum morphogenesis  (ISO)
negative regulation of apoptotic process involved in morphogenesis  (ISO)
negative regulation of cellular component movement  (ISO)
negative regulation of epithelial cell migration  (ISO)
negative regulation of epithelial cell proliferation  (ISO)
negative regulation of epithelial to mesenchymal transition  (ISO)
negative regulation of gene expression  (ISO)
negative regulation of transforming growth factor beta receptor signaling pathway  (ISO)
osteoblast differentiation  (ISO)
outflow tract morphogenesis  (ISO)
pathway-restricted SMAD protein phosphorylation  (ISO)
positive regulation of BMP signaling pathway  (ISO)
positive regulation of cardiac muscle cell proliferation  (ISO)
positive regulation of cell population proliferation  (ISO)
positive regulation of NF-kappaB transcription factor activity  (ISO)
positive regulation of transforming growth factor beta receptor signaling pathway  (ISO)
protein-containing complex assembly  (ISO)
regulation of ERK1 and ERK2 cascade  (ISO)
regulation of JNK cascade  (ISO)
regulation of protein binding  (ISO)
response to follicle-stimulating hormone  (ISO)
response to hypoxia  (ISO)
response to luteinizing hormone  (ISO)
response to prostaglandin E  (ISO)
roof of mouth development  (ISO)
secondary palate development  (ISO)
transforming growth factor beta receptor complex assembly  (ISO)
transforming growth factor beta receptor signaling pathway  (ISO)
vasculogenesis  (ISO)
vasculogenesis involved in coronary vascular morphogenesis  (ISO)
ventricular cardiac muscle tissue morphogenesis  (ISO)
ventricular compact myocardium morphogenesis  (ISO)
ventricular septum morphogenesis  (ISO)

Molecular Pathway Annotations     Click to see Annotation Detail View
References

Genomics

Comparative Map Data
Tgfbr3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405058101,608,922 - 101,793,829 (-)NCBI
SpeTri2.0NW_0049365377,154,125 - 7,340,218 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TGFBR3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl191,680,343 - 91,906,335 (-)EnsemblGRCh38hg38GRCh38
GRCh38191,680,343 - 91,906,002 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37192,145,900 - 92,371,559 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36191,920,575 - 92,124,243 (-)NCBINCBI36hg18NCBI36
Build 34191,860,007 - 92,063,676NCBI
Celera190,391,974 - 90,597,757 (-)NCBI
Cytogenetic Map1p22.1NCBI
HuRef190,263,929 - 90,491,182 (-)NCBIHuRef
CHM1_1192,261,010 - 92,486,411 (-)NCBICHM1_1
Tgfbr3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395107,254,433 - 107,437,495 (-)NCBIGRCm39mm39
GRCm39 Ensembl5107,254,436 - 107,437,495 (-)Ensembl
GRCm385107,106,567 - 107,289,629 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5107,106,570 - 107,289,629 (-)EnsemblGRCm38mm10GRCm38
MGSCv375107,535,589 - 107,718,614 (-)NCBIGRCm37mm9NCBIm37
MGSCv365107,346,872 - 107,529,822 (-)NCBImm8
Celera5104,218,970 - 104,402,013 (-)NCBICelera
Cytogenetic Map5E5NCBI
Tgfbr3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2142,489,397 - 2,665,383 (+)NCBI
Rnor_6.0 Ensembl143,506,339 - 3,682,545 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0143,506,416 - 3,680,508 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0143,509,601 - 3,683,814 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4143,051,039 - 3,240,286 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1143,051,038 - 3,240,286 (+)NCBI
Celera142,505,821 - 2,679,576 (+)NCBICelera
Cytogenetic Map14p22NCBI
Tgfbr3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554232,573,795 - 2,765,772 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554232,573,851 - 2,765,353 (+)NCBIChiLan1.0ChiLan1.0
TGFBR3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1193,080,452 - 93,285,587 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl193,080,452 - 93,285,587 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0194,337,275 - 94,539,229 (-)NCBIMhudiblu_PPA_v0panPan3
TGFBR3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1657,025,096 - 57,220,240 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl657,025,112 - 57,217,121 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha659,730,730 - 59,925,446 (+)NCBI
ROS_Cfam_1.0657,407,397 - 57,602,731 (+)NCBI
UMICH_Zoey_3.1657,084,907 - 57,279,569 (+)NCBI
UNSW_CanFamBas_1.0657,060,369 - 57,254,710 (+)NCBI
UU_Cfam_GSD_1.0657,523,587 - 57,718,361 (+)NCBI
TGFBR3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl4125,101,190 - 125,316,796 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.14125,109,939 - 125,310,788 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.24136,671,290 - 136,820,333 (+)NCBISscrofa10.2Sscrofa10.2susScr3
TGFBR3
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12041,353,182 - 41,565,357 (+)NCBI
ChlSab1.1 Ensembl2041,353,325 - 41,565,343 (+)Ensembl
Vero_WHO_p1.0NW_02366603376,431,842 - 76,637,238 (-)NCBI
Tgfbr3
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247425,871,155 - 6,080,773 (+)NCBI


Expression


Sequence


Reference Sequences
RefSeq Acc Id: XM_013359732   ⟹   XP_013215186
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024405058101,608,922 - 101,793,826 (-)NCBI
SpeTri2.0NW_0049365377,154,125 - 7,340,218 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013359733   ⟹   XP_013215187
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024405058101,611,078 - 101,793,829 (-)NCBI
SpeTri2.0NW_0049365377,154,125 - 7,340,218 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021728019   ⟹   XP_021583694
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024405058101,611,078 - 101,793,470 (-)NCBI
SpeTri2.0NW_0049365377,154,505 - 7,340,218 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021728020   ⟹   XP_021583695
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024405058101,611,078 - 101,793,470 (-)NCBI
SpeTri2.0NW_0049365377,154,505 - 7,340,218 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_013215186 (Get FASTA)   NCBI Sequence Viewer  
  XP_013215187 (Get FASTA)   NCBI Sequence Viewer  
  XP_021583694 (Get FASTA)   NCBI Sequence Viewer  
  XP_021583695 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_013215186   ⟸   XM_013359732
- Sequence:
RefSeq Acc Id: XP_013215187   ⟸   XM_013359733
- Sequence:
RefSeq Acc Id: XP_021583694   ⟸   XM_021728019
- Sequence:
RefSeq Acc Id: XP_021583695   ⟸   XM_021728020
- Sequence:
Protein Domains
ZP


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000011061 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSSTOP00000015408 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000022388 UniProtKB/TrEMBL
InterPro ZP_dom UniProtKB/TrEMBL
  ZP_dom_CS UniProtKB/TrEMBL
NCBI Gene Tgfbr3 ENTREZGENE
Pfam Zona_pellucida UniProtKB/TrEMBL
PRINTS ZPELLUCIDA UniProtKB/TrEMBL
PROSITE ZP_1 UniProtKB/TrEMBL
  ZP_2 UniProtKB/TrEMBL
SMART SM00241 UniProtKB/TrEMBL
UniProt I3MTG3_ICTTR UniProtKB/TrEMBL